# Atropine maintenance infusion

Atropine maintenance infusion

Status: LIVE
Price: $0.005 USDC
`GET /api/calc/atropine_op`
HTML: https://magentlab.com/docs/atropine-op
Markdown: https://magentlab.com/docs/atropine-op.md

Not a medical device. Not a diagnosis, dose, or listing recommendation.

## What it computes

Compute the Eddleston 2004 atropine maintenance infusion band (10-20% of the total atropine required to stabilize, every hour) from a caller-assigned loading milligram amount. Not doubling-bolus titration.

## When to use

When an agent needs the Eddleston 2004 hourly atropine maintenance band from a caller-assigned total loading milligram amount and must not invent doubling-bolus titration, pralidoxime, or a diagnosis of organophosphate poisoning.

## When not to use

- Not a medical device. A licensed clinician remains responsible for interpretation.
- Not a prescription. magent does not choose a vial, route, or infusion pump setting.
- Not doubling-bolus titration. Loading boluses are bedside titration; this tool is the post-stabilization hourly infusion band only.
- Not pralidoxime. magent does not compute oxime dose.
- magent does not examine the chest or pulse and does not diagnose organophosphate poisoning.

## Formula

```
infusion_low_mg_h = 0.10 * atropine_load_mg; infusion_high_mg_h = 0.20 * atropine_load_mg
```

## Citation

[Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors](https://doi.org/10.1186/cc2953)
Eddleston M, Dawson A, Karalliedde L, Dissanayake W, Hittarage A, Azher S, Buckley NA
Crit Care. 2004;8(6):R391-R397
DOI: [10.1186/cc2953](https://doi.org/10.1186/cc2953)

## Worked example

### 18 mg atropine load

Given: `atropine_load_mg=18`

1. infusion_low_mg_h = 0.10 * 18 = 1.8 mg/h
2. infusion_high_mg_h = 0.20 * 18 = 3.6 mg/h


### 10 mg atropine load

Given: `atropine_load_mg=10`

1. infusion_low_mg_h = 0.10 * 10 = 1.0 mg/h
2. infusion_high_mg_h = 0.20 * 10 = 2.0 mg/h


## Also searched as

- atropine infusion
- atropine maintenance
- organophosphate atropine
- Eddleston atropine
- cholinesterase inhibitor atropine
- atropine load infusion
- pesticide atropine protocol

## Parameters

- `atropine_load_mg` (number, required): Caller-assigned total atropine loading milligrams already used to stabilize (0.6-200). magent does not choose loading boluses.

## Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

Method: `POST /api/calc/atropine_op`
Max items: 25
Price: unit_amount + extra_item_amount * (n - 1) (unit 5000 atomic, extra 2000 atomic)
Status: PREVIEW

- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request:

```json
{
  "items": [
    {
      "atropine_load_mg": "18"
    },
    {
      "atropine_load_mg": "18"
    }
  ]
}
```

Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/atropine-op

Example 200:

```json
{
  "count": 2,
  "path": "/api/calc/atropine_op",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Eddleston M, Dawson A, Karalliedde L, Dissanayake W, Hittarage A, Azher S, Buckley NA",
        "doi": "10.1186/cc2953",
        "id": "eddleston-2004",
        "pmid": "15569362",
        "source": "Crit Care. 2004;8(6):R391-R397",
        "title": "Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors"
      },
      "formula": "eddleston_2004",
      "formula_expression": "infusion_low_mg_h = 0.10 * atropine_load_mg; infusion_high_mg_h = 0.20 * atropine_load_mg",
      "atropine_load_mg": 18.0,
      "infusion_high_mg_h": 3.6,
      "infusion_low_mg_h": 1.8
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Eddleston M, Dawson A, Karalliedde L, Dissanayake W, Hittarage A, Azher S, Buckley NA",
        "doi": "10.1186/cc2953",
        "id": "eddleston-2004",
        "pmid": "15569362",
        "source": "Crit Care. 2004;8(6):R391-R397",
        "title": "Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors"
      },
      "formula": "eddleston_2004",
      "formula_expression": "infusion_low_mg_h = 0.10 * atropine_load_mg; infusion_high_mg_h = 0.20 * atropine_load_mg",
      "atropine_load_mg": 18.0,
      "infusion_high_mg_h": 3.6,
      "infusion_low_mg_h": 1.8
    }
  ]
}
```

## Response fields

- `formula` (string): eddleston_2004
- `formula_expression` (string): Exact 10% and 20% expressions
- `atropine_load_mg` (number): Caller-assigned total atropine loading milligrams used
- `infusion_low_mg_h` (number): 10% of atropine_load_mg as mg/h, 1 decimal
- `infusion_high_mg_h` (number): 20% of atropine_load_mg as mg/h, 1 decimal
- `citation` (object): Eddleston 2004 citation
- `disclaimer` (string): Not-a-device notice

## Example JSON

Frozen fixture. Not a live lookup.

```json
{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Eddleston M, Dawson A, Karalliedde L, Dissanayake W, Hittarage A, Azher S, Buckley NA",
    "doi": "10.1186/cc2953",
    "id": "eddleston-2004",
    "pmid": "15569362",
    "source": "Crit Care. 2004;8(6):R391-R397",
    "title": "Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors"
  },
  "formula": "eddleston_2004",
  "formula_expression": "infusion_low_mg_h = 0.10 * atropine_load_mg; infusion_high_mg_h = 0.20 * atropine_load_mg",
  "atropine_load_mg": 18.0,
  "infusion_high_mg_h": 3.6,
  "infusion_low_mg_h": 1.8
}
```

## Errors

- HTTP 400 `invalid_atropine`: Atropine infusion inputs must match Eddleston 2004 total loading milligrams from that protocol. Returned before settlement; you are not charged.
- HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
- HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
- HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged.

Shared HTTP 402 and 503: https://magentlab.com/docs/payments

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## Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s.

- GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall).
- HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote.
- Sign accepts[0] (exact, EIP-3009) with validBefore = now + maxTimeoutSeconds (600 seconds), or accepts[1] (batch-settlement deposit/voucher) on product GET. Ping and POST {items} stay exact. Magent retries transient facilitator 429/5xx before answering.
- Retry the same URL with PAYMENT-SIGNATURE (base64 JSON of accepted and payload). Magent attaches canonical extensions.bazaar on CDP verify/settle; echoing 402 bazaar is optional.
- Success is HTTP 200 JSON plus PAYMENT-RESPONSE. exact settles before the tool. batch-settlement verifies (and deposit-settles) before the tool and commits the charge after HTTP 2xx. HTTP 503: retry the same PAYMENT-SIGNATURE. Mint a new exact nonce only after a new HTTP 402.

- offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront.
- offered `batch-settlement` on eip155:8453: Payment-channel vouchers claimed later in batches. Exact stays accepts[0]. Same-path POST {items} is still exact. extra.assetTransferMethod=eip3009 extra.paymentFlow=authorization.

- not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search.

Same-path POST {items} is still scheme exact: one EIP-3009 authorization for GET unit plus $0.002 per extra item. That is not x402 batch-settlement (payment channels / vouchers).

Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments

Stdio MCP (one process per host): https://magentlab.com/docs/mcp

## Guarantees

- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.