# Centor and McIsaac scores

Status: LIVE
Price: $0.005 USDC
`GET /api/calc/centor`
HTML: https://magentlab.com/docs/centor
Markdown: https://magentlab.com/docs/centor.md

Not a medical device. Not a diagnosis, dose, or listing recommendation.

## What it computes

Compute the Centor score or the McIsaac age-modified score from four caller-assigned pharyngitis findings. The edition is required.

## When to use

When an agent needs a published Centor or McIsaac total and must not silently pick an edition or invent the four clinical findings.

## When not to use

- Not a test-or-treat protocol and not a diagnosis of streptococcal pharyngitis.
- The caller assigns the four clinical findings. magent does not examine the throat.
- McIsaac age bands are 3-14 / 15-44 / >=45 as published. edition is required; magent does not pick Centor or McIsaac.

## Formula

```
McIsaac = Centor criteria + age 3-14 +1, 15-44 0, >=45 -1; max 5
```

## Citation

Empirical validation of guidelines for the management of pharyngitis in children and adults
McIsaac WJ, Kellner JD, Aufricht P, Vanjaka A, Low DE
JAMA. 2004;291(13):1587-1595
DOI: [10.1001/jama.291.13.1587](https://doi.org/10.1001/jama.291.13.1587)

## Worked example

### McIsaac adult all-negative

Given: `age=30, cough_absent=false, edition=mcisaac, history_of_fever=false, tender_anterior_cervical_nodes=false, tonsillar_exudates=false`

1. Four findings absent; age 30 is 15-44 → 0
2. Score = 0 (max 5)


### Centor all four present

Given: `cough_absent=true, edition=centor, history_of_fever=true, tender_anterior_cervical_nodes=true, tonsillar_exudates=true`

1. Four findings present → 1 each
2. Score = 4 (max 4)


### McIsaac child all-negative

Given: `age=8, cough_absent=false, edition=mcisaac, history_of_fever=false, tender_anterior_cervical_nodes=false, tonsillar_exudates=false`

1. Four findings absent; age 8 is 3-14 → +1
2. Score = 1


## Parameters

- `edition` (string, required): Published score. Required; magent does not pick Centor (four findings, max 4) or McIsaac (age-modified, max 5).
- `age` (integer, optional): Age in years (3-120). Required when edition=mcisaac (3-14 +1, 15-44 0, >=45 -1). Ignored when edition=centor.
- `tonsillar_exudates` (boolean, required): Tonsillar exudates. true or false as assigned by the caller.
- `tender_anterior_cervical_nodes` (boolean, required): Tender anterior cervical nodes. true or false as assigned by the caller.
- `history_of_fever` (boolean, required): History of fever. true or false as assigned by the caller.
- `cough_absent` (boolean, required): Absence of cough. true when cough is absent; false when cough is present.

## Bulk (POST)

POST the same path with a JSON items array. Price is n times the GET unit. Invalid items return HTTP 400 before settlement.

Method: `POST /api/calc/centor`
Max items: 25
Price: unit_amount * n (unit 5000 atomic)
Status: PREVIEW

- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request:

```json
{
  "items": [
    {
      "age": "30",
      "cough_absent": "false",
      "edition": "mcisaac",
      "history_of_fever": "false",
      "tender_anterior_cervical_nodes": "false",
      "tonsillar_exudates": "false"
    },
    {
      "age": "30",
      "cough_absent": "false",
      "edition": "mcisaac",
      "history_of_fever": "false",
      "tender_anterior_cervical_nodes": "false",
      "tonsillar_exudates": "false"
    }
  ]
}
```

Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/centor

Example 200:

```json
{
  "count": 2,
  "path": "/api/calc/centor",
  "items": [
    {
      "components": [
        {
          "factor": "tonsillar_exudates",
          "points": 0,
          "present": false
        },
        {
          "factor": "tender_anterior_cervical_nodes",
          "points": 0,
          "present": false
        },
        {
          "factor": "history_of_fever",
          "points": 0,
          "present": false
        },
        {
          "factor": "cough_absent",
          "points": 0,
          "present": false
        },
        {
          "value": 30,
          "factor": "age_adjustment",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "McIsaac WJ, Kellner JD, Aufricht P, Vanjaka A, Low DE",
        "doi": "10.1001/jama.291.13.1587",
        "id": "mcisaac-2004",
        "source": "JAMA. 2004;291(13):1587-1595",
        "title": "Empirical validation of guidelines for the management of pharyngitis in children and adults"
      },
      "formula": "mcisaac",
      "formula_expression": "McIsaac = Centor criteria + age 3-14 +1, 15-44 0, >=45 -1; max 5",
      "max_score": 5,
      "score": 0,
      "edition": "mcisaac",
      "age_years": 30
    },
    {
      "components": [
        {
          "factor": "tonsillar_exudates",
          "points": 0,
          "present": false
        },
        {
          "factor": "tender_anterior_cervical_nodes",
          "points": 0,
          "present": false
        },
        {
          "factor": "history_of_fever",
          "points": 0,
          "present": false
        },
        {
          "factor": "cough_absent",
          "points": 0,
          "present": false
        },
        {
          "value": 30,
          "factor": "age_adjustment",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "McIsaac WJ, Kellner JD, Aufricht P, Vanjaka A, Low DE",
        "doi": "10.1001/jama.291.13.1587",
        "id": "mcisaac-2004",
        "source": "JAMA. 2004;291(13):1587-1595",
        "title": "Empirical validation of guidelines for the management of pharyngitis in children and adults"
      },
      "formula": "mcisaac",
      "formula_expression": "McIsaac = Centor criteria + age 3-14 +1, 15-44 0, >=45 -1; max 5",
      "max_score": 5,
      "score": 0,
      "edition": "mcisaac",
      "age_years": 30
    }
  ]
}
```

## Response fields

- `formula` (string): centor or mcisaac
- `formula_expression` (string): Exact expression used
- `edition` (string): centor or mcisaac
- `score` (integer): Total points (0-4 Centor; -1 to 5 McIsaac)
- `max_score` (integer): 4 (Centor) or 5 (McIsaac)
- `age_years` (integer): Age used for McIsaac bands. Present when edition=mcisaac.
- `components` (array): Per-finding points
- `citation` (object): Centor 1981 or McIsaac 2004
- `disclaimer` (string): Not-a-device notice

## Example JSON

Frozen fixture. Not a live lookup.

```json
{
  "components": [
    {
      "factor": "tonsillar_exudates",
      "points": 0,
      "present": false
    },
    {
      "factor": "tender_anterior_cervical_nodes",
      "points": 0,
      "present": false
    },
    {
      "factor": "history_of_fever",
      "points": 0,
      "present": false
    },
    {
      "factor": "cough_absent",
      "points": 0,
      "present": false
    },
    {
      "value": 30,
      "factor": "age_adjustment",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "McIsaac WJ, Kellner JD, Aufricht P, Vanjaka A, Low DE",
    "doi": "10.1001/jama.291.13.1587",
    "id": "mcisaac-2004",
    "source": "JAMA. 2004;291(13):1587-1595",
    "title": "Empirical validation of guidelines for the management of pharyngitis in children and adults"
  },
  "formula": "mcisaac",
  "formula_expression": "McIsaac = Centor criteria + age 3-14 +1, 15-44 0, >=45 -1; max 5",
  "max_score": 5,
  "score": 0,
  "edition": "mcisaac",
  "age_years": 30
}
```

## Errors

- HTTP 400 `invalid_centor_edition`: edition must be centor or mcisaac. Returned before settlement; you are not charged.
- HTTP 400 `invalid_flag`: boolean clinical flags must be true or false Returned before settlement; you are not charged.
- HTTP 400 `invalid_centor_age`: age must be an integer from 3 to 120 (McIsaac). Returned before settlement; you are not charged.
- HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
- HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
- HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged.
- HTTP 402 `payment_required`: Missing or invalid PAYMENT-SIGNATURE; decode the PAYMENT-REQUIRED header
- HTTP 409 `payment_in_progress`: The same authorization nonce is already being settled; retry shortly
- HTTP 429 `rate_limited`: Too many requests from this client
- HTTP 503 `settlement_uncertain`: Settlement is unconfirmed; retry with the same PAYMENT-SIGNATURE
- HTTP 503 `settle_failed`: Settlement failed; retry with the same PAYMENT-SIGNATURE shortly
- HTTP 503 `facilitator_unavailable`: Payment facilitator unavailable
- HTTP 503 `facilitator_misconfigured`: Payment facilitator is not configured
- HTTP 503 `facilitator_unauthorized`: Payment facilitator rejected credentials
- HTTP 503 `ledger_unavailable`: Payment ledger unavailable
- HTTP 503 `payment_unavailable`: Payment processing unavailable

## Related tools

- [CURB-65](https://magentlab.com/docs/curb65) — Compute the CURB-65 community-acquired pneumonia severity score from age and discrete flags.

## Also searched as

- Centor score
- McIsaac score
- modified Centor score
- strep pharyngitis score
- streptococcal pharyngitis criteria
- tonsillar exudates tender nodes

## Payment

Required query parameters must be present and valid. Invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s.

- GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall).
- HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote.
- Sign EIP-3009 (scheme exact, assetTransferMethod eip3009) with validBefore = now + accepts[0].maxTimeoutSeconds (600 seconds). That window starts when you sign and must cover wallet confirmation plus CDP verify and settle. Magent retries transient facilitator 429/5xx before answering. Do not send upto or batch-settlement payloads; magent does not offer those schemes.
- Retry the same URL with PAYMENT-SIGNATURE (base64 JSON echoing accepted, payload, and extensions when present).
- Success is HTTP 200 JSON plus PAYMENT-RESPONSE. Settlement happens before the tool runs. HTTP 503 settlement_uncertain or settle_failed: retry the same PAYMENT-SIGNATURE. Mint a new nonce only after a new HTTP 402.

- offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront.

- not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search.
- not offered `batch-settlement`: Not offered. Payment-channel vouchers claimed later in batches. Not the same as POST {items} bulk (that is still exact).

Same-path POST {items} is still scheme exact: one EIP-3009 authorization for n times the GET unit. That is not x402 batch-settlement (payment channels / vouchers).

## Guarantees

- Invalid query parameters return HTTP 400 before settlement. You are not charged.
- Settlement finishes before the tool executes (paymentFlow upfront). Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.
