# CHADS-65

CHADS-65

Status: LIVE
Price: $0.005 USDC
`GET /api/calc/chads_65`
HTML: https://magentlab.com/docs/chads-65
Markdown: https://magentlab.com/docs/chads-65.md

Not a medical device. Not a diagnosis, dose, or listing recommendation.

## What it computes

Apply the CCS 2014 CHADS-65 algorithm and return oac, asa, or none from age and caller-assigned CHF, hypertension, diabetes, prior stroke/TIA, and vascular disease.

## When to use

When an agent needs the CCS 2014 CHADS-65 stroke-prevention algorithm for nonvalvular AF/AFL from caller-assigned age and flags, and must not use CHADS2, CHA2DS2-VASc, or HAS-BLED.

## When not to use

- Not a medical device. Not an anticoagulation order. magent does not examine the patient.
- This is the Canadian CCS 2014 algorithm for nonvalvular AF/AFL stroke-prevention discussion. It is not CHADS2, not CHA2DS2-VASc, not HAS-BLED, and not a valve or AF diagnosis.
- Age ≥75 is subsumed by age ≥65. There is no separate age≥75 input.
- Flags are caller-supplied booleans. magent does not infer CHF, stroke, or vascular disease from text.

## Formula

```
OAC if age ≥ 65 or CHF or hypertension or diabetes or prior stroke/TIA; else ASA if vascular disease (coronary, aortic, or peripheral arterial); else none (CCS 2014 CHADS-65)
```

## Citation

[2014 focused update of the Canadian Cardiovascular Society Guidelines for the management of atrial fibrillation](https://doi.org/10.1016/j.cjca.2014.08.001)
Verma A, Cairns JA, Mitchell LB, Macle L, Stiell IG, Gladstone D, McMurtry MS, Connolly S, Cox JL, Dorian P, Ivers N, Leblanc K, Nattel S, Healey JS
Can J Cardiol. 2014;30(10):1114-1130
DOI: [10.1016/j.cjca.2014.08.001](https://doi.org/10.1016/j.cjca.2014.08.001)

## Worked example

### Age 70, all flags false

Given: `age=70, chf=false, diabetes=false, hypertension=false, stroke_tia=false, vascular_disease=false`

1. Age 70 ≥ 65
2. recommendation is oac


### Age 50 with vascular disease

Given: `age=50, chf=false, diabetes=false, hypertension=false, stroke_tia=false, vascular_disease=true`

1. Age 50 is not ≥ 65; no CHF, hypertension, diabetes, or stroke/TIA
2. vascular_disease is true; recommendation is asa


### Age 50, all flags false

Given: `age=50, chf=false, diabetes=false, hypertension=false, stroke_tia=false, vascular_disease=false`

1. Age 50 is not ≥ 65; no CHADS2 factors and no vascular disease
2. recommendation is none


### Age 50 with diabetes

Given: `age=50, chf=false, diabetes=true, hypertension=false, stroke_tia=false, vascular_disease=false`

1. Age 50 is not ≥ 65; diabetes is a CHADS2 factor other than age≥75
2. recommendation is oac


## Also searched as

- CHADS-65
- CCS algorithm
- CCS AF
- CCS CHADS-65
- CHADS65
- Canadian AF guidelines
- CCS atrial fibrillation
- Verma 2014 AF

## Parameters

- `age` (integer, required): Age in years (18-120). ≥65 indicates oral anticoagulant (OAC). Age ≥75 is subsumed by ≥65; there is no separate age≥75 input. 64 does not indicate OAC on age alone.
- `chf` (boolean, required): Congestive heart failure as assigned by the caller. true or false. Any true CHADS2 factor other than age≥75 (CHF, hypertension, diabetes, prior stroke/TIA) indicates OAC.
- `hypertension` (boolean, required): Hypertension history as assigned by the caller. true or false. Indicates OAC when true.
- `diabetes` (boolean, required): Diabetes mellitus as assigned by the caller. true or false. Indicates OAC when true.
- `stroke_tia` (boolean, required): Prior stroke or TIA as assigned by the caller. true or false. Indicates OAC when true.
- `vascular_disease` (boolean, required): Coronary, aortic, or peripheral arterial disease as assigned by the caller. true or false. Indicates ASA only when OAC is not indicated.

## Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

Method: `POST /api/calc/chads_65`
Max items: 25
Price: unit_amount + extra_item_amount * (n - 1) (unit 5000 atomic, extra 2000 atomic)
Status: PREVIEW

- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request:

```json
{
  "items": [
    {
      "age": "70",
      "chf": "false",
      "diabetes": "false",
      "hypertension": "false",
      "stroke_tia": "false",
      "vascular_disease": "false"
    },
    {
      "age": "70",
      "chf": "false",
      "diabetes": "false",
      "hypertension": "false",
      "stroke_tia": "false",
      "vascular_disease": "false"
    }
  ]
}
```

Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/chads-65

Example 200:

```json
{
  "count": 2,
  "path": "/api/calc/chads_65",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Verma A, Cairns JA, Mitchell LB, Macle L, Stiell IG, Gladstone D, McMurtry MS, Connolly S, Cox JL, Dorian P, Ivers N, Leblanc K, Nattel S, Healey JS",
        "doi": "10.1016/j.cjca.2014.08.001",
        "id": "verma-2014",
        "pmid": "25262857",
        "source": "Can J Cardiol. 2014;30(10):1114-1130",
        "title": "2014 focused update of the Canadian Cardiovascular Society Guidelines for the management of atrial fibrillation"
      },
      "formula": "chads_65",
      "formula_expression": "OAC if age ≥ 65 or CHF or hypertension or diabetes or prior stroke/TIA; else ASA if vascular disease (coronary, aortic, or peripheral arterial); else none (CCS 2014 CHADS-65)",
      "criteria": [
        {
          "value": 70,
          "factor": "age_ge_65",
          "met": true
        },
        {
          "factor": "chf",
          "met": false
        },
        {
          "factor": "hypertension",
          "met": false
        },
        {
          "factor": "diabetes",
          "met": false
        },
        {
          "factor": "stroke_tia",
          "met": false
        },
        {
          "factor": "vascular_disease",
          "met": false
        }
      ],
      "oac_indicated": true,
      "recommendation": "oac"
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Verma A, Cairns JA, Mitchell LB, Macle L, Stiell IG, Gladstone D, McMurtry MS, Connolly S, Cox JL, Dorian P, Ivers N, Leblanc K, Nattel S, Healey JS",
        "doi": "10.1016/j.cjca.2014.08.001",
        "id": "verma-2014",
        "pmid": "25262857",
        "source": "Can J Cardiol. 2014;30(10):1114-1130",
        "title": "2014 focused update of the Canadian Cardiovascular Society Guidelines for the management of atrial fibrillation"
      },
      "formula": "chads_65",
      "formula_expression": "OAC if age ≥ 65 or CHF or hypertension or diabetes or prior stroke/TIA; else ASA if vascular disease (coronary, aortic, or peripheral arterial); else none (CCS 2014 CHADS-65)",
      "criteria": [
        {
          "value": 70,
          "factor": "age_ge_65",
          "met": true
        },
        {
          "factor": "chf",
          "met": false
        },
        {
          "factor": "hypertension",
          "met": false
        },
        {
          "factor": "diabetes",
          "met": false
        },
        {
          "factor": "stroke_tia",
          "met": false
        },
        {
          "factor": "vascular_disease",
          "met": false
        }
      ],
      "oac_indicated": true,
      "recommendation": "oac"
    }
  ]
}
```

## Response fields

- `formula` (string): chads_65
- `formula_expression` (string): CCS 2014 CHADS-65 OAC then ASA then none tree
- `recommendation` (string): oac, asa, or none. Not an anticoagulation order.
- `oac_indicated` (boolean): true when age ≥ 65 or CHF, hypertension, diabetes, or prior stroke/TIA is present
- `criteria` (array): Per-factor rows (age_ge_65, chf, hypertension, diabetes, stroke_tia, vascular_disease) with factor, met, and age value on age_ge_65
- `citation` (object): Verma 2014 Can J Cardiol citation
- `disclaimer` (string): Not-a-device notice

## Example JSON

Frozen fixture. Not a live lookup.

```json
{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Verma A, Cairns JA, Mitchell LB, Macle L, Stiell IG, Gladstone D, McMurtry MS, Connolly S, Cox JL, Dorian P, Ivers N, Leblanc K, Nattel S, Healey JS",
    "doi": "10.1016/j.cjca.2014.08.001",
    "id": "verma-2014",
    "pmid": "25262857",
    "source": "Can J Cardiol. 2014;30(10):1114-1130",
    "title": "2014 focused update of the Canadian Cardiovascular Society Guidelines for the management of atrial fibrillation"
  },
  "formula": "chads_65",
  "formula_expression": "OAC if age ≥ 65 or CHF or hypertension or diabetes or prior stroke/TIA; else ASA if vascular disease (coronary, aortic, or peripheral arterial); else none (CCS 2014 CHADS-65)",
  "criteria": [
    {
      "value": 70,
      "factor": "age_ge_65",
      "met": true
    },
    {
      "factor": "chf",
      "met": false
    },
    {
      "factor": "hypertension",
      "met": false
    },
    {
      "factor": "diabetes",
      "met": false
    },
    {
      "factor": "stroke_tia",
      "met": false
    },
    {
      "factor": "vascular_disease",
      "met": false
    }
  ],
  "oac_indicated": true,
  "recommendation": "oac"
}
```

## Errors

- HTTP 400 `invalid_age`: age must be an integer from 18 to 120 Returned before settlement; you are not charged.
- HTTP 400 `invalid_flag`: boolean clinical flags must be true or false Returned before settlement; you are not charged.
- HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
- HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
- HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged.

Shared HTTP 402 and 503: https://magentlab.com/docs/payments

## Related tools

- [CHADS2](https://magentlab.com/docs/chads2) — Compute the CHADS2 stroke-risk score from discrete clinical flags.
- [CHA2DS2-VASc](https://magentlab.com/docs/cha2ds2-vasc) — Compute the CHA2DS2-VASc stroke-risk score from discrete clinical flags.

## Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s.

- GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall).
- HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote.
- Sign accepts[0] (exact, EIP-3009) with validBefore = now + maxTimeoutSeconds (600 seconds), or accepts[1] (batch-settlement deposit/voucher) on product GET. Ping and POST {items} stay exact. Magent retries transient facilitator 429/5xx before answering.
- Retry the same URL with PAYMENT-SIGNATURE (base64 JSON of accepted and payload). Magent attaches canonical extensions.bazaar on CDP verify/settle; echoing 402 bazaar is optional.
- Success is HTTP 200 JSON plus PAYMENT-RESPONSE. exact settles before the tool. batch-settlement verifies (and deposit-settles) before the tool and commits the charge after HTTP 2xx. HTTP 503: retry the same PAYMENT-SIGNATURE. Mint a new exact nonce only after a new HTTP 402.

- offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront.
- offered `batch-settlement` on eip155:8453: Payment-channel vouchers claimed later in batches. Exact stays accepts[0]. Same-path POST {items} is still exact. extra.assetTransferMethod=eip3009 extra.paymentFlow=authorization.

- not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search.

Same-path POST {items} is still scheme exact: one EIP-3009 authorization for GET unit plus $0.002 per extra item. That is not x402 batch-settlement (payment channels / vouchers).

Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments

Stdio MCP (one process per host): https://magentlab.com/docs/mcp

## Guarantees

- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.
