# Cerebral perfusion pressure

CPP

Status: LIVE
Price: $0.005 USDC
`GET /api/calc/cpp`
HTML: https://magentlab.com/docs/cpp
Markdown: https://magentlab.com/docs/cpp.md

Not a medical device. Not a diagnosis, dose, or listing recommendation.

## What it computes

Compute cerebral perfusion pressure as MAP minus ICP in mm Hg and flag whether CPP is at least 70 mm Hg per Rosner 1995.

## When to use

When an agent has caller-supplied MAP and ICP in mm Hg and needs the published CPP identity and the Rosner 1995 minimum-CPP-of-70 flag, not a monitor reading or a treatment order.

## When not to use

- Not a medical device. Not a treatment protocol.
- map_mm_hg and icp_mm_hg are caller-supplied. magent does not measure MAP or ICP and is not an invasive monitor.
- cpp_ge_70 is the Rosner 1995 protocol minimum CPP of at least 70 mm Hg. It is not a later target.
- CPP may be negative when ICP exceeds MAP. That is not a validation error.

## Formula

```
cpp_mm_hg = map_mm_hg - icp_mm_hg
```

## Citation

[Cerebral perfusion pressure: management protocol and clinical results](https://doi.org/10.3171/jns.1995.83.6.0949)
Rosner MJ, Rosner SD, Johnson AH
J Neurosurg. 1995;83(6):949-962
DOI: [10.3171/jns.1995.83.6.0949](https://doi.org/10.3171/jns.1995.83.6.0949)

## Worked example

### MAP 90, ICP 10

Given: `icp_mm_hg=10, map_mm_hg=90`

1. cpp_mm_hg = 90 − 10 = 80 → 80.0
2. 80.0 ≥ 70 → cpp_ge_70 true


## Also searched as

- cerebral perfusion pressure
- CPP
- MAP minus ICP
- cerebral perfusion
- Rosner CPP
- intracranial pressure CPP
- CPP mm Hg

## Parameters

- `map_mm_hg` (number, required): Mean arterial pressure in mm Hg (30-180). Caller-supplied; magent does not measure MAP.
- `icp_mm_hg` (number, required): Intracranial pressure in mm Hg (0-100). Caller-supplied; magent does not measure ICP. ICP may exceed MAP.

## Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

Method: `POST /api/calc/cpp`
Max items: 25
Price: unit_amount + extra_item_amount * (n - 1) (unit 5000 atomic, extra 2000 atomic)
Status: PREVIEW

- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request:

```json
{
  "items": [
    {
      "icp_mm_hg": "10",
      "map_mm_hg": "90"
    },
    {
      "icp_mm_hg": "10",
      "map_mm_hg": "90"
    }
  ]
}
```

Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/cpp

Example 200:

```json
{
  "count": 2,
  "path": "/api/calc/cpp",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Rosner MJ, Rosner SD, Johnson AH",
        "doi": "10.3171/jns.1995.83.6.0949",
        "id": "rosner-1995",
        "pmid": "7490638",
        "source": "J Neurosurg. 1995;83(6):949-962",
        "title": "Cerebral perfusion pressure: management protocol and clinical results"
      },
      "formula": "cpp",
      "formula_expression": "cpp_mm_hg = map_mm_hg - icp_mm_hg",
      "cpp_ge_70": true,
      "cpp_mm_hg": 80.0,
      "icp_mm_hg": 10.0,
      "map_mm_hg": 90.0
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Rosner MJ, Rosner SD, Johnson AH",
        "doi": "10.3171/jns.1995.83.6.0949",
        "id": "rosner-1995",
        "pmid": "7490638",
        "source": "J Neurosurg. 1995;83(6):949-962",
        "title": "Cerebral perfusion pressure: management protocol and clinical results"
      },
      "formula": "cpp",
      "formula_expression": "cpp_mm_hg = map_mm_hg - icp_mm_hg",
      "cpp_ge_70": true,
      "cpp_mm_hg": 80.0,
      "icp_mm_hg": 10.0,
      "map_mm_hg": 90.0
    }
  ]
}
```

## Response fields

- `formula` (string): cpp
- `formula_expression` (string): Exact expression used
- `map_mm_hg` (number): Mean arterial pressure used, mm Hg
- `icp_mm_hg` (number): Intracranial pressure used, mm Hg
- `cpp_mm_hg` (number): Cerebral perfusion pressure in mm Hg, 1 decimal
- `cpp_ge_70` (boolean): true iff CPP is at least 70 mm Hg (Rosner 1995 protocol minimum). Not a later target.
- `citation` (object): Rosner 1995 J Neurosurg citation
- `disclaimer` (string): Not-a-device notice

## Example JSON

Frozen fixture. Not a live lookup.

```json
{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Rosner MJ, Rosner SD, Johnson AH",
    "doi": "10.3171/jns.1995.83.6.0949",
    "id": "rosner-1995",
    "pmid": "7490638",
    "source": "J Neurosurg. 1995;83(6):949-962",
    "title": "Cerebral perfusion pressure: management protocol and clinical results"
  },
  "formula": "cpp",
  "formula_expression": "cpp_mm_hg = map_mm_hg - icp_mm_hg",
  "cpp_ge_70": true,
  "cpp_mm_hg": 80.0,
  "icp_mm_hg": 10.0,
  "map_mm_hg": 90.0
}
```

## Errors

- HTTP 400 `invalid_map_mm_hg`: map_mm_hg must be a number from 30 to 180. Returned before settlement; you are not charged.
- HTTP 400 `invalid_icp_mm_hg`: icp_mm_hg must be a number from 0 to 100 (Rosner 1995 CPP). Returned before settlement; you are not charged.
- HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
- HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
- HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged.

Shared HTTP 402 and 503: https://magentlab.com/docs/payments

## Related tools

- [Glasgow Coma Scale](https://magentlab.com/docs/gcs) — Compute the Glasgow Coma Scale as the sum of caller-assigned eye, verbal, and motor integers. The 1974 or 1976 edition is required.

## Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s.

- GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall).
- HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote.
- Sign accepts[0] (exact, EIP-3009) with validBefore = now + maxTimeoutSeconds (600 seconds), or accepts[1] (batch-settlement deposit/voucher) on product GET. Ping and POST {items} stay exact. Magent retries transient facilitator 429/5xx before answering.
- Retry the same URL with PAYMENT-SIGNATURE (base64 JSON of accepted and payload). Magent attaches canonical extensions.bazaar on CDP verify/settle; echoing 402 bazaar is optional.
- Success is HTTP 200 JSON plus PAYMENT-RESPONSE. exact settles before the tool. batch-settlement verifies (and deposit-settles) before the tool and commits the charge after HTTP 2xx. HTTP 503: retry the same PAYMENT-SIGNATURE. Mint a new exact nonce only after a new HTTP 402.

- offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront.
- offered `batch-settlement` on eip155:8453: Payment-channel vouchers claimed later in batches. Exact stays accepts[0]. Same-path POST {items} is still exact. extra.assetTransferMethod=eip3009 extra.paymentFlow=authorization.

- not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search.

Same-path POST {items} is still scheme exact: one EIP-3009 authorization for GET unit plus $0.002 per extra item. That is not x402 batch-settlement (payment channels / vouchers).

Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments

Stdio MCP (one process per host): https://magentlab.com/docs/mcp

## Guarantees

- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.
