# DASH recurrent VTE

DASH

Status: LIVE
Price: $0.005 USDC
`GET /api/calc/dash`
HTML: https://magentlab.com/docs/dash
Markdown: https://magentlab.com/docs/dash.md

Not a medical device. Not a diagnosis, dose, or listing recommendation.

## What it computes

Compute the Tosetto 2012 DASH score (abnormal D-dimer after stopping anticoagulation, age <50, male sex, hormone use at the initial VTE in women) and return the published recurrence band.

## When to use

When an agent needs the published Tosetto 2012 DASH arithmetic after unprovoked VTE and must not invent a duration-of-anticoagulation decision.

## When not to use

- Not a medical device. magent does not diagnose recurrent VTE or assay D-dimer.
- Not a duration-of-anticoagulation order and not a stop-or-continue anticoagulation protocol. Recurrence bands are published Tosetto 2012 groups, not treatment instructions.
- Age scores only when <50 years (Tosetto 2012 abstract). Age 50 does not score.
- Hormone use at the initial VTE scores -2 in women only. Male with hormone_use=true is rejected.
- Abnormal D-dimer is after stopping anticoagulation as published. Percents are not returned in the JSON body.

## Formula

```
DASH = 2*abnormal_d_dimer + 1*(age<50) + 1*male + (-2)*hormone_use(female only); max 4; recurrence_band <=1 / 2 / >=3
```

## Citation

[Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH)](https://doi.org/10.1111/j.1538-7836.2012.04735.x)
Tosetto A, Iorio A, Marcucci M, et al.
J Thromb Haemost. 2012;10(6):1019-1025
DOI: [10.1111/j.1538-7836.2012.04735.x](https://doi.org/10.1111/j.1538-7836.2012.04735.x)

## Worked example

### Age 60 female, no D-dimer, no hormone use

Given: `abnormal_d_dimer=false, age=60, hormone_use=false, sex=female`

1. abnormal_d_dimer false → 0; age 60 is not <50 → 0; female → 0; hormone_use false → 0
2. Score = 0 (max 4); recurrence_band <=1


### Age 40 male with abnormal D-dimer

Given: `abnormal_d_dimer=true, age=40, hormone_use=false, sex=male`

1. abnormal_d_dimer → 2; age 40 < 50 → 1; male → 1; hormone_use false → 0
2. Score = 4 (max 4); recurrence_band >=3


## Also searched as

- DASH score
- DASH VTE
- Tosetto DASH
- recurrent VTE DASH
- DASH prediction score
- unprovoked VTE recurrence

## Parameters

- `age` (integer, required): Age in years (18-120). Scores 1 when age is <50 (Tosetto 2012). Age 50 does not score.
- `sex` (string, required): female or male. Male scores 1. Hormone use applies only when female.
- `abnormal_d_dimer` (boolean, required): Abnormal D-dimer after stopping anticoagulation (Tosetto 2012). true or false. 2 points if true.
- `hormone_use` (boolean, required): Hormone use at the initial VTE. Required. Scores -2 only when sex is female and true. Must be false when sex is male.

## Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

Method: `POST /api/calc/dash`
Max items: 25
Price: unit_amount + extra_item_amount * (n - 1) (unit 5000 atomic, extra 2000 atomic)
Status: PREVIEW

- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request:

```json
{
  "items": [
    {
      "abnormal_d_dimer": "false",
      "age": "60",
      "hormone_use": "false",
      "sex": "female"
    },
    {
      "abnormal_d_dimer": "false",
      "age": "60",
      "hormone_use": "false",
      "sex": "female"
    }
  ]
}
```

Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/dash

Example 200:

```json
{
  "count": 2,
  "path": "/api/calc/dash",
  "items": [
    {
      "components": [
        {
          "factor": "abnormal_d_dimer",
          "points": 0,
          "present": false
        },
        {
          "value": 60,
          "factor": "age_lt_50",
          "points": 0,
          "present": false
        },
        {
          "factor": "male",
          "points": 0,
          "present": false
        },
        {
          "factor": "hormone_use",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Tosetto A, Iorio A, Marcucci M, et al.",
        "doi": "10.1111/j.1538-7836.2012.04735.x",
        "id": "tosetto-2012",
        "pmid": "22489957",
        "source": "J Thromb Haemost. 2012;10(6):1019-1025",
        "title": "Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH)"
      },
      "formula": "dash",
      "formula_expression": "DASH = 2*abnormal_d_dimer + 1*(age<50) + 1*male + (-2)*hormone_use(female only); max 4; recurrence_band <=1 / 2 / >=3",
      "max_score": 4,
      "score": 0,
      "age_years": 60,
      "sex": "female",
      "recurrence_band": "<=1"
    },
    {
      "components": [
        {
          "factor": "abnormal_d_dimer",
          "points": 0,
          "present": false
        },
        {
          "value": 60,
          "factor": "age_lt_50",
          "points": 0,
          "present": false
        },
        {
          "factor": "male",
          "points": 0,
          "present": false
        },
        {
          "factor": "hormone_use",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Tosetto A, Iorio A, Marcucci M, et al.",
        "doi": "10.1111/j.1538-7836.2012.04735.x",
        "id": "tosetto-2012",
        "pmid": "22489957",
        "source": "J Thromb Haemost. 2012;10(6):1019-1025",
        "title": "Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH)"
      },
      "formula": "dash",
      "formula_expression": "DASH = 2*abnormal_d_dimer + 1*(age<50) + 1*male + (-2)*hormone_use(female only); max 4; recurrence_band <=1 / 2 / >=3",
      "max_score": 4,
      "score": 0,
      "age_years": 60,
      "sex": "female",
      "recurrence_band": "<=1"
    }
  ]
}
```

## Response fields

- `formula` (string): dash
- `formula_expression` (string): Exact expression used
- `score` (integer): DASH points from -2 to 4
- `max_score` (integer): 4
- `recurrence_band` (string): Tosetto 2012 published annualized-recurrence group: <=1, 2, or >=3. Percents are not returned. Not a stop-or-continue anticoagulation order.
- `age_years` (integer): Age used for the <50 criterion
- `sex` (string): female or male
- `components` (array): Per-factor points
- `citation` (object): Tosetto 2012 J Thromb Haemost citation
- `disclaimer` (string): Not-a-device notice

## Example JSON

Frozen fixture. Not a live lookup.

```json
{
  "components": [
    {
      "factor": "abnormal_d_dimer",
      "points": 0,
      "present": false
    },
    {
      "value": 60,
      "factor": "age_lt_50",
      "points": 0,
      "present": false
    },
    {
      "factor": "male",
      "points": 0,
      "present": false
    },
    {
      "factor": "hormone_use",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Tosetto A, Iorio A, Marcucci M, et al.",
    "doi": "10.1111/j.1538-7836.2012.04735.x",
    "id": "tosetto-2012",
    "pmid": "22489957",
    "source": "J Thromb Haemost. 2012;10(6):1019-1025",
    "title": "Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH)"
  },
  "formula": "dash",
  "formula_expression": "DASH = 2*abnormal_d_dimer + 1*(age<50) + 1*male + (-2)*hormone_use(female only); max 4; recurrence_band <=1 / 2 / >=3",
  "max_score": 4,
  "score": 0,
  "age_years": 60,
  "sex": "female",
  "recurrence_band": "<=1"
}
```

## Errors

- HTTP 400 `invalid_age`: age must be an integer from 18 to 120 Returned before settlement; you are not charged.
- HTTP 400 `invalid_sex`: sex must be female or male Returned before settlement; you are not charged.
- HTTP 400 `invalid_flag`: boolean clinical flags must be true or false Returned before settlement; you are not charged.
- HTTP 400 `invalid_dash_hormone`: hormone_use may be true only when sex is female (Tosetto 2012 DASH). Returned before settlement; you are not charged.
- HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
- HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
- HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged.

Shared HTTP 402 and 503: https://magentlab.com/docs/payments

## Related tools

- [Wells PE](https://magentlab.com/docs/wells-pe) — Compute the Wells pulmonary-embolism probability score and return three-tier and two-tier bands.
- [Wells DVT](https://magentlab.com/docs/wells-dvt) — Compute the Wells deep-vein thrombosis probability score and return three-tier and two-tier bands.
- [YEARS algorithm](https://magentlab.com/docs/years) — Apply the van der Hulle 2017 YEARS algorithm: count three caller-assigned items and return whether PE is excluded at the published D-dimer threshold.

## Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s.

- GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall).
- HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote.
- Sign accepts[0] (exact, EIP-3009) with validBefore = now + maxTimeoutSeconds (600 seconds), or accepts[1] (batch-settlement deposit/voucher) on product GET. Ping and POST {items} stay exact. Magent retries transient facilitator 429/5xx before answering.
- Retry the same URL with PAYMENT-SIGNATURE (base64 JSON echoing accepted, payload, and extensions when present).
- Success is HTTP 200 JSON plus PAYMENT-RESPONSE. exact settles before the tool. batch-settlement verifies (and deposit-settles) before the tool and commits the charge after HTTP 2xx. HTTP 503: retry the same PAYMENT-SIGNATURE. Mint a new exact nonce only after a new HTTP 402.

- offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront.
- offered `batch-settlement` on eip155:8453: Payment-channel vouchers claimed later in batches. Exact stays accepts[0]. Same-path POST {items} is still exact. extra.assetTransferMethod=eip3009 extra.paymentFlow=authorization.

- not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search.

Same-path POST {items} is still scheme exact: one EIP-3009 authorization for GET unit plus $0.002 per extra item. That is not x402 batch-settlement (payment channels / vouchers).

Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments

Stdio MCP (one process per host): https://magentlab.com/docs/mcp

## Guarantees

- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.
