# Ganzoni iron deficit

Ganzoni iron deficit

Status: LIVE
Price: $0.005 USDC
`GET /api/calc/ganzoni`
HTML: https://magentlab.com/docs/ganzoni
Markdown: https://magentlab.com/docs/ganzoni.md

Not a medical device. Not a diagnosis, dose, or listing recommendation.

## What it computes

Compute the Ganzoni 1970 iron deficit from weight, measured hemoglobin, a caller-supplied target hemoglobin, and depot iron stores.

## When to use

When an agent needs the published Ganzoni milligram deficit and must not invent a target hemoglobin, depot iron, or an IV iron product order.

## When not to use

- Not an IV iron product dose or order. magent does not pick target hemoglobin or depot iron.
- Not a diagnosis of iron deficiency.

## Formula

```
iron_deficit_mg = weight_kg * (target_hemoglobin_g_dl - hemoglobin_g_dl) * 2.4 + iron_stores_mg
```

## Citation

[Intravenous iron-dextran: therapeutic and experimental possibilities](https://pubmed.ncbi.nlm.nih.gov/5417430)
Ganzoni AM
Schweiz Med Wochenschr. 1970;100(7):301-303
DOI: none

## Worked example

### 70 kg, Hb 8 to 15 g/dL, stores 500 mg

Given: `hemoglobin_g_dl=8, iron_stores_mg=500, target_hemoglobin_g_dl=15, weight_kg=70`

1. iron_deficit = 70 * (15 - 8) * 2.4 + 500 = 1176 + 500 = 1676.0 mg


### 70 kg, Hb 8 to 15 g/dL, stores 0 mg

Given: `hemoglobin_g_dl=8, iron_stores_mg=0, target_hemoglobin_g_dl=15, weight_kg=70`

1. iron_deficit = 70 * (15 - 8) * 2.4 + 0 = 1176.0 mg


## Also searched as

- Ganzoni
- iron deficit
- iron deficit formula
- Ganzoni formula
- hemoglobin iron stores
- depot iron

## Parameters

- `weight_kg` (number, optional): Weight in kilograms. Provide weight_kg or weight_lb.
- `weight_lb` (number, optional): Weight in pounds. Converted as kg = lb * 0.45359237.
- `hemoglobin_g_dl` (number, required): Measured hemoglobin in g/dL (3-22). This tool does not accept g/L.
- `target_hemoglobin_g_dl` (number, required): Target hemoglobin in g/dL (7-18). Must be strictly greater than hemoglobin_g_dl. magent does not pick a target.
- `iron_stores_mg` (number, required): Depot iron stores in mg (0-2000). Required; magent does not default a depot.

## Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

Method: `POST /api/calc/ganzoni`
Max items: 25
Price: unit_amount + extra_item_amount * (n - 1) (unit 5000 atomic, extra 2000 atomic)
Status: PREVIEW

- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request:

```json
{
  "items": [
    {
      "hemoglobin_g_dl": "8",
      "iron_stores_mg": "500",
      "target_hemoglobin_g_dl": "15",
      "weight_kg": "70"
    },
    {
      "hemoglobin_g_dl": "8",
      "iron_stores_mg": "500",
      "target_hemoglobin_g_dl": "15",
      "weight_kg": "70"
    }
  ]
}
```

Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/ganzoni

Example 200:

```json
{
  "count": 2,
  "path": "/api/calc/ganzoni",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ganzoni AM",
        "id": "ganzoni-1970",
        "pmid": "5417430",
        "source": "Schweiz Med Wochenschr. 1970;100(7):301-303",
        "title": "Intravenous iron-dextran: therapeutic and experimental possibilities"
      },
      "formula": "ganzoni",
      "formula_expression": "iron_deficit_mg = weight_kg * (target_hemoglobin_g_dl - hemoglobin_g_dl) * 2.4 + iron_stores_mg",
      "weight_kg": 70.0,
      "hemoglobin_g_dl": 8.0,
      "iron_deficit_mg": 1676.0,
      "iron_stores_mg": 500.0,
      "target_hemoglobin_g_dl": 15.0
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ganzoni AM",
        "id": "ganzoni-1970",
        "pmid": "5417430",
        "source": "Schweiz Med Wochenschr. 1970;100(7):301-303",
        "title": "Intravenous iron-dextran: therapeutic and experimental possibilities"
      },
      "formula": "ganzoni",
      "formula_expression": "iron_deficit_mg = weight_kg * (target_hemoglobin_g_dl - hemoglobin_g_dl) * 2.4 + iron_stores_mg",
      "weight_kg": 70.0,
      "hemoglobin_g_dl": 8.0,
      "iron_deficit_mg": 1676.0,
      "iron_stores_mg": 500.0,
      "target_hemoglobin_g_dl": 15.0
    }
  ]
}
```

## Response fields

- `formula` (string): ganzoni
- `formula_expression` (string): Exact expression used
- `weight_kg` (number): Normalized weight in kg
- `hemoglobin_g_dl` (number): Measured hemoglobin in g/dL
- `target_hemoglobin_g_dl` (number): Target hemoglobin in g/dL used
- `iron_stores_mg` (number): Depot iron stores in mg used
- `iron_deficit_mg` (number): Iron deficit in mg, 1 decimal
- `citation` (object): Ganzoni 1970 citation
- `disclaimer` (string): Not-a-device notice

## Example JSON

Frozen fixture. Not a live lookup.

```json
{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Ganzoni AM",
    "id": "ganzoni-1970",
    "pmid": "5417430",
    "source": "Schweiz Med Wochenschr. 1970;100(7):301-303",
    "title": "Intravenous iron-dextran: therapeutic and experimental possibilities"
  },
  "formula": "ganzoni",
  "formula_expression": "iron_deficit_mg = weight_kg * (target_hemoglobin_g_dl - hemoglobin_g_dl) * 2.4 + iron_stores_mg",
  "weight_kg": 70.0,
  "hemoglobin_g_dl": 8.0,
  "iron_deficit_mg": 1676.0,
  "iron_stores_mg": 500.0,
  "target_hemoglobin_g_dl": 15.0
}
```

## Errors

- HTTP 400 `invalid_weight`: weight_kg (1-500) or weight_lb (2-1100) is required Returned before settlement; you are not charged.
- HTTP 400 `invalid_hemoglobin`: hemoglobin_g_l (30-220) or hemoglobin_g_dl (3-22) is required, not both. Returned before settlement; you are not charged.
- HTTP 400 `invalid_target_hemoglobin`: target_hemoglobin_g_dl must be 7-18 and strictly greater than hemoglobin_g_dl. Returned before settlement; you are not charged.
- HTTP 400 `invalid_iron_stores`: iron_stores_mg must be a number from 0 to 2000. Returned before settlement; you are not charged.
- HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
- HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
- HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged.

Shared HTTP 402 and 503: https://magentlab.com/docs/payments

## Related tools

- [ANC](https://magentlab.com/docs/anc) — Compute absolute neutrophil count from WBC and neutrophil plus band percents, plus a Bodey 1966 granulocyte band.
- [Devine IBW](https://magentlab.com/docs/ibw) — Compute Devine ideal body weight and 0.4 adjusted body weight from height, sex, and actual weight.

## Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s.

- GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall).
- HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote.
- Sign accepts[0] (exact, EIP-3009) with validBefore = now + maxTimeoutSeconds (600 seconds), or accepts[1] (batch-settlement deposit/voucher) on product GET. Ping and POST {items} stay exact. Magent retries transient facilitator 429/5xx before answering.
- Retry the same URL with PAYMENT-SIGNATURE (base64 JSON echoing accepted, payload, and extensions when present).
- Success is HTTP 200 JSON plus PAYMENT-RESPONSE. exact settles before the tool. batch-settlement verifies (and deposit-settles) before the tool and commits the charge after HTTP 2xx. HTTP 503: retry the same PAYMENT-SIGNATURE. Mint a new exact nonce only after a new HTTP 402.

- offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront.
- offered `batch-settlement` on eip155:8453: Payment-channel vouchers claimed later in batches. Exact stays accepts[0]. Same-path POST {items} is still exact. extra.assetTransferMethod=eip3009 extra.paymentFlow=authorization.

- not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search.

Same-path POST {items} is still scheme exact: one EIP-3009 authorization for GET unit plus $0.002 per extra item. That is not x402 batch-settlement (payment channels / vouchers).

Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments

Stdio MCP (one process per host): https://magentlab.com/docs/mcp

## Guarantees

- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.
