# Neonatal glucose infusion rate

Neonatal glucose infusion rate

Status: LIVE
Price: $0.005 USDC
`GET /api/calc/gir`
HTML: https://magentlab.com/docs/gir
Markdown: https://magentlab.com/docs/gir.md

Not a medical device. Not a diagnosis, dose, or listing recommendation.

## What it computes

Compute neonatal glucose infusion rate in mg/kg/min from dextrose concentration and infusion rate using the unit conversion used with the 2011 AAP postnatal glucose homeostasis report.

## When to use

When an agent already has dextrose percent and either ml/h plus weight or ml/kg/h and must not order dextrose, TPN, or treat GIR as a glucose prescription.

## When not to use

- Not a medical device. Not a glucose or TPN prescription. magent does not order dextrose.
- GIR = (dextrose_percent × rate_ml_h) / (6 × weight_kg), or (dextrose_percent × rate_ml_kg_h) / 6. Provide rate_ml_h with weight_kg, or rate_ml_kg_h, not both rate styles.
- dextrose_percent 2.5-25, weight_kg 0.4-10, rate_ml_h 0.5-200, and rate_ml_kg_h 0.5-20 are magent clamps; they are not AAP 2011 input bands.
- AAP 2011 describes intravenous D10W at 5 to 8 mg/kg per minute (80 to 100 mL/kg per day) for persistent hypoglycemia. magent reports gir_mg_kg_min only and does not classify that treatment range or order fluids.
- Caller supplies dextrose concentration and infusion rate. magent does not assay plasma glucose.

## Formula

```
gir_mg_kg_min = (dextrose_percent × rate_ml_h) / (6 × weight_kg); equivalently (dextrose_percent × rate_ml_kg_h) / 6
```

## Citation

[Postnatal glucose homeostasis in late-preterm and term infants](https://doi.org/10.1542/peds.2010-3851)
Adamkin DH; Committee on Fetus and Newborn, American Academy of Pediatrics
Pediatrics. 2011;127(3):575-579
DOI: [10.1542/peds.2010-3851](https://doi.org/10.1542/peds.2010-3851)

## Worked example

### D10W 7.5 ml/h, weight 3 kg

Given: `dextrose_percent=10, rate_ml_h=7.5, weight_kg=3`

1. gir_mg_kg_min = (10 × 7.5) / (6 × 3) = 75 / 18 = 4.2


### D10W 2.5 ml/kg/h

Given: `dextrose_percent=10, rate_ml_kg_h=2.5`

1. gir_mg_kg_min = (10 × 2.5) / 6 = 25 / 6 = 4.2


## Also searched as

- glucose infusion rate
- GIR
- neonatal GIR
- GIR mg/kg/min
- dextrose infusion rate
- neonatal glucose infusion
- IV glucose infusion rate
- D10W GIR

## Parameters

- `dextrose_percent` (number, required): Dextrose concentration as percent (2.5-25, magent clamp; AAP 2011 does not publish an input band). 10 is D10W. magent does not order dextrose.
- `rate_ml_h` (number, optional): Infusion rate in ml/h (0.5-200, magent clamp; AAP 2011 does not publish an input band). Provide this with weight_kg, or provide rate_ml_kg_h, not both rate styles.
- `weight_kg` (number, optional): Weight in kg (0.4-10, magent clamp; AAP 2011 does not publish an input band). Required with rate_ml_h. Not required when rate_ml_kg_h is the only rate. magent does not weigh the infant.
- `rate_ml_kg_h` (number, optional): Infusion rate in ml/kg/h (0.5-20, magent clamp). GIR = (dextrose_percent × rate_ml_kg_h) / 6. Provide this or rate_ml_h plus weight_kg, not both rate styles.

## Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

Method: `POST /api/calc/gir`
Max items: 25
Price: unit_amount + extra_item_amount * (n - 1) (unit 5000 atomic, extra 2000 atomic)
Status: PREVIEW

- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request:

```json
{
  "items": [
    {
      "dextrose_percent": "10",
      "rate_ml_h": "7.5",
      "weight_kg": "3"
    },
    {
      "dextrose_percent": "10",
      "rate_ml_h": "7.5",
      "weight_kg": "3"
    }
  ]
}
```

Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/gir

Example 200:

```json
{
  "count": 2,
  "path": "/api/calc/gir",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Adamkin DH; Committee on Fetus and Newborn, American Academy of Pediatrics",
        "doi": "10.1542/peds.2010-3851",
        "id": "aap-2011-glucose",
        "pmid": "21357346",
        "source": "Pediatrics. 2011;127(3):575-579",
        "title": "Postnatal glucose homeostasis in late-preterm and term infants"
      },
      "formula": "gir",
      "formula_expression": "gir_mg_kg_min = (dextrose_percent × rate_ml_h) / (6 × weight_kg); equivalently (dextrose_percent × rate_ml_kg_h) / 6",
      "weight_kg": 3.0,
      "dextrose_percent": 10.0,
      "gir_mg_kg_min": 4.2,
      "rate_ml_h": 7.5,
      "rate_ml_kg_h": 2.5
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Adamkin DH; Committee on Fetus and Newborn, American Academy of Pediatrics",
        "doi": "10.1542/peds.2010-3851",
        "id": "aap-2011-glucose",
        "pmid": "21357346",
        "source": "Pediatrics. 2011;127(3):575-579",
        "title": "Postnatal glucose homeostasis in late-preterm and term infants"
      },
      "formula": "gir",
      "formula_expression": "gir_mg_kg_min = (dextrose_percent × rate_ml_h) / (6 × weight_kg); equivalently (dextrose_percent × rate_ml_kg_h) / 6",
      "weight_kg": 3.0,
      "dextrose_percent": 10.0,
      "gir_mg_kg_min": 4.2,
      "rate_ml_h": 7.5,
      "rate_ml_kg_h": 2.5
    }
  ]
}
```

## Response fields

- `formula` (string): gir
- `formula_expression` (string): Exact expression used
- `dextrose_percent` (number): Dextrose concentration used, percent
- `rate_ml_h` (number): Infusion rate in ml/h when that rate style is supplied
- `weight_kg` (number): Weight in kg when rate_ml_h is used
- `rate_ml_kg_h` (number): Infusion rate in ml/kg/h (supplied, or rate_ml_h / weight_kg)
- `gir_mg_kg_min` (number): Glucose infusion rate in mg/kg/min, 1 decimal
- `citation` (object): AAP 2011 postnatal glucose citation
- `disclaimer` (string): Not-a-device notice

## Example JSON

Frozen fixture. Not a live lookup.

```json
{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Adamkin DH; Committee on Fetus and Newborn, American Academy of Pediatrics",
    "doi": "10.1542/peds.2010-3851",
    "id": "aap-2011-glucose",
    "pmid": "21357346",
    "source": "Pediatrics. 2011;127(3):575-579",
    "title": "Postnatal glucose homeostasis in late-preterm and term infants"
  },
  "formula": "gir",
  "formula_expression": "gir_mg_kg_min = (dextrose_percent × rate_ml_h) / (6 × weight_kg); equivalently (dextrose_percent × rate_ml_kg_h) / 6",
  "weight_kg": 3.0,
  "dextrose_percent": 10.0,
  "gir_mg_kg_min": 4.2,
  "rate_ml_h": 7.5,
  "rate_ml_kg_h": 2.5
}
```

## Errors

- HTTP 400 `invalid_gir`: GIR needs dextrose percent and either rate_ml_h plus weight_kg, or rate_ml_kg_h, as used for neonatal glucose infusion (mg/kg/min). Returned before settlement; you are not charged.
- HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
- HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
- HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged.

Shared HTTP 402 and 503: https://magentlab.com/docs/payments

## Related tools

- [Apgar score](https://magentlab.com/docs/apgar) — Compute the Apgar newborn evaluation score as the sum of five caller-assigned 0-2 signs.
- [Rebound hyperbilirubinemia](https://magentlab.com/docs/rebound-hyperbilirubinemia) — Return the Chang 2017 three-variable rebound hyperbilirubinemia prediction score after inpatient phototherapy from gestational age, age at phototherapy initiation in days, TSB at termination, and a caller-supplied AAP phototherapy threshold. Scores <20 correspond to a <4% probability of rebound in that paper.

## Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s.

- GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall).
- HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote.
- Sign accepts[0] (exact, EIP-3009) with validBefore = now + maxTimeoutSeconds (600 seconds), or accepts[1] (batch-settlement deposit/voucher) on product GET. Ping and POST {items} stay exact. Magent retries transient facilitator 429/5xx before answering.
- Retry the same URL with PAYMENT-SIGNATURE (base64 JSON of accepted and payload). Magent attaches canonical extensions.bazaar on CDP verify/settle; echoing 402 bazaar is optional.
- Success is HTTP 200 JSON plus PAYMENT-RESPONSE. exact settles before the tool. batch-settlement verifies (and deposit-settles) before the tool and commits the charge after HTTP 2xx. HTTP 503: retry the same PAYMENT-SIGNATURE. Mint a new exact nonce only after a new HTTP 402.

- offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront.
- offered `batch-settlement` on eip155:8453: Payment-channel vouchers claimed later in batches. Exact stays accepts[0]. Same-path POST {items} is still exact. extra.assetTransferMethod=eip3009 extra.paymentFlow=authorization.

- not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search.

Same-path POST {items} is still scheme exact: one EIP-3009 authorization for GET unit plus $0.002 per extra item. That is not x402 batch-settlement (payment channels / vouchers).

Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments

Stdio MCP (one process per host): https://magentlab.com/docs/mcp

## Guarantees

- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.