# Plasma starting dose Plasma starting dose Status: LIVE Price: $0.005 USDC `GET /api/calc/plasma_dosage` HTML: https://magentlab.com/docs/plasma-dosage Markdown: https://magentlab.com/docs/plasma-dosage.md Not a medical device. Not a diagnosis, dose, or listing recommendation. ## What it computes Compute the BSH Green 2018 starting plasma volume from body weight: 15 mL/kg in the absence of major bleeding. Adult starting dose only. ## When to use When an agent needs the published adult starting plasma volume and must not invent a major-haemorrhage RBC:plasma ratio, a cryoprecipitate pool, a paediatric variant, or a product or ABO-group choice. ## When not to use - Not a medical device. Not a transfusion order. - Not a major-haemorrhage protocol. Does not implement RBC:plasma ratios, cryoprecipitate pools, or paediatric variants. Adult starting 15 mL/kg only. - magent does not choose a product or ABO group. ## Formula ``` volume_ml = 15 * weight_kg ``` ## Citation [Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding](https://doi.org/10.1111/bjh.15167) Green L, Bolton-Maggs P, Beattie C, Cardigan R, Kallis Y, Stanworth SJ, Thachil J, Zahra S; British Society for Haematology Br J Haematol. 2018;181(1):54-67 DOI: [10.1111/bjh.15167](https://doi.org/10.1111/bjh.15167) ## Worked example ### 70 kg adult starting plasma volume Given: `weight_kg=70` 1. volume_ml = 15 * 70 = 1050.0 ### 10 kg starting plasma volume Given: `weight_kg=10` 1. volume_ml = 15 * 10 = 150.0 ## Also searched as - plasma starting dose - plasma 15 ml per kg - BSH plasma volume - Green 2018 plasma - adult plasma starting volume - plasma dosage - starting plasma volume ## Parameters - `weight_kg` (number, required): Weight in kilograms (1-500). Required. ## Bulk (POST) POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement. Method: `POST /api/calc/plasma_dosage` Max items: 25 Price: unit_amount + extra_item_amount * (n - 1) (unit 5000 atomic, extra 2000 atomic) Status: PREVIEW - 1 to 25 items. Each item uses the same keys as the GET query parameters. - POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows. - The first invalid item fails the whole request (index in the 400 JSON). You are not charged. - HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row. - Catalog misses (empty matches, found=false) stay paid 200s inside that slot. - x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items. Example request: ```json { "items": [ { "weight_kg": "70" }, { "weight_kg": "70" } ] } ``` Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/plasma-dosage Example 200: ```json { "count": 2, "path": "/api/calc/plasma_dosage", "items": [ { "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "citation": { "authors": "Green L, Bolton-Maggs P, Beattie C, Cardigan R, Kallis Y, Stanworth SJ, Thachil J, Zahra S; British Society for Haematology", "doi": "10.1111/bjh.15167", "id": "green-2018", "pmid": "29524364", "source": "Br J Haematol. 2018;181(1):54-67", "title": "Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding" }, "formula": "plasma_dosage", "formula_expression": "volume_ml = 15 * weight_kg", "volume_ml": 1050.0, "weight_kg": 70.0, "ml_per_kg": 15 }, { "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "citation": { "authors": "Green L, Bolton-Maggs P, Beattie C, Cardigan R, Kallis Y, Stanworth SJ, Thachil J, Zahra S; British Society for Haematology", "doi": "10.1111/bjh.15167", "id": "green-2018", "pmid": "29524364", "source": "Br J Haematol. 2018;181(1):54-67", "title": "Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding" }, "formula": "plasma_dosage", "formula_expression": "volume_ml = 15 * weight_kg", "volume_ml": 1050.0, "weight_kg": 70.0, "ml_per_kg": 15 } ] } ``` ## Response fields - `formula` (string): plasma_dosage - `formula_expression` (string): Exact expression used - `weight_kg` (number): Input weight in kg - `ml_per_kg` (number): BSH Green 2018 starting plasma millilitres per kilogram (15) - `volume_ml` (number): Starting plasma volume in mL, 1 decimal - `citation` (object): Green et al. BSH 2018 citation - `disclaimer` (string): Not-a-device notice ## Example JSON Frozen fixture. Not a live lookup. ```json { "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "citation": { "authors": "Green L, Bolton-Maggs P, Beattie C, Cardigan R, Kallis Y, Stanworth SJ, Thachil J, Zahra S; British Society for Haematology", "doi": "10.1111/bjh.15167", "id": "green-2018", "pmid": "29524364", "source": "Br J Haematol. 2018;181(1):54-67", "title": "Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding" }, "formula": "plasma_dosage", "formula_expression": "volume_ml = 15 * weight_kg", "volume_ml": 1050.0, "weight_kg": 70.0, "ml_per_kg": 15 } ``` ## Errors - HTTP 400 `invalid_plasma`: Plasma volume inputs must match Green 2018 BSH weight from that guideline. Returned before settlement; you are not charged. - HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged. - HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged. - HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged. Shared HTTP 402 and 503: https://magentlab.com/docs/payments ## Related tools - [Allowable blood loss](https://magentlab.com/docs/allowable-blood-loss) — Compute Gross 1983 dilution-corrected allowable blood loss from a caller-supplied estimated blood volume and initial versus target hematocrit. - [Kaplan plasma volume](https://magentlab.com/docs/tpe) — Compute Kaplan 1990 estimated plasma volume for therapeutic plasma exchange from weight and hematocrit as a percent, returning one plasma volume in liters and milliliters. - [Ganzoni iron deficit](https://magentlab.com/docs/ganzoni) — Compute the Ganzoni 1970 iron deficit from weight, measured hemoglobin, a caller-supplied target hemoglobin, and depot iron stores. ## Payment Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. - GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall). - HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote. - Sign accepts[0] (exact, EIP-3009) with validBefore = now + maxTimeoutSeconds (600 seconds), or accepts[1] (batch-settlement deposit/voucher) on product GET. Ping and POST {items} stay exact. Magent retries transient facilitator 429/5xx before answering. - Retry the same URL with PAYMENT-SIGNATURE (base64 JSON of accepted and payload). Magent attaches canonical extensions.bazaar on CDP verify/settle; echoing 402 bazaar is optional. - Success is HTTP 200 JSON plus PAYMENT-RESPONSE. exact settles before the tool. batch-settlement verifies (and deposit-settles) before the tool and commits the charge after HTTP 2xx. HTTP 503: retry the same PAYMENT-SIGNATURE. Mint a new exact nonce only after a new HTTP 402. - offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront. - offered `batch-settlement` on eip155:8453: Payment-channel vouchers claimed later in batches. Exact stays accepts[0]. Same-path POST {items} is still exact. extra.assetTransferMethod=eip3009 extra.paymentFlow=authorization. - not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search. Same-path POST {items} is still scheme exact: one EIP-3009 authorization for GET unit plus $0.002 per extra item. That is not x402 batch-settlement (payment channels / vouchers). Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments Stdio MCP (one process per host): https://magentlab.com/docs/mcp ## Guarantees - HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON. - exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE. - HTTP 402 is unpaid only. Do not sign a second authorization because of a 503. - Execution is timeout-bounded and concurrency-capped. - Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.