# RIETE major bleeding score

RIETE

Status: LIVE
Price: $0.005 USDC
`GET /api/calc/riete`
HTML: https://magentlab.com/docs/riete
Markdown: https://magentlab.com/docs/riete.md

Not a medical device. Not a diagnosis, dose, or listing recommendation.

## What it computes

Sum the Ruiz-Giménez 2008 RIETE adverse factors for 3-month major bleeding after documented acute VTE and return low (0), intermediate (1–4), or high (>4).

## When to use

When an agent needs the published RIETE 2008 point total and class and must not invent a VTE diagnosis or a bleed-treatment or anticoagulation protocol.

## When not to use

- Not a medical device and not a VTE diagnosis or bleed-treatment protocol. magent does not examine the patient.
- Bands are published 3-month major-bleed rates from Ruiz-Giménez 2008 (derivation 0.3%/2.6%/7.3%; validation 0.1%/2.8%/6.2%), not an anticoagulation protocol.
- magent does not assay hemoglobin or compute creatinine from a lab. All six inputs are caller-assigned flags. Anemia in the paper is Hb <13 g/dL in men / <12 g/dL in women.

## Formula

```
RIETE = recent_major_bleeding 2.0 + creatinine_gt_1_2 1.5 + anemia 1.5 + cancer 1.0 + clinically_overt_pe 1.0 + age_gt_75 1.0; Ruiz-Giménez 2008; max 8; low 0, intermediate 1-4, high >4
```

## Citation

[Predictive variables for major bleeding events in patients presenting with documented acute venous thromboembolism. Findings from the RIETE Registry](https://doi.org/10.1160/TH08-03-0193)
Ruiz-Giménez N, Suárez C, González R, Nieto JA, Todolí JA, Samperiz AL, Monreal M; RIETE Investigators
Thromb Haemost. 2008;100(1):26-31
DOI: [10.1160/TH08-03-0193](https://doi.org/10.1160/TH08-03-0193)

## Worked example

### All flags false

Given: `age_gt_75=false, anemia=false, cancer=false, clinically_overt_pe=false, creatinine_gt_1_2=false, recent_major_bleeding=false`

1. All six caller-assigned flags false → 0
2. Score = 0 (max 8); riete_band = low


### Recent major bleeding, creatinine >1.2 mg/dL, and anemia

Given: `age_gt_75=false, anemia=true, cancer=false, clinically_overt_pe=false, creatinine_gt_1_2=true, recent_major_bleeding=true`

1. recent_major_bleeding → 2.0; creatinine_gt_1_2 → 1.5; anemia → 1.5; remaining flags 0
2. Score = 5.0 (max 8); riete_band = high (>4)


## Also searched as

- RIETE score
- RIETE bleeding score
- Ruiz-Giménez RIETE
- VTE major bleeding score
- RIETE Registry bleeding
- acute VTE bleed risk

## Parameters

- `recent_major_bleeding` (boolean, required): Recent major bleeding as assigned by the caller (Ruiz-Giménez 2008). true scores 2.0. magent does not grade bleeding.
- `creatinine_gt_1_2` (boolean, required): Creatinine >1.2 mg/dL as assigned by the caller (Ruiz-Giménez 2008). true scores 1.5. magent does not compute creatinine from a lab.
- `anemia` (boolean, required): Anemia as assigned by the caller (Ruiz-Giménez 2008: hemoglobin <13 g/dL in men or <12 g/dL in women). true scores 1.5. magent does not assay hemoglobin.
- `cancer` (boolean, required): Cancer as assigned by the caller (Ruiz-Giménez 2008). true scores 1.0. magent does not diagnose cancer.
- `clinically_overt_pe` (boolean, required): Clinically overt pulmonary embolism as assigned by the caller (Ruiz-Giménez 2008). true scores 1.0. magent does not diagnose PE.
- `age_gt_75` (boolean, required): Age >75 years as assigned by the caller (Ruiz-Giménez 2008). true scores 1.0. magent does not assign age.

## Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

Method: `POST /api/calc/riete`
Max items: 25
Price: unit_amount + extra_item_amount * (n - 1) (unit 5000 atomic, extra 2000 atomic)
Status: PREVIEW

- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request:

```json
{
  "items": [
    {
      "age_gt_75": "false",
      "anemia": "false",
      "cancer": "false",
      "clinically_overt_pe": "false",
      "creatinine_gt_1_2": "false",
      "recent_major_bleeding": "false"
    },
    {
      "age_gt_75": "false",
      "anemia": "false",
      "cancer": "false",
      "clinically_overt_pe": "false",
      "creatinine_gt_1_2": "false",
      "recent_major_bleeding": "false"
    }
  ]
}
```

Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/riete

Example 200:

```json
{
  "count": 2,
  "path": "/api/calc/riete",
  "items": [
    {
      "components": [
        {
          "factor": "recent_major_bleeding",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "creatinine_gt_1_2",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "anemia",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "cancer",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "clinically_overt_pe",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "age_gt_75",
          "points": 0.0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ruiz-Giménez N, Suárez C, González R, Nieto JA, Todolí JA, Samperiz AL, Monreal M; RIETE Investigators",
        "doi": "10.1160/TH08-03-0193",
        "id": "ruiz-gimenez-2008",
        "pmid": "18612548",
        "source": "Thromb Haemost. 2008;100(1):26-31",
        "title": "Predictive variables for major bleeding events in patients presenting with documented acute venous thromboembolism. Findings from the RIETE Registry"
      },
      "formula": "riete",
      "formula_expression": "RIETE = recent_major_bleeding 2.0 + creatinine_gt_1_2 1.5 + anemia 1.5 + cancer 1.0 + clinically_overt_pe 1.0 + age_gt_75 1.0; Ruiz-Giménez 2008; max 8; low 0, intermediate 1-4, high >4",
      "max_score": 8,
      "score": 0.0,
      "riete_band": "low"
    },
    {
      "components": [
        {
          "factor": "recent_major_bleeding",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "creatinine_gt_1_2",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "anemia",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "cancer",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "clinically_overt_pe",
          "points": 0.0,
          "present": false
        },
        {
          "factor": "age_gt_75",
          "points": 0.0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ruiz-Giménez N, Suárez C, González R, Nieto JA, Todolí JA, Samperiz AL, Monreal M; RIETE Investigators",
        "doi": "10.1160/TH08-03-0193",
        "id": "ruiz-gimenez-2008",
        "pmid": "18612548",
        "source": "Thromb Haemost. 2008;100(1):26-31",
        "title": "Predictive variables for major bleeding events in patients presenting with documented acute venous thromboembolism. Findings from the RIETE Registry"
      },
      "formula": "riete",
      "formula_expression": "RIETE = recent_major_bleeding 2.0 + creatinine_gt_1_2 1.5 + anemia 1.5 + cancer 1.0 + clinically_overt_pe 1.0 + age_gt_75 1.0; Ruiz-Giménez 2008; max 8; low 0, intermediate 1-4, high >4",
      "max_score": 8,
      "score": 0.0,
      "riete_band": "low"
    }
  ]
}
```

## Response fields

- `formula` (string): riete
- `formula_expression` (string): Exact expression used
- `score` (number): RIETE points 0-8 (0.5 steps; not rounded)
- `max_score` (integer): Always 8
- `riete_band` (string): low when score is 0, intermediate when 1-4 inclusive, high when >4 (Ruiz-Giménez 2008 derivation 3-month major bleed 0.3%/2.6%/7.3%). Not a VTE diagnosis or bleed-treatment protocol.
- `components` (array): Per-factor points
- `citation` (object): Ruiz-Giménez 2008 Thromb Haemost citation
- `disclaimer` (string): Not-a-device notice

## Example JSON

Frozen fixture. Not a live lookup.

```json
{
  "components": [
    {
      "factor": "recent_major_bleeding",
      "points": 0.0,
      "present": false
    },
    {
      "factor": "creatinine_gt_1_2",
      "points": 0.0,
      "present": false
    },
    {
      "factor": "anemia",
      "points": 0.0,
      "present": false
    },
    {
      "factor": "cancer",
      "points": 0.0,
      "present": false
    },
    {
      "factor": "clinically_overt_pe",
      "points": 0.0,
      "present": false
    },
    {
      "factor": "age_gt_75",
      "points": 0.0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Ruiz-Giménez N, Suárez C, González R, Nieto JA, Todolí JA, Samperiz AL, Monreal M; RIETE Investigators",
    "doi": "10.1160/TH08-03-0193",
    "id": "ruiz-gimenez-2008",
    "pmid": "18612548",
    "source": "Thromb Haemost. 2008;100(1):26-31",
    "title": "Predictive variables for major bleeding events in patients presenting with documented acute venous thromboembolism. Findings from the RIETE Registry"
  },
  "formula": "riete",
  "formula_expression": "RIETE = recent_major_bleeding 2.0 + creatinine_gt_1_2 1.5 + anemia 1.5 + cancer 1.0 + clinically_overt_pe 1.0 + age_gt_75 1.0; Ruiz-Giménez 2008; max 8; low 0, intermediate 1-4, high >4",
  "max_score": 8,
  "score": 0.0,
  "riete_band": "low"
}
```

## Errors

- HTTP 400 `invalid_flag`: boolean clinical flags must be true or false Returned before settlement; you are not charged.
- HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
- HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
- HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged.

Shared HTTP 402 and 503: https://magentlab.com/docs/payments

## Related tools

- [Wells PE](https://magentlab.com/docs/wells-pe) — Compute the Wells pulmonary-embolism probability score and return three-tier and two-tier bands.
- [Hestia criteria](https://magentlab.com/docs/hestia) — Apply the Zondag 2011 Hestia exclusion checklist and return whether outpatient treatment of acute PE is eligible from 11 caller-assigned items.
- [Padua score](https://magentlab.com/docs/padua) — Compute the Barbar 2010 Padua Prediction Score for VTE risk in hospitalized medical patients from age and ten caller-assigned findings.

## Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s.

- GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall).
- HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote.
- Sign accepts[0] (exact, EIP-3009) with validBefore = now + maxTimeoutSeconds (600 seconds), or accepts[1] (batch-settlement deposit/voucher) on product GET. Ping and POST {items} stay exact. Magent retries transient facilitator 429/5xx before answering.
- Retry the same URL with PAYMENT-SIGNATURE (base64 JSON of accepted and payload). Magent attaches canonical extensions.bazaar on CDP verify/settle; echoing 402 bazaar is optional.
- Success is HTTP 200 JSON plus PAYMENT-RESPONSE. exact settles before the tool. batch-settlement verifies (and deposit-settles) before the tool and commits the charge after HTTP 2xx. HTTP 503: retry the same PAYMENT-SIGNATURE. Mint a new exact nonce only after a new HTTP 402.

- offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront.
- offered `batch-settlement` on eip155:8453: Payment-channel vouchers claimed later in batches. Exact stays accepts[0]. Same-path POST {items} is still exact. extra.assetTransferMethod=eip3009 extra.paymentFlow=authorization.

- not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search.

Same-path POST {items} is still scheme exact: one EIP-3009 authorization for GET unit plus $0.002 per extra item. That is not x402 batch-settlement (payment channels / vouchers).

Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments

Stdio MCP (one process per host): https://magentlab.com/docs/mcp

## Guarantees

- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.
