# SIRS SIRS Status: LIVE Price: $0.005 USDC `GET /api/calc/sirs` HTML: https://magentlab.com/docs/sirs Markdown: https://magentlab.com/docs/sirs.md Not a medical device. Not a diagnosis, dose, or listing recommendation. ## What it computes Compute the Bone 1992 ACCP/SCCM SIRS criteria from temperature, heart rate, respiratory rate, and WBC, with optional PaCO2 and band percent. ## When to use When an agent needs the published 1992 SIRS definition and must not substitute Sepsis-3, qSOFA, or SOFA, or treat the result as a diagnosis of sepsis. ## When not to use - Not a diagnosis of sepsis, severe sepsis, or septic shock. magent does not require a suspected-infection flag. - This is Bone 1992 ACCP/SCCM SIRS only. It is not Sepsis-3, not qSOFA, and not SOFA. - Thresholds are strict inequalities as published: temperature >38 or <36 °C, heart rate >90, respiratory rate >20 or PaCO2 <32 mm Hg, WBC >12000 or <4000/µL or bands >10%. - PaCO2 and band percent are optional. Omitted PaCO2 uses respiratory rate only; omitted bands uses WBC only. ## Formula ``` SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4 ``` ## Citation [Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis](https://doi.org/10.1378/chest.101.6.1644) Bone RC, Balk RA, Cerra FB, et al. Chest. 1992;101(6):1644-1655 DOI: [10.1378/chest.101.6.1644](https://doi.org/10.1378/chest.101.6.1644) ## Worked example ### No criteria met Given: `heart_rate_bpm=80, respiratory_rate=16, temperature_c=37.0, wbc_ul=8000` 1. Temperature 37.0 is not >38 or <36; HR 80 is not >90; RR 16 is not >20; WBC 8000 is not >12000 or <4000 2. sirs_criteria_met = 0; sirs_present = false (need ≥2 of 4) ### Two criteria met Given: `heart_rate_bpm=91, respiratory_rate=21, temperature_c=37.0, wbc_ul=8000` 1. HR 91 > 90 → 1; RR 21 > 20 → 1; temperature and WBC do not meet 2. sirs_criteria_met = 2; sirs_present = true ## Also searched as - SIRS criteria - systemic inflammatory response syndrome - Bone 1992 SIRS - ACCP SCCM SIRS - SIRS score - SIRS definition ## Parameters - `temperature_c` (number, required): Temperature in °C (30.0-45.0). >38 or <36 scores 1 (38.0 and 36.0 do not). - `heart_rate_bpm` (integer, required): Heart rate in beats/min (integer 30-220). >90 scores 1 (90 does not). - `respiratory_rate` (integer, required): Respiratory rate in breaths/min (integer 4-80). >20 scores 1 for the respiratory criterion (20 does not). Optional paco2_mm_hg <32 also meets this criterion. - `paco2_mm_hg` (number, optional): Arterial PaCO2 in mm Hg (8-80) when provided. Omitted uses respiratory rate only. <32 scores the respiratory criterion (32 does not). - `wbc_k_ul` (number, optional): WBC in 10^3/µL (same as 10^9/L). Provide wbc_k_ul or wbc_ul. Range 0.01-500. >12000 or <4000 per µL scores 1. - `wbc_ul` (number, optional): WBC in cells/µL (same as cells/mm^3). Provide wbc_k_ul or wbc_ul. Range 10-500000. >12000 or <4000 scores 1 (12000 and 4000 do not). - `band_percent` (number, optional): Immature bands as a percent of WBC (0-100) when provided. Omitted does not use bands. >10 scores the WBC criterion (10 does not). ## Bulk (POST) POST the same path with a JSON items array. Price is n times the GET unit. Invalid items return HTTP 400 before settlement. Method: `POST /api/calc/sirs` Max items: 25 Price: unit_amount * n (unit 5000 atomic) Status: PREVIEW - 1 to 25 items. Each item uses the same keys as the GET query parameters. - The first invalid item fails the whole request (index in the 400 JSON). You are not charged. - HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row. - Catalog misses (empty matches, found=false) stay paid 200s inside that slot. - x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items. Example request: ```json { "items": [ { "heart_rate_bpm": "80", "respiratory_rate": "16", "temperature_c": "37.0", "wbc_ul": "8000" }, { "heart_rate_bpm": "80", "respiratory_rate": "16", "temperature_c": "37.0", "wbc_ul": "8000" } ] } ``` Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/sirs Example 200: ```json { "count": 2, "path": "/api/calc/sirs", "items": [ { "components": [ { "value": 37.0, "factor": "temperature", "points": 0, "present": false }, { "value": 80, "factor": "heart_rate_gt_90", "points": 0, "present": false }, { "value": 16, "factor": "respiratory", "points": 0, "present": false }, { "value": 8.0e3, "factor": "wbc", "points": 0, "present": false } ], "wbc_per_ul": 8.0e3, "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "citation": { "authors": "Bone RC, Balk RA, Cerra FB, et al.", "doi": "10.1378/chest.101.6.1644", "id": "bone-1992", "source": "Chest. 1992;101(6):1644-1655", "title": "Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis" }, "formula": "sirs", "formula_expression": "SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4", "max_score": 4, "temperature_c": 37.0, "heart_rate_bpm": 80, "respiratory_rate": 16, "sirs_criteria_met": 0, "sirs_present": false }, { "components": [ { "value": 37.0, "factor": "temperature", "points": 0, "present": false }, { "value": 80, "factor": "heart_rate_gt_90", "points": 0, "present": false }, { "value": 16, "factor": "respiratory", "points": 0, "present": false }, { "value": 8.0e3, "factor": "wbc", "points": 0, "present": false } ], "wbc_per_ul": 8.0e3, "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "citation": { "authors": "Bone RC, Balk RA, Cerra FB, et al.", "doi": "10.1378/chest.101.6.1644", "id": "bone-1992", "source": "Chest. 1992;101(6):1644-1655", "title": "Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis" }, "formula": "sirs", "formula_expression": "SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4", "max_score": 4, "temperature_c": 37.0, "heart_rate_bpm": 80, "respiratory_rate": 16, "sirs_criteria_met": 0, "sirs_present": false } ] } ``` ## Response fields - `formula` (string): sirs - `formula_expression` (string): Exact expression used - `sirs_present` (boolean): true when sirs_criteria_met is ≥2. Not a diagnosis of sepsis. - `sirs_criteria_met` (integer): Count of Bone 1992 criteria met (0-4) - `max_score` (integer): Always 4 - `temperature_c` (number): Temperature in °C used - `heart_rate_bpm` (integer): Heart rate used, bpm - `respiratory_rate` (integer): Respiratory rate used, breaths/min - `wbc_per_ul` (number): Normalized WBC in cells/µL used for scoring - `components` (array): Per-criterion points - `citation` (object): Bone 1992 Chest citation - `disclaimer` (string): Not-a-device notice ## Example JSON Frozen fixture. Not a live lookup. ```json { "components": [ { "value": 37.0, "factor": "temperature", "points": 0, "present": false }, { "value": 80, "factor": "heart_rate_gt_90", "points": 0, "present": false }, { "value": 16, "factor": "respiratory", "points": 0, "present": false }, { "value": 8.0e3, "factor": "wbc", "points": 0, "present": false } ], "wbc_per_ul": 8.0e3, "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "citation": { "authors": "Bone RC, Balk RA, Cerra FB, et al.", "doi": "10.1378/chest.101.6.1644", "id": "bone-1992", "source": "Chest. 1992;101(6):1644-1655", "title": "Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis" }, "formula": "sirs", "formula_expression": "SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4", "max_score": 4, "temperature_c": 37.0, "heart_rate_bpm": 80, "respiratory_rate": 16, "sirs_criteria_met": 0, "sirs_present": false } ``` ## Errors - HTTP 400 `invalid_temperature`: temperature_c must be a number from 30.0 to 45.0. Returned before settlement; you are not charged. - HTTP 400 `invalid_heart_rate`: heart_rate_bpm must be an integer from 30 to 220 Returned before settlement; you are not charged. - HTTP 400 `invalid_respiratory_rate`: respiratory_rate must be an integer from 4 to 80. Returned before settlement; you are not charged. - HTTP 400 `invalid_wbc`: wbc_k_ul (0.01-500) or wbc_ul (10-500000) is required Returned before settlement; you are not charged. - HTTP 400 `invalid_paco2`: paco2_mm_hg must be a number from 8 to 80. Returned before settlement; you are not charged. - HTTP 400 `invalid_band_percent`: band_percent must be a number from 0 to 100 Returned before settlement; you are not charged. - HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged. - HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged. - HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged. Shared HTTP 402 and 503: https://magentlab.com/docs/payments ## Related tools - [SOFA](https://magentlab.com/docs/sofa) — Compute the Vincent 1996 SOFA score from PaO2/FiO2, platelets, bilirubin, MAP and adrenergic agents, GCS, and creatinine or urine output. - [qSOFA](https://magentlab.com/docs/qsofa) — Compute the Sepsis-3 qSOFA score from respiratory rate, caller-assigned altered mentation, and systolic blood pressure. ## Payment Required query parameters must be present and valid. Invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. - GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall). - HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote. - Sign EIP-3009 (scheme exact, assetTransferMethod eip3009) with validBefore = now + accepts[0].maxTimeoutSeconds (600 seconds). That window starts when you sign and must cover wallet confirmation plus CDP verify and settle. Magent retries transient facilitator 429/5xx before answering. Do not send upto or batch-settlement payloads; magent does not offer those schemes. - Retry the same URL with PAYMENT-SIGNATURE (base64 JSON echoing accepted, payload, and extensions when present). - Success is HTTP 200 JSON plus PAYMENT-RESPONSE. Settlement happens before the tool runs. HTTP 503 settlement_uncertain or settle_failed: retry the same PAYMENT-SIGNATURE. Mint a new nonce only after a new HTTP 402. - offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront. - not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search. - not offered `batch-settlement`: Not offered. Payment-channel vouchers claimed later in batches. Not the same as POST {items} bulk (that is still exact). Same-path POST {items} is still scheme exact: one EIP-3009 authorization for n times the GET unit. That is not x402 batch-settlement (payment channels / vouchers). Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments Stdio MCP (one process per host): https://magentlab.com/docs/mcp ## Guarantees - Invalid query parameters return HTTP 400 before settlement. You are not charged. - Settlement finishes before the tool executes (paymentFlow upfront). Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE. - HTTP 402 is unpaid only. Do not sign a second authorization because of a 503. - Execution is timeout-bounded and concurrency-capped. - Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.