# SOFA organ failure score SOFA ## Also searched as - SOFA score - Sequential Organ Failure Assessment - Sepsis-related Organ Failure Assessment - Vincent SOFA - organ failure score Status: LIVE Price: $0.005 USDC `GET /api/calc/sofa` HTML: https://magentlab.com/docs/sofa Markdown: https://magentlab.com/docs/sofa.md Not a medical device. Not a diagnosis, dose, or listing recommendation. ## What it computes Compute the Vincent 1996 SOFA score from PaO2/FiO2, platelets, bilirubin, MAP and adrenergic agents, GCS, and creatinine or urine output. ## When to use When an agent needs the published six-organ SOFA total and must not invent points from a chart narrative or a later SOFA revision. ## When not to use - Not a Sepsis-3 diagnosis and not a treatment recommendation. - Respiration scores 3 and 4 require respiratory support (ventilated=true) as in Vincent 1996 Table 3. Unventilated PaO2/FiO2 <200 is capped at 2. - Adrenergic doses are scored without the paper's ≥1 h duration. Only dopamine, epinephrine, norepinephrine, and dobutamine from Vincent 1996 Table 3 are scored. - GCS is a caller-assigned integer 3-15. magent does not examine the patient. ## Formula ``` SOFA = respiration + coagulation + liver + cardiovascular + cns + renal; each 0-4; max 24 ``` ## Citation [The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure](https://doi.org/10.1007/BF01709751) Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG Intensive Care Med. 1996;22(7):707-710 DOI: [10.1007/BF01709751](https://doi.org/10.1007/BF01709751) ## Worked example ### All organs 0 Given: `bilirubin_mg_dl=0.8, creatinine_mg_dl=1.0, fio2=0.21, gcs=15, map_mm_hg=80, pao2_mm_hg=96, platelets_10e9_l=200, ventilated=false` 1. PaO2/FiO2 96/0.21 ≥400 → 0; platelets 200 → 0; bilirubin 0.8 → 0; MAP 80, no pressors → 0; GCS 15 → 0; creatinine 1.0 → 0 2. Score = 0 (max 24) ### Unventilated PaO2/FiO2 80 stays 2 Given: `bilirubin_mg_dl=0.8, creatinine_mg_dl=1.0, fio2=1.0, gcs=15, map_mm_hg=80, pao2_mm_hg=80, platelets_10e9_l=200, ventilated=false` 1. PaO2/FiO2 80 without ventilation cannot score 3 or 4 2. Respiration → 2; other organs 0; score = 2 ## Parameters - `pao2_mm_hg` (number, required): Arterial PaO2 in mm Hg (20-700). Respiration uses PaO2/FiO2: ≥400 scores 0; <400 scores 1; <300 scores 2; <200 with ventilation scores 3; <100 with ventilation scores 4. - `fio2` (number, required): Inspired oxygen as a fraction (0.21-1.0), not a percent. - `ventilated` (boolean, required): Respiratory support (Vincent 1996). true or false. Scores 3 and 4 require ventilation; unventilated PaO2/FiO2 <200 is capped at 2. - `platelets_10e9_l` (number, required): Platelets ×10^9/L, same as ×10^3/mm^3 (1-2000). ≥150 scores 0; <150 scores 1; <100 scores 2; <50 scores 3; <20 scores 4. - `bilirubin_mg_dl` (number, optional): Total bilirubin in mg/dL (0.1-40). Provide this or bilirubin_umol_l. <1.2 scores 0; 1.2-1.9 scores 1; 2.0-5.9 scores 2; 6.0-11.9 scores 3; >12.0 scores 4. - `bilirubin_umol_l` (number, optional): Total bilirubin in µmol/L. Converted as mg/dL = µmol/L / 17.1. - `map_mm_hg` (number, required): Mean arterial pressure in mm Hg (30-180). MAP <70 scores 1 unless a higher cardiovascular band applies. - `dopamine_ug_kg_min` (number, optional): Dopamine in µg/kg·min (0-50) when provided. Absent is 0. 0 < dose ≤5 scores 2; >5 scores 3; >15 scores 4. - `dobutamine` (boolean, optional): Any dobutamine. true or false when provided; absent is false. true scores cardiovascular 2 unless a higher band applies. - `epinephrine_ug_kg_min` (number, optional): Epinephrine in µg/kg·min (0-2) when provided. Absent is 0. 0 < dose ≤0.1 scores 3; >0.1 scores 4. - `norepinephrine_ug_kg_min` (number, optional): Norepinephrine in µg/kg·min (0-2) when provided. Absent is 0. 0 < dose ≤0.1 scores 3; >0.1 scores 4. - `gcs` (integer, required): Glasgow Coma Scale total as assigned by the caller (integer 3-15). 15 scores 0; 13-14 scores 1; 10-12 scores 2; 6-9 scores 3; <6 scores 4. - `creatinine_mg_dl` (number, optional): Creatinine in mg/dL (0.1-20). Provide this, creatinine_umol_l, or urine_output_ml_day. <1.2 scores 0; 1.2-1.9 scores 1; 2.0-3.4 scores 2; 3.5-4.9 scores 3; ≥5.0 scores 4. - `creatinine_umol_l` (number, optional): Creatinine in µmol/L. Converted as mg/dL = µmol/L / 88.42. - `urine_output_ml_day` (number, optional): Urine output in mL/day (0-20000) when provided. <200 scores 4; <500 scores 3; otherwise urine does not add 1-2. Renal is the max of creatinine and urine when both are given. ## Bulk (POST) POST the same path with a JSON items array. Price is n times the GET unit. Invalid items return HTTP 400 before settlement. Method: `POST /api/calc/sofa` Max items: 25 Price: unit_amount * n (unit 5000 atomic) Status: PREVIEW - 1 to 25 items. Each item uses the same keys as the GET query parameters. - The first invalid item fails the whole request (index in the 400 JSON). You are not charged. - HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row. - Catalog misses (empty matches, found=false) stay paid 200s inside that slot. - x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items. Example request: ```json { "items": [ { "bilirubin_mg_dl": "0.8", "creatinine_mg_dl": "1.0", "fio2": "0.21", "gcs": "15", "map_mm_hg": "80", "pao2_mm_hg": "96", "platelets_10e9_l": "200", "ventilated": "false" }, { "bilirubin_mg_dl": "0.8", "creatinine_mg_dl": "1.0", "fio2": "0.21", "gcs": "15", "map_mm_hg": "80", "pao2_mm_hg": "96", "platelets_10e9_l": "200", "ventilated": "false" } ] } ``` Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/sofa Example 200: ```json { "count": 2, "path": "/api/calc/sofa", "items": [ { "components": [ { "value": 457.14285714285717, "factor": "respiration", "points": 0, "present": false }, { "value": 200.0, "factor": "coagulation", "points": 0, "present": false }, { "value": 0.8, "factor": "liver", "points": 0, "present": false }, { "value": 80.0, "factor": "cardiovascular", "points": 0, "present": false }, { "value": 15, "factor": "cns", "points": 0, "present": false }, { "value": 1.0, "factor": "renal", "points": 0, "present": false } ], "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "citation": { "authors": "Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG", "doi": "10.1007/BF01709751", "id": "vincent-1996", "source": "Intensive Care Med. 1996;22(7):707-710", "title": "The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure" }, "formula": "sofa", "formula_expression": "SOFA = respiration + coagulation + liver + cardiovascular + cns + renal; each 0-4; max 24", "max_score": 24, "score": 0 }, { "components": [ { "value": 457.14285714285717, "factor": "respiration", "points": 0, "present": false }, { "value": 200.0, "factor": "coagulation", "points": 0, "present": false }, { "value": 0.8, "factor": "liver", "points": 0, "present": false }, { "value": 80.0, "factor": "cardiovascular", "points": 0, "present": false }, { "value": 15, "factor": "cns", "points": 0, "present": false }, { "value": 1.0, "factor": "renal", "points": 0, "present": false } ], "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "citation": { "authors": "Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG", "doi": "10.1007/BF01709751", "id": "vincent-1996", "source": "Intensive Care Med. 1996;22(7):707-710", "title": "The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure" }, "formula": "sofa", "formula_expression": "SOFA = respiration + coagulation + liver + cardiovascular + cns + renal; each 0-4; max 24", "max_score": 24, "score": 0 } ] } ``` ## Response fields - `formula` (string): sofa - `formula_expression` (string): Exact expression used - `score` (integer): Total points 0-24 - `max_score` (integer): Always 24 - `components` (array): Per-organ 0-4 points - `citation` (object): Vincent 1996 citation - `disclaimer` (string): Not-a-device notice ## Example JSON Frozen fixture. Not a live lookup. ```json { "components": [ { "value": 457.14285714285717, "factor": "respiration", "points": 0, "present": false }, { "value": 200.0, "factor": "coagulation", "points": 0, "present": false }, { "value": 0.8, "factor": "liver", "points": 0, "present": false }, { "value": 80.0, "factor": "cardiovascular", "points": 0, "present": false }, { "value": 15, "factor": "cns", "points": 0, "present": false }, { "value": 1.0, "factor": "renal", "points": 0, "present": false } ], "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "citation": { "authors": "Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG", "doi": "10.1007/BF01709751", "id": "vincent-1996", "source": "Intensive Care Med. 1996;22(7):707-710", "title": "The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure" }, "formula": "sofa", "formula_expression": "SOFA = respiration + coagulation + liver + cardiovascular + cns + renal; each 0-4; max 24", "max_score": 24, "score": 0 } ``` ## Errors - HTTP 400 `invalid_pao2`: pao2_mm_hg must be a number from 20 to 700. Returned before settlement; you are not charged. - HTTP 400 `invalid_fio2`: fio2 must be a fraction from 0.21 to 1.0. Returned before settlement; you are not charged. - HTTP 400 `invalid_flag`: boolean clinical flags must be true or false Returned before settlement; you are not charged. - HTTP 400 `invalid_platelets`: platelets_10e9_l must be a number from 1 to 2000 Returned before settlement; you are not charged. - HTTP 400 `invalid_bilirubin`: bilirubin_mg_dl (0.1-40) or bilirubin_umol_l (2-684) is required Returned before settlement; you are not charged. - HTTP 400 `invalid_map_mm_hg`: map_mm_hg must be a number from 30 to 180. Returned before settlement; you are not charged. - HTTP 400 `invalid_dopamine`: dopamine_ug_kg_min must be a number from 0 to 50 when provided. Returned before settlement; you are not charged. - HTTP 400 `invalid_epinephrine`: epinephrine_ug_kg_min must be a number from 0 to 2 when provided. Returned before settlement; you are not charged. - HTTP 400 `invalid_norepinephrine`: norepinephrine_ug_kg_min must be a number from 0 to 2 when provided. Returned before settlement; you are not charged. - HTTP 400 `invalid_sofa_gcs`: gcs must be an integer from 3 to 15. Returned before settlement; you are not charged. - HTTP 400 `invalid_creatinine`: creatinine_mg_dl (0.1-20) or creatinine_umol_l (9-1768) is required Returned before settlement; you are not charged. - HTTP 400 `invalid_urine_output`: urine_output_ml_day must be a number from 0 to 20000 when provided. Returned before settlement; you are not charged. - HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged. - HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged. - HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged. Shared HTTP 402 and 503: https://magentlab.com/docs/payments ## Related tools - [qSOFA](https://magentlab.com/docs/qsofa) — Compute the Sepsis-3 qSOFA score from respiratory rate, caller-assigned altered mentation, and systolic blood pressure. ## Payment Required query parameters must be present and valid. Invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. - GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall). - HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote. - Sign EIP-3009 (scheme exact, assetTransferMethod eip3009) with validBefore = now + accepts[0].maxTimeoutSeconds (600 seconds). That window starts when you sign and must cover wallet confirmation plus CDP verify and settle. Magent retries transient facilitator 429/5xx before answering. Do not send upto or batch-settlement payloads; magent does not offer those schemes. - Retry the same URL with PAYMENT-SIGNATURE (base64 JSON echoing accepted, payload, and extensions when present). - Success is HTTP 200 JSON plus PAYMENT-RESPONSE. Settlement happens before the tool runs. HTTP 503 settlement_uncertain or settle_failed: retry the same PAYMENT-SIGNATURE. Mint a new nonce only after a new HTTP 402. - offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront. - not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search. - not offered `batch-settlement`: Not offered. Payment-channel vouchers claimed later in batches. Not the same as POST {items} bulk (that is still exact). Same-path POST {items} is still scheme exact: one EIP-3009 authorization for n times the GET unit. That is not x402 batch-settlement (payment channels / vouchers). Shared HTTP 402 and 503 table: https://magentlab.com/docs/payments Stdio MCP (one process per host): https://magentlab.com/docs/mcp ## Guarantees - Invalid query parameters return HTTP 400 before settlement. You are not charged. - Settlement finishes before the tool executes (paymentFlow upfront). Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE. - HTTP 402 is unpaid only. Do not sign a second authorization because of a 503. - Execution is timeout-bounded and concurrency-capped. - Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.