# TIMI risk score for STEMI

Status: LIVE
Price: $0.005 USDC
`GET /api/calc/timi_stemi`
HTML: https://magentlab.com/docs/timi-stemi
Markdown: https://magentlab.com/docs/timi-stemi.md

Not a medical device. Not a diagnosis, dose, or listing recommendation.

## What it computes

Compute the TIMI risk score for ST-elevation myocardial infarction from published bedside factors at presentation.

## When to use

When an agent needs the Morrow 2000 TIMI STEMI arithmetic and must not invent points from a chart narrative.

## When not to use

- Not a reperfusion or fibrinolytic protocol. The response is the integer score and components, not a mortality percent or treatment recommendation.
- Age 65–74 and age ≥75 are mutually exclusive. Killip class, anterior ST elevation or LBBB, and time to treatment are caller-assigned; magent does not read an ECG or compute timestamps.
- Diabetes, hypertension, or angina history contribute one point if any is true (not additive).

## Formula

```
TIMI STEMI = age 65-74 (2) or age >=75 (3) + diabetes/hypertension/angina (1) + SBP<100 (3) + HR>100 (2) + Killip II-IV (2) + weight<67 kg (1) + anterior STE or LBBB (1) + time to treatment >4 h (1); max 14
```

## Citation

TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation
Morrow DA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, Giugliano RP, McCabe CH, Braunwald E
Circulation. 2000;102(17):2031-2037
DOI: [10.1161/01.CIR.102.17.2031](https://doi.org/10.1161/01.CIR.102.17.2031)

## Worked example

### All-negative adult

Given: `age=50, angina=false, anterior_ste_or_lbbb=false, diabetes=false, heart_rate_bpm=70, hypertension=false, killip_class=1, systolic_mm_hg=120, time_to_treatment_gt_4h=false, weight_kg=80`

1. Age 50 (<65) → 0; no diabetes/hypertension/angina; SBP 120 (≥100); HR 70 (≤100); Killip I; weight 80 kg (≥67); no anterior STE/LBBB; time to treatment not >4 h
2. Score = 0


## Parameters

- `age` (integer, required): Age in years (18-120). 65-74 scores 2; ≥75 scores 3. Bands are exclusive.
- `diabetes` (boolean, required): Diabetes mellitus. true or false. Diabetes, hypertension, or angina scores 1 if any is true.
- `hypertension` (boolean, required): Hypertension history. true or false.
- `angina` (boolean, required): Angina history. true or false.
- `systolic_mm_hg` (number, required): Systolic BP in mm Hg (50-250). Scores 3 when <100; 100 is negative.
- `heart_rate_bpm` (integer, required): Heart rate in beats per minute (integer 30-220). Scores 2 when >100; 100 is negative.
- `killip_class` (integer, required): Killip class 1-4. Classes II-IV score 2; class I scores 0. Caller-assigned.
- `weight_kg` (number, optional): Weight in kilograms. Provide weight_kg or weight_lb. Scores 1 when <67 kg; 67 is negative.
- `weight_lb` (number, optional): Weight in pounds. Converted to kg; the <67 kg cutoff is applied in kg.
- `anterior_ste_or_lbbb` (boolean, required): Anterior ST elevation or LBBB. true or false. Caller-assigned; magent does not read tracings.
- `time_to_treatment_gt_4h` (boolean, required): Time to treatment >4 hours. true or false. Caller-assigned; magent does not parse timestamps.

## Bulk (POST)

POST the same path with a JSON items array. Price is n times the GET unit. Invalid items return HTTP 400 before settlement.

Method: `POST /api/calc/timi_stemi`
Max items: 25
Price: unit_amount * n (unit 5000 atomic)
Status: PREVIEW

- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request:

```json
{
  "items": [
    {
      "age": "50",
      "angina": "false",
      "anterior_ste_or_lbbb": "false",
      "diabetes": "false",
      "heart_rate_bpm": "70",
      "hypertension": "false",
      "killip_class": "1",
      "systolic_mm_hg": "120",
      "time_to_treatment_gt_4h": "false",
      "weight_kg": "80"
    },
    {
      "age": "50",
      "angina": "false",
      "anterior_ste_or_lbbb": "false",
      "diabetes": "false",
      "heart_rate_bpm": "70",
      "hypertension": "false",
      "killip_class": "1",
      "systolic_mm_hg": "120",
      "time_to_treatment_gt_4h": "false",
      "weight_kg": "80"
    }
  ]
}
```

Human paywall (two-item fixture): https://api.magentlab.com/paywall/bulk/timi-stemi

Example 200:

```json
{
  "count": 2,
  "path": "/api/calc/timi_stemi",
  "items": [
    {
      "components": [
        {
          "value": 50,
          "factor": "age_65_74",
          "points": 0,
          "present": false
        },
        {
          "value": 50,
          "factor": "age_ge_75",
          "points": 0,
          "present": false
        },
        {
          "factor": "history_cad_risk",
          "points": 0,
          "present": false
        },
        {
          "value": 120.0,
          "factor": "systolic_bp_lt_100",
          "points": 0,
          "present": false
        },
        {
          "value": 70,
          "factor": "heart_rate_gt_100",
          "points": 0,
          "present": false
        },
        {
          "value": 1,
          "factor": "killip_ii_iv",
          "points": 0,
          "present": false
        },
        {
          "value": 80.0,
          "factor": "weight_lt_67",
          "points": 0,
          "present": false
        },
        {
          "factor": "anterior_ste_or_lbbb",
          "points": 0,
          "present": false
        },
        {
          "factor": "time_to_treatment_gt_4h",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Morrow DA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, Giugliano RP, McCabe CH, Braunwald E",
        "doi": "10.1161/01.CIR.102.17.2031",
        "id": "morrow-2000",
        "source": "Circulation. 2000;102(17):2031-2037",
        "title": "TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation"
      },
      "formula": "timi_stemi",
      "formula_expression": "TIMI STEMI = age 65-74 (2) or age >=75 (3) + diabetes/hypertension/angina (1) + SBP<100 (3) + HR>100 (2) + Killip II-IV (2) + weight<67 kg (1) + anterior STE or LBBB (1) + time to treatment >4 h (1); max 14",
      "weight_kg": 80.0,
      "age_years": 50,
      "max_score": 14,
      "score": 0,
      "systolic_mm_hg": 120.0,
      "heart_rate_bpm": 70,
      "angina": false,
      "anterior_ste_or_lbbb": false,
      "diabetes": false,
      "history_cad_risk": false,
      "hypertension": false,
      "killip_class": 1,
      "time_to_treatment_gt_4h": false
    },
    {
      "components": [
        {
          "value": 50,
          "factor": "age_65_74",
          "points": 0,
          "present": false
        },
        {
          "value": 50,
          "factor": "age_ge_75",
          "points": 0,
          "present": false
        },
        {
          "factor": "history_cad_risk",
          "points": 0,
          "present": false
        },
        {
          "value": 120.0,
          "factor": "systolic_bp_lt_100",
          "points": 0,
          "present": false
        },
        {
          "value": 70,
          "factor": "heart_rate_gt_100",
          "points": 0,
          "present": false
        },
        {
          "value": 1,
          "factor": "killip_ii_iv",
          "points": 0,
          "present": false
        },
        {
          "value": 80.0,
          "factor": "weight_lt_67",
          "points": 0,
          "present": false
        },
        {
          "factor": "anterior_ste_or_lbbb",
          "points": 0,
          "present": false
        },
        {
          "factor": "time_to_treatment_gt_4h",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Morrow DA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, Giugliano RP, McCabe CH, Braunwald E",
        "doi": "10.1161/01.CIR.102.17.2031",
        "id": "morrow-2000",
        "source": "Circulation. 2000;102(17):2031-2037",
        "title": "TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation"
      },
      "formula": "timi_stemi",
      "formula_expression": "TIMI STEMI = age 65-74 (2) or age >=75 (3) + diabetes/hypertension/angina (1) + SBP<100 (3) + HR>100 (2) + Killip II-IV (2) + weight<67 kg (1) + anterior STE or LBBB (1) + time to treatment >4 h (1); max 14",
      "weight_kg": 80.0,
      "age_years": 50,
      "max_score": 14,
      "score": 0,
      "systolic_mm_hg": 120.0,
      "heart_rate_bpm": 70,
      "angina": false,
      "anterior_ste_or_lbbb": false,
      "diabetes": false,
      "history_cad_risk": false,
      "hypertension": false,
      "killip_class": 1,
      "time_to_treatment_gt_4h": false
    }
  ]
}
```

## Response fields

- `formula` (string): timi_stemi
- `formula_expression` (string): Exact expression used
- `score` (integer): Total points 0-14
- `max_score` (integer): Always 14
- `age_years` (integer): Age used for the 65-74 and ≥75 bands
- `diabetes` (boolean): Diabetes flag used
- `hypertension` (boolean): Hypertension flag used
- `angina` (boolean): Angina flag used
- `history_cad_risk` (boolean): true when diabetes, hypertension, or angina is true
- `systolic_mm_hg` (number): Systolic BP used for the <100 cutoff
- `heart_rate_bpm` (integer): Heart rate used for the >100 cutoff
- `killip_class` (integer): Killip class 1-4 used
- `weight_kg` (number): Normalized weight in kg
- `anterior_ste_or_lbbb` (boolean): Anterior STE or LBBB flag used
- `time_to_treatment_gt_4h` (boolean): Time to treatment >4 hours flag used
- `components` (array): Per-factor points
- `citation` (object): Circulation 2000 citation
- `disclaimer` (string): Not-a-device notice

## Example JSON

Frozen fixture. Not a live lookup.

```json
{
  "components": [
    {
      "value": 50,
      "factor": "age_65_74",
      "points": 0,
      "present": false
    },
    {
      "value": 50,
      "factor": "age_ge_75",
      "points": 0,
      "present": false
    },
    {
      "factor": "history_cad_risk",
      "points": 0,
      "present": false
    },
    {
      "value": 120.0,
      "factor": "systolic_bp_lt_100",
      "points": 0,
      "present": false
    },
    {
      "value": 70,
      "factor": "heart_rate_gt_100",
      "points": 0,
      "present": false
    },
    {
      "value": 1,
      "factor": "killip_ii_iv",
      "points": 0,
      "present": false
    },
    {
      "value": 80.0,
      "factor": "weight_lt_67",
      "points": 0,
      "present": false
    },
    {
      "factor": "anterior_ste_or_lbbb",
      "points": 0,
      "present": false
    },
    {
      "factor": "time_to_treatment_gt_4h",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Morrow DA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, Giugliano RP, McCabe CH, Braunwald E",
    "doi": "10.1161/01.CIR.102.17.2031",
    "id": "morrow-2000",
    "source": "Circulation. 2000;102(17):2031-2037",
    "title": "TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation"
  },
  "formula": "timi_stemi",
  "formula_expression": "TIMI STEMI = age 65-74 (2) or age >=75 (3) + diabetes/hypertension/angina (1) + SBP<100 (3) + HR>100 (2) + Killip II-IV (2) + weight<67 kg (1) + anterior STE or LBBB (1) + time to treatment >4 h (1); max 14",
  "weight_kg": 80.0,
  "age_years": 50,
  "max_score": 14,
  "score": 0,
  "systolic_mm_hg": 120.0,
  "heart_rate_bpm": 70,
  "angina": false,
  "anterior_ste_or_lbbb": false,
  "diabetes": false,
  "history_cad_risk": false,
  "hypertension": false,
  "killip_class": 1,
  "time_to_treatment_gt_4h": false
}
```

## Errors

- HTTP 400 `invalid_age`: age must be an integer from 18 to 120 Returned before settlement; you are not charged.
- HTTP 400 `invalid_flag`: boolean clinical flags must be true or false Returned before settlement; you are not charged.
- HTTP 400 `invalid_systolic_bp`: systolic_mm_hg or systolic_bp_mm_hg must be a number from 50 to 250. Returned before settlement; you are not charged.
- HTTP 400 `invalid_heart_rate`: heart_rate_bpm must be an integer from 30 to 220 Returned before settlement; you are not charged.
- HTTP 400 `invalid_killip_class`: killip_class must be 1, 2, 3, or 4. Returned before settlement; you are not charged.
- HTTP 400 `invalid_weight`: weight_kg (1-500) or weight_lb (2-1100) is required Returned before settlement; you are not charged.
- HTTP 400 `invalid_items`: POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
- HTTP 400 `invalid_item_count`: items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
- HTTP 400 `invalid_item`: each items entry must be a JSON object Returned before settlement; you are not charged.
- HTTP 402 `payment_required`: Missing or invalid PAYMENT-SIGNATURE; decode the PAYMENT-REQUIRED header
- HTTP 409 `payment_in_progress`: The same authorization nonce is already being settled; retry shortly
- HTTP 429 `rate_limited`: Too many requests from this client
- HTTP 503 `settlement_uncertain`: Settlement is unconfirmed; retry with the same PAYMENT-SIGNATURE
- HTTP 503 `settle_failed`: Settlement failed; retry with the same PAYMENT-SIGNATURE shortly
- HTTP 503 `facilitator_unavailable`: Payment facilitator unavailable
- HTTP 503 `facilitator_misconfigured`: Payment facilitator is not configured
- HTTP 503 `facilitator_unauthorized`: Payment facilitator rejected credentials
- HTTP 503 `ledger_unavailable`: Payment ledger unavailable
- HTTP 503 `payment_unavailable`: Payment processing unavailable

## Related tools

- [TIMI UA/NSTEMI](https://magentlab.com/docs/timi-ua-nstemi) — Compute the TIMI risk score for unstable angina / NSTEMI from age and six caller-assigned flags.

## Also searched as

- TIMI STEMI
- TIMI risk score STEMI
- Morrow TIMI STEMI
- TIMI ST-elevation MI
- STEMI TIMI score

## Payment

Required query parameters must be present and valid. Invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s.

- GET the tool with Accept: application/json (do not send Accept: text/html unless you want the human paywall).
- HTTP 402 means you have not paid. Decode the base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote.
- Sign EIP-3009 (scheme exact, assetTransferMethod eip3009) with validBefore = now + accepts[0].maxTimeoutSeconds (600 seconds). That window starts when you sign and must cover wallet confirmation plus CDP verify and settle. Magent retries transient facilitator 429/5xx before answering. Do not send upto or batch-settlement payloads; magent does not offer those schemes.
- Retry the same URL with PAYMENT-SIGNATURE (base64 JSON echoing accepted, payload, and extensions when present).
- Success is HTTP 200 JSON plus PAYMENT-RESPONSE. Settlement happens before the tool runs. HTTP 503 settlement_uncertain or settle_failed: retry the same PAYMENT-SIGNATURE. Mint a new nonce only after a new HTTP 402.

- offered `exact` on eip155:8453: Fixed-price USDC on Base. The buyer authorizes the advertised amount (EIP-3009). magent settles before the tool runs (paymentFlow upfront). extra.assetTransferMethod=eip3009 extra.paymentFlow=upfront.

- not offered `upto`: Not offered. Usage-based: buyer authorizes a ceiling, seller settles the actual amount after work. Reserved for a future metered tool. Not for current calculators or code search.
- not offered `batch-settlement`: Not offered. Payment-channel vouchers claimed later in batches. Not the same as POST {items} bulk (that is still exact).

Same-path POST {items} is still scheme exact: one EIP-3009 authorization for n times the GET unit. That is not x402 batch-settlement (payment channels / vouchers).

## Guarantees

- Invalid query parameters return HTTP 400 before settlement. You are not charged.
- Settlement finishes before the tool executes (paymentFlow upfront). Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.
