ATLAS C. difficile infection score

ATLAS

Sum the Miller 2013 five-component ATLAS bedside score (age, systemic antibiotics during CDI therapy, leukocyte count, albumin, serum creatinine) and return the published predicted-cure percent.

LIVE $0.005 USDC GET /api/calc/atlas

Markdown: /docs/atlas.md · Canonical: https://magentlab.com/docs/atlas

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Sum the Miller 2013 five-component ATLAS bedside score (age, systemic antibiotics during CDI therapy, leukocyte count, albumin, serum creatinine) and return the published predicted-cure percent.

When to use

When an agent has age, concurrent systemic antibiotics, WBC, albumin, and creatinine and needs the published Miller 2013 ATLAS total and predicted-cure percent, not a Clostridioides difficile diagnosis and not a metronidazole, vancomycin, or fidaxomicin order.

When not to use

Not a medical device. Not a Clostridioides difficile (C. difficile) diagnosis and not a metronidazole, vancomycin, or fidaxomicin order. magent does not culture stool.
Miller 2013 five-component ATLAS only (Age, Treatment with systemic antibiotics, Leukocyte count, Albumin, Serum creatinine). Temperature was a Table 1 candidate and is not scored; the final ATLAS dropped it. magent does not assay labs.
Predicted cure percent is 100 − 5.08 × score from the paper regression, rounded to one decimal (score 0 is 100.0). The paper reports eleven score categories 0–10; this tool does not invent mild/moderate/severe bands.

Formula

ATLAS = age (<60 0, 60–79 1, ≥80 2) + systemic_antibiotics (false 0, true 2) + leukocyte (<16 ×10^9/L 0, 16–25 1, >25 2) + albumin (>35 g/L 0, 26–35 1, ≤25 2) + creatinine (≤120 µmol/L 0, 121–179 1, ≥180 2); Miller 2013 Table 1 five-component ATLAS; max 10; predicted_cure_percent = 100 − 5.08 × score (1 decimal)

Citation

Title: Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy
Authors: Miller MA, Louie T, Mullane K, Weiss K, Lentnek A, Golan Y, Kean Y, Sears P
Source: BMC Infect Dis. 2013;13:148
DOI: 10.1186/1471-2334-13-148

Worked example

All components 0

Given: age=40albumin_g_l=40creatinine_umol_l=80systemic_antibiotics=falsewbc_k_ul=8

Age 40 <60 → 0; no systemic antibiotics → 0; WBC 8 ×10^9/L <16 → 0; albumin 40 g/L >35 → 0; creatinine 80 µmol/L ≤120 → 0
Score = 0 (max 10); predicted_cure_percent = 100.0

Systemic antibiotics during CDI therapy

Given: age=40albumin_g_l=40creatinine_umol_l=80systemic_antibiotics=truewbc_k_ul=8

Systemic antibiotics true → 2; remaining components 0
Score = 2; predicted_cure_percent = 100 − 5.08 × 2 = 89.8

Also searched as

atlas c diff
cdi atlas
clostridioides difficile
ATLAS score
C. difficile ATLAS
Clostridium difficile ATLAS
Miller ATLAS
CDI bedside score

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/atlas?age=40&systemic_antibiotics=false&wbc_k_ul=8&albumin_g_l=40&creatinine_umol_l=80

Full URL: https://api.magentlab.com/api/calc/atlas?age=40&systemic_antibiotics=false&wbc_k_ul=8&albumin_g_l=40&creatinine_umol_l=80

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/atlas?age=40&systemic_antibiotics=false&wbc_k_ul=8&albumin_g_l=40&creatinine_umol_l=80"

Parameters

Name	Type	Required	Description
`age`	integer	required	Age in years (18-120). Miller 2013 Table 1: <60 scores 0; 60–79 inclusive scores 1; ≥80 scores 2.
`systemic_antibiotics`	boolean	required	Systemic antibiotics on one or more days of CDI therapy (Miller 2013). true scores 2; false scores 0. There is no 1-point cell. magent does not review the medication list.
`wbc_k_ul`	number	optional	Total leukocyte count in 10^3/µL (same as ×10^9/L). Provide wbc_k_ul or wbc_ul, not both. Range 0.01-500. Miller 2013: <16 scores 0; 16–25 inclusive scores 1; >25 scores 2.
`wbc_ul`	number	optional	Total leukocyte count in cells/µL. Provide wbc_k_ul or wbc_ul, not both. Range 10-500000. Miller 2013: <16000 scores 0; 16000–25000 inclusive scores 1; >25000 scores 2.
`albumin_g_l`	number	optional	Serum albumin in g/L (10-60). Provide this or albumin_g_dl, not both. Miller 2013: >35 scores 0; 26–35 inclusive scores 1; ≤25 scores 2. magent does not assay albumin.
`albumin_g_dl`	number	optional	Serum albumin in g/dL (1-6). Converted as g/L = g/dL × 10. Provide this or albumin_g_l, not both.
`creatinine_umol_l`	number	optional	Serum creatinine in µmol/L (9-1768). Provide this or creatinine_mg_dl, not both. Miller 2013: ≤120 scores 0; 121–179 inclusive scores 1; ≥180 scores 2. magent does not assay creatinine.
`creatinine_mg_dl`	number	optional	Serum creatinine in mg/dL (0.1-20). Converted as µmol/L = mg/dL × 88.42. Provide this or creatinine_umol_l, not both.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/atlas Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "40",
      "albumin_g_l": "40",
      "creatinine_umol_l": "80",
      "systemic_antibiotics": "false",
      "wbc_k_ul": "8"
    },
    {
      "age": "40",
      "albumin_g_l": "40",
      "creatinine_umol_l": "80",
      "systemic_antibiotics": "false",
      "wbc_k_ul": "8"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/atlas",
  "items": [
    {
      "components": [
        {
          "value": 40,
          "factor": "age",
          "points": 0,
          "present": false
        },
        {
          "factor": "systemic_antibiotics",
          "points": 0,
          "present": false
        },
        {
          "value": 8.0e3,
          "factor": "leukocyte",
          "points": 0,
          "present": false
        },
        {
          "value": 40.0,
          "factor": "albumin",
          "points": 0,
          "present": false
        },
        {
          "value": 80.0,
          "factor": "creatinine",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Miller MA, Louie T, Mullane K, Weiss K, Lentnek A, Golan Y, Kean Y, Sears P",
        "doi": "10.1186/1471-2334-13-148",
        "id": "miller-2013",
        "pmid": "23530807",
        "source": "BMC Infect Dis. 2013;13:148",
        "title": "Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy"
      },
      "formula": "atlas",
      "formula_expression": "ATLAS = age (<60 0, 60–79 1, ≥80 2) + systemic_antibiotics (false 0, true 2) + leukocyte (<16 ×10^9/L 0, 16–25 1, >25 2) + albumin (>35 g/L 0, 26–35 1, ≤25 2) + creatinine (≤120 µmol/L 0, 121–179 1, ≥180 2); Miller 2013 Table 1 five-component ATLAS; max 10; predicted_cure_percent = 100 − 5.08 × score (1 decimal)",
      "max_score": 10,
      "score": 0,
      "age_years": 40,
      "wbc_per_ul": 8.0e3,
      "albumin_g_l": 40.0,
      "atlas_score": 0,
      "creatinine_umol_l": 80.0,
      "predicted_cure_percent": 100.0,
      "systemic_antibiotics": false
    },
    {
      "components": [
        {
          "value": 40,
          "factor": "age",
          "points": 0,
          "present": false
        },
        {
          "factor": "systemic_antibiotics",
          "points": 0,
          "present": false
        },
        {
          "value": 8.0e3,
          "factor": "leukocyte",
          "points": 0,
          "present": false
        },
        {
          "value": 40.0,
          "factor": "albumin",
          "points": 0,
          "present": false
        },
        {
          "value": 80.0,
          "factor": "creatinine",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Miller MA, Louie T, Mullane K, Weiss K, Lentnek A, Golan Y, Kean Y, Sears P",
        "doi": "10.1186/1471-2334-13-148",
        "id": "miller-2013",
        "pmid": "23530807",
        "source": "BMC Infect Dis. 2013;13:148",
        "title": "Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy"
      },
      "formula": "atlas",
      "formula_expression": "ATLAS = age (<60 0, 60–79 1, ≥80 2) + systemic_antibiotics (false 0, true 2) + leukocyte (<16 ×10^9/L 0, 16–25 1, >25 2) + albumin (>35 g/L 0, 26–35 1, ≤25 2) + creatinine (≤120 µmol/L 0, 121–179 1, ≥180 2); Miller 2013 Table 1 five-component ATLAS; max 10; predicted_cure_percent = 100 − 5.08 × score (1 decimal)",
      "max_score": 10,
      "score": 0,
      "age_years": 40,
      "wbc_per_ul": 8.0e3,
      "albumin_g_l": 40.0,
      "atlas_score": 0,
      "creatinine_umol_l": 80.0,
      "predicted_cure_percent": 100.0,
      "systemic_antibiotics": false
    }
  ]
}

Response

Field	Type	Description
`formula`	string	atlas
`formula_expression`	string	Exact expression used
`score`	integer	ATLAS points 0-10
`atlas_score`	integer	Same integer as score
`max_score`	integer	10
`predicted_cure_percent`	number	Miller 2013 regression 100 − 5.08 × score, rounded to 1 decimal. Score 0 is 100.0. Not a named severity band.
`age_years`	integer	Age in years used
`systemic_antibiotics`	boolean	Systemic-antibiotics-during-CDI-therapy flag used
`wbc_per_ul`	number	Leukocyte count in cells/µL used
`albumin_g_l`	number	Serum albumin used in g/L (after g/dL conversion when supplied)
`creatinine_umol_l`	number	Serum creatinine used in µmol/L (after mg/dL conversion when supplied)
`components`	array	Per-factor Miller 2013 points
`citation`	object	Miller et al. BMC Infect Dis 2013 citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "components": [
    {
      "value": 40,
      "factor": "age",
      "points": 0,
      "present": false
    },
    {
      "factor": "systemic_antibiotics",
      "points": 0,
      "present": false
    },
    {
      "value": 8.0e3,
      "factor": "leukocyte",
      "points": 0,
      "present": false
    },
    {
      "value": 40.0,
      "factor": "albumin",
      "points": 0,
      "present": false
    },
    {
      "value": 80.0,
      "factor": "creatinine",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Miller MA, Louie T, Mullane K, Weiss K, Lentnek A, Golan Y, Kean Y, Sears P",
    "doi": "10.1186/1471-2334-13-148",
    "id": "miller-2013",
    "pmid": "23530807",
    "source": "BMC Infect Dis. 2013;13:148",
    "title": "Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy"
  },
  "formula": "atlas",
  "formula_expression": "ATLAS = age (<60 0, 60–79 1, ≥80 2) + systemic_antibiotics (false 0, true 2) + leukocyte (<16 ×10^9/L 0, 16–25 1, >25 2) + albumin (>35 g/L 0, 26–35 1, ≤25 2) + creatinine (≤120 µmol/L 0, 121–179 1, ≥180 2); Miller 2013 Table 1 five-component ATLAS; max 10; predicted_cure_percent = 100 − 5.08 × score (1 decimal)",
  "max_score": 10,
  "score": 0,
  "age_years": 40,
  "wbc_per_ul": 8.0e3,
  "albumin_g_l": 40.0,
  "atlas_score": 0,
  "creatinine_umol_l": 80.0,
  "predicted_cure_percent": 100.0,
  "systemic_antibiotics": false
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_age`	age must be an integer from 18 to 120 Returned before settlement; you are not charged.
400	`invalid_flag`	boolean clinical flags must be true or false Returned before settlement; you are not charged.
400	`invalid_wbc`	wbc_k_ul (0.01-500) or wbc_ul (10-500000) is required Returned before settlement; you are not charged.
400	`invalid_albumin`	albumin_g_dl (1-6) or albumin_g_l (10-60) is required Returned before settlement; you are not charged.
400	`invalid_creatinine`	creatinine_mg_dl (0.1-20) or creatinine_umol_l (9-1768) is required Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

None.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.