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CRUSADE bleeding score

Compute the CRUSADE in-hospital major bleeding score from hematocrit, caller-assigned Cockcroft–Gault creatinine clearance, heart rate, sex, signs of CHF, prior vascular disease, diabetes, and systolic BP (Subherwal 2009 Table 4).

LIVE $0.005 USDC GET /api/calc/crusade

Markdown: /docs/crusade.md · Canonical: https://magentlab.com/docs/crusade

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the CRUSADE in-hospital major bleeding score from hematocrit, caller-assigned Cockcroft–Gault creatinine clearance, heart rate, sex, signs of CHF, prior vascular disease, diabetes, and systolic BP (Subherwal 2009 Table 4).

When to use

When an agent needs the published Subherwal 2009 CRUSADE Table 4 total and in-hospital major-bleeding quintile for NSTE-ACS / NSTEMI and must not invent bands or compute Cockcroft–Gault.

When not to use

  • Not a medical device and not a treatment, transfusion, or anticoagulation recommendation.
  • Creatinine clearance is Cockcroft–Gault mL/min as assigned by the caller. magent does not compute Cockcroft–Gault.
  • Signs of CHF at presentation, prior vascular disease (PAD or prior stroke), and diabetes mellitus are caller-assigned. magent does not examine the patient.
  • This is the CRUSADE bleeding score for NSTE-ACS / NSTEMI (Subherwal 2009 Table 4). It is not a STEMI score and not TIMI.
  • Quintile percents are the published in-hospital major bleeding rates. max_score is the Table 4 sum of maxima (96). magent does not invent a 100 cap.

Formula

CRUSADE = hematocrit(<31:9, 31-<34:7, 34-<37:3, 37-<40:2, >=40:0) + crcl_ml_min(<=15:39, >15-30:35, >30-60:28, >60-90:17, >90-120:7, >120:0) + heart_rate(<=70:0, 71-80:1, 81-90:3, 91-100:6, 101-110:8, 111-120:10, >=121:11) + female(8) + signs_of_chf(7) + prior_vascular_disease(6) + diabetes(6) + systolic(<=90:10, 91-100:8, 101-120:5, 121-180:1, 181-200:3, >=201:5); Subherwal 2009 Table 4; quintiles <=20 3.1%, 21-30 5.5%, 31-40 8.6%, 41-50 11.9%, >50 19.5%; max 96

Citation

Title
Baseline risk of major bleeding in non–ST-segment-elevation myocardial infarction: the CRUSADE Bleeding Score
Authors
Subherwal S, Bach RG, Chen AY, et al.
Source
Circulation. 2009;119(14):1873-1882
DOI
10.1161/CIRCULATIONAHA.108.828541

Worked example

Low-risk NSTEMI baseline (score 1, very_low)

Given: crcl_ml_min=130diabetes=falseheart_rate_bpm=65hematocrit_percent=42prior_vascular_disease=falsesex=malesigns_of_chf=falsesystolic_mm_hg=140

  1. Hematocrit 42% ≥40 → 0; CrCl 130 mL/min >120 → 0; heart rate 65 ≤70 → 0
  2. Male → 0; no CHF → 0; no prior vascular disease → 0; no diabetes → 0; SBP 140 (121–180) → 1
  3. Score = 1 (max 96); crusade_band very_low; in-hospital major bleeding 3.1%

Also searched as

  • CRUSADE bleeding score
  • CRUSADE score
  • Subherwal bleeding score
  • NSTEMI bleeding risk
  • CRUSADE NSTE-ACS
  • in-hospital major bleeding CRUSADE

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/crusade?hematocrit_percent=42&crcl_ml_min=130&heart_rate_bpm=65&sex=male&signs_of_chf=false&prior_vascular_disease=false&diabetes=false&systolic_mm_hg=140

Full URL: https://api.magentlab.com/api/calc/crusade?hematocrit_percent=42&crcl_ml_min=130&heart_rate_bpm=65&sex=male&signs_of_chf=false&prior_vascular_disease=false&diabetes=false&systolic_mm_hg=140

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge. 

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/crusade?hematocrit_percent=42&crcl_ml_min=130&heart_rate_bpm=65&sex=male&signs_of_chf=false&prior_vascular_disease=false&diabetes=false&systolic_mm_hg=140"

Parameters

Name Type Required Description
hematocrit_percent number required Hematocrit percent (10-70). Subherwal 2009 Table 4: <31 → 9; 31–<34 → 7; 34–<37 → 3; 37–<40 → 2; ≥40 → 0.
crcl_ml_min number required Creatinine clearance in mL/min (1-300), Cockcroft–Gault as assigned by the caller. magent does not compute Cockcroft–Gault. Table 4: ≤15 → 39; >15–30 → 35; >30–60 → 28; >60–90 → 17; >90–120 → 7; >120 → 0.
heart_rate_bpm integer required Heart rate in beats per minute (integer 30-220). Table 4: ≤70 → 0; 71–80 → 1; 81–90 → 3; 91–100 → 6; 101–110 → 8; 111–120 → 10; ≥121 → 11.
sex string required Sex (female or male). Female scores 8; male scores 0.
signs_of_chf boolean required Signs of CHF at presentation as assigned by the caller. true or false. 7 points if true. magent does not examine the patient.
prior_vascular_disease boolean required Prior vascular disease (PAD or prior stroke) as assigned by the caller. true or false. 6 points if true.
diabetes boolean required Diabetes mellitus as assigned by the caller. true or false. 6 points if true.
systolic_mm_hg number required Systolic blood pressure in mm Hg (50-250). Table 4 is non-monotonic: ≤90 → 10; 91–100 → 8; 101–120 → 5; 121–180 → 1; 181–200 → 3; ≥201 → 5.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/crusade Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "crcl_ml_min": "130",
      "diabetes": "false",
      "heart_rate_bpm": "65",
      "hematocrit_percent": "42",
      "prior_vascular_disease": "false",
      "sex": "male",
      "signs_of_chf": "false",
      "systolic_mm_hg": "140"
    },
    {
      "crcl_ml_min": "130",
      "diabetes": "false",
      "heart_rate_bpm": "65",
      "hematocrit_percent": "42",
      "prior_vascular_disease": "false",
      "sex": "male",
      "signs_of_chf": "false",
      "systolic_mm_hg": "140"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/crusade",
  "items": [
    {
      "components": [
        {
          "value": 42.0,
          "factor": "hematocrit_percent",
          "points": 0,
          "present": false
        },
        {
          "value": 130.0,
          "factor": "crcl_ml_min",
          "points": 0,
          "present": false
        },
        {
          "value": 65,
          "factor": "heart_rate_bpm",
          "points": 0,
          "present": false
        },
        {
          "value": "male",
          "factor": "sex",
          "points": 0,
          "present": false
        },
        {
          "factor": "signs_of_chf",
          "points": 0,
          "present": false
        },
        {
          "factor": "prior_vascular_disease",
          "points": 0,
          "present": false
        },
        {
          "factor": "diabetes",
          "points": 0,
          "present": false
        },
        {
          "value": 140.0,
          "factor": "systolic_mm_hg",
          "points": 1,
          "present": true
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Subherwal S, Bach RG, Chen AY, et al.",
        "doi": "10.1161/CIRCULATIONAHA.108.828541",
        "id": "subherwal-2009",
        "pmid": "19332461",
        "source": "Circulation. 2009;119(14):1873-1882",
        "title": "Baseline risk of major bleeding in non–ST-segment-elevation myocardial infarction: the CRUSADE Bleeding Score"
      },
      "formula": "crusade",
      "formula_expression": "CRUSADE = hematocrit(<31:9, 31-<34:7, 34-<37:3, 37-<40:2, >=40:0) + crcl_ml_min(<=15:39, >15-30:35, >30-60:28, >60-90:17, >90-120:7, >120:0) + heart_rate(<=70:0, 71-80:1, 81-90:3, 91-100:6, 101-110:8, 111-120:10, >=121:11) + female(8) + signs_of_chf(7) + prior_vascular_disease(6) + diabetes(6) + systolic(<=90:10, 91-100:8, 101-120:5, 121-180:1, 181-200:3, >=201:5); Subherwal 2009 Table 4; quintiles <=20 3.1%, 21-30 5.5%, 31-40 8.6%, 41-50 11.9%, >50 19.5%; max 96",
      "systolic_mm_hg": 140.0,
      "max_score": 96,
      "score": 1,
      "sex": "male",
      "heart_rate_bpm": 65,
      "crcl_ml_min": 130.0,
      "crusade_band": "very_low",
      "diabetes": false,
      "hematocrit_percent": 42.0,
      "in_hospital_major_bleeding_percent": 3.1,
      "prior_vascular_disease": false,
      "signs_of_chf": false
    },
    {
      "components": [
        {
          "value": 42.0,
          "factor": "hematocrit_percent",
          "points": 0,
          "present": false
        },
        {
          "value": 130.0,
          "factor": "crcl_ml_min",
          "points": 0,
          "present": false
        },
        {
          "value": 65,
          "factor": "heart_rate_bpm",
          "points": 0,
          "present": false
        },
        {
          "value": "male",
          "factor": "sex",
          "points": 0,
          "present": false
        },
        {
          "factor": "signs_of_chf",
          "points": 0,
          "present": false
        },
        {
          "factor": "prior_vascular_disease",
          "points": 0,
          "present": false
        },
        {
          "factor": "diabetes",
          "points": 0,
          "present": false
        },
        {
          "value": 140.0,
          "factor": "systolic_mm_hg",
          "points": 1,
          "present": true
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Subherwal S, Bach RG, Chen AY, et al.",
        "doi": "10.1161/CIRCULATIONAHA.108.828541",
        "id": "subherwal-2009",
        "pmid": "19332461",
        "source": "Circulation. 2009;119(14):1873-1882",
        "title": "Baseline risk of major bleeding in non–ST-segment-elevation myocardial infarction: the CRUSADE Bleeding Score"
      },
      "formula": "crusade",
      "formula_expression": "CRUSADE = hematocrit(<31:9, 31-<34:7, 34-<37:3, 37-<40:2, >=40:0) + crcl_ml_min(<=15:39, >15-30:35, >30-60:28, >60-90:17, >90-120:7, >120:0) + heart_rate(<=70:0, 71-80:1, 81-90:3, 91-100:6, 101-110:8, 111-120:10, >=121:11) + female(8) + signs_of_chf(7) + prior_vascular_disease(6) + diabetes(6) + systolic(<=90:10, 91-100:8, 101-120:5, 121-180:1, 181-200:3, >=201:5); Subherwal 2009 Table 4; quintiles <=20 3.1%, 21-30 5.5%, 31-40 8.6%, 41-50 11.9%, >50 19.5%; max 96",
      "systolic_mm_hg": 140.0,
      "max_score": 96,
      "score": 1,
      "sex": "male",
      "heart_rate_bpm": 65,
      "crcl_ml_min": 130.0,
      "crusade_band": "very_low",
      "diabetes": false,
      "hematocrit_percent": 42.0,
      "in_hospital_major_bleeding_percent": 3.1,
      "prior_vascular_disease": false,
      "signs_of_chf": false
    }
  ]
}

Response

Field Type Description
formula string crusade
formula_expression string Exact expression used
score integer Table 4 point total (integer, max 96)
max_score integer Always 96 (sum of Table 4 maxima)
crusade_band string very_low (≤20), low (21-30), moderate (31-40), high (41-50), or very_high (>50)
in_hospital_major_bleeding_percent number Published in-hospital major bleeding percent for the quintile: 3.1, 5.5, 8.6, 11.9, or 19.5
hematocrit_percent number Hematocrit percent used
crcl_ml_min number Caller-assigned Cockcroft–Gault creatinine clearance, mL/min
heart_rate_bpm integer Heart rate used, beats per minute
sex string female or male
signs_of_chf boolean Caller-assigned signs of CHF at presentation
prior_vascular_disease boolean Caller-assigned prior vascular disease (PAD or prior stroke)
diabetes boolean Caller-assigned diabetes mellitus
systolic_mm_hg number Systolic BP used, mm Hg
components array Per-factor Table 4 points
citation object Subherwal 2009 citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup. 

{
  "components": [
    {
      "value": 42.0,
      "factor": "hematocrit_percent",
      "points": 0,
      "present": false
    },
    {
      "value": 130.0,
      "factor": "crcl_ml_min",
      "points": 0,
      "present": false
    },
    {
      "value": 65,
      "factor": "heart_rate_bpm",
      "points": 0,
      "present": false
    },
    {
      "value": "male",
      "factor": "sex",
      "points": 0,
      "present": false
    },
    {
      "factor": "signs_of_chf",
      "points": 0,
      "present": false
    },
    {
      "factor": "prior_vascular_disease",
      "points": 0,
      "present": false
    },
    {
      "factor": "diabetes",
      "points": 0,
      "present": false
    },
    {
      "value": 140.0,
      "factor": "systolic_mm_hg",
      "points": 1,
      "present": true
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Subherwal S, Bach RG, Chen AY, et al.",
    "doi": "10.1161/CIRCULATIONAHA.108.828541",
    "id": "subherwal-2009",
    "pmid": "19332461",
    "source": "Circulation. 2009;119(14):1873-1882",
    "title": "Baseline risk of major bleeding in non–ST-segment-elevation myocardial infarction: the CRUSADE Bleeding Score"
  },
  "formula": "crusade",
  "formula_expression": "CRUSADE = hematocrit(<31:9, 31-<34:7, 34-<37:3, 37-<40:2, >=40:0) + crcl_ml_min(<=15:39, >15-30:35, >30-60:28, >60-90:17, >90-120:7, >120:0) + heart_rate(<=70:0, 71-80:1, 81-90:3, 91-100:6, 101-110:8, 111-120:10, >=121:11) + female(8) + signs_of_chf(7) + prior_vascular_disease(6) + diabetes(6) + systolic(<=90:10, 91-100:8, 101-120:5, 121-180:1, 181-200:3, >=201:5); Subherwal 2009 Table 4; quintiles <=20 3.1%, 21-30 5.5%, 31-40 8.6%, 41-50 11.9%, >50 19.5%; max 96",
  "systolic_mm_hg": 140.0,
  "max_score": 96,
  "score": 1,
  "sex": "male",
  "heart_rate_bpm": 65,
  "crcl_ml_min": 130.0,
  "crusade_band": "very_low",
  "diabetes": false,
  "hematocrit_percent": 42.0,
  "in_hospital_major_bleeding_percent": 3.1,
  "prior_vascular_disease": false,
  "signs_of_chf": false
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_hematocrit hematocrit_percent must be a number from 10 to 70. Returned before settlement; you are not charged.
400 invalid_crcl crcl_ml_min must be a number from 1 to 300 (Cockcroft-Gault mL/min as assigned by the caller). Returned before settlement; you are not charged.
400 invalid_heart_rate heart_rate_bpm must be an integer from 30 to 220 Returned before settlement; you are not charged.
400 invalid_sex sex must be female or male Returned before settlement; you are not charged.
400 invalid_flag boolean clinical flags must be true or false Returned before settlement; you are not charged.
400 invalid_systolic_bp systolic_mm_hg or systolic_bp_mm_hg must be a number from 50 to 250. Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • TIMI UA/NSTEMI — Compute the TIMI risk score for unstable angina / NSTEMI from age and six caller-assigned flags.
  • HEART score — Compute the HEART score as age points plus caller-assigned history, ECG, risk factors, and troponin (each 0-2).
  • Killip — Return the Killip and Kimball 1967 myocardial-infarction heart-failure class 1-4 from a caller-assigned integer, with the published class description and 1967 CCU hospital mortality.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.