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DAS28-ESR (Prevoo 1995)

DAS28-ESR

Compute the Prevoo 1995 28-joint DAS with ESR from caller-assigned tender and swollen 28-joint counts, ESR in mm/h, and patient general health on a 0-100 mm VAS. Returns the published score only.

LIVE $0.005 USDC GET /api/calc/das28_esr

Markdown: /docs/das28-esr.md · Canonical: https://magentlab.com/docs/das28-esr

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Prevoo 1995 28-joint DAS with ESR from caller-assigned tender and swollen 28-joint counts, ESR in mm/h, and patient general health on a 0-100 mm VAS. Returns the published score only.

When to use

When an agent already has 28-joint tender and swollen counts, ESR in mm/h, and a 0-100 mm patient global and needs the Prevoo 1995 DAS28-ESR arithmetic, not SDAI, not CDAI, not DAS28-CRP, and not later EULAR 2.6/3.2/5.1 cutoffs.

When not to use

• Not a medical device and not a rheumatoid arthritis diagnosis or a treatment order.
• magent does not count joints or assay ESR. tjc28, sjc28, esr_mm_h, and gh are caller-assigned. GH is millimetres on a 0-100 VAS, not 0-10 cm CDAI/SDAI.
• Prevoo 1995 publishes this 28-joint DAS and discriminates high vs low activity by rheumatologist decision. It does not publish the later EULAR 2.6 / 3.2 / 5.1 cutoffs. magent returns the score only.
• Not SDAI. Not CDAI. Not DAS28-CRP.

Formula

DAS28-ESR = 0.56*sqrt(tjc28) + 0.28*sqrt(sjc28) + 0.70*ln(esr_mm_h) + 0.014*gh; Prevoo 1995; TJC28 and SJC28 integers 0-28; ESR mm/h strictly >0 (typical 1-150, natural log); GH 0-100 mm VAS (not 0-10 CDAI/SDAI); magent does not count joints or assay ESR; no EULAR 2.6/3.2/5.1 cutoffs

Citation

Title

Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

Authors

Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL

Source

Arthritis Rheum. 1995;38(1):44-48

DOI

10.1002/art.1780380107

Worked example

Also searched as

• DAS28-ESR
• 28-joint disease activity score ESR
• Prevoo DAS28
• DAS28 erythrocyte sedimentation rate
• RA DAS28 ESR
• modified DAS 28-joint

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/das28_esr?tjc28=0&sjc28=0&esr_mm_h=10&gh=0

Full URL: https://api.magentlab.com/api/calc/das28_esr?tjc28=0&sjc28=0&esr_mm_h=10&gh=0

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/das28_esr?tjc28=0&sjc28=0&esr_mm_h=10&gh=0"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/das28_esr Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "esr_mm_h": "10",
      "gh": "0",
      "sjc28": "0",
      "tjc28": "0"
    },
    {
      "esr_mm_h": "10",
      "gh": "0",
      "sjc28": "0",
      "tjc28": "0"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/das28_esr",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL",
        "doi": "10.1002/art.1780380107",
        "id": "prevoo-1995",
        "pmid": "7818570",
        "source": "Arthritis Rheum. 1995;38(1):44-48",
        "title": "Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis"
      },
      "formula": "das28_esr",
      "formula_expression": "DAS28-ESR = 0.56*sqrt(tjc28) + 0.28*sqrt(sjc28) + 0.70*ln(esr_mm_h) + 0.014*gh; Prevoo 1995; TJC28 and SJC28 integers 0-28; ESR mm/h strictly >0 (typical 1-150, natural log); GH 0-100 mm VAS (not 0-10 CDAI/SDAI); magent does not count joints or assay ESR; no EULAR 2.6/3.2/5.1 cutoffs",
      "score": 1.6118,
      "sjc28": 0,
      "tjc28": 0,
      "gh": 0.0,
      "esr_mm_h": 10.0
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL",
        "doi": "10.1002/art.1780380107",
        "id": "prevoo-1995",
        "pmid": "7818570",
        "source": "Arthritis Rheum. 1995;38(1):44-48",
        "title": "Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis"
      },
      "formula": "das28_esr",
      "formula_expression": "DAS28-ESR = 0.56*sqrt(tjc28) + 0.28*sqrt(sjc28) + 0.70*ln(esr_mm_h) + 0.014*gh; Prevoo 1995; TJC28 and SJC28 integers 0-28; ESR mm/h strictly >0 (typical 1-150, natural log); GH 0-100 mm VAS (not 0-10 CDAI/SDAI); magent does not count joints or assay ESR; no EULAR 2.6/3.2/5.1 cutoffs",
      "score": 1.6118,
      "sjc28": 0,
      "tjc28": 0,
      "gh": 0.0,
      "esr_mm_h": 10.0
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL",
    "doi": "10.1002/art.1780380107",
    "id": "prevoo-1995",
    "pmid": "7818570",
    "source": "Arthritis Rheum. 1995;38(1):44-48",
    "title": "Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis"
  },
  "formula": "das28_esr",
  "formula_expression": "DAS28-ESR = 0.56*sqrt(tjc28) + 0.28*sqrt(sjc28) + 0.70*ln(esr_mm_h) + 0.014*gh; Prevoo 1995; TJC28 and SJC28 integers 0-28; ESR mm/h strictly >0 (typical 1-150, natural log); GH 0-100 mm VAS (not 0-10 CDAI/SDAI); magent does not count joints or assay ESR; no EULAR 2.6/3.2/5.1 cutoffs",
  "score": 1.6118,
  "sjc28": 0,
  "tjc28": 0,
  "gh": 0.0,
  "esr_mm_h": 10.0
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• CDAI-RA — Sum caller-assigned 28-joint swollen and tender counts and 0–10 cm patient and evaluator globals and return the Aletaha 2005 Clinical Disease Activity Index. Does not add CRP and does not return activity-state cutoffs.
• SDAI — Sum caller-assigned 28-joint swollen and tender counts, 0–10 cm patient and evaluator globals, and CRP in mg/dL, and return the Aletaha 2005 SDAI with the newly proposed activity state.
• ACR/EULAR RA — Apply the 2010 ACR/EULAR rheumatoid arthritis classification criteria (Aletaha Table 3): require definite clinical synovitis, sum joint involvement, serology, acute-phase reactants, and symptom duration (max 10), and return whether score ≥6 or typical RA erosions classify RA. Not a diagnosis.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.