Kidney · LIVE
Kt/V
Compute the Daugirdas 1993 second-generation logarithmic single-pool variable-volume Kt/V from pre- and post-dialysis BUN, session length, ultrafiltration volume, and post-dialysis weight.
Markdown: /docs/kt-v.md · Canonical: https://magentlab.com/docs/kt-v
Not a medical device. Not a diagnosis, dose, or listing recommendation.
What it computes
Compute the Daugirdas 1993 second-generation logarithmic single-pool variable-volume Kt/V from pre- and post-dialysis BUN, session length, ultrafiltration volume, and post-dialysis weight.
When to use
When an agent needs the published 1993 logarithmic Kt/V and must not invent adequacy targets, substitute equilibrated eKt/V or stdKt/V, or compute a urea reduction ratio.
When not to use
- Not a medical device.
- Not a dialysis prescription.
- Daugirdas 1993 second-generation single-pool variable-volume Kt/V only. This is not equilibrated eKt/V, not stdKt/V, and not a urea-reduction-ratio tool.
- Does not assign KDOQI or other adequacy targets. Those cuts are not in Daugirdas 1993.
- Weight is post-dialysis body weight (W). magent does not estimate urea distribution volume.
Formula
Kt/V = -ln(R - 0.008 * t) + (4 - 3.5 * R) * UF / W
Citation
- Title
- Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error
- Authors
- Daugirdas JT
- Source
- J Am Soc Nephrol. 1993;4(5):1205-1213
Worked example
Pre BUN 80, post BUN 24, 4 h, UF 2 L, 70 kg
Given:
post_bun_mg_dl=24pre_bun_mg_dl=80session_hours=4uf_l=2weight_kg=70
- R = 24 / 80 = 0.3
- R - 0.008 * 4 = 0.268
- -ln(0.268) ≈ 1.3172
- (4 - 3.5 * 0.3) * 2 / 70 ≈ 0.0843
- round to 2 decimals → 1.40
Also searched as
- Kt/V
- Daugirdas Kt/V
- single-pool Kt/V
- spKt/V
- hemodialysis Kt/V
- variable-volume Kt/V
- Daugirdas 1993 Kt/V
- urea kinetic Kt/V
Try
Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.
/api/calc/kt_v?pre_bun_mg_dl=80&post_bun_mg_dl=24&session_hours=4&uf_l=2&weight_kg=70
Full URL: https://api.magentlab.com/api/calc/kt_v?pre_bun_mg_dl=80&post_bun_mg_dl=24&session_hours=4&uf_l=2&weight_kg=70
Call
Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params
return HTTP 400 before any quote or charge.
curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/kt_v?pre_bun_mg_dl=80&post_bun_mg_dl=24&session_hours=4&uf_l=2&weight_kg=70"
Parameters
| Name | Type | Required | Description |
|---|---|---|---|
pre_bun_mg_dl |
number | required | Predialysis blood urea nitrogen in mg/dL (1-200). Required with post_bun_mg_dl. |
post_bun_mg_dl |
number | required | Postdialysis blood urea nitrogen in mg/dL (1-200). Required with pre_bun_mg_dl. |
session_hours |
number | required | Hemodialysis session length in hours (1.0-8.0). Daugirdas 1993 t. |
uf_l |
number | required | Ultrafiltration volume in litres (0-15). Daugirdas 1993 UF. |
weight_kg |
number | optional | Post-dialysis body weight in kilograms (1-500). Provide weight_kg or weight_lb, not both. |
weight_lb |
number | optional | Post-dialysis body weight in pounds (2-1100). Converted as kg = lb × 0.45359237. Provide weight_kg or weight_lb, not both. |
Bulk (POST)
POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.
- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.
Example request (fixture)
{
"items": [
{
"post_bun_mg_dl": "24",
"pre_bun_mg_dl": "80",
"session_hours": "4",
"uf_l": "2",
"weight_kg": "70"
},
{
"post_bun_mg_dl": "24",
"pre_bun_mg_dl": "80",
"session_hours": "4",
"uf_l": "2",
"weight_kg": "70"
}
]
}
Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.
Example 200 (fixture)
{
"count": 2,
"path": "/api/calc/kt_v",
"items": [
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Daugirdas JT",
"doi": "10.1681/ASN.V451205",
"id": "daugirdas-1993",
"pmid": "8305648",
"source": "J Am Soc Nephrol. 1993;4(5):1205-1213",
"title": "Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error"
},
"formula": "daugirdas_1993",
"formula_expression": "Kt/V = -ln(R - 0.008 * t) + (4 - 3.5 * R) * UF / W",
"weight_kg": 70.0,
"kt_v": 1.4,
"post_bun_mg_dl": 24.0,
"pre_bun_mg_dl": 80.0,
"session_hours": 4.0,
"uf_l": 2.0
},
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Daugirdas JT",
"doi": "10.1681/ASN.V451205",
"id": "daugirdas-1993",
"pmid": "8305648",
"source": "J Am Soc Nephrol. 1993;4(5):1205-1213",
"title": "Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error"
},
"formula": "daugirdas_1993",
"formula_expression": "Kt/V = -ln(R - 0.008 * t) + (4 - 3.5 * R) * UF / W",
"weight_kg": 70.0,
"kt_v": 1.4,
"post_bun_mg_dl": 24.0,
"pre_bun_mg_dl": 80.0,
"session_hours": 4.0,
"uf_l": 2.0
}
]
}
Response
| Field | Type | Description |
|---|---|---|
formula |
string | daugirdas_1993 |
formula_expression |
string | Exact expression used |
pre_bun_mg_dl |
number | Predialysis BUN used in mg/dL |
post_bun_mg_dl |
number | Postdialysis BUN used in mg/dL |
session_hours |
number | Session length used in hours |
uf_l |
number | Ultrafiltration volume used in litres |
weight_kg |
number | Post-dialysis body weight used in kg (after conversion) |
kt_v |
number | Daugirdas 1993 single-pool variable-volume Kt/V, 2 decimals |
citation |
object | Daugirdas 1993 citation |
disclaimer |
string | Not-a-device notice |
Example JSON
Machine form of the same example. Frozen fixture. Not a live lookup.
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Daugirdas JT",
"doi": "10.1681/ASN.V451205",
"id": "daugirdas-1993",
"pmid": "8305648",
"source": "J Am Soc Nephrol. 1993;4(5):1205-1213",
"title": "Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error"
},
"formula": "daugirdas_1993",
"formula_expression": "Kt/V = -ln(R - 0.008 * t) + (4 - 3.5 * R) * UF / W",
"weight_kg": 70.0,
"kt_v": 1.4,
"post_bun_mg_dl": 24.0,
"pre_bun_mg_dl": 80.0,
"session_hours": 4.0,
"uf_l": 2.0
}
Client errors (HTTP 400)
Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.
| HTTP | Code | When |
|---|---|---|
| 400 | invalid_bun |
bun_mg_dl must be a number from 1 to 200. Returned before settlement; you are not charged. |
| 400 | invalid_dialysis_hours |
session_hours must be a number from 1.0 to 8.0 (Daugirdas 1993). Returned before settlement; you are not charged. |
| 400 | invalid_ultrafiltration |
uf_l must be a number from 0 to 15 (Daugirdas 1993 ultrafiltration volume in litres). Returned before settlement; you are not charged. |
| 400 | invalid_weight |
weight_kg (1-500) or weight_lb (2-1100) is required Returned before settlement; you are not charged. |
| 400 | invalid_urea_ratio |
post_bun_mg_dl must be < pre_bun_mg_dl and R - 0.008 * t must be > 0 (Daugirdas 1993). Returned before settlement; you are not charged. |
| 400 | invalid_items |
POST body must be a JSON object with only an items array Returned before settlement; you are not charged. |
| 400 | invalid_item_count |
items must be an array of 1 to 25 objects Returned before settlement; you are not charged. |
| 400 | invalid_item |
each items entry must be a JSON object Returned before settlement; you are not charged. |
Related tools
- CKD-EPI 2021 eGFR — Compute race-free CKD-EPI 2021 creatinine eGFR in mL/min/1.73m2.
- Cockcroft–Gault CrCl — Compute Cockcroft–Gault creatinine clearance in mL/min using total body weight.
Payment
Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64
PAYMENT-REQUIRED
header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake
and shared payment errors: Payments.
Stdio MCP: /docs/mcp.
Guarantees
- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.