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Kt/V

Compute the Daugirdas 1993 second-generation logarithmic single-pool variable-volume Kt/V from pre- and post-dialysis BUN, session length, ultrafiltration volume, and post-dialysis weight.

LIVE $0.005 USDC GET /api/calc/kt_v

Markdown: /docs/kt-v.md · Canonical: https://magentlab.com/docs/kt-v

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Daugirdas 1993 second-generation logarithmic single-pool variable-volume Kt/V from pre- and post-dialysis BUN, session length, ultrafiltration volume, and post-dialysis weight.

When to use

When an agent needs the published 1993 logarithmic Kt/V and must not invent adequacy targets, substitute equilibrated eKt/V or stdKt/V, or compute a urea reduction ratio.

When not to use

  • Not a medical device.
  • Not a dialysis prescription.
  • Daugirdas 1993 second-generation single-pool variable-volume Kt/V only. This is not equilibrated eKt/V, not stdKt/V, and not a urea-reduction-ratio tool.
  • Does not assign KDOQI or other adequacy targets. Those cuts are not in Daugirdas 1993.
  • Weight is post-dialysis body weight (W). magent does not estimate urea distribution volume.

Formula

Kt/V = -ln(R - 0.008 * t) + (4 - 3.5 * R) * UF / W

Citation

Title
Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error
Authors
Daugirdas JT
Source
J Am Soc Nephrol. 1993;4(5):1205-1213
DOI
10.1681/ASN.V451205

Worked example

Pre BUN 80, post BUN 24, 4 h, UF 2 L, 70 kg

Given: post_bun_mg_dl=24pre_bun_mg_dl=80session_hours=4uf_l=2weight_kg=70

  1. R = 24 / 80 = 0.3
  2. R - 0.008 * 4 = 0.268
  3. -ln(0.268) ≈ 1.3172
  4. (4 - 3.5 * 0.3) * 2 / 70 ≈ 0.0843
  5. round to 2 decimals → 1.40

Also searched as

  • Kt/V
  • Daugirdas Kt/V
  • single-pool Kt/V
  • spKt/V
  • hemodialysis Kt/V
  • variable-volume Kt/V
  • Daugirdas 1993 Kt/V
  • urea kinetic Kt/V

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/kt_v?pre_bun_mg_dl=80&post_bun_mg_dl=24&session_hours=4&uf_l=2&weight_kg=70

Full URL: https://api.magentlab.com/api/calc/kt_v?pre_bun_mg_dl=80&post_bun_mg_dl=24&session_hours=4&uf_l=2&weight_kg=70

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/kt_v?pre_bun_mg_dl=80&post_bun_mg_dl=24&session_hours=4&uf_l=2&weight_kg=70"

Parameters

Name Type Required Description
pre_bun_mg_dl number required Predialysis blood urea nitrogen in mg/dL (1-200). Required with post_bun_mg_dl.
post_bun_mg_dl number required Postdialysis blood urea nitrogen in mg/dL (1-200). Required with pre_bun_mg_dl.
session_hours number required Hemodialysis session length in hours (1.0-8.0). Daugirdas 1993 t.
uf_l number required Ultrafiltration volume in litres (0-15). Daugirdas 1993 UF.
weight_kg number optional Post-dialysis body weight in kilograms (1-500). Provide weight_kg or weight_lb, not both.
weight_lb number optional Post-dialysis body weight in pounds (2-1100). Converted as kg = lb × 0.45359237. Provide weight_kg or weight_lb, not both.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/kt_v Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "post_bun_mg_dl": "24",
      "pre_bun_mg_dl": "80",
      "session_hours": "4",
      "uf_l": "2",
      "weight_kg": "70"
    },
    {
      "post_bun_mg_dl": "24",
      "pre_bun_mg_dl": "80",
      "session_hours": "4",
      "uf_l": "2",
      "weight_kg": "70"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/kt_v",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Daugirdas JT",
        "doi": "10.1681/ASN.V451205",
        "id": "daugirdas-1993",
        "pmid": "8305648",
        "source": "J Am Soc Nephrol. 1993;4(5):1205-1213",
        "title": "Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error"
      },
      "formula": "daugirdas_1993",
      "formula_expression": "Kt/V = -ln(R - 0.008 * t) + (4 - 3.5 * R) * UF / W",
      "weight_kg": 70.0,
      "kt_v": 1.4,
      "post_bun_mg_dl": 24.0,
      "pre_bun_mg_dl": 80.0,
      "session_hours": 4.0,
      "uf_l": 2.0
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Daugirdas JT",
        "doi": "10.1681/ASN.V451205",
        "id": "daugirdas-1993",
        "pmid": "8305648",
        "source": "J Am Soc Nephrol. 1993;4(5):1205-1213",
        "title": "Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error"
      },
      "formula": "daugirdas_1993",
      "formula_expression": "Kt/V = -ln(R - 0.008 * t) + (4 - 3.5 * R) * UF / W",
      "weight_kg": 70.0,
      "kt_v": 1.4,
      "post_bun_mg_dl": 24.0,
      "pre_bun_mg_dl": 80.0,
      "session_hours": 4.0,
      "uf_l": 2.0
    }
  ]
}

Response

Field Type Description
formula string daugirdas_1993
formula_expression string Exact expression used
pre_bun_mg_dl number Predialysis BUN used in mg/dL
post_bun_mg_dl number Postdialysis BUN used in mg/dL
session_hours number Session length used in hours
uf_l number Ultrafiltration volume used in litres
weight_kg number Post-dialysis body weight used in kg (after conversion)
kt_v number Daugirdas 1993 single-pool variable-volume Kt/V, 2 decimals
citation object Daugirdas 1993 citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Daugirdas JT",
    "doi": "10.1681/ASN.V451205",
    "id": "daugirdas-1993",
    "pmid": "8305648",
    "source": "J Am Soc Nephrol. 1993;4(5):1205-1213",
    "title": "Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error"
  },
  "formula": "daugirdas_1993",
  "formula_expression": "Kt/V = -ln(R - 0.008 * t) + (4 - 3.5 * R) * UF / W",
  "weight_kg": 70.0,
  "kt_v": 1.4,
  "post_bun_mg_dl": 24.0,
  "pre_bun_mg_dl": 80.0,
  "session_hours": 4.0,
  "uf_l": 2.0
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_bun bun_mg_dl must be a number from 1 to 200. Returned before settlement; you are not charged.
400 invalid_dialysis_hours session_hours must be a number from 1.0 to 8.0 (Daugirdas 1993). Returned before settlement; you are not charged.
400 invalid_ultrafiltration uf_l must be a number from 0 to 15 (Daugirdas 1993 ultrafiltration volume in litres). Returned before settlement; you are not charged.
400 invalid_weight weight_kg (1-500) or weight_lb (2-1100) is required Returned before settlement; you are not charged.
400 invalid_urea_ratio post_bun_mg_dl must be < pre_bun_mg_dl and R - 0.008 * t must be > 0 (Daugirdas 1993). Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

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Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.