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Light's criteria (pleural fluid)
Light's criteria
Apply Light 1972 pleural fluid criteria from protein ratio, LDH ratio, and pleural LDH versus two-thirds the laboratory LDH upper limit of normal.
Also searched as
- Light's criteria
- Light criteria pleural
- transudate vs exudate
- pleural fluid LDH
- pleural protein ratio
- Light 1972 effusion
Markdown: /docs/lights.md · Canonical: https://magentlab.com/docs/lights
Not a medical device. Not a diagnosis, dose, or listing recommendation.
What it computes
Apply Light 1972 pleural fluid criteria from protein ratio, LDH ratio, and pleural LDH versus two-thirds the laboratory LDH upper limit of normal.
When to use
When an agent needs Light 1972 transudate versus exudate arithmetic and must not invent Heffner abbreviated criteria, an NT-proBNP rule, or a cause of the effusion.
When not to use
- Not a diagnosis of the cause of an effusion (for example CHF versus infection).
- Not Heffner's abbreviated two-test criteria and not an NT-proBNP rule.
- magent does not interpret a chest x-ray.
- ldh_uln_u_l is required; magent does not assume a laboratory ULN of 200 U/L.
- Cutoffs are strictly greater than 0.5, 0.6, and two-thirds ULN (equality is not exudate by that criterion).
Formula
exudate if pleural_protein_g_dl / serum_protein_g_dl > 0.5 or pleural_ldh_u_l / serum_ldh_u_l > 0.6 or pleural_ldh_u_l > (2/3) * ldh_uln_u_l
Citation
- Authors
- Light RW, Macgregor MI, Luchsinger PC, Ball WC Jr
- Source
- Ann Intern Med. 1972;77(4):507-513
Worked example
Protein 3.0/6.0, LDH 100/200, ULN 200 — transudate
Given:
ldh_uln_u_l=200pleural_ldh_u_l=100pleural_protein_g_dl=3.0serum_ldh_u_l=200serum_protein_g_dl=6.0
- protein_ratio = 3.0 / 6.0 = 0.5 (not > 0.5)
- ldh_ratio = 100 / 200 = 0.5 (not > 0.6)
- ldh_two_thirds_uln = (2/3) × 200 = 133.3; pleural LDH 100 is not > 133.3
- no criterion met → transudate
Protein 4.0/6.0 — exudate by protein ratio
Given:
ldh_uln_u_l=200pleural_ldh_u_l=100pleural_protein_g_dl=4.0serum_ldh_u_l=200serum_protein_g_dl=6.0
- protein_ratio = 4.0 / 6.0 = 0.667 (> 0.5)
- any one criterion met → exudate
Try
Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.
Full URL: https://api.magentlab.com/api/calc/lights?pleural_protein_g_dl=3.0&serum_protein_g_dl=6.0&pleural_ldh_u_l=100&serum_ldh_u_l=200&ldh_uln_u_l=200
Call
Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params
return HTTP 400 before any quote or charge.
curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/lights?pleural_protein_g_dl=3.0&serum_protein_g_dl=6.0&pleural_ldh_u_l=100&serum_ldh_u_l=200&ldh_uln_u_l=200"
Parameters
| Name | Type | Required | Description |
|---|---|---|---|
pleural_protein_g_dl |
number | required | Pleural fluid protein in g/dL (0.1-20). |
serum_protein_g_dl |
number | required | Serum protein in g/dL (0.1-20). |
pleural_ldh_u_l |
number | required | Pleural fluid LDH in U/L (1-10000). |
serum_ldh_u_l |
number | required | Serum LDH in U/L (1-10000). |
ldh_uln_u_l |
number | required | Laboratory LDH upper limit of normal in U/L (50-2000). Required; magent does not assume 200. |
Bulk (POST)
POST the same path with a JSON items array. Price is n times the GET unit. Invalid items return HTTP 400 before settlement.
- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.
Example request (fixture)
{
"items": [
{
"ldh_uln_u_l": "200",
"pleural_ldh_u_l": "100",
"pleural_protein_g_dl": "3.0",
"serum_ldh_u_l": "200",
"serum_protein_g_dl": "6.0"
},
{
"ldh_uln_u_l": "200",
"pleural_ldh_u_l": "100",
"pleural_protein_g_dl": "3.0",
"serum_ldh_u_l": "200",
"serum_protein_g_dl": "6.0"
}
]
}
Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.
Example 200 (fixture)
{
"count": 2,
"path": "/api/calc/lights",
"items": [
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Light RW, Macgregor MI, Luchsinger PC, Ball WC Jr",
"doi": "10.7326/0003-4819-77-4-507",
"id": "light-1972",
"source": "Ann Intern Med. 1972;77(4):507-513",
"title": "Pleural effusions: the diagnostic separation of transudates and exudates"
},
"formula": "lights",
"formula_expression": "exudate if pleural_protein_g_dl / serum_protein_g_dl > 0.5 or pleural_ldh_u_l / serum_ldh_u_l > 0.6 or pleural_ldh_u_l > (2/3) * ldh_uln_u_l",
"criteria": [
{
"value": 0.5,
"factor": "protein_ratio_gt_0_5",
"met": false
},
{
"value": 0.5,
"factor": "ldh_ratio_gt_0_6",
"met": false
},
{
"value": 100.0,
"factor": "pleural_ldh_gt_two_thirds_uln",
"met": false
}
],
"exudate": false,
"ldh_ratio": 0.5,
"ldh_two_thirds_uln": 133.3,
"pleural_ldh_u_l": 100.0,
"protein_ratio": 0.5
},
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Light RW, Macgregor MI, Luchsinger PC, Ball WC Jr",
"doi": "10.7326/0003-4819-77-4-507",
"id": "light-1972",
"source": "Ann Intern Med. 1972;77(4):507-513",
"title": "Pleural effusions: the diagnostic separation of transudates and exudates"
},
"formula": "lights",
"formula_expression": "exudate if pleural_protein_g_dl / serum_protein_g_dl > 0.5 or pleural_ldh_u_l / serum_ldh_u_l > 0.6 or pleural_ldh_u_l > (2/3) * ldh_uln_u_l",
"criteria": [
{
"value": 0.5,
"factor": "protein_ratio_gt_0_5",
"met": false
},
{
"value": 0.5,
"factor": "ldh_ratio_gt_0_6",
"met": false
},
{
"value": 100.0,
"factor": "pleural_ldh_gt_two_thirds_uln",
"met": false
}
],
"exudate": false,
"ldh_ratio": 0.5,
"ldh_two_thirds_uln": 133.3,
"pleural_ldh_u_l": 100.0,
"protein_ratio": 0.5
}
]
}
Response
| Field | Type | Description |
|---|---|---|
formula |
string | lights |
formula_expression |
string | Exact expression used |
exudate |
boolean | true if any Light 1972 criterion is met (strictly greater than). Not a diagnosis of cause. |
protein_ratio |
number | pleural_protein_g_dl / serum_protein_g_dl, 3 decimals |
ldh_ratio |
number | pleural_ldh_u_l / serum_ldh_u_l, 3 decimals |
ldh_two_thirds_uln |
number | (2/3) × ldh_uln_u_l, 1 decimal |
pleural_ldh_u_l |
number | Pleural fluid LDH used, U/L |
criteria |
array | Three Light 1972 rows (protein_ratio_gt_0_5, ldh_ratio_gt_0_6, pleural_ldh_gt_two_thirds_uln), each with factor, met, and value |
citation |
object | Light et al. 1972 citation |
disclaimer |
string | Not-a-device notice |
Example JSON
Machine form of the same example. Frozen fixture. Not a live lookup.
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Light RW, Macgregor MI, Luchsinger PC, Ball WC Jr",
"doi": "10.7326/0003-4819-77-4-507",
"id": "light-1972",
"source": "Ann Intern Med. 1972;77(4):507-513",
"title": "Pleural effusions: the diagnostic separation of transudates and exudates"
},
"formula": "lights",
"formula_expression": "exudate if pleural_protein_g_dl / serum_protein_g_dl > 0.5 or pleural_ldh_u_l / serum_ldh_u_l > 0.6 or pleural_ldh_u_l > (2/3) * ldh_uln_u_l",
"criteria": [
{
"value": 0.5,
"factor": "protein_ratio_gt_0_5",
"met": false
},
{
"value": 0.5,
"factor": "ldh_ratio_gt_0_6",
"met": false
},
{
"value": 100.0,
"factor": "pleural_ldh_gt_two_thirds_uln",
"met": false
}
],
"exudate": false,
"ldh_ratio": 0.5,
"ldh_two_thirds_uln": 133.3,
"pleural_ldh_u_l": 100.0,
"protein_ratio": 0.5
}
Client errors (HTTP 400)
Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.
| HTTP | Code | When |
|---|---|---|
| 400 | invalid_pleural_protein |
pleural_protein_g_dl must be a number from 0.1 to 20. Returned before settlement; you are not charged. |
| 400 | invalid_serum_protein |
serum_protein_g_dl must be a number from 0.1 to 20. Returned before settlement; you are not charged. |
| 400 | invalid_pleural_ldh |
pleural_ldh_u_l must be a number from 1 to 10000. Returned before settlement; you are not charged. |
| 400 | invalid_serum_ldh |
serum_ldh_u_l must be a number from 1 to 10000. Returned before settlement; you are not charged. |
| 400 | invalid_ldh_uln |
ldh_uln_u_l must be a number from 50 to 2000. Returned before settlement; you are not charged. |
| 400 | invalid_items |
POST body must be a JSON object with only an items array Returned before settlement; you are not charged. |
| 400 | invalid_item_count |
items must be an array of 1 to 25 objects Returned before settlement; you are not charged. |
| 400 | invalid_item |
each items entry must be a JSON object Returned before settlement; you are not charged. |
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Payment
Required query parameters must be present and valid. Invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64
PAYMENT-REQUIRED
header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake
and shared payment errors: Payments.
Stdio MCP: /docs/mcp.
Guarantees
- Invalid query parameters return HTTP 400 before settlement. You are not charged.
- Settlement finishes before the tool executes (paymentFlow upfront). Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.