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Oxygenation index

Compute the oxygenation index from inspired oxygen fraction, mean airway pressure in cm H2O, and arterial PO2.

LIVE $0.005 USDC GET /api/calc/oxygenation_index

Markdown: /docs/oxygenation-index.md · Canonical: https://magentlab.com/docs/oxygenation-index

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the oxygenation index from inspired oxygen fraction, mean airway pressure in cm H2O, and arterial PO2.

When to use

When an agent needs FiO2 × mean airway pressure × 100 / PaO2 and must not invent an OI or an ECMO-initiation threshold.

When not to use

  • Not a diagnosis. This is FiO2 × mean airway pressure × 100 / PaO2; it is not an ECMO-initiation protocol.
  • Mean airway pressure is ventilator cm H2O, not blood-pressure MAP.
  • FiO2 is a fraction (0.21–1.0), not a percent.

Formula

oxygenation_index = fio2 * mean_airway_pressure_cm_h2o * 100 / pao2_mm_hg

Citation

Title
Extracorporeal membrane oxygenation in pediatric respiratory failure
Authors
Ortiz RM, Cilley RE, Bartlett RH
Source
Pediatr Clin North Am. 1987;34(1):39-46
DOI
10.1016/S0031-3955(16)36180-7

Worked example

FiO2 0.5, MAP 12 cm H2O, PaO2 80

Given: fio2=0.5mean_airway_pressure_cm_h2o=12pao2_mm_hg=80

  1. OI = 0.5 × 12 × 100 / 80 = 7.5

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/oxygenation_index?fio2=0.5&mean_airway_pressure_cm_h2o=12&pao2_mm_hg=80

Full URL: https://api.magentlab.com/api/calc/oxygenation_index?fio2=0.5&mean_airway_pressure_cm_h2o=12&pao2_mm_hg=80

x402 V2 curl

Expect HTTP 402 and a PAYMENT-REQUIRED header until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge. HTTP 503 after a signature: retry the same PAYMENT-SIGNATURE — that is not a new 402.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/oxygenation_index?fio2=0.5&mean_airway_pressure_cm_h2o=12&pao2_mm_hg=80"

Cursor mcp.json

Intended config for @magent/mcp. This is not npm @x402/fetch (a payment fetch wrapper).

{
  "mcpServers": {
    "magent": {
      "args": [
        "-y",
        "@magent/mcp"
      ],
      "command": "npx",
      "env": {
        "X402_PRIVATE_KEY": "0xYOUR_SPENDING_KEY"
      }
    }
  }
}

Parameters

Name Type Required Description
fio2 number required Inspired oxygen as a fraction (0.21-1.0), not a percent.
mean_airway_pressure_cm_h2o number required Mean airway pressure in cm H2O (4-45), not blood-pressure MAP.
pao2_mm_hg number required Arterial PO2 in mm Hg (20-700).

Bulk (POST)

POST the same path with a JSON items array. Price is n times the GET unit. Invalid items return HTTP 400 before settlement.

POST /api/calc/oxygenation_index Max 25 unit_amount * n PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "fio2": "0.5",
      "mean_airway_pressure_cm_h2o": "12",
      "pao2_mm_hg": "80"
    },
    {
      "fio2": "0.5",
      "mean_airway_pressure_cm_h2o": "12",
      "pao2_mm_hg": "80"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/oxygenation_index",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ortiz RM, Cilley RE, Bartlett RH",
        "doi": "10.1016/S0031-3955(16)36180-7",
        "id": "ortiz-bartlett-1987",
        "source": "Pediatr Clin North Am. 1987;34(1):39-46",
        "title": "Extracorporeal membrane oxygenation in pediatric respiratory failure"
      },
      "formula": "oxygenation_index",
      "formula_expression": "oxygenation_index = fio2 * mean_airway_pressure_cm_h2o * 100 / pao2_mm_hg",
      "fio2": 0.5,
      "pao2_mm_hg": 80.0,
      "mean_airway_pressure_cm_h2o": 12.0,
      "oxygenation_index": 7.5
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ortiz RM, Cilley RE, Bartlett RH",
        "doi": "10.1016/S0031-3955(16)36180-7",
        "id": "ortiz-bartlett-1987",
        "source": "Pediatr Clin North Am. 1987;34(1):39-46",
        "title": "Extracorporeal membrane oxygenation in pediatric respiratory failure"
      },
      "formula": "oxygenation_index",
      "formula_expression": "oxygenation_index = fio2 * mean_airway_pressure_cm_h2o * 100 / pao2_mm_hg",
      "fio2": 0.5,
      "pao2_mm_hg": 80.0,
      "mean_airway_pressure_cm_h2o": 12.0,
      "oxygenation_index": 7.5
    }
  ]
}

Response

Field Type Description
formula string oxygenation_index
formula_expression string Exact expression used
fio2 number Inspired oxygen fraction used
mean_airway_pressure_cm_h2o number Mean airway pressure in cm H2O used
pao2_mm_hg number Arterial PO2 used
oxygenation_index number FiO2 × mean airway pressure × 100 / PaO2, 1 decimal
citation object Ortiz, Cilley, and Bartlett 1987 citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Ortiz RM, Cilley RE, Bartlett RH",
    "doi": "10.1016/S0031-3955(16)36180-7",
    "id": "ortiz-bartlett-1987",
    "source": "Pediatr Clin North Am. 1987;34(1):39-46",
    "title": "Extracorporeal membrane oxygenation in pediatric respiratory failure"
  },
  "formula": "oxygenation_index",
  "formula_expression": "oxygenation_index = fio2 * mean_airway_pressure_cm_h2o * 100 / pao2_mm_hg",
  "fio2": 0.5,
  "pao2_mm_hg": 80.0,
  "mean_airway_pressure_cm_h2o": 12.0,
  "oxygenation_index": 7.5
}

Errors

HTTP Code When
400 invalid_fio2 fio2 must be a fraction from 0.21 to 1.0. Returned before settlement; you are not charged.
400 invalid_mean_airway_pressure mean_airway_pressure_cm_h2o must be a number from 4 to 45. Returned before settlement; you are not charged.
400 invalid_pao2 pao2_mm_hg must be a number from 20 to 700. Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.
402 payment_required Missing or invalid PAYMENT-SIGNATURE; decode the PAYMENT-REQUIRED header
409 payment_in_progress The same authorization nonce is already being settled; retry shortly
429 rate_limited Too many requests from this client
503 settlement_uncertain Settlement is unconfirmed; retry with the same PAYMENT-SIGNATURE
503 settle_failed Settlement failed; retry with the same PAYMENT-SIGNATURE shortly
503 facilitator_unavailable Payment facilitator unavailable
503 facilitator_misconfigured Payment facilitator is not configured
503 facilitator_unauthorized Payment facilitator rejected credentials
503 ledger_unavailable Payment ledger unavailable
503 payment_unavailable Payment processing unavailable

Related tools

  • A-a O2 gradient — Compute the alveolar–arterial oxygen gradient from arterial blood-gas values using the simplified ideal alveolar-gas equation.

Also searched as

  • OI
  • oxygenation index
  • oxygenation index OI
  • ventilator OI
  • FiO2 mean airway pressure PaO2
  • mean airway pressure oxygenation

Payment

Required query parameters must be present and valid. Invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments.

Guarantees

  • Invalid query parameters return HTTP 400 before settlement. You are not charged.
  • Settlement finishes before the tool executes (paymentFlow upfront). Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.