Neurology · LIVE

PRE score

Compute the Pittsburgh Response to Endovascular therapy (PRE) score from age, caller-assigned NIHSS, and ASPECTS using PRE = age + 2×NIHSS - 10×ASPECTS (Rangaraju 2015).

LIVE $0.005 USDC GET /api/calc/pre_score

Markdown: /docs/pre-score.md · Canonical: https://magentlab.com/docs/pre-score

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Pittsburgh Response to Endovascular therapy (PRE) score from age, caller-assigned NIHSS, and ASPECTS using PRE = age + 2×NIHSS - 10×ASPECTS (Rangaraju 2015).

When to use

When an agent needs the published Rangaraju 2015 PRE total, quartile, and recanalization-benefit stratum for large-vessel occlusion, and must not invent NIHSS or ASPECTS from a chart narrative or CT.

When not to use

• Not a medical device and not a thrombectomy recommendation.
• The caller assigns the NINDS NIHSS total and ASPECTS. magent does not assign NIHSS or read CT.
• Quartiles and recanalization-benefit groups are those published in Rangaraju 2015. magent does not invent outcome percents or extra cutpoints.
• This tool does not recommend for or against endovascular therapy.

Formula

PRE = age_years + 2 × nihss - 10 × aspects (Rangaraju 2015); integer arithmetic; no clamp on the total

Citation

Title

Pittsburgh Response to Endovascular therapy (PRE) score: optimizing patient selection for endovascular therapy for large vessel occlusion strokes

Authors

Rangaraju S, Aghaebrahim A, Streib C, Sun CH, Ribo M, Muchada M, Nogueira R, Frankel M, Gupta R, Jadhav A, Jovin TG

Source

J Neurointerv Surg. 2015;7(11):783-788

DOI

10.1136/neurintsurg-2014-011351

Worked example

Also searched as

• PRE score
• Pittsburgh Response to Endovascular therapy
• Rangaraju PRE
• PRE NIHSS ASPECTS
• large vessel occlusion PRE
• endovascular therapy PRE
• ASPECTS NIHSS age PRE
• Rangaraju 2015 PRE score

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/pre_score?age=65&nihss=18&aspects=8

Full URL: https://api.magentlab.com/api/calc/pre_score?age=65&nihss=18&aspects=8

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/pre_score?age=65&nihss=18&aspects=8"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/pre_score Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "65",
      "aspects": "8",
      "nihss": "18"
    },
    {
      "age": "65",
      "aspects": "8",
      "nihss": "18"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/pre_score",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Rangaraju S, Aghaebrahim A, Streib C, Sun CH, Ribo M, Muchada M, Nogueira R, Frankel M, Gupta R, Jadhav A, Jovin TG",
        "doi": "10.1136/neurintsurg-2014-011351",
        "id": "rangaraju-2015",
        "pmid": "25320216",
        "source": "J Neurointerv Surg. 2015;7(11):783-788",
        "title": "Pittsburgh Response to Endovascular therapy (PRE) score: optimizing patient selection for endovascular therapy for large vessel occlusion strokes"
      },
      "formula": "pre_score",
      "formula_expression": "PRE = age_years + 2 × nihss - 10 × aspects (Rangaraju 2015); integer arithmetic; no clamp on the total",
      "age_years": 65,
      "nihss": 18,
      "aspects": 8,
      "pre_quartile": "0-24",
      "pre_score": 21,
      "recanalization_stratum": "-24_to_49"
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Rangaraju S, Aghaebrahim A, Streib C, Sun CH, Ribo M, Muchada M, Nogueira R, Frankel M, Gupta R, Jadhav A, Jovin TG",
        "doi": "10.1136/neurintsurg-2014-011351",
        "id": "rangaraju-2015",
        "pmid": "25320216",
        "source": "J Neurointerv Surg. 2015;7(11):783-788",
        "title": "Pittsburgh Response to Endovascular therapy (PRE) score: optimizing patient selection for endovascular therapy for large vessel occlusion strokes"
      },
      "formula": "pre_score",
      "formula_expression": "PRE = age_years + 2 × nihss - 10 × aspects (Rangaraju 2015); integer arithmetic; no clamp on the total",
      "age_years": 65,
      "nihss": 18,
      "aspects": 8,
      "pre_quartile": "0-24",
      "pre_score": 21,
      "recanalization_stratum": "-24_to_49"
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Rangaraju S, Aghaebrahim A, Streib C, Sun CH, Ribo M, Muchada M, Nogueira R, Frankel M, Gupta R, Jadhav A, Jovin TG",
    "doi": "10.1136/neurintsurg-2014-011351",
    "id": "rangaraju-2015",
    "pmid": "25320216",
    "source": "J Neurointerv Surg. 2015;7(11):783-788",
    "title": "Pittsburgh Response to Endovascular therapy (PRE) score: optimizing patient selection for endovascular therapy for large vessel occlusion strokes"
  },
  "formula": "pre_score",
  "formula_expression": "PRE = age_years + 2 × nihss - 10 × aspects (Rangaraju 2015); integer arithmetic; no clamp on the total",
  "age_years": 65,
  "nihss": 18,
  "aspects": 8,
  "pre_quartile": "0-24",
  "pre_score": 21,
  "recanalization_stratum": "-24_to_49"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• NIHSS — Sum Brott 1989 NIH stroke scale points from 15 caller-assigned examination integers, including pupillary response and plantar reflex. Weaker-limb motor arm and leg. Does not apply later total-score severity bands.
• THRIVE — Compute the Flint 2010 THRIVE (Totaled Health Risks in Vascular Events) score from trichotomized age, trichotomized NIHSS, and the chronic disease scale (hypertension, diabetes mellitus, atrial fibrillation).
• mNIHSS — Sum Meyer/Lyden 2001 modified NIH stroke scale points from 11 caller-assigned NINDS-style examination integers, with left/right motor and sensory collapsed to 0-1. Does not apply total-score severity bands.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.