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Rome IV IBS criteria

Rome IV IBS

Apply the Mearin 2016 Rome IV IBS diagnostic criteria and return supporting_features_met (0-3) and whether the published IBS box holds (rome_iv_ibs).

LIVE $0.005 USDC GET /api/calc/rome_iv_ibs

Markdown: /docs/rome-iv-ibs.md · Canonical: https://magentlab.com/docs/rome-iv-ibs

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Mearin 2016 Rome IV IBS diagnostic criteria and return supporting_features_met (0-3) and whether the published IBS box holds (rome_iv_ibs).

When to use

When an agent already has the five caller-assigned Rome IV IBS flags as in Mearin 2016 and needs whether the published IBS box holds. magent does not examine the patient.

When not to use

  • Not a medical device.
  • Not a diagnosis. magent does not diagnose irritable bowel syndrome.
  • The caller assigns the five flags. magent does not examine the patient.
  • This tool is the Mearin 2016 Rome IV IBS diagnostic box only. Not Rome III (pain or discomfort at least 3 days per month), not Manning criteria, and not IBS-C/D/M/U subtype.

Formula

rome_iv_ibs iff pain_1_day_per_week_last_3_months and symptom_onset_at_least_6_months_prior and supporting_features_met >= 2; supporting_features_met counts related_to_defecation, associated_change_stool_frequency, and associated_change_stool_form (Mearin 2016 Rome IV IBS diagnostic criteria)

Citation

Title
Bowel Disorders
Authors
Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller RC
Source
Gastroenterology. 2016;150(6):1393-1407
DOI
10.1053/j.gastro.2016.02.031

Worked example

Pain, 6-month onset, and two supporting features

Given: associated_change_stool_form=falseassociated_change_stool_frequency=truepain_1_day_per_week_last_3_months=truerelated_to_defecation=truesymptom_onset_at_least_6_months_prior=true

  1. Recurrent abdominal pain at least 1 day per week in the last 3 months is true
  2. Symptom onset at least 6 months prior is true
  3. Related to defecation and change in stool frequency are true; change in stool form is false (2 of 3)
  4. rome_iv_ibs is true

Pain and 6-month onset with only one supporting feature

Given: associated_change_stool_form=falseassociated_change_stool_frequency=falsepain_1_day_per_week_last_3_months=truerelated_to_defecation=truesymptom_onset_at_least_6_months_prior=true

  1. Pain and 6-month onset hold
  2. Only related to defecation is true (1 of 3)
  3. rome_iv_ibs is false

Also searched as

  • Rome IV IBS
  • Rome IV irritable bowel
  • Mearin IBS criteria
  • functional bowel IBS 2016
  • IBS diagnostic criteria Rome IV
  • Mearin 2016 IBS
  • irritable bowel syndrome Rome IV
  • Rome IV IBS box

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/rome_iv_ibs?pain_1_day_per_week_last_3_months=true&symptom_onset_at_least_6_months_prior=true&related_to_defecation=true&associated_change_stool_frequency=true&associated_change_stool_form=false

Full URL: https://api.magentlab.com/api/calc/rome_iv_ibs?pain_1_day_per_week_last_3_months=true&symptom_onset_at_least_6_months_prior=true&related_to_defecation=true&associated_change_stool_frequency=true&associated_change_stool_form=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/rome_iv_ibs?pain_1_day_per_week_last_3_months=true&symptom_onset_at_least_6_months_prior=true&related_to_defecation=true&associated_change_stool_frequency=true&associated_change_stool_form=false"

Parameters

Name Type Required Description
pain_1_day_per_week_last_3_months boolean required Recurrent abdominal pain on average at least 1 day per week in the last 3 months (Mearin 2016). Pain only, not discomfort. true or false as assigned by the caller. magent does not examine the patient.
symptom_onset_at_least_6_months_prior boolean required Criteria fulfilled for the last 3 months with symptom onset at least 6 months before diagnosis, as assigned (Mearin 2016). true or false as assigned by the caller. magent does not take a history.
related_to_defecation boolean required Pain related to defecation (one of three supporting features; at least two required). true or false as assigned by the caller.
associated_change_stool_frequency boolean required Pain associated with a change in frequency of stool (one of three supporting features; at least two required). true or false as assigned by the caller.
associated_change_stool_form boolean required Pain associated with a change in form (appearance) of stool (one of three supporting features; at least two required). true or false as assigned by the caller.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/rome_iv_ibs Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "associated_change_stool_form": "false",
      "associated_change_stool_frequency": "true",
      "pain_1_day_per_week_last_3_months": "true",
      "related_to_defecation": "true",
      "symptom_onset_at_least_6_months_prior": "true"
    },
    {
      "associated_change_stool_form": "false",
      "associated_change_stool_frequency": "true",
      "pain_1_day_per_week_last_3_months": "true",
      "related_to_defecation": "true",
      "symptom_onset_at_least_6_months_prior": "true"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/rome_iv_ibs",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller RC",
        "doi": "10.1053/j.gastro.2016.02.031",
        "id": "mearin-2016",
        "pmid": "27144627",
        "source": "Gastroenterology. 2016;150(6):1393-1407",
        "title": "Bowel Disorders"
      },
      "formula": "rome_iv_ibs",
      "formula_expression": "rome_iv_ibs iff pain_1_day_per_week_last_3_months and symptom_onset_at_least_6_months_prior and supporting_features_met >= 2; supporting_features_met counts related_to_defecation, associated_change_stool_frequency, and associated_change_stool_form (Mearin 2016 Rome IV IBS diagnostic criteria)",
      "criteria": [
        {
          "factor": "pain_1_day_per_week_last_3_months",
          "met": true
        },
        {
          "factor": "symptom_onset_at_least_6_months_prior",
          "met": true
        },
        {
          "factor": "related_to_defecation",
          "met": true
        },
        {
          "factor": "associated_change_stool_frequency",
          "met": true
        },
        {
          "factor": "associated_change_stool_form",
          "met": false
        },
        {
          "value": 2,
          "factor": "supporting_features_ge_2",
          "met": true
        }
      ],
      "supporting_features_met": 2,
      "rome_iv_ibs": true
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller RC",
        "doi": "10.1053/j.gastro.2016.02.031",
        "id": "mearin-2016",
        "pmid": "27144627",
        "source": "Gastroenterology. 2016;150(6):1393-1407",
        "title": "Bowel Disorders"
      },
      "formula": "rome_iv_ibs",
      "formula_expression": "rome_iv_ibs iff pain_1_day_per_week_last_3_months and symptom_onset_at_least_6_months_prior and supporting_features_met >= 2; supporting_features_met counts related_to_defecation, associated_change_stool_frequency, and associated_change_stool_form (Mearin 2016 Rome IV IBS diagnostic criteria)",
      "criteria": [
        {
          "factor": "pain_1_day_per_week_last_3_months",
          "met": true
        },
        {
          "factor": "symptom_onset_at_least_6_months_prior",
          "met": true
        },
        {
          "factor": "related_to_defecation",
          "met": true
        },
        {
          "factor": "associated_change_stool_frequency",
          "met": true
        },
        {
          "factor": "associated_change_stool_form",
          "met": false
        },
        {
          "value": 2,
          "factor": "supporting_features_ge_2",
          "met": true
        }
      ],
      "supporting_features_met": 2,
      "rome_iv_ibs": true
    }
  ]
}

Response

Field Type Description
formula string rome_iv_ibs
formula_expression string Mearin 2016 Rome IV IBS box: pain at least 1 day/week for 3 months, onset 6 months, and at least 2 of 3 supporting features
supporting_features_met integer Count of true supporting features among related to defecation, change in stool frequency, and change in stool form (0-3)
rome_iv_ibs boolean true only when pain, 6-month onset, and at least two supporting features all hold. Not a diagnosis.
criteria array Per-factor rows with factor and met; supporting_features_ge_2 includes value 0-3
citation object Mearin 2016 Gastroenterology citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller RC",
    "doi": "10.1053/j.gastro.2016.02.031",
    "id": "mearin-2016",
    "pmid": "27144627",
    "source": "Gastroenterology. 2016;150(6):1393-1407",
    "title": "Bowel Disorders"
  },
  "formula": "rome_iv_ibs",
  "formula_expression": "rome_iv_ibs iff pain_1_day_per_week_last_3_months and symptom_onset_at_least_6_months_prior and supporting_features_met >= 2; supporting_features_met counts related_to_defecation, associated_change_stool_frequency, and associated_change_stool_form (Mearin 2016 Rome IV IBS diagnostic criteria)",
  "criteria": [
    {
      "factor": "pain_1_day_per_week_last_3_months",
      "met": true
    },
    {
      "factor": "symptom_onset_at_least_6_months_prior",
      "met": true
    },
    {
      "factor": "related_to_defecation",
      "met": true
    },
    {
      "factor": "associated_change_stool_frequency",
      "met": true
    },
    {
      "factor": "associated_change_stool_form",
      "met": false
    },
    {
      "value": 2,
      "factor": "supporting_features_ge_2",
      "met": true
    }
  ],
  "supporting_features_met": 2,
  "rome_iv_ibs": true
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_flag boolean clinical flags must be true or false Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • Rome III IBS — Apply the Longstreth 2006 Rome III IBS diagnostic criteria and return supporting_features_met (0-3) and whether the published IBS box holds (rome_iii_ibs).
  • HBI — Sum Harvey 1980 simple-index items (previous-day well-being, abdominal pain, liquid stools, abdominal mass, and one point per listed complication) and return the total. Does not return later remission or activity bands.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.