ROPE score

ROPE

Compute the Kent 2013 Risk of Paradoxical Embolism (ROPE) index from Table 4 age decades and five caller-assigned vascular and infarct flags.

LIVE $0.005 USDC GET /api/calc/rope

Markdown: /docs/rope.md · Canonical: https://magentlab.com/docs/rope

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Kent 2013 Risk of Paradoxical Embolism (ROPE) index from Table 4 age decades and five caller-assigned vascular and infarct flags.

When to use

When an agent needs the published Kent 2013 Table 4 ROPE total and must not invent a PFO diagnosis, a closure indication, or a PASCAL classification.

When not to use

Not a medical device. Not a PFO or cryptogenic-stroke diagnosis.
Not a closure or device-indication order. This is Kent 2013 ROPE, not PASCAL.
The five vascular and infarct flags are caller-assigned. magent does not read imaging or a smoking history.

Formula

ROPE = age_points + no_hypertension 1 + no_diabetes 1 + no_prior_stroke_tia 1 + nonsmoker 1 + cortical_infarct 1; age 18-29 5, 30-39 4, 40-49 3, 50-59 2, 60-69 1, >=70 0; Kent 2013 Table 4; max 10

Citation

Title: An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke
Authors: Kent DM, Ruthazer R, Weimar C, Mas JL, Serena J, Homma S, Di Angelantonio E, Di Tullio MR, Lutz JS, Elkind MSV, Griffith J, Jaigobin C, Mattle HP, Michel P, Mono ML, Nedeltchev K, Papetti F, Thaler DE
Source: Neurology. 2013;81(7):619-625
DOI: 10.1212/WNL.0b013e3182a08d59

Worked example

Age 70, all five flags false

Given: age=70cortical_infarct=falseno_diabetes=falseno_hypertension=falseno_prior_stroke_tia=falsenonsmoker=false

Age 70 (>=70) → 0; no_hypertension, no_diabetes, no_prior_stroke_tia, nonsmoker, and cortical_infarct all false → 0
Score = 0 (max 10); rope_stratum 0_to_3

Also searched as

ROPE score
Risk of Paradoxical Embolism
Kent ROPE
patent foramen ovale index
cryptogenic stroke PFO
stroke-related vs incidental PFO
Kent 2013 ROPE
ROPE PFO

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/rope?age=70&no_hypertension=false&no_diabetes=false&no_prior_stroke_tia=false&nonsmoker=false&cortical_infarct=false

Full URL: https://api.magentlab.com/api/calc/rope?age=70&no_hypertension=false&no_diabetes=false&no_prior_stroke_tia=false&nonsmoker=false&cortical_infarct=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/rope?age=70&no_hypertension=false&no_diabetes=false&no_prior_stroke_tia=false&nonsmoker=false&cortical_infarct=false"

Parameters

Name	Type	Required	Description
`age`	integer	required	Age in years (18-120). Kent 2013 Table 4: 18-29 scores 5; 30-39 scores 4; 40-49 scores 3; 50-59 scores 2; 60-69 scores 1; 70 or older scores 0.
`no_hypertension`	boolean	required	Absence of hypertension (Kent 2013). Caller-assigned. true scores 1; false scores 0.
`no_diabetes`	boolean	required	Absence of diabetes (Kent 2013). Caller-assigned. true scores 1; false scores 0.
`no_prior_stroke_tia`	boolean	required	Absence of prior stroke or TIA (Kent 2013). Caller-assigned. true scores 1; false scores 0.
`nonsmoker`	boolean	required	Nonsmoker (Kent 2013). Caller-assigned. magent does not read a smoking history. true scores 1; false scores 0.
`cortical_infarct`	boolean	required	Cortical infarct on imaging (Kent 2013). Caller-assigned. magent does not read imaging. true scores 1; false scores 0.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/rope Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "70",
      "cortical_infarct": "false",
      "no_diabetes": "false",
      "no_hypertension": "false",
      "no_prior_stroke_tia": "false",
      "nonsmoker": "false"
    },
    {
      "age": "70",
      "cortical_infarct": "false",
      "no_diabetes": "false",
      "no_hypertension": "false",
      "no_prior_stroke_tia": "false",
      "nonsmoker": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/rope",
  "items": [
    {
      "components": [
        {
          "value": 70,
          "factor": "age",
          "points": 0,
          "present": false
        },
        {
          "factor": "no_hypertension",
          "points": 0,
          "present": false
        },
        {
          "factor": "no_diabetes",
          "points": 0,
          "present": false
        },
        {
          "factor": "no_prior_stroke_tia",
          "points": 0,
          "present": false
        },
        {
          "factor": "nonsmoker",
          "points": 0,
          "present": false
        },
        {
          "factor": "cortical_infarct",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Kent DM, Ruthazer R, Weimar C, Mas JL, Serena J, Homma S, Di Angelantonio E, Di Tullio MR, Lutz JS, Elkind MSV, Griffith J, Jaigobin C, Mattle HP, Michel P, Mono ML, Nedeltchev K, Papetti F, Thaler DE",
        "doi": "10.1212/WNL.0b013e3182a08d59",
        "id": "kent-2013",
        "pmid": "23864310",
        "source": "Neurology. 2013;81(7):619-625",
        "title": "An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke"
      },
      "formula": "rope",
      "formula_expression": "ROPE = age_points + no_hypertension 1 + no_diabetes 1 + no_prior_stroke_tia 1 + nonsmoker 1 + cortical_infarct 1; age 18-29 5, 30-39 4, 40-49 3, 50-59 2, 60-69 1, >=70 0; Kent 2013 Table 4; max 10",
      "age_years": 70,
      "max_score": 10,
      "score": 0,
      "rope_stratum": "0_to_3"
    },
    {
      "components": [
        {
          "value": 70,
          "factor": "age",
          "points": 0,
          "present": false
        },
        {
          "factor": "no_hypertension",
          "points": 0,
          "present": false
        },
        {
          "factor": "no_diabetes",
          "points": 0,
          "present": false
        },
        {
          "factor": "no_prior_stroke_tia",
          "points": 0,
          "present": false
        },
        {
          "factor": "nonsmoker",
          "points": 0,
          "present": false
        },
        {
          "factor": "cortical_infarct",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Kent DM, Ruthazer R, Weimar C, Mas JL, Serena J, Homma S, Di Angelantonio E, Di Tullio MR, Lutz JS, Elkind MSV, Griffith J, Jaigobin C, Mattle HP, Michel P, Mono ML, Nedeltchev K, Papetti F, Thaler DE",
        "doi": "10.1212/WNL.0b013e3182a08d59",
        "id": "kent-2013",
        "pmid": "23864310",
        "source": "Neurology. 2013;81(7):619-625",
        "title": "An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke"
      },
      "formula": "rope",
      "formula_expression": "ROPE = age_points + no_hypertension 1 + no_diabetes 1 + no_prior_stroke_tia 1 + nonsmoker 1 + cortical_infarct 1; age 18-29 5, 30-39 4, 40-49 3, 50-59 2, 60-69 1, >=70 0; Kent 2013 Table 4; max 10",
      "age_years": 70,
      "max_score": 10,
      "score": 0,
      "rope_stratum": "0_to_3"
    }
  ]
}

Response

Field	Type	Description
`formula`	string	rope
`formula_expression`	string	Exact expression used
`score`	integer	Total points 0-10
`max_score`	integer	Always 10
`rope_stratum`	string	Kent 2013 abstract groupings: 0_to_3 (score 0-3), 9_to_10 (score 9-10), or 4_to_8 residual (score 4-8). Not a named risk class.
`age_years`	integer	Age used for Table 4 decade points
`components`	array	Per-factor points
`citation`	object	Kent 2013 Neurology citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "components": [
    {
      "value": 70,
      "factor": "age",
      "points": 0,
      "present": false
    },
    {
      "factor": "no_hypertension",
      "points": 0,
      "present": false
    },
    {
      "factor": "no_diabetes",
      "points": 0,
      "present": false
    },
    {
      "factor": "no_prior_stroke_tia",
      "points": 0,
      "present": false
    },
    {
      "factor": "nonsmoker",
      "points": 0,
      "present": false
    },
    {
      "factor": "cortical_infarct",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Kent DM, Ruthazer R, Weimar C, Mas JL, Serena J, Homma S, Di Angelantonio E, Di Tullio MR, Lutz JS, Elkind MSV, Griffith J, Jaigobin C, Mattle HP, Michel P, Mono ML, Nedeltchev K, Papetti F, Thaler DE",
    "doi": "10.1212/WNL.0b013e3182a08d59",
    "id": "kent-2013",
    "pmid": "23864310",
    "source": "Neurology. 2013;81(7):619-625",
    "title": "An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke"
  },
  "formula": "rope",
  "formula_expression": "ROPE = age_points + no_hypertension 1 + no_diabetes 1 + no_prior_stroke_tia 1 + nonsmoker 1 + cortical_infarct 1; age 18-29 5, 30-39 4, 40-49 3, 50-59 2, 60-69 1, >=70 0; Kent 2013 Table 4; max 10",
  "age_years": 70,
  "max_score": 10,
  "score": 0,
  "rope_stratum": "0_to_3"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_age`	age must be an integer from 18 to 120 Returned before settlement; you are not charged.
400	`invalid_flag`	boolean clinical flags must be true or false Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

ABCD2 score — Compute the ABCD2 score as age, blood pressure, caller-assigned clinical features, symptom duration, and diabetes.
THRIVE — Compute the Flint 2010 THRIVE (Totaled Health Risks in Vascular Events) score from trichotomized age, trichotomized NIHSS, and the chronic disease scale (hypertension, diabetes mellitus, atrial fibrillation).

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.