MAGENT

Kidney · WEDGE

Urine protein/creatinine ratio (Ginsberg 1983)

Urine PCR

Compute the Ginsberg 1983 urine protein/creatinine ratio (mg/mg) from a single-void urine protein and urine creatinine, and return that rounded ratio as estimated_g_day (numeric estimate of 24-h protein g/day).

WEDGE $0.005 USDC GET /api/calc/urine_pcr

Markdown: /docs/urine-pcr.md · Canonical: https://magentlab.com/docs/urine-pcr

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Ginsberg 1983 urine protein/creatinine ratio (mg/mg) from a single-void urine protein and urine creatinine, and return that rounded ratio as estimated_g_day (numeric estimate of 24-h protein g/day).

When to use

When an agent has a single-void urine protein and urine creatinine and must not invent a 24-h collection or an albumin/creatinine (ACR) result.

When not to use

  • Not a medical device. Ginsberg 1983 bands are published protein/creatinine cut-points (ratio <0.2 within normal limits; ratio >3.5 nephrotic-range), not a diagnosis of nephrotic syndrome.
  • magent does not collect urine. This is not a 24-hour urine collection. estimated_g_day equals the rounded ratio as a numeric estimate of 24-h protein g/day from Ginsberg 1983, not a measured collection.
  • Not ACR (albumin/creatinine). This calculator uses total urine protein, not albumin.
  • Exact ratios 0.2 and 3.5 are the mid band (the paper says less than 0.2 and more than 3.5).

Formula

protein_creatinine_ratio = urine_protein_mg_dl / urine_creatinine_mg_dl

Citation

Title
Use of single voided urine samples to estimate quantitative proteinuria.
Authors
Ginsberg JM, Chang BS, Matarese RA, Garella S
Source
N Engl J Med. 1983;309(25):1543-1546
DOI
10.1056/nejm198312223092503

Worked example

Protein 100 mg/dL, creatinine 100 mg/dL

Given: urine_creatinine_mg_dl=100urine_protein_mg_dl=100

  1. protein_creatinine_ratio = 100 / 100 = 1.0 (mg/mg, rounded to 2 decimals)
  2. estimated_g_day = 1.0 (Ginsberg 1983 numeric estimate of 24-h protein g/day)
  3. Ginsberg band: not <0.2 and not >3.5 → 0_2_to_3_5

Also searched as

  • urine protein creatinine ratio
  • protein/creatinine ratio
  • urine PCR
  • UPCR
  • spot urine protein
  • Ginsberg proteinuria
  • spot proteinuria ratio
  • urine protein/creatinine

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/urine_pcr?urine_protein_mg_dl=100&urine_creatinine_mg_dl=100

Full URL: https://api.magentlab.com/api/calc/urine_pcr?urine_protein_mg_dl=100&urine_creatinine_mg_dl=100

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/urine_pcr?urine_protein_mg_dl=100&urine_creatinine_mg_dl=100"

Parameters

Name Type Required Description
urine_protein_mg_dl number required Urine total protein in mg/dL (0.1-2000). Total protein, not albumin.
urine_creatinine_mg_dl number optional Urine creatinine in mg/dL (1-500). Provide this or urine_creatinine_umol_l.
urine_creatinine_umol_l number optional Urine creatinine in µmol/L (88-44210). Converted as mg/dL = µmol/L / 88.42.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/urine_pcr Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "urine_creatinine_mg_dl": "100",
      "urine_protein_mg_dl": "100"
    },
    {
      "urine_creatinine_mg_dl": "100",
      "urine_protein_mg_dl": "100"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/urine_pcr",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ginsberg JM, Chang BS, Matarese RA, Garella S",
        "doi": "10.1056/nejm198312223092503",
        "id": "ginsberg-1983",
        "pmid": "6656849",
        "source": "N Engl J Med. 1983;309(25):1543-1546",
        "title": "Use of single voided urine samples to estimate quantitative proteinuria."
      },
      "formula": "ginsberg",
      "formula_expression": "protein_creatinine_ratio = urine_protein_mg_dl / urine_creatinine_mg_dl",
      "urine_creatinine_mg_dl": 100.0,
      "estimated_g_day": 1.0,
      "ginsberg_band": "0_2_to_3_5",
      "protein_creatinine_ratio": 1.0,
      "urine_protein_mg_dl": 100.0
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ginsberg JM, Chang BS, Matarese RA, Garella S",
        "doi": "10.1056/nejm198312223092503",
        "id": "ginsberg-1983",
        "pmid": "6656849",
        "source": "N Engl J Med. 1983;309(25):1543-1546",
        "title": "Use of single voided urine samples to estimate quantitative proteinuria."
      },
      "formula": "ginsberg",
      "formula_expression": "protein_creatinine_ratio = urine_protein_mg_dl / urine_creatinine_mg_dl",
      "urine_creatinine_mg_dl": 100.0,
      "estimated_g_day": 1.0,
      "ginsberg_band": "0_2_to_3_5",
      "protein_creatinine_ratio": 1.0,
      "urine_protein_mg_dl": 100.0
    }
  ]
}

Response

Field Type Description
formula string ginsberg
formula_expression string Exact expression used
urine_protein_mg_dl number Urine total protein in mg/dL
urine_creatinine_mg_dl number Normalized urine creatinine in mg/dL
protein_creatinine_ratio number Protein/creatinine ratio in mg/mg, 2 decimal places
estimated_g_day number Numeric estimate of 24-h protein g/day, equal to the rounded ratio (Ginsberg 1983). Not a measured 24-h collection.
ginsberg_band string Ginsberg 1983 bands: lt_0_2 (ratio <0.2, within normal limits), gt_3_5 (ratio >3.5, nephrotic-range), or 0_2_to_3_5. Exact 0.2 and 3.5 are mid. Not a diagnosis.
citation object NEJM 1983 citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Ginsberg JM, Chang BS, Matarese RA, Garella S",
    "doi": "10.1056/nejm198312223092503",
    "id": "ginsberg-1983",
    "pmid": "6656849",
    "source": "N Engl J Med. 1983;309(25):1543-1546",
    "title": "Use of single voided urine samples to estimate quantitative proteinuria."
  },
  "formula": "ginsberg",
  "formula_expression": "protein_creatinine_ratio = urine_protein_mg_dl / urine_creatinine_mg_dl",
  "urine_creatinine_mg_dl": 100.0,
  "estimated_g_day": 1.0,
  "ginsberg_band": "0_2_to_3_5",
  "protein_creatinine_ratio": 1.0,
  "urine_protein_mg_dl": 100.0
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_urine_pcr urine_protein_mg_dl must be a number from 0.1 to 2000 (Ginsberg 1983 protein/creatinine ratio). Returned before settlement; you are not charged.
400 invalid_urine_creatinine urine_creatinine_mg_dl (1-500) or urine_creatinine_umol_l (88-44210) is required. Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • FENa — Compute fractional excretion of sodium from plasma and urine sodium and creatinine using Espinel 1976.
  • FEUrea — Compute fractional excretion of urea (FEUN) from BUN, urine urea nitrogen, plasma creatinine, and urine creatinine.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.