Bacterial Meningitis Score (Nigrovic)

Bacterial Meningitis Score

Sum the Nigrovic 2002 Bacterial Meningitis Score weights for children with CSF pleocytosis and return very_low_risk (0) or not_low_risk (≥1).

LIVE $0.005 USDC GET /api/calc/bacterial_meningitis

Markdown: /docs/bacterial-meningitis.md · Canonical: https://magentlab.com/docs/bacterial-meningitis

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Sum the Nigrovic 2002 Bacterial Meningitis Score weights for children with CSF pleocytosis and return very_low_risk (0) or not_low_risk (≥1).

When to use

When an agent needs the published Bacterial Meningitis Score point total and band and must not invent a later numeric cutoff, a meningitis diagnosis, or an antibiotic or LP order.

When not to use

Not a medical device and not a meningitis diagnosis or an antibiotic/LP order. magent does not examine the patient.
Applies to children with CSF pleocytosis as in Nigrovic 2002. It is not a neonatal meningitis score.
magent does not stain CSF, count neutrophils, assay protein, or witness a seizure. All five inputs are caller-assigned flags.
CSF Gram stain true scores 2 points in Nigrovic 2002. It does not score 1.
very_low_risk is score 0 (lack all criteria). not_low_risk is score ≥1. Do not apply a later numeric cutoff.

Formula

Bacterial Meningitis Score = csf_gram_stain 2 + csf_anc_ge_1000 1 + csf_protein_ge_80 1 + peripheral_anc_ge_10000 1 + seizure 1; Nigrovic 2002; max 6; very_low_risk 0, not_low_risk ≥1

Citation

Title: Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era
Authors: Nigrovic LE, Kuppermann N, Malley R
Source: Pediatrics. 2002;110(4):712-719
DOI: 10.1542/peds.110.4.712

Worked example

All flags false

Given: csf_anc_ge_1000=falsecsf_gram_stain=falsecsf_protein_ge_80=falseperipheral_anc_ge_10000=falseseizure=false

All five caller-assigned flags false → 0
Score = 0 (max 6); bacterial_meningitis_band = very_low_risk

CSF Gram stain true

Given: csf_anc_ge_1000=falsecsf_gram_stain=truecsf_protein_ge_80=falseperipheral_anc_ge_10000=falseseizure=false

csf_gram_stain → 2; remaining flags 0
Score = 2 (max 6); bacterial_meningitis_band = not_low_risk (≥1)

Also searched as

Bacterial Meningitis Score
Nigrovic 2002
Nigrovic BMS
pediatric bacterial meningitis score
CSF Gram stain meningitis
very low risk bacterial meningitis

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/bacterial_meningitis?csf_gram_stain=false&csf_anc_ge_1000=false&csf_protein_ge_80=false&peripheral_anc_ge_10000=false&seizure=false

Full URL: https://api.magentlab.com/api/calc/bacterial_meningitis?csf_gram_stain=false&csf_anc_ge_1000=false&csf_protein_ge_80=false&peripheral_anc_ge_10000=false&seizure=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/bacterial_meningitis?csf_gram_stain=false&csf_anc_ge_1000=false&csf_protein_ge_80=false&peripheral_anc_ge_10000=false&seizure=false"

Parameters

Name	Type	Required	Description
`csf_gram_stain`	boolean	required	Positive CSF Gram stain as assigned by the caller (Nigrovic 2002). true scores 2, not 1. magent does not stain CSF.
`csf_anc_ge_1000`	boolean	required	CSF ANC ≥1000 cells/µL as assigned by the caller (Nigrovic 2002). true scores 1. magent does not count neutrophils.
`csf_protein_ge_80`	boolean	required	CSF protein ≥80 mg/dL as assigned by the caller (Nigrovic 2002). true scores 1. magent does not assay protein.
`peripheral_anc_ge_10000`	boolean	required	Peripheral ANC ≥10 000 cells/µL as assigned by the caller (Nigrovic 2002). true scores 1. magent does not count neutrophils.
`seizure`	boolean	required	Seizure at or before presentation as assigned by the caller (Nigrovic 2002). true scores 1. magent does not witness a seizure.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/bacterial_meningitis Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "csf_anc_ge_1000": "false",
      "csf_gram_stain": "false",
      "csf_protein_ge_80": "false",
      "peripheral_anc_ge_10000": "false",
      "seizure": "false"
    },
    {
      "csf_anc_ge_1000": "false",
      "csf_gram_stain": "false",
      "csf_protein_ge_80": "false",
      "peripheral_anc_ge_10000": "false",
      "seizure": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/bacterial_meningitis",
  "items": [
    {
      "components": [
        {
          "factor": "csf_gram_stain",
          "points": 0,
          "present": false
        },
        {
          "factor": "csf_anc_ge_1000",
          "points": 0,
          "present": false
        },
        {
          "factor": "csf_protein_ge_80",
          "points": 0,
          "present": false
        },
        {
          "factor": "peripheral_anc_ge_10000",
          "points": 0,
          "present": false
        },
        {
          "factor": "seizure",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Nigrovic LE, Kuppermann N, Malley R",
        "doi": "10.1542/peds.110.4.712",
        "id": "nigrovic-2002",
        "pmid": "12359784",
        "source": "Pediatrics. 2002;110(4):712-719",
        "title": "Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era"
      },
      "formula": "bacterial_meningitis",
      "formula_expression": "Bacterial Meningitis Score = csf_gram_stain 2 + csf_anc_ge_1000 1 + csf_protein_ge_80 1 + peripheral_anc_ge_10000 1 + seizure 1; Nigrovic 2002; max 6; very_low_risk 0, not_low_risk ≥1",
      "max_score": 6,
      "score": 0,
      "bacterial_meningitis_band": "very_low_risk"
    },
    {
      "components": [
        {
          "factor": "csf_gram_stain",
          "points": 0,
          "present": false
        },
        {
          "factor": "csf_anc_ge_1000",
          "points": 0,
          "present": false
        },
        {
          "factor": "csf_protein_ge_80",
          "points": 0,
          "present": false
        },
        {
          "factor": "peripheral_anc_ge_10000",
          "points": 0,
          "present": false
        },
        {
          "factor": "seizure",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Nigrovic LE, Kuppermann N, Malley R",
        "doi": "10.1542/peds.110.4.712",
        "id": "nigrovic-2002",
        "pmid": "12359784",
        "source": "Pediatrics. 2002;110(4):712-719",
        "title": "Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era"
      },
      "formula": "bacterial_meningitis",
      "formula_expression": "Bacterial Meningitis Score = csf_gram_stain 2 + csf_anc_ge_1000 1 + csf_protein_ge_80 1 + peripheral_anc_ge_10000 1 + seizure 1; Nigrovic 2002; max 6; very_low_risk 0, not_low_risk ≥1",
      "max_score": 6,
      "score": 0,
      "bacterial_meningitis_band": "very_low_risk"
    }
  ]
}

Response

Field	Type	Description
`formula`	string	bacterial_meningitis
`formula_expression`	string	Exact expression used
`score`	integer	Bacterial Meningitis Score points 0-6
`max_score`	integer	Always 6
`bacterial_meningitis_band`	string	very_low_risk when score is 0, not_low_risk when score ≥1 (Nigrovic 2002 lack-all-criteria rule). Not a meningitis diagnosis or an antibiotic/LP order.
`components`	array	Per-factor points
`citation`	object	Nigrovic 2002 Pediatrics citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "components": [
    {
      "factor": "csf_gram_stain",
      "points": 0,
      "present": false
    },
    {
      "factor": "csf_anc_ge_1000",
      "points": 0,
      "present": false
    },
    {
      "factor": "csf_protein_ge_80",
      "points": 0,
      "present": false
    },
    {
      "factor": "peripheral_anc_ge_10000",
      "points": 0,
      "present": false
    },
    {
      "factor": "seizure",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Nigrovic LE, Kuppermann N, Malley R",
    "doi": "10.1542/peds.110.4.712",
    "id": "nigrovic-2002",
    "pmid": "12359784",
    "source": "Pediatrics. 2002;110(4):712-719",
    "title": "Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era"
  },
  "formula": "bacterial_meningitis",
  "formula_expression": "Bacterial Meningitis Score = csf_gram_stain 2 + csf_anc_ge_1000 1 + csf_protein_ge_80 1 + peripheral_anc_ge_10000 1 + seizure 1; Nigrovic 2002; max 6; very_low_risk 0, not_low_risk ≥1",
  "max_score": 6,
  "score": 0,
  "bacterial_meningitis_band": "very_low_risk"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_flag`	boolean clinical flags must be true or false Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

Glasgow Coma Scale — Compute the Glasgow Coma Scale as the sum of caller-assigned eye, verbal, and motor integers. The 1974 or 1976 edition is required.
SIRS — Compute the Bone 1992 ACCP/SCCM SIRS criteria from temperature, heart rate, respiratory rate, and WBC, with optional PaCO2 and band percent.
PECARN pediatric head CT — Apply the Kuppermann 2009 PECARN prediction trees and return high, intermediate, or low risk of clinically important brain injury from caller-assigned findings after pediatric head trauma.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.