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SIRS

Compute the Bone 1992 ACCP/SCCM SIRS criteria from temperature, heart rate, respiratory rate, and WBC, with optional PaCO2 and band percent.

LIVE $0.005 USDC GET /api/calc/sirs

Markdown: /docs/sirs.md · Canonical: https://magentlab.com/docs/sirs

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Bone 1992 ACCP/SCCM SIRS criteria from temperature, heart rate, respiratory rate, and WBC, with optional PaCO2 and band percent.

When to use

When an agent needs the published 1992 SIRS definition and must not substitute Sepsis-3, qSOFA, or SOFA, or treat the result as a diagnosis of sepsis.

When not to use

• Not a diagnosis of sepsis, severe sepsis, or septic shock. magent does not require a suspected-infection flag.
• This is Bone 1992 ACCP/SCCM SIRS only. It is not Sepsis-3, not qSOFA, and not SOFA.
• Thresholds are strict inequalities as published: temperature >38 or <36 °C, heart rate >90, respiratory rate >20 or PaCO2 <32 mm Hg, WBC >12000 or <4000/µL or bands >10%.
• PaCO2 and band percent are optional. Omitted PaCO2 uses respiratory rate only; omitted bands uses WBC only.

Formula

SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4

Citation

Title

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis

Authors

Bone RC, Balk RA, Cerra FB, et al.

Source

Chest. 1992;101(6):1644-1655

DOI

10.1378/chest.101.6.1644

Worked example

Also searched as

• SIRS criteria
• systemic inflammatory response syndrome
• Bone 1992 SIRS
• ACCP SCCM SIRS
• SIRS score
• SIRS definition

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/sirs?temperature_c=37.0&heart_rate_bpm=80&respiratory_rate=16&wbc_ul=8000

Full URL: https://api.magentlab.com/api/calc/sirs?temperature_c=37.0&heart_rate_bpm=80&respiratory_rate=16&wbc_ul=8000

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/sirs?temperature_c=37.0&heart_rate_bpm=80&respiratory_rate=16&wbc_ul=8000"

Parameters

Bulk (POST)

POST the same path with a JSON items array. Price is n times the GET unit. Invalid items return HTTP 400 before settlement.

POST /api/calc/sirs Max 25 unit_amount * n PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "heart_rate_bpm": "80",
      "respiratory_rate": "16",
      "temperature_c": "37.0",
      "wbc_ul": "8000"
    },
    {
      "heart_rate_bpm": "80",
      "respiratory_rate": "16",
      "temperature_c": "37.0",
      "wbc_ul": "8000"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/sirs",
  "items": [
    {
      "components": [
        {
          "value": 37.0,
          "factor": "temperature",
          "points": 0,
          "present": false
        },
        {
          "value": 80,
          "factor": "heart_rate_gt_90",
          "points": 0,
          "present": false
        },
        {
          "value": 16,
          "factor": "respiratory",
          "points": 0,
          "present": false
        },
        {
          "value": 8.0e3,
          "factor": "wbc",
          "points": 0,
          "present": false
        }
      ],
      "wbc_per_ul": 8.0e3,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Bone RC, Balk RA, Cerra FB, et al.",
        "doi": "10.1378/chest.101.6.1644",
        "id": "bone-1992",
        "source": "Chest. 1992;101(6):1644-1655",
        "title": "Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis"
      },
      "formula": "sirs",
      "formula_expression": "SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4",
      "max_score": 4,
      "temperature_c": 37.0,
      "heart_rate_bpm": 80,
      "respiratory_rate": 16,
      "sirs_criteria_met": 0,
      "sirs_present": false
    },
    {
      "components": [
        {
          "value": 37.0,
          "factor": "temperature",
          "points": 0,
          "present": false
        },
        {
          "value": 80,
          "factor": "heart_rate_gt_90",
          "points": 0,
          "present": false
        },
        {
          "value": 16,
          "factor": "respiratory",
          "points": 0,
          "present": false
        },
        {
          "value": 8.0e3,
          "factor": "wbc",
          "points": 0,
          "present": false
        }
      ],
      "wbc_per_ul": 8.0e3,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Bone RC, Balk RA, Cerra FB, et al.",
        "doi": "10.1378/chest.101.6.1644",
        "id": "bone-1992",
        "source": "Chest. 1992;101(6):1644-1655",
        "title": "Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis"
      },
      "formula": "sirs",
      "formula_expression": "SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4",
      "max_score": 4,
      "temperature_c": 37.0,
      "heart_rate_bpm": 80,
      "respiratory_rate": 16,
      "sirs_criteria_met": 0,
      "sirs_present": false
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "components": [
    {
      "value": 37.0,
      "factor": "temperature",
      "points": 0,
      "present": false
    },
    {
      "value": 80,
      "factor": "heart_rate_gt_90",
      "points": 0,
      "present": false
    },
    {
      "value": 16,
      "factor": "respiratory",
      "points": 0,
      "present": false
    },
    {
      "value": 8.0e3,
      "factor": "wbc",
      "points": 0,
      "present": false
    }
  ],
  "wbc_per_ul": 8.0e3,
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Bone RC, Balk RA, Cerra FB, et al.",
    "doi": "10.1378/chest.101.6.1644",
    "id": "bone-1992",
    "source": "Chest. 1992;101(6):1644-1655",
    "title": "Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis"
  },
  "formula": "sirs",
  "formula_expression": "SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4",
  "max_score": 4,
  "temperature_c": 37.0,
  "heart_rate_bpm": 80,
  "respiratory_rate": 16,
  "sirs_criteria_met": 0,
  "sirs_present": false
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• SOFA — Compute the Vincent 1996 SOFA score from PaO2/FiO2, platelets, bilirubin, MAP and adrenergic agents, GCS, and creatinine or urine output.
• qSOFA — Compute the Sepsis-3 qSOFA score from respiratory rate, caller-assigned altered mentation, and systolic blood pressure.

Payment

Required query parameters must be present and valid. Invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• Invalid query parameters return HTTP 400 before settlement. You are not charged.
• Settlement finishes before the tool executes (paymentFlow upfront). Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.