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Nama 2022 BRUE risk probabilities

BRUE 2.0

Compute the Nama 2022 Supplemental Table 7 logistic probabilities of a serious underlying diagnosis and of event recurrence from age in days, similar-event history, abnormal medical history, prematurity, event clusters, color change, abnormal respiratory pattern, and tone change.

LIVE $0.005 USDC GET /api/calc/brue_2

Markdown: /docs/brue-2.md · Canonical: https://magentlab.com/docs/brue-2

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Nama 2022 Supplemental Table 7 logistic probabilities of a serious underlying diagnosis and of event recurrence from age in days, similar-event history, abnormal medical history, prematurity, event clusters, color change, abnormal respiratory pattern, and tone change.

When to use

When an agent already has a brief resolved unexplained event and needs the published Nama 2022 probabilities. Do not invent an admission cutoff. magent does not examine the infant.

When not to use

• Not a medical device. Not a diagnosis.
• Nama 2022 Supplemental Table 7 logistic models only. magent does not apply a definition box and does not invent an admission cutoff.
• The caller assigns that the infant already meets a brief resolved unexplained event and assigns every flag. magent does not examine the infant or take a history.
• Age is 0-364 days. Recurrence in the derivation cohort was during the index emergency or hospital visit.
• Abnormal respiratory pattern and tone change have negative recurrence coefficients as published. Nama 2022 publishes no low or high percent cutoff.

Formula

Ls = -3.75 + 0.56*history_of_similar_event + 0.65*abnormal_medical_history + 0.0025*age_days; Lr = -2.44 + 0.46*prematurity + 0.58*history_of_similar_event + 1.17*history_of_event_clusters + 0.36*color_change - 0.32*abnormal_respiratory_pattern - 0.31*tone_change (Nama 2022 Supplemental Table 7); estimated_serious_diagnosis_percent = 100 * exp(Ls) / (1 + exp(Ls)); estimated_event_recurrence_percent = 100 * exp(Lr) / (1 + exp(Lr))

Citation

Title

Risk Prediction After a Brief Resolved Unexplained Event

Authors

Nama N, Hall M, Neuman M, et al.

Source

Hosp Pediatr. 2022;12(9):772-785

DOI

10.1542/hpeds.2022-006637

Worked example

Also searched as

• BRUE 2.0
• Nama 2022 BRUE
• brief resolved unexplained event risk
• serious diagnosis after BRUE
• BRUE recurrence probability
• Nama Hospital Pediatrics BRUE
• infant BRUE logistic risk
• BRUE event recurrence

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/brue_2?age_days=90&history_of_similar_event=false&abnormal_medical_history=false&prematurity=false&history_of_event_clusters=false&color_change=false&abnormal_respiratory_pattern=false&tone_change=false

Full URL: https://api.magentlab.com/api/calc/brue_2?age_days=90&history_of_similar_event=false&abnormal_medical_history=false&prematurity=false&history_of_event_clusters=false&color_change=false&abnormal_respiratory_pattern=false&tone_change=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/brue_2?age_days=90&history_of_similar_event=false&abnormal_medical_history=false&prematurity=false&history_of_event_clusters=false&color_change=false&abnormal_respiratory_pattern=false&tone_change=false"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/brue_2 Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "abnormal_medical_history": "false",
      "abnormal_respiratory_pattern": "false",
      "age_days": "90",
      "color_change": "false",
      "history_of_event_clusters": "false",
      "history_of_similar_event": "false",
      "prematurity": "false",
      "tone_change": "false"
    },
    {
      "abnormal_medical_history": "false",
      "abnormal_respiratory_pattern": "false",
      "age_days": "90",
      "color_change": "false",
      "history_of_event_clusters": "false",
      "history_of_similar_event": "false",
      "prematurity": "false",
      "tone_change": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/brue_2",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Nama N, Hall M, Neuman M, et al.",
        "doi": "10.1542/hpeds.2022-006637",
        "id": "nama-2022",
        "pmid": "35965279",
        "source": "Hosp Pediatr. 2022;12(9):772-785",
        "title": "Risk Prediction After a Brief Resolved Unexplained Event"
      },
      "formula": "brue_2",
      "formula_expression": "Ls = -3.75 + 0.56*history_of_similar_event + 0.65*abnormal_medical_history + 0.0025*age_days; Lr = -2.44 + 0.46*prematurity + 0.58*history_of_similar_event + 1.17*history_of_event_clusters + 0.36*color_change - 0.32*abnormal_respiratory_pattern - 0.31*tone_change (Nama 2022 Supplemental Table 7); estimated_serious_diagnosis_percent = 100 * exp(Ls) / (1 + exp(Ls)); estimated_event_recurrence_percent = 100 * exp(Lr) / (1 + exp(Lr))",
      "abnormal_medical_history": false,
      "abnormal_respiratory_pattern": false,
      "age_days": 90,
      "color_change": false,
      "estimated_event_recurrence_percent": 8.02,
      "estimated_serious_diagnosis_percent": 2.86,
      "event_recurrence_logit": -2.44,
      "history_of_event_clusters": false,
      "history_of_similar_event": false,
      "prematurity": false,
      "serious_diagnosis_logit": -3.525,
      "tone_change": false
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Nama N, Hall M, Neuman M, et al.",
        "doi": "10.1542/hpeds.2022-006637",
        "id": "nama-2022",
        "pmid": "35965279",
        "source": "Hosp Pediatr. 2022;12(9):772-785",
        "title": "Risk Prediction After a Brief Resolved Unexplained Event"
      },
      "formula": "brue_2",
      "formula_expression": "Ls = -3.75 + 0.56*history_of_similar_event + 0.65*abnormal_medical_history + 0.0025*age_days; Lr = -2.44 + 0.46*prematurity + 0.58*history_of_similar_event + 1.17*history_of_event_clusters + 0.36*color_change - 0.32*abnormal_respiratory_pattern - 0.31*tone_change (Nama 2022 Supplemental Table 7); estimated_serious_diagnosis_percent = 100 * exp(Ls) / (1 + exp(Ls)); estimated_event_recurrence_percent = 100 * exp(Lr) / (1 + exp(Lr))",
      "abnormal_medical_history": false,
      "abnormal_respiratory_pattern": false,
      "age_days": 90,
      "color_change": false,
      "estimated_event_recurrence_percent": 8.02,
      "estimated_serious_diagnosis_percent": 2.86,
      "event_recurrence_logit": -2.44,
      "history_of_event_clusters": false,
      "history_of_similar_event": false,
      "prematurity": false,
      "serious_diagnosis_logit": -3.525,
      "tone_change": false
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Nama N, Hall M, Neuman M, et al.",
    "doi": "10.1542/hpeds.2022-006637",
    "id": "nama-2022",
    "pmid": "35965279",
    "source": "Hosp Pediatr. 2022;12(9):772-785",
    "title": "Risk Prediction After a Brief Resolved Unexplained Event"
  },
  "formula": "brue_2",
  "formula_expression": "Ls = -3.75 + 0.56*history_of_similar_event + 0.65*abnormal_medical_history + 0.0025*age_days; Lr = -2.44 + 0.46*prematurity + 0.58*history_of_similar_event + 1.17*history_of_event_clusters + 0.36*color_change - 0.32*abnormal_respiratory_pattern - 0.31*tone_change (Nama 2022 Supplemental Table 7); estimated_serious_diagnosis_percent = 100 * exp(Ls) / (1 + exp(Ls)); estimated_event_recurrence_percent = 100 * exp(Lr) / (1 + exp(Lr))",
  "abnormal_medical_history": false,
  "abnormal_respiratory_pattern": false,
  "age_days": 90,
  "color_change": false,
  "estimated_event_recurrence_percent": 8.02,
  "estimated_serious_diagnosis_percent": 2.86,
  "event_recurrence_logit": -2.44,
  "history_of_event_clusters": false,
  "history_of_similar_event": false,
  "prematurity": false,
  "serious_diagnosis_logit": -3.525,
  "tone_change": false
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• BRUE — Apply the Tieder 2016 AAP BRUE definition and return feature_count (0-4) and whether the published definition box holds (brue).

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.