DASH recurrent VTE

DASH

Compute the Tosetto 2012 DASH score (abnormal D-dimer after stopping anticoagulation, age <50, male sex, hormone use at the initial VTE in women) and return the published recurrence band.

LIVE $0.005 USDC GET /api/calc/dash

Markdown: /docs/dash.md · Canonical: https://magentlab.com/docs/dash

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Tosetto 2012 DASH score (abnormal D-dimer after stopping anticoagulation, age <50, male sex, hormone use at the initial VTE in women) and return the published recurrence band.

When to use

When an agent needs the published Tosetto 2012 DASH arithmetic after unprovoked VTE and must not invent a duration-of-anticoagulation decision.

When not to use

Not a medical device. magent does not diagnose recurrent VTE or assay D-dimer.
Not a duration-of-anticoagulation order and not a stop-or-continue anticoagulation protocol. Recurrence bands are published Tosetto 2012 groups, not treatment instructions.
Age scores only when <50 years (Tosetto 2012 abstract). Age 50 does not score.
Hormone use at the initial VTE scores -2 in women only. Male with hormone_use=true is rejected.
Abnormal D-dimer is after stopping anticoagulation as published. Percents are not returned in the JSON body.

Formula

DASH = 2*abnormal_d_dimer + 1*(age<50) + 1*male + (-2)*hormone_use(female only); max 4; recurrence_band <=1 / 2 / >=3

Citation

Title: Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH)
Authors: Tosetto A, Iorio A, Marcucci M, et al.
Source: J Thromb Haemost. 2012;10(6):1019-1025
DOI: 10.1111/j.1538-7836.2012.04735.x

Worked example

Age 60 female, no D-dimer, no hormone use

Given: abnormal_d_dimer=falseage=60hormone_use=falsesex=female

abnormal_d_dimer false → 0; age 60 is not <50 → 0; female → 0; hormone_use false → 0
Score = 0 (max 4); recurrence_band <=1

Age 40 male with abnormal D-dimer

Given: abnormal_d_dimer=trueage=40hormone_use=falsesex=male

abnormal_d_dimer → 2; age 40 < 50 → 1; male → 1; hormone_use false → 0
Score = 4 (max 4); recurrence_band >=3

Also searched as

DASH score
DASH VTE
Tosetto DASH
recurrent VTE DASH
DASH prediction score
unprovoked VTE recurrence

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/dash?age=60&sex=female&abnormal_d_dimer=false&hormone_use=false

Full URL: https://api.magentlab.com/api/calc/dash?age=60&sex=female&abnormal_d_dimer=false&hormone_use=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/dash?age=60&sex=female&abnormal_d_dimer=false&hormone_use=false"

Parameters

Name	Type	Required	Description
`age`	integer	required	Age in years (18-120). Scores 1 when age is <50 (Tosetto 2012). Age 50 does not score.
`sex`	string	required · female, male	female or male. Male scores 1. Hormone use applies only when female.
`abnormal_d_dimer`	boolean	required	Abnormal D-dimer after stopping anticoagulation (Tosetto 2012). true or false. 2 points if true.
`hormone_use`	boolean	required	Hormone use at the initial VTE. Required. Scores -2 only when sex is female and true. Must be false when sex is male.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/dash Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "abnormal_d_dimer": "false",
      "age": "60",
      "hormone_use": "false",
      "sex": "female"
    },
    {
      "abnormal_d_dimer": "false",
      "age": "60",
      "hormone_use": "false",
      "sex": "female"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/dash",
  "items": [
    {
      "components": [
        {
          "factor": "abnormal_d_dimer",
          "points": 0,
          "present": false
        },
        {
          "value": 60,
          "factor": "age_lt_50",
          "points": 0,
          "present": false
        },
        {
          "factor": "male",
          "points": 0,
          "present": false
        },
        {
          "factor": "hormone_use",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "age_years": 60,
      "citation": {
        "authors": "Tosetto A, Iorio A, Marcucci M, et al.",
        "doi": "10.1111/j.1538-7836.2012.04735.x",
        "id": "tosetto-2012",
        "pmid": "22489957",
        "source": "J Thromb Haemost. 2012;10(6):1019-1025",
        "title": "Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH)"
      },
      "formula": "dash",
      "formula_expression": "DASH = 2*abnormal_d_dimer + 1*(age<50) + 1*male + (-2)*hormone_use(female only); max 4; recurrence_band <=1 / 2 / >=3",
      "max_score": 4,
      "score": 0,
      "sex": "female",
      "recurrence_band": "<=1"
    },
    {
      "components": [
        {
          "factor": "abnormal_d_dimer",
          "points": 0,
          "present": false
        },
        {
          "value": 60,
          "factor": "age_lt_50",
          "points": 0,
          "present": false
        },
        {
          "factor": "male",
          "points": 0,
          "present": false
        },
        {
          "factor": "hormone_use",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "age_years": 60,
      "citation": {
        "authors": "Tosetto A, Iorio A, Marcucci M, et al.",
        "doi": "10.1111/j.1538-7836.2012.04735.x",
        "id": "tosetto-2012",
        "pmid": "22489957",
        "source": "J Thromb Haemost. 2012;10(6):1019-1025",
        "title": "Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH)"
      },
      "formula": "dash",
      "formula_expression": "DASH = 2*abnormal_d_dimer + 1*(age<50) + 1*male + (-2)*hormone_use(female only); max 4; recurrence_band <=1 / 2 / >=3",
      "max_score": 4,
      "score": 0,
      "sex": "female",
      "recurrence_band": "<=1"
    }
  ]
}

Response

Field	Type	Description
`formula`	string	dash
`formula_expression`	string	Exact expression used
`score`	integer	DASH points from -2 to 4
`max_score`	integer	4
`recurrence_band`	string	Tosetto 2012 published annualized-recurrence group: <=1, 2, or >=3. Percents are not returned. Not a stop-or-continue anticoagulation order.
`age_years`	integer	Age used for the <50 criterion
`sex`	string	female or male
`components`	array	Per-factor points
`citation`	object	Tosetto 2012 J Thromb Haemost citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "components": [
    {
      "factor": "abnormal_d_dimer",
      "points": 0,
      "present": false
    },
    {
      "value": 60,
      "factor": "age_lt_50",
      "points": 0,
      "present": false
    },
    {
      "factor": "male",
      "points": 0,
      "present": false
    },
    {
      "factor": "hormone_use",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "age_years": 60,
  "citation": {
    "authors": "Tosetto A, Iorio A, Marcucci M, et al.",
    "doi": "10.1111/j.1538-7836.2012.04735.x",
    "id": "tosetto-2012",
    "pmid": "22489957",
    "source": "J Thromb Haemost. 2012;10(6):1019-1025",
    "title": "Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH)"
  },
  "formula": "dash",
  "formula_expression": "DASH = 2*abnormal_d_dimer + 1*(age<50) + 1*male + (-2)*hormone_use(female only); max 4; recurrence_band <=1 / 2 / >=3",
  "max_score": 4,
  "score": 0,
  "sex": "female",
  "recurrence_band": "<=1"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_age`	age must be an integer from 18 to 120 Returned before settlement; you are not charged.
400	`invalid_sex`	sex must be female or male Returned before settlement; you are not charged.
400	`invalid_flag`	boolean clinical flags must be true or false Returned before settlement; you are not charged.
400	`invalid_dash_hormone`	hormone_use may be true only when sex is female (Tosetto 2012 DASH). Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

Wells PE — Compute the Wells pulmonary-embolism probability score and return three-tier and two-tier bands.
Wells DVT — Compute the Wells deep-vein thrombosis probability score and return three-tier and two-tier bands.
YEARS algorithm — Apply the van der Hulle 2017 YEARS algorithm: count three caller-assigned items and return whether PE is excluded at the published D-dimer threshold.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.