MAGENT

Hematology · LIVE

Duval 2010 AML score (Table 5)

Duval AML

Sum the Duval 2010 AML Table 5 points and return risk_group 0, 1, 2, or ge_3 (scores ≥3 share one group).

LIVE $0.005 USDC GET /api/calc/duval_aml

Markdown: /docs/duval-aml.md · Canonical: https://magentlab.com/docs/duval-aml

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Sum the Duval 2010 AML Table 5 points and return risk_group 0, 1, 2, or ge_3 (scores ≥3 share one group).

When to use

When an agent needs the published Duval 2010 AML (not ALL) Table 5 point total from caller-assigned categories and must not invent a transplant listing, karyotype parse, or ALL score.

When not to use

  • Not a medical device and not a diagnosis. Not a transplant listing. magent does not examine the patient.
  • This is Duval 2010 Table 5 for AML only. It does not implement the ALL table in the same paper.
  • magent does not read a karyotype string or HLA type. The caller assigns disease_group, ECOG/SWOG cytogenetics (poor vs good/intermediate), and the Table 5 three-level hla_match.
  • magent does not collect numeric Karnofsky or Lansky. kps_lt_90 is a caller-assigned flag.
  • Table 5 groups scores ≥3 together. Published 3-year overall survival in the derivation cohort was 42% at score 0 and 6% at score ≥3. Those figures are not returned on the JSON 200.

Formula

Duval AML Table 5 = disease_group (pif_or_cr1_gt_6mo 0, cr1_lt_6mo 1) + cytogenetics (good_or_intermediate 0, poor 1) + hla_match (sibling_or_matched_unrelated 0, mismatched_unrelated 1, related_other 2) + circulating_blasts 1 + kps_lt_90 1; Duval 2010 AML only (not ALL); max 6; risk_group 0 / 1 / 2 / ge_3

Citation

Title
Hematopoietic Stem-Cell Transplantation for Acute Leukemia in Relapse or Primary Induction Failure
Authors
Duval M, Klein JP, He W, et al
Source
J Clin Oncol. 2010;28(23):3730-3738
DOI
10.1200/JCO.2010.28.8852

Worked example

All favorable AML Table 5 categories

Given: circulating_blasts=falsecytogenetics=good_or_intermediatedisease_group=pif_or_cr1_gt_6mohla_match=sibling_or_matched_unrelatedkps_lt_90=false

  1. disease_group pif_or_cr1_gt_6mo → 0; cytogenetics good_or_intermediate → 0; hla_match sibling_or_matched_unrelated → 0; circulating_blasts false → 0; kps_lt_90 false → 0
  2. Score = 0 (max 6); risk_group = 0

Maximum published AML Table 5 score

Given: circulating_blasts=truecytogenetics=poordisease_group=cr1_lt_6mohla_match=related_otherkps_lt_90=true

  1. cr1_lt_6mo → 1; poor cytogenetics → 1; related_other → 2; circulating_blasts → 1; kps_lt_90 → 1
  2. Score = 6 (max 6); risk_group = ge_3

Also searched as

  • Duval AML score
  • Duval 2010 AML
  • CIBMTR AML score
  • AML transplant score Duval
  • Duval Table 5 AML
  • AML PIF relapse HCT score
  • Duval CIBMTR AML
  • hematopoietic stem-cell AML score

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/duval_aml?disease_group=pif_or_cr1_gt_6mo&cytogenetics=good_or_intermediate&hla_match=sibling_or_matched_unrelated&circulating_blasts=false&kps_lt_90=false

Full URL: https://api.magentlab.com/api/calc/duval_aml?disease_group=pif_or_cr1_gt_6mo&cytogenetics=good_or_intermediate&hla_match=sibling_or_matched_unrelated&circulating_blasts=false&kps_lt_90=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/duval_aml?disease_group=pif_or_cr1_gt_6mo&cytogenetics=good_or_intermediate&hla_match=sibling_or_matched_unrelated&circulating_blasts=false&kps_lt_90=false"

Parameters

Name Type Required Description
disease_group string required · pif_or_cr1_gt_6mo, cr1_lt_6mo Duval 2010 AML Table 5 disease status as assigned by the caller. pif_or_cr1_gt_6mo is primary induction failure or duration of first CR >6 months and scores 0. cr1_lt_6mo is duration of first CR <6 months and scores 1. magent does not date remissions.
cytogenetics string required · good_or_intermediate, poor ECOG/SWOG cytogenetic risk as assigned by the caller (Duval 2010). poor is −5/del(5q), −7/del(7q), inv(3q), abn11q, 20q or 21q, del(9q), t(6;9), t(9;22), abn17p, or complex (≥3 abnormalities) and scores 1. good_or_intermediate is everything else in that classification and scores 0. magent does not read a karyotype string.
hla_match string required · sibling_or_matched_unrelated, mismatched_unrelated, related_other Duval 2010 AML Table 5 donor HLA match as assigned by the caller (not a flattened 0/1 donor flag). sibling_or_matched_unrelated is HLA-identical sibling or well matched or partially matched unrelated and scores 0. mismatched_unrelated scores 1. related_other is related other than HLA-identical sibling and scores 2. magent does not HLA-type.
circulating_blasts boolean required Circulating blasts present as assigned by the caller (Duval 2010 AML Table 5). true scores 1. magent does not count blasts.
kps_lt_90 boolean required Karnofsky or Lansky <90 as assigned by the caller (Duval 2010 AML Table 5). true scores 1. magent does not collect numeric KPS or Lansky.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/duval_aml Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "circulating_blasts": "false",
      "cytogenetics": "good_or_intermediate",
      "disease_group": "pif_or_cr1_gt_6mo",
      "hla_match": "sibling_or_matched_unrelated",
      "kps_lt_90": "false"
    },
    {
      "circulating_blasts": "false",
      "cytogenetics": "good_or_intermediate",
      "disease_group": "pif_or_cr1_gt_6mo",
      "hla_match": "sibling_or_matched_unrelated",
      "kps_lt_90": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/duval_aml",
  "items": [
    {
      "components": [
        {
          "value": "pif_or_cr1_gt_6mo",
          "factor": "disease_group",
          "points": 0,
          "present": false
        },
        {
          "value": "good_or_intermediate",
          "factor": "cytogenetics",
          "points": 0,
          "present": false
        },
        {
          "value": "sibling_or_matched_unrelated",
          "factor": "hla_match",
          "points": 0,
          "present": false
        },
        {
          "factor": "circulating_blasts",
          "points": 0,
          "present": false
        },
        {
          "factor": "kps_lt_90",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Duval M, Klein JP, He W, et al",
        "doi": "10.1200/JCO.2010.28.8852",
        "id": "duval-2010",
        "pmid": "20625126",
        "source": "J Clin Oncol. 2010;28(23):3730-3738",
        "title": "Hematopoietic Stem-Cell Transplantation for Acute Leukemia in Relapse or Primary Induction Failure"
      },
      "formula": "duval_aml",
      "formula_expression": "Duval AML Table 5 = disease_group (pif_or_cr1_gt_6mo 0, cr1_lt_6mo 1) + cytogenetics (good_or_intermediate 0, poor 1) + hla_match (sibling_or_matched_unrelated 0, mismatched_unrelated 1, related_other 2) + circulating_blasts 1 + kps_lt_90 1; Duval 2010 AML only (not ALL); max 6; risk_group 0 / 1 / 2 / ge_3",
      "max_score": 6,
      "score": 0,
      "risk_group": "0",
      "circulating_blasts": false,
      "cytogenetics": "good_or_intermediate",
      "disease_group": "pif_or_cr1_gt_6mo",
      "hla_match": "sibling_or_matched_unrelated",
      "kps_lt_90": false
    },
    {
      "components": [
        {
          "value": "pif_or_cr1_gt_6mo",
          "factor": "disease_group",
          "points": 0,
          "present": false
        },
        {
          "value": "good_or_intermediate",
          "factor": "cytogenetics",
          "points": 0,
          "present": false
        },
        {
          "value": "sibling_or_matched_unrelated",
          "factor": "hla_match",
          "points": 0,
          "present": false
        },
        {
          "factor": "circulating_blasts",
          "points": 0,
          "present": false
        },
        {
          "factor": "kps_lt_90",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Duval M, Klein JP, He W, et al",
        "doi": "10.1200/JCO.2010.28.8852",
        "id": "duval-2010",
        "pmid": "20625126",
        "source": "J Clin Oncol. 2010;28(23):3730-3738",
        "title": "Hematopoietic Stem-Cell Transplantation for Acute Leukemia in Relapse or Primary Induction Failure"
      },
      "formula": "duval_aml",
      "formula_expression": "Duval AML Table 5 = disease_group (pif_or_cr1_gt_6mo 0, cr1_lt_6mo 1) + cytogenetics (good_or_intermediate 0, poor 1) + hla_match (sibling_or_matched_unrelated 0, mismatched_unrelated 1, related_other 2) + circulating_blasts 1 + kps_lt_90 1; Duval 2010 AML only (not ALL); max 6; risk_group 0 / 1 / 2 / ge_3",
      "max_score": 6,
      "score": 0,
      "risk_group": "0",
      "circulating_blasts": false,
      "cytogenetics": "good_or_intermediate",
      "disease_group": "pif_or_cr1_gt_6mo",
      "hla_match": "sibling_or_matched_unrelated",
      "kps_lt_90": false
    }
  ]
}

Response

Field Type Description
formula string duval_aml
formula_expression string Exact expression used
score integer Duval 2010 AML Table 5 points 0-6
max_score integer 6 (1+1+2+1+1)
risk_group string 0, 1, 2, or ge_3 when score is ≥3 (Duval 2010 Table 5 note). Not a transplant listing. Not a diagnosis. Not the ALL table.
disease_group string Caller-assigned pif_or_cr1_gt_6mo or cr1_lt_6mo
cytogenetics string Caller-assigned good_or_intermediate or poor
hla_match string Caller-assigned sibling_or_matched_unrelated, mismatched_unrelated, or related_other
circulating_blasts boolean Caller-assigned circulating-blasts flag used
kps_lt_90 boolean Caller-assigned Karnofsky or Lansky <90 flag used
components array Per-factor points
citation object Duval et al. J Clin Oncol 2010 citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "components": [
    {
      "value": "pif_or_cr1_gt_6mo",
      "factor": "disease_group",
      "points": 0,
      "present": false
    },
    {
      "value": "good_or_intermediate",
      "factor": "cytogenetics",
      "points": 0,
      "present": false
    },
    {
      "value": "sibling_or_matched_unrelated",
      "factor": "hla_match",
      "points": 0,
      "present": false
    },
    {
      "factor": "circulating_blasts",
      "points": 0,
      "present": false
    },
    {
      "factor": "kps_lt_90",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Duval M, Klein JP, He W, et al",
    "doi": "10.1200/JCO.2010.28.8852",
    "id": "duval-2010",
    "pmid": "20625126",
    "source": "J Clin Oncol. 2010;28(23):3730-3738",
    "title": "Hematopoietic Stem-Cell Transplantation for Acute Leukemia in Relapse or Primary Induction Failure"
  },
  "formula": "duval_aml",
  "formula_expression": "Duval AML Table 5 = disease_group (pif_or_cr1_gt_6mo 0, cr1_lt_6mo 1) + cytogenetics (good_or_intermediate 0, poor 1) + hla_match (sibling_or_matched_unrelated 0, mismatched_unrelated 1, related_other 2) + circulating_blasts 1 + kps_lt_90 1; Duval 2010 AML only (not ALL); max 6; risk_group 0 / 1 / 2 / ge_3",
  "max_score": 6,
  "score": 0,
  "risk_group": "0",
  "circulating_blasts": false,
  "cytogenetics": "good_or_intermediate",
  "disease_group": "pif_or_cr1_gt_6mo",
  "hla_match": "sibling_or_matched_unrelated",
  "kps_lt_90": false
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_flag boolean clinical flags must be true or false Returned before settlement; you are not charged.
400 invalid_duval each Duval 2010 AML item must be a published Table 5 category. Returned before settlement; you are not charged.
400 invalid_hla_match hla_match must be sibling_or_matched_unrelated, mismatched_unrelated, or related_other (Duval 2010). Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • Karnofsky — Return the Karnofsky 1949 Performance Status 10-100 from a caller-assigned integer, with a stable label.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.