MAGENT

Kidney · LIVE

Fuhrman nuclear grade (1982)

Fuhrman

Echo the caller-assigned Fuhrman 1982 nuclear grade (1-4) with the published nuclear-feature description. magent does not read slides. Not WHO/ISUP 2016.

LIVE $0.005 USDC GET /api/calc/fuhrman

Markdown: /docs/fuhrman.md · Canonical: https://magentlab.com/docs/fuhrman

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Echo the caller-assigned Fuhrman 1982 nuclear grade (1-4) with the published nuclear-feature description. magent does not read slides. Not WHO/ISUP 2016.

When to use

When an agent already has a Fuhrman 1982 nuclear grade as assigned by the caller and needs the published grade description. magent does not read slides, assign grade from histology, or map to WHO/ISUP 2016.

When not to use

  • Not a medical device. magent does not read slides.
  • The caller assigns Fuhrman 1982 nuclear grade 1-4. magent does not grade nuclei, measure nuclear diameter, or inspect nucleoli.
  • Fuhrman 1982 four nuclear grades only. Not WHO/ISUP 2016. This tool does not convert Fuhrman grade to WHO/ISUP grade.
  • Not an RCC diagnosis. Not a treatment or nephrectomy order. No survival bands.

Formula

fuhrman_grade in {1, 2, 3, 4} as assigned by the caller (Fuhrman 1982 four nuclear grades in order of increasing nuclear size, irregularity, and nucleolar prominence). Not WHO/ISUP 2016. magent does not read slides.

Citation

Title
Prognostic significance of morphologic parameters in renal cell carcinoma
Authors
Fuhrman SA, Lasky LC, Limas C
Source
Am J Surg Pathol. 1982;6(7):655-663
DOI
10.1097/00000478-198210000-00007

Worked example

Grade 1 small uniform nuclei

Given: fuhrman_grade=1

  1. fuhrman_grade 1 as assigned by the caller
  2. small (~10 μm) round, uniform nuclei; nucleoli absent or inconspicuous

Grade 4 bizarre multilobed nuclei

Given: fuhrman_grade=4

  1. fuhrman_grade 4 as assigned by the caller
  2. as for grade 3 with bizarre often multilobed nuclei ± spindle cells

Also searched as

  • Fuhrman grade
  • Fuhrman nuclear grade
  • Fuhrman 1982
  • RCC nuclear grade
  • renal cell carcinoma grade
  • Fuhrman 1-4
  • nuclear grading RCC
  • Fuhrman nucleolar grade

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/fuhrman?fuhrman_grade=1

Full URL: https://api.magentlab.com/api/calc/fuhrman?fuhrman_grade=1

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/fuhrman?fuhrman_grade=1"

Parameters

Name Type Required Description
fuhrman_grade integer required Fuhrman 1982 nuclear grade 1-4 as assigned by the caller (1 small ~10 μm round uniform nuclei, nucleoli absent or inconspicuous; 2 larger ~15 μm nuclei with outline irregularities, nucleoli visible at ×400; 3 even larger ~20 μm with obvious irregular outline, nucleoli prominent at ×100; 4 as for grade 3 with bizarre often multilobed nuclei ± spindle cells). Integer 1-4 only; reject 0, 5, 1.5, and roman I. Not WHO/ISUP 2016. magent does not read slides.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/fuhrman Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "fuhrman_grade": "1"
    },
    {
      "fuhrman_grade": "1"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/fuhrman",
  "items": [
    {
      "description": "Small (~10 μm) round, uniform nuclei; nucleoli absent or inconspicuous",
      "components": [
        {
          "factor": "grade_1",
          "met": true
        },
        {
          "factor": "grade_2",
          "met": false
        },
        {
          "factor": "grade_3",
          "met": false
        },
        {
          "factor": "grade_4",
          "met": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Fuhrman SA, Lasky LC, Limas C",
        "doi": "10.1097/00000478-198210000-00007",
        "id": "fuhrman-1982",
        "pmid": "7180965",
        "source": "Am J Surg Pathol. 1982;6(7):655-663",
        "title": "Prognostic significance of morphologic parameters in renal cell carcinoma"
      },
      "formula": "fuhrman",
      "formula_expression": "fuhrman_grade in {1, 2, 3, 4} as assigned by the caller (Fuhrman 1982 four nuclear grades in order of increasing nuclear size, irregularity, and nucleolar prominence). Not WHO/ISUP 2016. magent does not read slides.",
      "fuhrman_grade": 1
    },
    {
      "description": "Small (~10 μm) round, uniform nuclei; nucleoli absent or inconspicuous",
      "components": [
        {
          "factor": "grade_1",
          "met": true
        },
        {
          "factor": "grade_2",
          "met": false
        },
        {
          "factor": "grade_3",
          "met": false
        },
        {
          "factor": "grade_4",
          "met": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Fuhrman SA, Lasky LC, Limas C",
        "doi": "10.1097/00000478-198210000-00007",
        "id": "fuhrman-1982",
        "pmid": "7180965",
        "source": "Am J Surg Pathol. 1982;6(7):655-663",
        "title": "Prognostic significance of morphologic parameters in renal cell carcinoma"
      },
      "formula": "fuhrman",
      "formula_expression": "fuhrman_grade in {1, 2, 3, 4} as assigned by the caller (Fuhrman 1982 four nuclear grades in order of increasing nuclear size, irregularity, and nucleolar prominence). Not WHO/ISUP 2016. magent does not read slides.",
      "fuhrman_grade": 1
    }
  ]
}

Response

Field Type Description
formula string fuhrman
formula_expression string Published Fuhrman 1982 nuclear-grade rule
fuhrman_grade integer Caller-assigned Fuhrman 1982 nuclear grade 1-4
description string Fuhrman 1982 nuclear-feature wording for that grade
components array Per-grade Tree rows grade_1, grade_2, grade_3, grade_4 with factor and met; exactly one is met
citation object Fuhrman 1982 Am J Surg Pathol citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "description": "Small (~10 μm) round, uniform nuclei; nucleoli absent or inconspicuous",
  "components": [
    {
      "factor": "grade_1",
      "met": true
    },
    {
      "factor": "grade_2",
      "met": false
    },
    {
      "factor": "grade_3",
      "met": false
    },
    {
      "factor": "grade_4",
      "met": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Fuhrman SA, Lasky LC, Limas C",
    "doi": "10.1097/00000478-198210000-00007",
    "id": "fuhrman-1982",
    "pmid": "7180965",
    "source": "Am J Surg Pathol. 1982;6(7):655-663",
    "title": "Prognostic significance of morphologic parameters in renal cell carcinoma"
  },
  "formula": "fuhrman",
  "formula_expression": "fuhrman_grade in {1, 2, 3, 4} as assigned by the caller (Fuhrman 1982 four nuclear grades in order of increasing nuclear size, irregularity, and nucleolar prominence). Not WHO/ISUP 2016. magent does not read slides.",
  "fuhrman_grade": 1
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_fuhrman fuhrman_grade must be 1, 2, 3, or 4 (Fuhrman 1982 nuclear grade). Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • R.E.N.A.L. nephrometry — Sum the Kutikov 2009 R.E.N.A.L. nephrometry score for a renal mass from four caller-assigned published item points (radius, exophytic/endophytic, nearness, location) and return the integer total (4–12) plus anterior and hilar descriptors. Does not return complexity bands.
  • Motzer — Sum the Motzer 1999 MSKCC adverse factors for advanced RCC and return favorable (0), intermediate (1–2), or poor (≥3). Motzer 1999 reported median survival of 20, 10, and 4 months in those interferon-era groups as published cohort results, not a predicted survival.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.