Hematology · LIVE
Ganzoni iron deficit
Compute the Ganzoni 1970 iron deficit from weight, measured hemoglobin, a caller-supplied target hemoglobin, and depot iron stores.
Markdown: /docs/ganzoni.md · Canonical: https://magentlab.com/docs/ganzoni
Not a medical device. Not a diagnosis, dose, or listing recommendation.
What it computes
Compute the Ganzoni 1970 iron deficit from weight, measured hemoglobin, a caller-supplied target hemoglobin, and depot iron stores.
When to use
When an agent needs the published Ganzoni milligram deficit and must not invent a target hemoglobin, depot iron, or an IV iron product order.
When not to use
- Not an IV iron product dose or order. magent does not pick target hemoglobin or depot iron.
- Not a diagnosis of iron deficiency.
Formula
iron_deficit_mg = weight_kg * (target_hemoglobin_g_dl - hemoglobin_g_dl) * 2.4 + iron_stores_mg
Citation
- Authors
- Ganzoni AM
- Source
- Schweiz Med Wochenschr. 1970;100(7):301-303
- DOI
- none
Worked example
70 kg, Hb 8 to 15 g/dL, stores 500 mg
Given:
hemoglobin_g_dl=8iron_stores_mg=500target_hemoglobin_g_dl=15weight_kg=70
- iron_deficit = 70 * (15 - 8) * 2.4 + 500 = 1176 + 500 = 1676.0 mg
70 kg, Hb 8 to 15 g/dL, stores 0 mg
Given:
hemoglobin_g_dl=8iron_stores_mg=0target_hemoglobin_g_dl=15weight_kg=70
- iron_deficit = 70 * (15 - 8) * 2.4 + 0 = 1176.0 mg
Also searched as
- Ganzoni
- iron deficit
- iron deficit formula
- Ganzoni formula
- hemoglobin iron stores
- depot iron
Try
Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.
/api/calc/ganzoni?weight_kg=70&hemoglobin_g_dl=8&target_hemoglobin_g_dl=15&iron_stores_mg=500
Full URL: https://api.magentlab.com/api/calc/ganzoni?weight_kg=70&hemoglobin_g_dl=8&target_hemoglobin_g_dl=15&iron_stores_mg=500
Call
Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params
return HTTP 400 before any quote or charge.
curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/ganzoni?weight_kg=70&hemoglobin_g_dl=8&target_hemoglobin_g_dl=15&iron_stores_mg=500"
Parameters
| Name | Type | Required | Description |
|---|---|---|---|
weight_kg |
number | optional | Weight in kilograms. Provide weight_kg or weight_lb. |
weight_lb |
number | optional | Weight in pounds. Converted as kg = lb * 0.45359237. |
hemoglobin_g_dl |
number | required | Measured hemoglobin in g/dL (3-22). This tool does not accept g/L. |
target_hemoglobin_g_dl |
number | required | Target hemoglobin in g/dL (7-18). Must be strictly greater than hemoglobin_g_dl. magent does not pick a target. |
iron_stores_mg |
number | required | Depot iron stores in mg (0-2000). Required; magent does not default a depot. |
Bulk (POST)
POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.
- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.
Example request (fixture)
{
"items": [
{
"hemoglobin_g_dl": "8",
"iron_stores_mg": "500",
"target_hemoglobin_g_dl": "15",
"weight_kg": "70"
},
{
"hemoglobin_g_dl": "8",
"iron_stores_mg": "500",
"target_hemoglobin_g_dl": "15",
"weight_kg": "70"
}
]
}
Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.
Example 200 (fixture)
{
"count": 2,
"path": "/api/calc/ganzoni",
"items": [
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Ganzoni AM",
"id": "ganzoni-1970",
"pmid": "5417430",
"source": "Schweiz Med Wochenschr. 1970;100(7):301-303",
"title": "Intravenous iron-dextran: therapeutic and experimental possibilities"
},
"formula": "ganzoni",
"formula_expression": "iron_deficit_mg = weight_kg * (target_hemoglobin_g_dl - hemoglobin_g_dl) * 2.4 + iron_stores_mg",
"weight_kg": 70.0,
"hemoglobin_g_dl": 8.0,
"iron_deficit_mg": 1676.0,
"iron_stores_mg": 500.0,
"target_hemoglobin_g_dl": 15.0
},
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Ganzoni AM",
"id": "ganzoni-1970",
"pmid": "5417430",
"source": "Schweiz Med Wochenschr. 1970;100(7):301-303",
"title": "Intravenous iron-dextran: therapeutic and experimental possibilities"
},
"formula": "ganzoni",
"formula_expression": "iron_deficit_mg = weight_kg * (target_hemoglobin_g_dl - hemoglobin_g_dl) * 2.4 + iron_stores_mg",
"weight_kg": 70.0,
"hemoglobin_g_dl": 8.0,
"iron_deficit_mg": 1676.0,
"iron_stores_mg": 500.0,
"target_hemoglobin_g_dl": 15.0
}
]
}
Response
| Field | Type | Description |
|---|---|---|
formula |
string | ganzoni |
formula_expression |
string | Exact expression used |
weight_kg |
number | Normalized weight in kg |
hemoglobin_g_dl |
number | Measured hemoglobin in g/dL |
target_hemoglobin_g_dl |
number | Target hemoglobin in g/dL used |
iron_stores_mg |
number | Depot iron stores in mg used |
iron_deficit_mg |
number | Iron deficit in mg, 1 decimal |
citation |
object | Ganzoni 1970 citation |
disclaimer |
string | Not-a-device notice |
Example JSON
Machine form of the same example. Frozen fixture. Not a live lookup.
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Ganzoni AM",
"id": "ganzoni-1970",
"pmid": "5417430",
"source": "Schweiz Med Wochenschr. 1970;100(7):301-303",
"title": "Intravenous iron-dextran: therapeutic and experimental possibilities"
},
"formula": "ganzoni",
"formula_expression": "iron_deficit_mg = weight_kg * (target_hemoglobin_g_dl - hemoglobin_g_dl) * 2.4 + iron_stores_mg",
"weight_kg": 70.0,
"hemoglobin_g_dl": 8.0,
"iron_deficit_mg": 1676.0,
"iron_stores_mg": 500.0,
"target_hemoglobin_g_dl": 15.0
}
Client errors (HTTP 400)
Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.
| HTTP | Code | When |
|---|---|---|
| 400 | invalid_weight |
weight_kg (1-500) or weight_lb (2-1100) is required Returned before settlement; you are not charged. |
| 400 | invalid_hemoglobin |
hemoglobin_g_l (30-220) or hemoglobin_g_dl (3-22) is required, not both. Returned before settlement; you are not charged. |
| 400 | invalid_target_hemoglobin |
target_hemoglobin_g_dl must be 7-18 and strictly greater than hemoglobin_g_dl. Returned before settlement; you are not charged. |
| 400 | invalid_iron_stores |
iron_stores_mg must be a number from 0 to 2000. Returned before settlement; you are not charged. |
| 400 | invalid_items |
POST body must be a JSON object with only an items array Returned before settlement; you are not charged. |
| 400 | invalid_item_count |
items must be an array of 1 to 25 objects Returned before settlement; you are not charged. |
| 400 | invalid_item |
each items entry must be a JSON object Returned before settlement; you are not charged. |
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Payment
Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64
PAYMENT-REQUIRED
header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake
and shared payment errors: Payments.
Stdio MCP: /docs/mcp.
Guarantees
- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.