Hamilton depression rating scale

HAM-D

Sum seventeen caller-assigned Hamilton 1960 items (eight integers 0-4 and nine integers 0-2) and return the published 0-50 total. Does not apply later total-score severity bands or the four excluded 21-item variables.

LIVE $0.005 USDC GET /api/calc/hamilton_depression

Markdown: /docs/hamilton-depression.md · Canonical: https://magentlab.com/docs/hamilton-depression

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

When to use

When an agent already has Hamilton 1960 integers in the published per-item ranges and needs the published 17-variable total. magent does not interview the patient, diagnose depression, score the later 21-item form, or apply later 0-7/8-16/17-23/≥24 cutoffs.

When not to use

Not a medical device and not a depression diagnosis or treatment order.
Each of the 17 variables is a caller-assigned integer in the Hamilton 1960 range for that item (0-4 five-point or 0-2 three-point). magent does not interview the patient.
This is Hamilton 1960's 17 scored variables only (max 50). Items 18-21 on that form (diurnal variation, depersonalization, paranoid symptoms, obsessional symptoms) are excluded from the scale in that paper. magent does not score later 21-item HAM-D forms that rate agitation 0-4 (max 52).
Hamilton 1960 published no total-score severity bands. This tool returns score and max_score only. It does not apply later 0-7/8-16/17-23/≥24 website or review cutoffs.
Hamilton 1960 summed two raters (or doubled a single rater) for comparability. magent sums the 17 caller-assigned integers only and does not double the total.

Formula

HAM-D = depressed_mood + guilt + suicide + insomnia_initial + insomnia_middle + insomnia_delayed + work_and_interests + retardation + agitation + anxiety_psychic + anxiety_somatic + somatic_gastrointestinal + somatic_general + genital_symptoms + hypochondriasis + insight + loss_of_weight; Hamilton 1960 17 variables (not items 18-21); 0-4 five-point for depressed_mood, guilt, suicide, work_and_interests, retardation, anxiety_psychic, anxiety_somatic, hypochondriasis; 0-2 three-point for insomnia_initial, insomnia_middle, insomnia_delayed, agitation, somatic_gastrointestinal, somatic_general, genital_symptoms, insight, loss_of_weight; max 50; no total-score severity bands

Citation

Title: A rating scale for depression
Authors: Hamilton M
Source: J Neurol Neurosurg Psychiatry. 1960;23(1):56-62
DOI: 10.1136/jnnp.23.1.56

Worked example

All items 0

Given: agitation=0anxiety_psychic=0anxiety_somatic=0depressed_mood=0genital_symptoms=0guilt=0hypochondriasis=0insight=0insomnia_delayed=0insomnia_initial=0insomnia_middle=0loss_of_weight=0retardation=0somatic_gastrointestinal=0somatic_general=0suicide=0work_and_interests=0

depressed_mood, guilt, suicide, insomnia_initial, insomnia_middle, insomnia_delayed, work_and_interests, retardation, agitation, anxiety_psychic, anxiety_somatic, somatic_gastrointestinal, somatic_general, genital_symptoms, hypochondriasis, insight, and loss_of_weight are 0 as assigned by the caller
Score = 0 (max 50). Hamilton 1960 published no total-score severity band.

All items at published maximum

Given: agitation=2anxiety_psychic=4anxiety_somatic=4depressed_mood=4genital_symptoms=2guilt=4hypochondriasis=4insight=2insomnia_delayed=2insomnia_initial=2insomnia_middle=2loss_of_weight=2retardation=4somatic_gastrointestinal=2somatic_general=2suicide=4work_and_interests=4

eight Hamilton 1960 five-point items are 4 and nine three-point items (including agitation) are 2 as assigned by the caller
Score = 50 (max 50). No total-score severity band.

Also searched as

HAM-D
HDRS
HRSD
Hamilton depression rating scale
Hamilton Rating Scale for Depression
HAM-D17
Hamilton 1960 depression
17-item Hamilton depression

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/hamilton_depression?depressed_mood=0&guilt=0&suicide=0&insomnia_initial=0&insomnia_middle=0&insomnia_delayed=0&work_and_interests=0&retardation=0&agitation=0&anxiety_psychic=0&anxiety_somatic=0&somatic_gastrointestinal=0&somatic_general=0&genital_symptoms=0&hypochondriasis=0&insight=0&loss_of_weight=0

Full URL: https://api.magentlab.com/api/calc/hamilton_depression?depressed_mood=0&guilt=0&suicide=0&insomnia_initial=0&insomnia_middle=0&insomnia_delayed=0&work_and_interests=0&retardation=0&agitation=0&anxiety_psychic=0&anxiety_somatic=0&somatic_gastrointestinal=0&somatic_general=0&genital_symptoms=0&hypochondriasis=0&insight=0&loss_of_weight=0

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/hamilton_depression?depressed_mood=0&guilt=0&suicide=0&insomnia_initial=0&insomnia_middle=0&insomnia_delayed=0&work_and_interests=0&retardation=0&agitation=0&anxiety_psychic=0&anxiety_somatic=0&somatic_gastrointestinal=0&somatic_general=0&genital_symptoms=0&hypochondriasis=0&insight=0&loss_of_weight=0"

Parameters

Name	Type	Required	Description
`depressed_mood`	integer	required	Caller-assigned Hamilton 1960 depressed mood (integer 0-4: 0 absent, 1 mild or trivial, 2 moderate, 3 severe, 4 extreme): gloomy attitude, pessimism about the future, feeling of sadness, tendency to weep. magent does not interview the patient.
`guilt`	integer	required	Caller-assigned Hamilton 1960 guilt (integer 0-4): self-reproach, ideas of guilt, present illness as punishment, delusions or hallucinations of guilt. magent does not interview the patient.
`suicide`	integer	required	Caller-assigned Hamilton 1960 suicide (integer 0-4): feels life is not worth living, wishes to be dead, suicidal ideas; an attempt at suicide scores 4 (3 if sudden against little suicidal tendency). magent does not interview the patient.
`insomnia_initial`	integer	required	Caller-assigned Hamilton 1960 insomnia, initial (integer 0-2: 0 absent, 1 slight or doubtful, 2 clearly present): difficulty in falling asleep. magent does not interview the patient.
`insomnia_middle`	integer	required	Caller-assigned Hamilton 1960 insomnia, middle (integer 0-2): restless and disturbed during the night, waking during the night. magent does not interview the patient.
`insomnia_delayed`	integer	required	Caller-assigned Hamilton 1960 insomnia, delayed (integer 0-2): waking in the early hours of the morning and unable to fall asleep again. magent does not interview the patient.
`work_and_interests`	integer	required	Caller-assigned Hamilton 1960 work and interests (integer 0-4): feelings of incapacity, listlessness, loss of interest in hobbies, decreased social activities or productivity; given up work solely because of present illness is 4. magent does not interview the patient.
`retardation`	integer	required	Caller-assigned Hamilton 1960 retardation (integer 0-4): slowness of thought, speech, and activity, apathy, stupor (1 slight at interview, 2 obvious, 3 interview difficult, 4 complete stupor). magent does not interview the patient.
`agitation`	integer	required	Caller-assigned Hamilton 1960 agitation (integer 0-2 three-point; a five-point scale was impracticable in that paper): restlessness associated with anxiety. magent does not interview the patient.
`anxiety_psychic`	integer	required	Caller-assigned Hamilton 1960 anxiety, psychic (integer 0-4): tension and irritability, worrying about minor matters, apprehensive attitude, fears. magent does not interview the patient.
`anxiety_somatic`	integer	required	Caller-assigned Hamilton 1960 anxiety, somatic (integer 0-4): gastrointestinal (wind, indigestion), cardiovascular (palpitations, headaches), respiratory, genito-urinary, and other somatic anxiety. magent does not interview the patient.
`somatic_gastrointestinal`	integer	required	Caller-assigned Hamilton 1960 somatic symptoms, gastrointestinal (integer 0-2): loss of appetite, heavy feelings in abdomen, constipation. magent does not interview the patient.
`somatic_general`	integer	required	Caller-assigned Hamilton 1960 somatic symptoms, general (integer 0-2): heaviness in limbs, back, or head; diffuse backache; loss of energy and fatiguability. magent does not interview the patient.
`genital_symptoms`	integer	required	Caller-assigned Hamilton 1960 genital symptoms (integer 0-2): loss of libido, menstrual disturbances. magent does not interview the patient.
`hypochondriasis`	integer	required	Caller-assigned Hamilton 1960 hypochondriasis (integer 0-4): self-absorption (bodily), preoccupation with health, querulous attitude, hypochondriacal delusions. magent does not interview the patient.
`insight`	integer	required	Caller-assigned Hamilton 1960 insight (integer 0-2: 0 no loss, 1 partial or doubtful loss, 2 loss of insight), interpreted in terms of the patient's understanding and background. magent does not interview the patient.
`loss_of_weight`	integer	required	Caller-assigned Hamilton 1960 loss of weight (integer 0-2 three-point scale as published, because few patients know their normal weight). magent does not weigh the patient.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/hamilton_depression Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "agitation": "0",
      "anxiety_psychic": "0",
      "anxiety_somatic": "0",
      "depressed_mood": "0",
      "genital_symptoms": "0",
      "guilt": "0",
      "hypochondriasis": "0",
      "insight": "0",
      "insomnia_delayed": "0",
      "insomnia_initial": "0",
      "insomnia_middle": "0",
      "loss_of_weight": "0",
      "retardation": "0",
      "somatic_gastrointestinal": "0",
      "somatic_general": "0",
      "suicide": "0",
      "work_and_interests": "0"
    },
    {
      "agitation": "0",
      "anxiety_psychic": "0",
      "anxiety_somatic": "0",
      "depressed_mood": "0",
      "genital_symptoms": "0",
      "guilt": "0",
      "hypochondriasis": "0",
      "insight": "0",
      "insomnia_delayed": "0",
      "insomnia_initial": "0",
      "insomnia_middle": "0",
      "loss_of_weight": "0",
      "retardation": "0",
      "somatic_gastrointestinal": "0",
      "somatic_general": "0",
      "suicide": "0",
      "work_and_interests": "0"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/hamilton_depression",
  "items": [
    {
      "components": [
        {
          "value": 0,
          "factor": "depressed_mood",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "guilt",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "suicide",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "insomnia_initial",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "insomnia_middle",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "insomnia_delayed",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "work_and_interests",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "retardation",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "agitation",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "anxiety_psychic",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "anxiety_somatic",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "somatic_gastrointestinal",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "somatic_general",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "genital_symptoms",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "hypochondriasis",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "insight",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "loss_of_weight",
          "points": 0,
          "present": true
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Hamilton M",
        "doi": "10.1136/jnnp.23.1.56",
        "id": "hamilton-1960",
        "pmid": "14399272",
        "source": "J Neurol Neurosurg Psychiatry. 1960;23(1):56-62",
        "title": "A rating scale for depression"
      },
      "formula": "hamilton_depression",
      "formula_expression": "HAM-D = depressed_mood + guilt + suicide + insomnia_initial + insomnia_middle + insomnia_delayed + work_and_interests + retardation + agitation + anxiety_psychic + anxiety_somatic + somatic_gastrointestinal + somatic_general + genital_symptoms + hypochondriasis + insight + loss_of_weight; Hamilton 1960 17 variables (not items 18-21); 0-4 five-point for depressed_mood, guilt, suicide, work_and_interests, retardation, anxiety_psychic, anxiety_somatic, hypochondriasis; 0-2 three-point for insomnia_initial, insomnia_middle, insomnia_delayed, agitation, somatic_gastrointestinal, somatic_general, genital_symptoms, insight, loss_of_weight; max 50; no total-score severity bands",
      "max_score": 50,
      "score": 0
    },
    {
      "components": [
        {
          "value": 0,
          "factor": "depressed_mood",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "guilt",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "suicide",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "insomnia_initial",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "insomnia_middle",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "insomnia_delayed",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "work_and_interests",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "retardation",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "agitation",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "anxiety_psychic",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "anxiety_somatic",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "somatic_gastrointestinal",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "somatic_general",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "genital_symptoms",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "hypochondriasis",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "insight",
          "points": 0,
          "present": true
        },
        {
          "value": 0,
          "factor": "loss_of_weight",
          "points": 0,
          "present": true
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Hamilton M",
        "doi": "10.1136/jnnp.23.1.56",
        "id": "hamilton-1960",
        "pmid": "14399272",
        "source": "J Neurol Neurosurg Psychiatry. 1960;23(1):56-62",
        "title": "A rating scale for depression"
      },
      "formula": "hamilton_depression",
      "formula_expression": "HAM-D = depressed_mood + guilt + suicide + insomnia_initial + insomnia_middle + insomnia_delayed + work_and_interests + retardation + agitation + anxiety_psychic + anxiety_somatic + somatic_gastrointestinal + somatic_general + genital_symptoms + hypochondriasis + insight + loss_of_weight; Hamilton 1960 17 variables (not items 18-21); 0-4 five-point for depressed_mood, guilt, suicide, work_and_interests, retardation, anxiety_psychic, anxiety_somatic, hypochondriasis; 0-2 three-point for insomnia_initial, insomnia_middle, insomnia_delayed, agitation, somatic_gastrointestinal, somatic_general, genital_symptoms, insight, loss_of_weight; max 50; no total-score severity bands",
      "max_score": 50,
      "score": 0
    }
  ]
}

Response

Field	Type	Description
`formula`	string	hamilton_depression
`formula_expression`	string	Exact expression used
`score`	integer	Hamilton 1960 sum of 17 caller-assigned items (eight 0-4 and nine 0-2; total 0-50)
`max_score`	integer	Always 50
`components`	array	Per-item caller-assigned points
`citation`	object	Hamilton J Neurol Neurosurg Psychiatry 1960 citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "components": [
    {
      "value": 0,
      "factor": "depressed_mood",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "guilt",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "suicide",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "insomnia_initial",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "insomnia_middle",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "insomnia_delayed",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "work_and_interests",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "retardation",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "agitation",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "anxiety_psychic",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "anxiety_somatic",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "somatic_gastrointestinal",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "somatic_general",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "genital_symptoms",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "hypochondriasis",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "insight",
      "points": 0,
      "present": true
    },
    {
      "value": 0,
      "factor": "loss_of_weight",
      "points": 0,
      "present": true
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Hamilton M",
    "doi": "10.1136/jnnp.23.1.56",
    "id": "hamilton-1960",
    "pmid": "14399272",
    "source": "J Neurol Neurosurg Psychiatry. 1960;23(1):56-62",
    "title": "A rating scale for depression"
  },
  "formula": "hamilton_depression",
  "formula_expression": "HAM-D = depressed_mood + guilt + suicide + insomnia_initial + insomnia_middle + insomnia_delayed + work_and_interests + retardation + agitation + anxiety_psychic + anxiety_somatic + somatic_gastrointestinal + somatic_general + genital_symptoms + hypochondriasis + insight + loss_of_weight; Hamilton 1960 17 variables (not items 18-21); 0-4 five-point for depressed_mood, guilt, suicide, work_and_interests, retardation, anxiety_psychic, anxiety_somatic, hypochondriasis; 0-2 three-point for insomnia_initial, insomnia_middle, insomnia_delayed, agitation, somatic_gastrointestinal, somatic_general, genital_symptoms, insight, loss_of_weight; max 50; no total-score severity bands",
  "max_score": 50,
  "score": 0
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_hamilton_depression`	Hamilton depression rating items must be integers in the Hamilton 1960 published ranges for those 17 variables. Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

PHQ-9 — Sum nine caller-assigned Kroenke 2001 PHQ-9 integers (0-3) and return the published total (max 27), severity cutpoints, and ≥10 screen.
QIDS — Map 16 caller-assigned Rush 2003 QIDS-SR integers (0-3) to nine DSM-IV domains (sleep, appetite/weight, and psychomotor are each the published max of their items) and return the 0-27 total and IRT severity band.
MDI — Map 12 caller-assigned Bech 2001 MDI integers (0-5 over the last 2 weeks) to ten DSM-IV/ICD-10 symptom items (appetite and psychomotor are each the published max of their pair) and return the 0-50 total and whether it meets this paper's optimal cutoff of 26.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.