Liver · LIVE

Lille score (Louvet 2007)

Lille score

Compute the Louvet 2007 Lille score from age, day-0 albumin, bilirubin on day 0 and day 7, creatinine, and PT seconds or INR. formula is required.

LIVE $0.005 USDC GET /api/calc/lille

Markdown: /docs/lille.md · Canonical: https://magentlab.com/docs/lille

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Louvet 2007 Lille score from age, day-0 albumin, bilirubin on day 0 and day 7, creatinine, and PT seconds or INR. formula is required.

When to use

When an agent needs the published Lille logistic and 0.45 cutoff and must not swap PT for INR or treat the band as a steroid order.

When not to use

• Not a medical device. magent does not recommend starting, stopping, or continuing corticosteroids or any other therapy.
• formula=pt or formula=inr is required. PT seconds and INR are not interchangeable; magent does not convert one to the other.
• responder and nonresponder are the paper's 0.45 cutoff on the Lille score, not a steroid order.

Formula

R = 3.19 - 0.101*age + 0.147*albumin_g_l + 0.0165*evolution_bilirubin_umol_l - 0.206*renal_insufficiency - 0.0065*bilirubin_day0_umol_l - 0.0096*pt_sec; lille_score = exp(-R)/(1+exp(-R))

Citation

Title

The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids

Authors

Louvet A, Naveau S, Abdelnour M, et al.

Source

Hepatology. 2007;45(6):1348-1354

DOI

10.1002/hep.21607

Worked example

Also searched as

• Lille score
• Lille model
• Louvet Lille
• alcoholic hepatitis Lille
• Lille 0.45
• steroid response Lille
• Lille PT INR

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/lille?age=50&albumin_g_l=35&bilirubin_day0_umol_l=200&bilirubin_day7_umol_l=150&creatinine_mg_dl=1.0&formula=pt&pt_sec=18

Full URL: https://api.magentlab.com/api/calc/lille?age=50&albumin_g_l=35&bilirubin_day0_umol_l=200&bilirubin_day7_umol_l=150&creatinine_mg_dl=1.0&formula=pt&pt_sec=18

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/lille?age=50&albumin_g_l=35&bilirubin_day0_umol_l=200&bilirubin_day7_umol_l=150&creatinine_mg_dl=1.0&formula=pt&pt_sec=18"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/lille Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "50",
      "albumin_g_l": "35",
      "bilirubin_day0_umol_l": "200",
      "bilirubin_day7_umol_l": "150",
      "creatinine_mg_dl": "1.0",
      "formula": "pt",
      "pt_sec": "18"
    },
    {
      "age": "50",
      "albumin_g_l": "35",
      "bilirubin_day0_umol_l": "200",
      "bilirubin_day7_umol_l": "150",
      "creatinine_mg_dl": "1.0",
      "formula": "pt",
      "pt_sec": "18"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/lille",
  "items": [
    {
      "response": "responder",
      "r": 2.6372,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Louvet A, Naveau S, Abdelnour M, et al.",
        "doi": "10.1002/hep.21607",
        "id": "louvet-2007",
        "pmid": "17518367",
        "source": "Hepatology. 2007;45(6):1348-1354",
        "title": "The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids"
      },
      "formula": "pt",
      "formula_expression": "R = 3.19 - 0.101*age + 0.147*albumin_g_l + 0.0165*evolution_bilirubin_umol_l - 0.206*renal_insufficiency - 0.0065*bilirubin_day0_umol_l - 0.0096*pt_sec; lille_score = exp(-R)/(1+exp(-R))",
      "age_years": 50,
      "creatinine_mg_dl": 1.0,
      "albumin_g_l": 35.0,
      "pt_sec": 18.0,
      "bilirubin_day0_umol_l": 200.0,
      "bilirubin_day7_umol_l": 150.0,
      "evolution_bilirubin_umol_l": 50.0,
      "lille_score": 0.0668,
      "renal_insufficiency": false
    },
    {
      "response": "responder",
      "r": 2.6372,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Louvet A, Naveau S, Abdelnour M, et al.",
        "doi": "10.1002/hep.21607",
        "id": "louvet-2007",
        "pmid": "17518367",
        "source": "Hepatology. 2007;45(6):1348-1354",
        "title": "The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids"
      },
      "formula": "pt",
      "formula_expression": "R = 3.19 - 0.101*age + 0.147*albumin_g_l + 0.0165*evolution_bilirubin_umol_l - 0.206*renal_insufficiency - 0.0065*bilirubin_day0_umol_l - 0.0096*pt_sec; lille_score = exp(-R)/(1+exp(-R))",
      "age_years": 50,
      "creatinine_mg_dl": 1.0,
      "albumin_g_l": 35.0,
      "pt_sec": 18.0,
      "bilirubin_day0_umol_l": 200.0,
      "bilirubin_day7_umol_l": 150.0,
      "evolution_bilirubin_umol_l": 50.0,
      "lille_score": 0.0668,
      "renal_insufficiency": false
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "response": "responder",
  "r": 2.6372,
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Louvet A, Naveau S, Abdelnour M, et al.",
    "doi": "10.1002/hep.21607",
    "id": "louvet-2007",
    "pmid": "17518367",
    "source": "Hepatology. 2007;45(6):1348-1354",
    "title": "The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids"
  },
  "formula": "pt",
  "formula_expression": "R = 3.19 - 0.101*age + 0.147*albumin_g_l + 0.0165*evolution_bilirubin_umol_l - 0.206*renal_insufficiency - 0.0065*bilirubin_day0_umol_l - 0.0096*pt_sec; lille_score = exp(-R)/(1+exp(-R))",
  "age_years": 50,
  "creatinine_mg_dl": 1.0,
  "albumin_g_l": 35.0,
  "pt_sec": 18.0,
  "bilirubin_day0_umol_l": 200.0,
  "bilirubin_day7_umol_l": 150.0,
  "evolution_bilirubin_umol_l": 50.0,
  "lille_score": 0.0668,
  "renal_insufficiency": false
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• Maddrey DF — Compute the 1978 Maddrey discriminant function from patient PT, control PT, and bilirubin.
• GAHS — Compute the Forrest 2005 Glasgow alcoholic hepatitis score (5-12) and the published ≥9 band.
• MELD-Na — Compute OPTN/UNOS 2016 MELD and MELD-Na from creatinine, bilirubin, INR, sodium, and dialysis.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.