Mehran CIN risk score after PCI

Mehran CIN risk score

Sum the Mehran 2004 eGFR model B integer score for contrast-induced nephropathy after PCI and return low (≤5), moderate (6–10), high (11–15), or very_high (≥16) with the development-set CIN percent.

LIVE $0.005 USDC GET /api/calc/mehran

Markdown: /docs/mehran.md · Canonical: https://magentlab.com/docs/mehran

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

When to use

When an agent already has caller-assigned hypotension, IABP, CHF, anemia, diabetes, contrast volume, and eGFR and needs the published Mehran 2004 point total. magent does not measure contrast or compute eGFR. Not a CKD diagnosis.

When not to use

Not a medical device and not a CKD diagnosis or a diagnosis of contrast-induced nephropathy.
magent does not measure contrast. contrast_ml is a caller-supplied integer (10-1000).
egfr_ml_min is caller-assigned. magent does not compute eGFR and does not implement race-based MDRD.
This is Mehran 2004 Table 3 model B (eGFR bands) only. Serum creatinine >1.5 is the alternate model A and is not added; that would double-count.
Hypotension (SBP <80 mm Hg ≥1 h requiring inotropes or IABP within 24 h), IABP, CHF (NYHA III/IV and/or pulmonary edema), anemia (WHO hematocrit), and diabetes are caller-assigned flags. magent does not examine the patient or assay hematocrit.
Risk groups are ≤5 / 6–10 / 11–15 / ≥16. Score 16 is very_high. CIN percents are the development-set four-group rates (7.5 / 14.0 / 26.1 / 57.3). Dialysis and one-year mortality are separate figures and are not returned.

Formula

Mehran 2004 model B = hypotension(5) + iabp(5) + chf(5) + age>75(4) + anemia(3) + diabetes(3) + floor(contrast_ml/100) + eGFR (>=60: 0, 40 to <60: 2, 20 to <40: 4, <20: 6); max 41 with contrast_ml 10-1000; risk_group low <=5, moderate 6-10, high 11-15, very_high >=16; development CIN 7.5% / 14.0% / 26.1% / 57.3%

Citation

Title: A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation
Authors: Mehran R, Aymong ED, Nikolsky E, et al.
Source: J Am Coll Cardiol. 2004;44(7):1393-1399
DOI: 10.1016/j.jacc.2004.06.068

Worked example

Age 60, no flags, 100 mL contrast, eGFR 90

Given: age=60anemia=falsechf=falsecontrast_ml=100diabetes=falseegfr_ml_min=90hypotension=falseiabp=false

No hypotension, IABP, CHF, anemia, or diabetes → 0; age 60 is not >75 → 0
contrast_ml 100 → floor(100/100) = 1; eGFR 90 ≥60 → 0
Score = 1 (max 41); risk_group = low; development CIN 7.5%

Also searched as

Mehran score
Mehran CIN score
contrast-induced nephropathy risk
Mehran 2004
CIN risk score PCI
contrast nephropathy score
Mehran eGFR model

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/mehran?age=60&hypotension=false&iabp=false&chf=false&anemia=false&diabetes=false&contrast_ml=100&egfr_ml_min=90

Full URL: https://api.magentlab.com/api/calc/mehran?age=60&hypotension=false&iabp=false&chf=false&anemia=false&diabetes=false&contrast_ml=100&egfr_ml_min=90

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/mehran?age=60&hypotension=false&iabp=false&chf=false&anemia=false&diabetes=false&contrast_ml=100&egfr_ml_min=90"

Parameters

Name	Type	Required	Description
`age`	integer	required	Age in years (18-120). Age >75 scores 4 (Mehran 2004 Table 3 model B). Age 75 scores 0.
`hypotension`	boolean	required	Hypotension as assigned by the caller: SBP <80 mm Hg for ≥1 h requiring inotropes or IABP within 24 h (Mehran 2004). true scores 5. true or false. magent does not measure blood pressure.
`iabp`	boolean	required	Intra-aortic balloon pump use as assigned by the caller (Mehran 2004 Table 3). true scores 5. Independent of the hypotension flag. true or false.
`chf`	boolean	required	CHF as assigned by the caller: NYHA III/IV and/or pulmonary edema (Mehran 2004). true scores 5. true or false. magent does not examine the patient.
`anemia`	boolean	required	Anemia as assigned by the caller using WHO hematocrit <39% (men) or <36% (women) (Mehran 2004). true scores 3. Flag only; do not send a hematocrit number. magent does not assay hematocrit.
`diabetes`	boolean	required	Diabetes mellitus as assigned by the caller (Mehran 2004 Table 3). true scores 3. true or false.
`contrast_ml`	integer	required	Contrast volume in mL (integer 10-1000). Scores 1 per 100 mL: floor(contrast_ml/100) (Mehran 2004). 100 scores 1; 199 scores 1; 200 scores 2. magent does not measure contrast.
`egfr_ml_min`	number	required	Caller-assigned eGFR in mL/min/1.73m² (5-150). Mehran 2004 Table 3 model B: ≥60 scores 0; 40 to <60 scores 2; 20 to <40 scores 4; <20 scores 6. magent does not compute eGFR and does not use race-based MDRD. Do not send serum creatinine; creatinine >1.5 is the alternate model A and would double-count.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/mehran Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "60",
      "anemia": "false",
      "chf": "false",
      "contrast_ml": "100",
      "diabetes": "false",
      "egfr_ml_min": "90",
      "hypotension": "false",
      "iabp": "false"
    },
    {
      "age": "60",
      "anemia": "false",
      "chf": "false",
      "contrast_ml": "100",
      "diabetes": "false",
      "egfr_ml_min": "90",
      "hypotension": "false",
      "iabp": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/mehran",
  "items": [
    {
      "components": [
        {
          "factor": "hypotension",
          "points": 0,
          "present": false
        },
        {
          "factor": "iabp",
          "points": 0,
          "present": false
        },
        {
          "factor": "chf",
          "points": 0,
          "present": false
        },
        {
          "value": 60,
          "factor": "age_gt_75",
          "points": 0,
          "present": false
        },
        {
          "factor": "anemia",
          "points": 0,
          "present": false
        },
        {
          "factor": "diabetes",
          "points": 0,
          "present": false
        },
        {
          "value": 100,
          "factor": "contrast_ml",
          "points": 1,
          "present": true
        },
        {
          "value": 90.0,
          "factor": "egfr_ml_min",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Mehran R, Aymong ED, Nikolsky E, et al.",
        "doi": "10.1016/j.jacc.2004.06.068",
        "id": "mehran-2004",
        "pmid": "15464318",
        "source": "J Am Coll Cardiol. 2004;44(7):1393-1399",
        "title": "A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation"
      },
      "formula": "mehran",
      "formula_expression": "Mehran 2004 model B = hypotension(5) + iabp(5) + chf(5) + age>75(4) + anemia(3) + diabetes(3) + floor(contrast_ml/100) + eGFR (>=60: 0, 40 to <60: 2, 20 to <40: 4, <20: 6); max 41 with contrast_ml 10-1000; risk_group low <=5, moderate 6-10, high 11-15, very_high >=16; development CIN 7.5% / 14.0% / 26.1% / 57.3%",
      "age_years": 60,
      "max_score": 41,
      "score": 1,
      "anemia": false,
      "diabetes": false,
      "risk_group": "low",
      "chf": false,
      "cin_percent": 7.5,
      "contrast_ml": 100,
      "egfr_ml_min": 90.0,
      "hypotension": false,
      "iabp": false
    },
    {
      "components": [
        {
          "factor": "hypotension",
          "points": 0,
          "present": false
        },
        {
          "factor": "iabp",
          "points": 0,
          "present": false
        },
        {
          "factor": "chf",
          "points": 0,
          "present": false
        },
        {
          "value": 60,
          "factor": "age_gt_75",
          "points": 0,
          "present": false
        },
        {
          "factor": "anemia",
          "points": 0,
          "present": false
        },
        {
          "factor": "diabetes",
          "points": 0,
          "present": false
        },
        {
          "value": 100,
          "factor": "contrast_ml",
          "points": 1,
          "present": true
        },
        {
          "value": 90.0,
          "factor": "egfr_ml_min",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Mehran R, Aymong ED, Nikolsky E, et al.",
        "doi": "10.1016/j.jacc.2004.06.068",
        "id": "mehran-2004",
        "pmid": "15464318",
        "source": "J Am Coll Cardiol. 2004;44(7):1393-1399",
        "title": "A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation"
      },
      "formula": "mehran",
      "formula_expression": "Mehran 2004 model B = hypotension(5) + iabp(5) + chf(5) + age>75(4) + anemia(3) + diabetes(3) + floor(contrast_ml/100) + eGFR (>=60: 0, 40 to <60: 2, 20 to <40: 4, <20: 6); max 41 with contrast_ml 10-1000; risk_group low <=5, moderate 6-10, high 11-15, very_high >=16; development CIN 7.5% / 14.0% / 26.1% / 57.3%",
      "age_years": 60,
      "max_score": 41,
      "score": 1,
      "anemia": false,
      "diabetes": false,
      "risk_group": "low",
      "chf": false,
      "cin_percent": 7.5,
      "contrast_ml": 100,
      "egfr_ml_min": 90.0,
      "hypotension": false,
      "iabp": false
    }
  ]
}

Response

Field	Type	Description
`formula`	string	mehran
`formula_expression`	string	Mehran 2004 Table 3 eGFR model B integer score
`score`	integer	Mehran points (max 41 with contrast_ml 10-1000)
`max_score`	integer	Always 41 (5+5+5+4+3+3+10+6) with the magent contrast_ml clamp
`risk_group`	string	low (≤5), moderate (6-10), high (11-15), or very_high (≥16). Mehran 2004 development-set four groups. Score 16 is very_high, not high. Not a CKD or CIN diagnosis.
`cin_percent`	number	Development-set CIN percent for the risk group: 7.5, 14.0, 26.1, or 57.3 (Mehran 2004). Not a dialysis or mortality percent.
`age_years`	integer	Age used for the >75 criterion
`hypotension`	boolean	Caller-assigned hypotension flag used
`iabp`	boolean	Caller-assigned IABP flag used
`chf`	boolean	Caller-assigned CHF (NYHA III/IV and/or pulmonary edema) flag used
`anemia`	boolean	Caller-assigned WHO anemia flag used
`diabetes`	boolean	Caller-assigned diabetes flag used
`contrast_ml`	integer	Contrast volume in mL used for floor(contrast_ml/100)
`egfr_ml_min`	number	Caller-assigned eGFR in mL/min/1.73m² used for the model B band
`components`	array	Per-factor Mehran 2004 points
`citation`	object	Mehran 2004 JACC citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "components": [
    {
      "factor": "hypotension",
      "points": 0,
      "present": false
    },
    {
      "factor": "iabp",
      "points": 0,
      "present": false
    },
    {
      "factor": "chf",
      "points": 0,
      "present": false
    },
    {
      "value": 60,
      "factor": "age_gt_75",
      "points": 0,
      "present": false
    },
    {
      "factor": "anemia",
      "points": 0,
      "present": false
    },
    {
      "factor": "diabetes",
      "points": 0,
      "present": false
    },
    {
      "value": 100,
      "factor": "contrast_ml",
      "points": 1,
      "present": true
    },
    {
      "value": 90.0,
      "factor": "egfr_ml_min",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Mehran R, Aymong ED, Nikolsky E, et al.",
    "doi": "10.1016/j.jacc.2004.06.068",
    "id": "mehran-2004",
    "pmid": "15464318",
    "source": "J Am Coll Cardiol. 2004;44(7):1393-1399",
    "title": "A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation"
  },
  "formula": "mehran",
  "formula_expression": "Mehran 2004 model B = hypotension(5) + iabp(5) + chf(5) + age>75(4) + anemia(3) + diabetes(3) + floor(contrast_ml/100) + eGFR (>=60: 0, 40 to <60: 2, 20 to <40: 4, <20: 6); max 41 with contrast_ml 10-1000; risk_group low <=5, moderate 6-10, high 11-15, very_high >=16; development CIN 7.5% / 14.0% / 26.1% / 57.3%",
  "age_years": 60,
  "max_score": 41,
  "score": 1,
  "anemia": false,
  "diabetes": false,
  "risk_group": "low",
  "chf": false,
  "cin_percent": 7.5,
  "contrast_ml": 100,
  "egfr_ml_min": 90.0,
  "hypotension": false,
  "iabp": false
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_mehran`	contrast_ml 10-1000 and egfr_ml_min 5-150 (Mehran 2004; magent clamps). Returned before settlement; you are not charged.
400	`invalid_age`	age must be an integer from 18 to 120 Returned before settlement; you are not charged.
400	`invalid_flag`	boolean clinical flags must be true or false Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

AKIN — Apply Mehta 2007 Table 2 AKIN staging and return stage 0-3 as the worse of the creatinine and urine-output limbs, with initiated renal replacement therapy mapping to stage 3.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.