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Morphine milligram equivalents (CDC 2022)

Morphine milligram equivalents

Compute morphine milligram equivalents from a CDC 2022 table opioid and daily dose (or transdermal fentanyl mcg/hr).

Also searched as

• MME calculator
• morphine milligram equivalent
• morphine equivalent dose
• CDC opioid MME
• hydrocodone MME
• oxycodone MME
• fentanyl patch MME
• methadone MME factor

LIVE $0.005 USDC GET /api/calc/mme

Markdown: /docs/mme.md · Canonical: https://magentlab.com/docs/mme

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute morphine milligram equivalents from a CDC 2022 table opioid and daily dose (or transdermal fentanyl mcg/hr).

When to use

When an agent needs published CDC 2022 MME arithmetic and must not invent conversion factors or convert one opioid to another.

When not to use

• All doses are mg/day except fentanyl_transdermal, which is mcg/hr.
• MME values are estimates only and do not account for individual variability.
• Do not use MME to convert one opioid to another or to choose a replacement dose.
• The methadone conversion factor is an estimate; it increases at higher methadone doses.
• Transdermal fentanyl absorption can increase with fever or heat.
• Buprenorphine is not in the CDC 2022 table and is rejected.
• Not for opioid use disorder (OUD) dosing of methadone or buprenorphine.
• Analytic MME only; not a taper protocol, diagnosis, or dosing recommendation.

Formula

mme = dose * conversion_factor (dose is mg/day except fentanyl_transdermal in mcg/hr)

Citation

Title

CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022

Authors

Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R

Source

MMWR Recomm Rep. 2022;71(No. RR-3):1-95

DOI

10.15585/mmwr.rr7103a1

Worked example

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/mme?opioid=hydrocodone&dose=20

Full URL: https://api.magentlab.com/api/calc/mme?opioid=hydrocodone&dose=20

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/mme?opioid=hydrocodone&dose=20"

Parameters

Bulk (POST)

POST the same path with a JSON items array. Price is n times the GET unit. Invalid items return HTTP 400 before settlement.

POST /api/calc/mme Max 25 unit_amount * n PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "dose": "20",
      "opioid": "hydrocodone"
    },
    {
      "dose": "20",
      "opioid": "hydrocodone"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/mme",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R",
        "doi": "10.15585/mmwr.rr7103a1",
        "id": "cdc-mme-2022",
        "source": "MMWR Recomm Rep. 2022;71(No. RR-3):1-95",
        "title": "CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022"
      },
      "formula": "mme",
      "formula_expression": "mme = dose * conversion_factor (dose is mg/day except fentanyl_transdermal in mcg/hr)",
      "conversion_factor": 1.0,
      "dose": 20.0,
      "dose_unit": "mg/day",
      "mme": 20.0,
      "opioid": "hydrocodone"
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R",
        "doi": "10.15585/mmwr.rr7103a1",
        "id": "cdc-mme-2022",
        "source": "MMWR Recomm Rep. 2022;71(No. RR-3):1-95",
        "title": "CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022"
      },
      "formula": "mme",
      "formula_expression": "mme = dose * conversion_factor (dose is mg/day except fentanyl_transdermal in mcg/hr)",
      "conversion_factor": 1.0,
      "dose": 20.0,
      "dose_unit": "mg/day",
      "mme": 20.0,
      "opioid": "hydrocodone"
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R",
    "doi": "10.15585/mmwr.rr7103a1",
    "id": "cdc-mme-2022",
    "source": "MMWR Recomm Rep. 2022;71(No. RR-3):1-95",
    "title": "CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022"
  },
  "formula": "mme",
  "formula_expression": "mme = dose * conversion_factor (dose is mg/day except fentanyl_transdermal in mcg/hr)",
  "conversion_factor": 1.0,
  "dose": 20.0,
  "dose_unit": "mg/day",
  "mme": 20.0,
  "opioid": "hydrocodone"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• Glucocorticoid dose conversion — Convert a glucocorticoid dose among hydrocortisone, prednisone, and dexamethasone using Meikle 1977 equivalent doses (20 mg : 5 mg : 0.75 mg).

Payment

Required query parameters must be present and valid. Invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• Invalid query parameters return HTTP 400 before settlement. You are not charged.
• Settlement finishes before the tool executes (paymentFlow upfront). Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.