MAGENT

Infection / VTE · LIVE

Pediatric SIRS

Apply Goldstein 2005 pediatric SIRS age-group heart-rate, respiratory-rate, leukocyte, and core-temperature criteria, then the paper's sepsis, severe-sepsis, and septic-shock definitions from caller-assigned infection and organ-dysfunction flags.

LIVE $0.005 USDC GET /api/calc/pediatric_sirs

Markdown: /docs/pediatric-sirs.md · Canonical: https://magentlab.com/docs/pediatric-sirs

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply Goldstein 2005 pediatric SIRS age-group heart-rate, respiratory-rate, leukocyte, and core-temperature criteria, then the paper's sepsis, severe-sepsis, and septic-shock definitions from caller-assigned infection and organ-dysfunction flags.

When to use

When an agent already has a Goldstein 2005 age group, core temperature, heart rate, respiratory rate, and WBC and needs the published pediatric SIRS result, with optional sepsis, severe sepsis, and septic shock from caller-assigned flags. magent does not measure vitals or assay WBC. Not Bone 1992 adult SIRS. Not Phoenix 2024.

When not to use

  • Not a medical device.
  • Not a diagnosis of SIRS, sepsis, severe sepsis, or septic shock and not a sepsis workup, antibiotic, or vasopressor order.
  • magent does not measure vitals or assay WBC. The caller supplies age group, core temperature, heart rate, respiratory rate, and leukocyte count. Organ dysfunction is caller-assigned; magent does not apply Goldstein 2005 Table 4 from raw labs.
  • This tool is Goldstein 2005 pediatric SIRS (IPSCC) only. It is not Bone 1992 adult SIRS (temperature >38 °C, HR >90, RR >20, WBC >12000 or <4000/µL). It is not Phoenix 2024 / Schlapbach pediatric sepsis.
  • Age groups are the six published groups (newborn 0 days-1 week, neonate 1 week-1 month, infant 1 month-1 year, toddler/preschool 2-5 years, school-age 6-12 years, adolescent 13-18 years). magent does not map chronological age; the 1-2 year gap is in the paper. Newborn leukocyte has a high cutoff only (no published leukopenia bound). Bradycardia applies only under 1 year.
  • Pediatric SIRS requires at least two of four criteria, one of which must be abnormal core temperature (>38.5 or <36 °C) or leukocyte count. Heart rate plus respiratory rate alone is not SIRS. 38.5 °C and each Table 3 cutoff equality do not meet.

Formula

pediatric SIRS iff >=2 of 4 Goldstein 2005 Table 3 age-group criteria and (temperature or leukocyte): core temperature_c >38.5 or <36; heart_rate_bpm > tachycardia cutoff or (newborn/neonate/infant) < bradycardia cutoff; respiratory_rate > cutoff or mechanical_ventilation; wbc_k_ul > high or < low for age (newborn high-only) or band_percent >10; sepsis iff SIRS and suspected_infection; severe_sepsis iff sepsis and (cardiovascular_dysfunction or ards or two_or_more_other_organ_dysfunctions); septic_shock iff sepsis and cardiovascular_dysfunction

Citation

Title
International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics
Authors
Goldstein B, Giroir B, Randolph A; International Consensus Conference on Pediatric Sepsis
Source
Pediatr Crit Care Med. 2005;6(1):2-8
DOI
10.1097/01.PCC.0000149131.72248.E6

Worked example

Goldstein 2005 SIRS-negative school-age vitals

Given: age_group=school_ageards=falsecardiovascular_dysfunction=falseheart_rate_bpm=100respiratory_rate=16suspected_infection=falsetemperature_c=37.0two_or_more_other_organ_dysfunctions=falsewbc_k_ul=8.0

  1. age_group school_age uses Table 3 cutoffs HR >130, RR >18, WBC >13.5 or <4.5 k/µL
  2. Core temperature 37.0 is not >38.5 or <36
  3. HR 100 is not >130; RR 16 is not >18; WBC 8.0 k/µL is not >13.5 or <4.5
  4. 0 of 4 criteria; sirs_present is false (need ≥2 including temperature or leukocyte)

Also searched as

  • Pediatric SIRS
  • Goldstein 2005 pediatric sepsis
  • International pediatric sepsis consensus
  • Pediatric septic shock criteria
  • Age-specific SIRS
  • Pediatric severe sepsis
  • IPSCC 2005
  • Pediatric SIRS criteria

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/pediatric_sirs?age_group=school_age&temperature_c=37.0&heart_rate_bpm=100&respiratory_rate=16&wbc_k_ul=8.0&suspected_infection=false&cardiovascular_dysfunction=false&ards=false&two_or_more_other_organ_dysfunctions=false

Full URL: https://api.magentlab.com/api/calc/pediatric_sirs?age_group=school_age&temperature_c=37.0&heart_rate_bpm=100&respiratory_rate=16&wbc_k_ul=8.0&suspected_infection=false&cardiovascular_dysfunction=false&ards=false&two_or_more_other_organ_dysfunctions=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/pediatric_sirs?age_group=school_age&temperature_c=37.0&heart_rate_bpm=100&respiratory_rate=16&wbc_k_ul=8.0&suspected_infection=false&cardiovascular_dysfunction=false&ards=false&two_or_more_other_organ_dysfunctions=false"

Parameters

Name Type Required Description
age_group string required Goldstein 2005 Table 1 age group. One of: newborn (0 days to 1 week; HR >180 or <100, RR >50, WBC >34 k/µL), neonate (1 week to 1 month; HR >180 or <100, RR >40, WBC >19.5 or <5), infant (1 month to 1 year; HR >180 or <90, RR >34, WBC >17.5 or <5), toddler_preschool (2-5 years; HR >140, RR >22, WBC >15.5 or <6), school_age (6-12 years; HR >130, RR >18, WBC >13.5 or <4.5), adolescent (13-18 years; HR >110, RR >14, WBC >11 or <4.5). magent does not map chronological age (the paper has a 1-2 year gap).
temperature_c number required Core temperature in °C (30.0-45.0), rectal, bladder, oral, or central-catheter probe as in Goldstein 2005. >38.5 or <36 meets the temperature criterion (38.5 and 36.0 do not). Not Bone 1992 adult >38. magent does not measure temperature.
heart_rate_bpm integer required Heart rate in beats/min (integer 30-300). Meets when greater than the age-group tachycardia cutoff, or when less than the bradycardia cutoff for newborn, neonate, or infant only (Goldstein 2005 Table 3). Equal to the cutoff does not meet. magent does not measure heart rate.
respiratory_rate integer required Respiratory rate in breaths/min (integer 4-120). Meets when greater than the age-group cutoff (Goldstein 2005 Table 3). Equal to the cutoff does not meet. Optional mechanical_ventilation also meets this criterion. magent does not measure respiratory rate.
wbc_k_ul number optional WBC in 10^3/µL (same as 10^3/mm^3 in Goldstein 2005 Table 3). Provide wbc_k_ul or wbc_ul. Range 0.01-500. Meets when greater than the age-group high cutoff or less than the low cutoff (newborn has high-only; no leukopenia bound). Equal to a cutoff does not meet. magent does not assay WBC.
wbc_ul number optional WBC in cells/µL. Provide wbc_k_ul or wbc_ul. Range 10-500000. Converted to 10^3/µL for Table 3 cutoffs. magent does not assay WBC.
band_percent number optional Immature neutrophils as a percent of WBC (0-100) when provided. Omitted does not use bands. >10 meets the leukocyte criterion (10 does not). magent does not assay bands.
mechanical_ventilation boolean optional Caller-assigned mechanical ventilation for an acute process not related to underlying neuromuscular disease or general anesthesia (Goldstein 2005 Table 2 respiratory criterion). true meets the respiratory criterion. Omitted is false. true or false. magent does not examine ventilation.
suspected_infection boolean required Caller-assigned suspected or proven infection (Goldstein 2005 Table 2). Sepsis requires SIRS and this true. true or false. magent does not diagnose infection.
cardiovascular_dysfunction boolean required Caller-assigned cardiovascular organ dysfunction as in Goldstein 2005 Table 4. With SIRS and suspected_infection, this is septic shock (and severe sepsis). true or false. magent does not apply Table 4 from raw labs or blood pressure.
ards boolean required Caller-assigned acute respiratory distress syndrome as used for severe sepsis in Goldstein 2005 Table 2. true or false. magent does not interpret imaging or PaO2/FiO2.
two_or_more_other_organ_dysfunctions boolean required Caller-assigned two or more other organ dysfunctions (respiratory, renal, neurologic, hematologic, or hepatic per Goldstein 2005 Table 2/4) for severe sepsis when cardiovascular dysfunction and ARDS are absent. true or false. magent does not apply Table 4 from raw labs.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/pediatric_sirs Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age_group": "school_age",
      "ards": "false",
      "cardiovascular_dysfunction": "false",
      "heart_rate_bpm": "100",
      "respiratory_rate": "16",
      "suspected_infection": "false",
      "temperature_c": "37.0",
      "two_or_more_other_organ_dysfunctions": "false",
      "wbc_k_ul": "8.0"
    },
    {
      "age_group": "school_age",
      "ards": "false",
      "cardiovascular_dysfunction": "false",
      "heart_rate_bpm": "100",
      "respiratory_rate": "16",
      "suspected_infection": "false",
      "temperature_c": "37.0",
      "two_or_more_other_organ_dysfunctions": "false",
      "wbc_k_ul": "8.0"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/pediatric_sirs",
  "items": [
    {
      "category": "none",
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Goldstein B, Giroir B, Randolph A; International Consensus Conference on Pediatric Sepsis",
        "doi": "10.1097/01.PCC.0000149131.72248.E6",
        "id": "goldstein-2005",
        "pmid": "15636651",
        "source": "Pediatr Crit Care Med. 2005;6(1):2-8",
        "title": "International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics"
      },
      "formula": "pediatric_sirs",
      "formula_expression": "pediatric SIRS iff >=2 of 4 Goldstein 2005 Table 3 age-group criteria and (temperature or leukocyte): core temperature_c >38.5 or <36; heart_rate_bpm > tachycardia cutoff or (newborn/neonate/infant) < bradycardia cutoff; respiratory_rate > cutoff or mechanical_ventilation; wbc_k_ul > high or < low for age (newborn high-only) or band_percent >10; sepsis iff SIRS and suspected_infection; severe_sepsis iff sepsis and (cardiovascular_dysfunction or ards or two_or_more_other_organ_dysfunctions); septic_shock iff sepsis and cardiovascular_dysfunction",
      "criteria": [
        {
          "value": 37.0,
          "factor": "temperature",
          "met": false
        },
        {
          "value": 100,
          "factor": "heart_rate",
          "met": false
        },
        {
          "value": 16,
          "factor": "respiratory",
          "met": false
        },
        {
          "value": 8.0,
          "factor": "leukocyte",
          "met": false
        },
        {
          "factor": "suspected_infection",
          "met": false
        },
        {
          "factor": "cardiovascular_dysfunction",
          "met": false
        },
        {
          "factor": "ards",
          "met": false
        },
        {
          "factor": "two_or_more_other_organ_dysfunctions",
          "met": false
        }
      ],
      "heart_rate_bpm": 100,
      "temperature_c": 37.0,
      "respiratory_rate": 16,
      "wbc_k_ul": 8.0,
      "age_group": "school_age",
      "sepsis": false,
      "septic_shock": false,
      "severe_sepsis": false,
      "sirs_criteria_met": 0,
      "sirs_present": false
    },
    {
      "category": "none",
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Goldstein B, Giroir B, Randolph A; International Consensus Conference on Pediatric Sepsis",
        "doi": "10.1097/01.PCC.0000149131.72248.E6",
        "id": "goldstein-2005",
        "pmid": "15636651",
        "source": "Pediatr Crit Care Med. 2005;6(1):2-8",
        "title": "International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics"
      },
      "formula": "pediatric_sirs",
      "formula_expression": "pediatric SIRS iff >=2 of 4 Goldstein 2005 Table 3 age-group criteria and (temperature or leukocyte): core temperature_c >38.5 or <36; heart_rate_bpm > tachycardia cutoff or (newborn/neonate/infant) < bradycardia cutoff; respiratory_rate > cutoff or mechanical_ventilation; wbc_k_ul > high or < low for age (newborn high-only) or band_percent >10; sepsis iff SIRS and suspected_infection; severe_sepsis iff sepsis and (cardiovascular_dysfunction or ards or two_or_more_other_organ_dysfunctions); septic_shock iff sepsis and cardiovascular_dysfunction",
      "criteria": [
        {
          "value": 37.0,
          "factor": "temperature",
          "met": false
        },
        {
          "value": 100,
          "factor": "heart_rate",
          "met": false
        },
        {
          "value": 16,
          "factor": "respiratory",
          "met": false
        },
        {
          "value": 8.0,
          "factor": "leukocyte",
          "met": false
        },
        {
          "factor": "suspected_infection",
          "met": false
        },
        {
          "factor": "cardiovascular_dysfunction",
          "met": false
        },
        {
          "factor": "ards",
          "met": false
        },
        {
          "factor": "two_or_more_other_organ_dysfunctions",
          "met": false
        }
      ],
      "heart_rate_bpm": 100,
      "temperature_c": 37.0,
      "respiratory_rate": 16,
      "wbc_k_ul": 8.0,
      "age_group": "school_age",
      "sepsis": false,
      "septic_shock": false,
      "severe_sepsis": false,
      "sirs_criteria_met": 0,
      "sirs_present": false
    }
  ]
}

Response

Field Type Description
formula string pediatric_sirs
formula_expression string Goldstein 2005 pediatric SIRS, sepsis, severe sepsis, and septic shock
sirs_present boolean true when at least two of four Table 3 criteria are met and at least one is temperature or leukocyte. Heart rate plus respiratory rate alone is not SIRS. Not a diagnosis.
sirs_criteria_met integer Count of the four Goldstein 2005 Table 3 criteria that are met (0-4)
sepsis boolean true when sirs_present and suspected_infection (Goldstein 2005 Table 2). Not a diagnosis or antibiotic order.
severe_sepsis boolean true when sepsis and (cardiovascular_dysfunction or ards or two_or_more_other_organ_dysfunctions). Not a diagnosis.
septic_shock boolean true when sepsis and cardiovascular_dysfunction (Goldstein 2005 Table 2). Not a vasopressor order.
category string none, sirs, sepsis, severe_sepsis, or septic_shock. Highest published rung that holds. Not Phoenix 2024.
age_group string Goldstein 2005 Table 1 age group used for Table 3 cutoffs
temperature_c number Core temperature in °C used
heart_rate_bpm integer Heart rate used, bpm
respiratory_rate integer Respiratory rate used, breaths/min
wbc_k_ul number WBC in 10^3/µL used for Table 3 cutoffs
criteria array Per-criterion rows with factor and met: temperature, heart_rate, respiratory, leukocyte, suspected_infection, cardiovascular_dysfunction, ards, two_or_more_other_organ_dysfunctions
citation object Goldstein 2005 Pediatr Crit Care Med citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "category": "none",
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Goldstein B, Giroir B, Randolph A; International Consensus Conference on Pediatric Sepsis",
    "doi": "10.1097/01.PCC.0000149131.72248.E6",
    "id": "goldstein-2005",
    "pmid": "15636651",
    "source": "Pediatr Crit Care Med. 2005;6(1):2-8",
    "title": "International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics"
  },
  "formula": "pediatric_sirs",
  "formula_expression": "pediatric SIRS iff >=2 of 4 Goldstein 2005 Table 3 age-group criteria and (temperature or leukocyte): core temperature_c >38.5 or <36; heart_rate_bpm > tachycardia cutoff or (newborn/neonate/infant) < bradycardia cutoff; respiratory_rate > cutoff or mechanical_ventilation; wbc_k_ul > high or < low for age (newborn high-only) or band_percent >10; sepsis iff SIRS and suspected_infection; severe_sepsis iff sepsis and (cardiovascular_dysfunction or ards or two_or_more_other_organ_dysfunctions); septic_shock iff sepsis and cardiovascular_dysfunction",
  "criteria": [
    {
      "value": 37.0,
      "factor": "temperature",
      "met": false
    },
    {
      "value": 100,
      "factor": "heart_rate",
      "met": false
    },
    {
      "value": 16,
      "factor": "respiratory",
      "met": false
    },
    {
      "value": 8.0,
      "factor": "leukocyte",
      "met": false
    },
    {
      "factor": "suspected_infection",
      "met": false
    },
    {
      "factor": "cardiovascular_dysfunction",
      "met": false
    },
    {
      "factor": "ards",
      "met": false
    },
    {
      "factor": "two_or_more_other_organ_dysfunctions",
      "met": false
    }
  ],
  "heart_rate_bpm": 100,
  "temperature_c": 37.0,
  "respiratory_rate": 16,
  "wbc_k_ul": 8.0,
  "age_group": "school_age",
  "sepsis": false,
  "septic_shock": false,
  "severe_sepsis": false,
  "sirs_criteria_met": 0,
  "sirs_present": false
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_pediatric_sirs Pediatric SIRS inputs must match Goldstein 2005 age-group vital-sign and WBC thresholds from that paper only. Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • SIRS — Compute the Bone 1992 ACCP/SCCM SIRS criteria from temperature, heart rate, respiratory rate, and WBC, with optional PaCO2 and band percent.
  • Phoenix Sepsis Score — Sum four caller-assigned Schlapbach 2024 Phoenix Sepsis Score organ integers and return sepsis (suspected infection and score ≥2) and septic shock (sepsis with cardiovascular ≥1).
  • qSOFA — Compute the Sepsis-3 qSOFA score from respiratory rate, caller-assigned altered mentation, and systolic blood pressure.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.