MAGENT

Infection / VTE · LIVE

Altitude-adjusted PERC

Apply the Madsen 2019 altitude-adjusted eight-factor pulmonary embolism rule-out criteria (hypoxia as O2 sat <90% at ~4980 ft) and return whether all eight are met (PERC-negative).

LIVE $0.005 USDC GET /api/calc/perc_altitude

Markdown: /docs/perc-altitude.md · Canonical: https://magentlab.com/docs/perc-altitude

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Madsen 2019 altitude-adjusted eight-factor pulmonary embolism rule-out criteria (hypoxia as O2 sat <90% at ~4980 ft) and return whether all eight are met (PERC-negative).

When to use

When an agent already has a low pretest probability of PE, as in Kline, and the encounter is at altitude as studied by Madsen (chest pain and/or SOB at ~4980 ft), and needs a published altitude-adjusted PERC-negative result from caller-assigned findings.

When not to use

  • Not a medical device.
  • Not a PE diagnosis and not sea-level PERC (that is perc). Not a D-dimer protocol.
  • Only for patients who already have a low pretest probability of pulmonary embolism, as in Kline. Madsen studied chest pain and/or SOB at altitude. magent does not assign pretest probability.
  • The caller assigns age, pulse, SaO2, and the five clinical flags. magent does not measure vitals or examine the patient.

Formula

PERC-negative iff age < 50 and pulse < 100 bpm and SaO2 ≥ 90% and no unilateral leg swelling and no hemoptysis and no recent trauma or surgery and no prior PE or DVT and no hormone use

Citation

Title
Impact of altitude-adjusted hypoxia on the Pulmonary Embolism Rule-out Criteria.
Authors
Madsen T, Jedick R, Teeples T, Carlson M, Steenblik J
Source
Am J Emerg Med. 2019;37(2):281-285 (Epub 2018 May 24)
DOI
10.1016/j.ajem.2018.05.050

Worked example

All eight criteria met at SaO2 90

Given: age=40estrogen_use=falseheart_rate_bpm=80hemoptysis=falseprior_vte=falserecent_surgery_or_trauma=falsespo2_percent=90unilateral_leg_swelling=false

  1. Age 40 < 50; pulse 80 < 100; SaO2 90 ≥ 90 (meets altitude-adjusted hypoxia; would fail sea-level PERC >94)
  2. Five harmful findings absent
  3. PERC-negative

Age 50 fails the age criterion

Given: age=50estrogen_use=falseheart_rate_bpm=80hemoptysis=falseprior_vte=falserecent_surgery_or_trauma=falsespo2_percent=90unilateral_leg_swelling=false

  1. Age 50 is not < 50
  2. PERC-negative is false

Also searched as

  • altitude-adjusted PERC
  • Madsen PERC
  • PERC altitude
  • altitude PERC rule
  • hypoxia-adjusted PERC
  • PERC 4980 ft
  • altitude-adjusted pulmonary embolism rule-out

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/perc_altitude?age=40&heart_rate_bpm=80&spo2_percent=90&unilateral_leg_swelling=false&hemoptysis=false&recent_surgery_or_trauma=false&prior_vte=false&estrogen_use=false

Full URL: https://api.magentlab.com/api/calc/perc_altitude?age=40&heart_rate_bpm=80&spo2_percent=90&unilateral_leg_swelling=false&hemoptysis=false&recent_surgery_or_trauma=false&prior_vte=false&estrogen_use=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/perc_altitude?age=40&heart_rate_bpm=80&spo2_percent=90&unilateral_leg_swelling=false&hemoptysis=false&recent_surgery_or_trauma=false&prior_vte=false&estrogen_use=false"

Parameters

Name Type Required Description
age integer required Age in years (18-120). Criterion met when age < 50; 50 does not meet.
heart_rate_bpm integer required Pulse in beats per minute (integer 30-220). Criterion met when pulse < 100; 100 does not meet.
spo2_percent number required Oxygen saturation percent (50-100). Criterion met when SaO2 ≥ 90; 89.9 does not meet. Madsen 2019 altitude adjustment, not sea-level PERC >94.
unilateral_leg_swelling boolean required Unilateral leg swelling. true or false as assigned by the caller. Criterion met when false.
hemoptysis boolean required Hemoptysis. true or false as assigned by the caller. Criterion met when false.
recent_surgery_or_trauma boolean required Recent trauma or surgery. true or false as assigned by the caller. Criterion met when false.
prior_vte boolean required Prior PE or DVT. true or false as assigned by the caller. Criterion met when false.
estrogen_use boolean required Hormone or exogenous estrogen use. true or false as assigned by the caller. Criterion met when false.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/perc_altitude Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "40",
      "estrogen_use": "false",
      "heart_rate_bpm": "80",
      "hemoptysis": "false",
      "prior_vte": "false",
      "recent_surgery_or_trauma": "false",
      "spo2_percent": "90",
      "unilateral_leg_swelling": "false"
    },
    {
      "age": "40",
      "estrogen_use": "false",
      "heart_rate_bpm": "80",
      "hemoptysis": "false",
      "prior_vte": "false",
      "recent_surgery_or_trauma": "false",
      "spo2_percent": "90",
      "unilateral_leg_swelling": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/perc_altitude",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Madsen T, Jedick R, Teeples T, Carlson M, Steenblik J",
        "doi": "10.1016/j.ajem.2018.05.050",
        "id": "madsen-2019",
        "pmid": "29848460",
        "source": "Am J Emerg Med. 2019;37(2):281-285 (Epub 2018 May 24)",
        "title": "Impact of altitude-adjusted hypoxia on the Pulmonary Embolism Rule-out Criteria."
      },
      "formula": "perc_altitude",
      "formula_expression": "PERC-negative iff age < 50 and pulse < 100 bpm and SaO2 ≥ 90% and no unilateral leg swelling and no hemoptysis and no recent trauma or surgery and no prior PE or DVT and no hormone use",
      "criteria": [
        {
          "value": 40,
          "factor": "age_lt_50",
          "met": true
        },
        {
          "value": 80,
          "factor": "pulse_lt_100",
          "met": true
        },
        {
          "value": 90.0,
          "factor": "sao2_ge_90",
          "met": true
        },
        {
          "factor": "no_unilateral_leg_swelling",
          "met": true
        },
        {
          "factor": "no_hemoptysis",
          "met": true
        },
        {
          "factor": "no_recent_surgery_or_trauma",
          "met": true
        },
        {
          "factor": "no_prior_vte",
          "met": true
        },
        {
          "factor": "no_estrogen_use",
          "met": true
        }
      ],
      "perc_negative": true
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Madsen T, Jedick R, Teeples T, Carlson M, Steenblik J",
        "doi": "10.1016/j.ajem.2018.05.050",
        "id": "madsen-2019",
        "pmid": "29848460",
        "source": "Am J Emerg Med. 2019;37(2):281-285 (Epub 2018 May 24)",
        "title": "Impact of altitude-adjusted hypoxia on the Pulmonary Embolism Rule-out Criteria."
      },
      "formula": "perc_altitude",
      "formula_expression": "PERC-negative iff age < 50 and pulse < 100 bpm and SaO2 ≥ 90% and no unilateral leg swelling and no hemoptysis and no recent trauma or surgery and no prior PE or DVT and no hormone use",
      "criteria": [
        {
          "value": 40,
          "factor": "age_lt_50",
          "met": true
        },
        {
          "value": 80,
          "factor": "pulse_lt_100",
          "met": true
        },
        {
          "value": 90.0,
          "factor": "sao2_ge_90",
          "met": true
        },
        {
          "factor": "no_unilateral_leg_swelling",
          "met": true
        },
        {
          "factor": "no_hemoptysis",
          "met": true
        },
        {
          "factor": "no_recent_surgery_or_trauma",
          "met": true
        },
        {
          "factor": "no_prior_vte",
          "met": true
        },
        {
          "factor": "no_estrogen_use",
          "met": true
        }
      ],
      "perc_negative": true
    }
  ]
}

Response

Field Type Description
formula string perc_altitude
formula_expression string Eight Kline factors with Madsen 2019 SaO2 ≥ 90% hypoxia threshold
perc_negative boolean true only when all eight criteria are met. Not a diagnosis.
criteria array Per-factor rows with factor, met, and value when numeric
citation object Madsen 2019 Am J Emerg Med citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Madsen T, Jedick R, Teeples T, Carlson M, Steenblik J",
    "doi": "10.1016/j.ajem.2018.05.050",
    "id": "madsen-2019",
    "pmid": "29848460",
    "source": "Am J Emerg Med. 2019;37(2):281-285 (Epub 2018 May 24)",
    "title": "Impact of altitude-adjusted hypoxia on the Pulmonary Embolism Rule-out Criteria."
  },
  "formula": "perc_altitude",
  "formula_expression": "PERC-negative iff age < 50 and pulse < 100 bpm and SaO2 ≥ 90% and no unilateral leg swelling and no hemoptysis and no recent trauma or surgery and no prior PE or DVT and no hormone use",
  "criteria": [
    {
      "value": 40,
      "factor": "age_lt_50",
      "met": true
    },
    {
      "value": 80,
      "factor": "pulse_lt_100",
      "met": true
    },
    {
      "value": 90.0,
      "factor": "sao2_ge_90",
      "met": true
    },
    {
      "factor": "no_unilateral_leg_swelling",
      "met": true
    },
    {
      "factor": "no_hemoptysis",
      "met": true
    },
    {
      "factor": "no_recent_surgery_or_trauma",
      "met": true
    },
    {
      "factor": "no_prior_vte",
      "met": true
    },
    {
      "factor": "no_estrogen_use",
      "met": true
    }
  ],
  "perc_negative": true
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_perc_altitude Altitude-adjusted PERC needs age, heart_rate_bpm, spo2_percent, and the five Kline flags (Madsen 2019). Returned before settlement; you are not charged.
400 invalid_age age must be an integer from 18 to 120 Returned before settlement; you are not charged.
400 invalid_heart_rate heart_rate_bpm must be an integer from 30 to 220 Returned before settlement; you are not charged.
400 invalid_spo2 spo2_percent must be a number from 50 to 100. Returned before settlement; you are not charged.
400 invalid_flag boolean clinical flags must be true or false Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • PERC rule — Apply the Kline 2004 eight-factor pulmonary embolism rule-out criteria and return whether all eight are met (PERC-negative).
  • Wells PE — Compute the Wells pulmonary-embolism probability score and return three-tier and two-tier bands.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.