Infection / VTE · LIVE
Altitude-adjusted PERC
Apply the Madsen 2019 altitude-adjusted eight-factor pulmonary embolism rule-out criteria (hypoxia as O2 sat <90% at ~4980 ft) and return whether all eight are met (PERC-negative).
Markdown: /docs/perc-altitude.md · Canonical: https://magentlab.com/docs/perc-altitude
Not a medical device. Not a diagnosis, dose, or listing recommendation.
What it computes
Apply the Madsen 2019 altitude-adjusted eight-factor pulmonary embolism rule-out criteria (hypoxia as O2 sat <90% at ~4980 ft) and return whether all eight are met (PERC-negative).
When to use
When an agent already has a low pretest probability of PE, as in Kline, and the encounter is at altitude as studied by Madsen (chest pain and/or SOB at ~4980 ft), and needs a published altitude-adjusted PERC-negative result from caller-assigned findings.
When not to use
- Not a medical device.
- Not a PE diagnosis and not sea-level PERC (that is perc). Not a D-dimer protocol.
- Only for patients who already have a low pretest probability of pulmonary embolism, as in Kline. Madsen studied chest pain and/or SOB at altitude. magent does not assign pretest probability.
- The caller assigns age, pulse, SaO2, and the five clinical flags. magent does not measure vitals or examine the patient.
Formula
PERC-negative iff age < 50 and pulse < 100 bpm and SaO2 ≥ 90% and no unilateral leg swelling and no hemoptysis and no recent trauma or surgery and no prior PE or DVT and no hormone use
Citation
- Authors
- Madsen T, Jedick R, Teeples T, Carlson M, Steenblik J
- Source
- Am J Emerg Med. 2019;37(2):281-285 (Epub 2018 May 24)
Worked example
All eight criteria met at SaO2 90
Given:
age=40estrogen_use=falseheart_rate_bpm=80hemoptysis=falseprior_vte=falserecent_surgery_or_trauma=falsespo2_percent=90unilateral_leg_swelling=false
- Age 40 < 50; pulse 80 < 100; SaO2 90 ≥ 90 (meets altitude-adjusted hypoxia; would fail sea-level PERC >94)
- Five harmful findings absent
- PERC-negative
Age 50 fails the age criterion
Given:
age=50estrogen_use=falseheart_rate_bpm=80hemoptysis=falseprior_vte=falserecent_surgery_or_trauma=falsespo2_percent=90unilateral_leg_swelling=false
- Age 50 is not < 50
- PERC-negative is false
Also searched as
- altitude-adjusted PERC
- Madsen PERC
- PERC altitude
- altitude PERC rule
- hypoxia-adjusted PERC
- PERC 4980 ft
- altitude-adjusted pulmonary embolism rule-out
Try
Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.
Full URL: https://api.magentlab.com/api/calc/perc_altitude?age=40&heart_rate_bpm=80&spo2_percent=90&unilateral_leg_swelling=false&hemoptysis=false&recent_surgery_or_trauma=false&prior_vte=false&estrogen_use=false
Call
Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params
return HTTP 400 before any quote or charge.
curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/perc_altitude?age=40&heart_rate_bpm=80&spo2_percent=90&unilateral_leg_swelling=false&hemoptysis=false&recent_surgery_or_trauma=false&prior_vte=false&estrogen_use=false"
Parameters
| Name | Type | Required | Description |
|---|---|---|---|
age |
integer | required | Age in years (18-120). Criterion met when age < 50; 50 does not meet. |
heart_rate_bpm |
integer | required | Pulse in beats per minute (integer 30-220). Criterion met when pulse < 100; 100 does not meet. |
spo2_percent |
number | required | Oxygen saturation percent (50-100). Criterion met when SaO2 ≥ 90; 89.9 does not meet. Madsen 2019 altitude adjustment, not sea-level PERC >94. |
unilateral_leg_swelling |
boolean | required | Unilateral leg swelling. true or false as assigned by the caller. Criterion met when false. |
hemoptysis |
boolean | required | Hemoptysis. true or false as assigned by the caller. Criterion met when false. |
recent_surgery_or_trauma |
boolean | required | Recent trauma or surgery. true or false as assigned by the caller. Criterion met when false. |
prior_vte |
boolean | required | Prior PE or DVT. true or false as assigned by the caller. Criterion met when false. |
estrogen_use |
boolean | required | Hormone or exogenous estrogen use. true or false as assigned by the caller. Criterion met when false. |
Bulk (POST)
POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.
- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.
Example request (fixture)
{
"items": [
{
"age": "40",
"estrogen_use": "false",
"heart_rate_bpm": "80",
"hemoptysis": "false",
"prior_vte": "false",
"recent_surgery_or_trauma": "false",
"spo2_percent": "90",
"unilateral_leg_swelling": "false"
},
{
"age": "40",
"estrogen_use": "false",
"heart_rate_bpm": "80",
"hemoptysis": "false",
"prior_vte": "false",
"recent_surgery_or_trauma": "false",
"spo2_percent": "90",
"unilateral_leg_swelling": "false"
}
]
}
Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.
Example 200 (fixture)
{
"count": 2,
"path": "/api/calc/perc_altitude",
"items": [
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Madsen T, Jedick R, Teeples T, Carlson M, Steenblik J",
"doi": "10.1016/j.ajem.2018.05.050",
"id": "madsen-2019",
"pmid": "29848460",
"source": "Am J Emerg Med. 2019;37(2):281-285 (Epub 2018 May 24)",
"title": "Impact of altitude-adjusted hypoxia on the Pulmonary Embolism Rule-out Criteria."
},
"formula": "perc_altitude",
"formula_expression": "PERC-negative iff age < 50 and pulse < 100 bpm and SaO2 ≥ 90% and no unilateral leg swelling and no hemoptysis and no recent trauma or surgery and no prior PE or DVT and no hormone use",
"criteria": [
{
"value": 40,
"factor": "age_lt_50",
"met": true
},
{
"value": 80,
"factor": "pulse_lt_100",
"met": true
},
{
"value": 90.0,
"factor": "sao2_ge_90",
"met": true
},
{
"factor": "no_unilateral_leg_swelling",
"met": true
},
{
"factor": "no_hemoptysis",
"met": true
},
{
"factor": "no_recent_surgery_or_trauma",
"met": true
},
{
"factor": "no_prior_vte",
"met": true
},
{
"factor": "no_estrogen_use",
"met": true
}
],
"perc_negative": true
},
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Madsen T, Jedick R, Teeples T, Carlson M, Steenblik J",
"doi": "10.1016/j.ajem.2018.05.050",
"id": "madsen-2019",
"pmid": "29848460",
"source": "Am J Emerg Med. 2019;37(2):281-285 (Epub 2018 May 24)",
"title": "Impact of altitude-adjusted hypoxia on the Pulmonary Embolism Rule-out Criteria."
},
"formula": "perc_altitude",
"formula_expression": "PERC-negative iff age < 50 and pulse < 100 bpm and SaO2 ≥ 90% and no unilateral leg swelling and no hemoptysis and no recent trauma or surgery and no prior PE or DVT and no hormone use",
"criteria": [
{
"value": 40,
"factor": "age_lt_50",
"met": true
},
{
"value": 80,
"factor": "pulse_lt_100",
"met": true
},
{
"value": 90.0,
"factor": "sao2_ge_90",
"met": true
},
{
"factor": "no_unilateral_leg_swelling",
"met": true
},
{
"factor": "no_hemoptysis",
"met": true
},
{
"factor": "no_recent_surgery_or_trauma",
"met": true
},
{
"factor": "no_prior_vte",
"met": true
},
{
"factor": "no_estrogen_use",
"met": true
}
],
"perc_negative": true
}
]
}
Response
| Field | Type | Description |
|---|---|---|
formula |
string | perc_altitude |
formula_expression |
string | Eight Kline factors with Madsen 2019 SaO2 ≥ 90% hypoxia threshold |
perc_negative |
boolean | true only when all eight criteria are met. Not a diagnosis. |
criteria |
array | Per-factor rows with factor, met, and value when numeric |
citation |
object | Madsen 2019 Am J Emerg Med citation |
disclaimer |
string | Not-a-device notice |
Example JSON
Machine form of the same example. Frozen fixture. Not a live lookup.
{
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Madsen T, Jedick R, Teeples T, Carlson M, Steenblik J",
"doi": "10.1016/j.ajem.2018.05.050",
"id": "madsen-2019",
"pmid": "29848460",
"source": "Am J Emerg Med. 2019;37(2):281-285 (Epub 2018 May 24)",
"title": "Impact of altitude-adjusted hypoxia on the Pulmonary Embolism Rule-out Criteria."
},
"formula": "perc_altitude",
"formula_expression": "PERC-negative iff age < 50 and pulse < 100 bpm and SaO2 ≥ 90% and no unilateral leg swelling and no hemoptysis and no recent trauma or surgery and no prior PE or DVT and no hormone use",
"criteria": [
{
"value": 40,
"factor": "age_lt_50",
"met": true
},
{
"value": 80,
"factor": "pulse_lt_100",
"met": true
},
{
"value": 90.0,
"factor": "sao2_ge_90",
"met": true
},
{
"factor": "no_unilateral_leg_swelling",
"met": true
},
{
"factor": "no_hemoptysis",
"met": true
},
{
"factor": "no_recent_surgery_or_trauma",
"met": true
},
{
"factor": "no_prior_vte",
"met": true
},
{
"factor": "no_estrogen_use",
"met": true
}
],
"perc_negative": true
}
Client errors (HTTP 400)
Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.
| HTTP | Code | When |
|---|---|---|
| 400 | invalid_perc_altitude |
Altitude-adjusted PERC needs age, heart_rate_bpm, spo2_percent, and the five Kline flags (Madsen 2019). Returned before settlement; you are not charged. |
| 400 | invalid_age |
age must be an integer from 18 to 120 Returned before settlement; you are not charged. |
| 400 | invalid_heart_rate |
heart_rate_bpm must be an integer from 30 to 220 Returned before settlement; you are not charged. |
| 400 | invalid_spo2 |
spo2_percent must be a number from 50 to 100. Returned before settlement; you are not charged. |
| 400 | invalid_flag |
boolean clinical flags must be true or false Returned before settlement; you are not charged. |
| 400 | invalid_items |
POST body must be a JSON object with only an items array Returned before settlement; you are not charged. |
| 400 | invalid_item_count |
items must be an array of 1 to 25 objects Returned before settlement; you are not charged. |
| 400 | invalid_item |
each items entry must be a JSON object Returned before settlement; you are not charged. |
Related tools
- PERC rule — Apply the Kline 2004 eight-factor pulmonary embolism rule-out criteria and return whether all eight are met (PERC-negative).
- Wells PE — Compute the Wells pulmonary-embolism probability score and return three-tier and two-tier bands.
Payment
Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64
PAYMENT-REQUIRED
header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake
and shared payment errors: Payments.
Stdio MCP: /docs/mcp.
Guarantees
- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.