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Rome IV functional chest pain

Rome IV Chest Pain

Apply the Aziz 2016 Rome IV functional chest pain diagnostic criteria and return whether the published functional chest pain box holds (rome_iv_chest_pain).

LIVE $0.005 USDC GET /api/calc/rome_iv_chest_pain

Markdown: /docs/rome-iv-chest-pain.md · Canonical: https://magentlab.com/docs/rome-iv-chest-pain

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Aziz 2016 Rome IV functional chest pain diagnostic criteria and return whether the published functional chest pain box holds (rome_iv_chest_pain).

When to use

When an agent already has the six caller-assigned Aziz 2016 Rome IV functional chest pain flags and needs whether the published box holds. magent does not examine the patient, rule out ACS, or read manometry.

When not to use

Not a medical device.
Not a diagnosis. magent does not diagnose functional chest pain.
The caller assigns the six flags, including that cardiac causes are ruled out. magent does not examine the patient, rule out ACS, or read manometry.
This tool is Aziz 2016 Rome IV functional chest pain only. Not functional heartburn. Not reflux hypersensitivity. Not globus.

Formula

rome_iv_chest_pain iff retrosternal_chest_pain_or_discomfort and no_associated_heartburn_or_dysphagia and not_explained_by_gerd_or_eoe and no_major_esophageal_motor_disorder and fulfilled_last_3_months and onset_at_least_6_months (Aziz 2016 Rome IV functional chest pain)

Citation

Title: Esophageal Disorders
Authors: Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F
Source: Gastroenterology. 2016;150(6):1368-1379
DOI: 10.1053/j.gastro.2016.02.012

Worked example

All six required flags

Given: fulfilled_last_3_months=trueno_associated_heartburn_or_dysphagia=trueno_major_esophageal_motor_disorder=truenot_explained_by_gerd_or_eoe=trueonset_at_least_6_months=trueretrosternal_chest_pain_or_discomfort=true

Retrosternal chest pain or discomfort is true; cardiac causes ruled out by the caller
No associated heartburn or dysphagia is true
Symptoms are not explained by GERD or eosinophilic esophagitis
No major esophageal motor disorder is true
Criteria fulfilled for the last 3 months and onset at least 6 months prior are true
rome_iv_chest_pain is true

Five required flags without 6-month onset

Five required flags hold
Onset at least 6 months prior is false
rome_iv_chest_pain is false

Also searched as

Rome IV functional chest pain
Aziz 2016 functional chest pain
functional chest pain Rome IV
Rome IV chest pain
esophageal functional chest pain
functional chest pain criteria
Rome IV esophageal chest pain
noncardiac chest pain Rome IV

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/rome_iv_chest_pain?retrosternal_chest_pain_or_discomfort=true&no_associated_heartburn_or_dysphagia=true&not_explained_by_gerd_or_eoe=true&no_major_esophageal_motor_disorder=true&fulfilled_last_3_months=true&onset_at_least_6_months=true

Full URL: https://api.magentlab.com/api/calc/rome_iv_chest_pain?retrosternal_chest_pain_or_discomfort=true&no_associated_heartburn_or_dysphagia=true&not_explained_by_gerd_or_eoe=true&no_major_esophageal_motor_disorder=true&fulfilled_last_3_months=true&onset_at_least_6_months=true

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/rome_iv_chest_pain?retrosternal_chest_pain_or_discomfort=true&no_associated_heartburn_or_dysphagia=true&not_explained_by_gerd_or_eoe=true&no_major_esophageal_motor_disorder=true&fulfilled_last_3_months=true&onset_at_least_6_months=true"

Parameters

Name	Type	Required	Description
`retrosternal_chest_pain_or_discomfort`	boolean	required	Retrosternal chest pain or discomfort; cardiac causes ruled out by the caller (Aziz 2016). true or false as assigned by the caller. magent does not examine the patient or rule out ACS.
`no_associated_heartburn_or_dysphagia`	boolean	required	Absence of associated esophageal symptoms such as heartburn and dysphagia, as assigned (Aziz 2016). true or false as assigned by the caller. magent does not examine the patient.
`not_explained_by_gerd_or_eoe`	boolean	required	Symptoms not explained by GERD or eosinophilic esophagitis, as assigned (Aziz 2016). true or false as assigned by the caller. magent does not examine the patient.
`no_major_esophageal_motor_disorder`	boolean	required	Absence of a major esophageal motor disorder, as assigned (Aziz 2016). true or false as assigned by the caller. magent does not read manometry.
`fulfilled_last_3_months`	boolean	required	Criteria fulfilled for the last 3 months, as assigned (Aziz 2016). true or false as assigned by the caller. magent does not take a history.
`onset_at_least_6_months`	boolean	required	Symptom onset at least 6 months prior to diagnosis, as assigned (Aziz 2016). true or false as assigned by the caller. magent does not take a history.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/rome_iv_chest_pain Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "fulfilled_last_3_months": "true",
      "no_associated_heartburn_or_dysphagia": "true",
      "no_major_esophageal_motor_disorder": "true",
      "not_explained_by_gerd_or_eoe": "true",
      "onset_at_least_6_months": "true",
      "retrosternal_chest_pain_or_discomfort": "true"
    },
    {
      "fulfilled_last_3_months": "true",
      "no_associated_heartburn_or_dysphagia": "true",
      "no_major_esophageal_motor_disorder": "true",
      "not_explained_by_gerd_or_eoe": "true",
      "onset_at_least_6_months": "true",
      "retrosternal_chest_pain_or_discomfort": "true"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/rome_iv_chest_pain",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F",
        "doi": "10.1053/j.gastro.2016.02.012",
        "id": "aziz-2016",
        "pmid": "27144654",
        "source": "Gastroenterology. 2016;150(6):1368-1379",
        "title": "Esophageal Disorders"
      },
      "formula": "rome_iv_chest_pain",
      "formula_expression": "rome_iv_chest_pain iff retrosternal_chest_pain_or_discomfort and no_associated_heartburn_or_dysphagia and not_explained_by_gerd_or_eoe and no_major_esophageal_motor_disorder and fulfilled_last_3_months and onset_at_least_6_months (Aziz 2016 Rome IV functional chest pain)",
      "criteria": [
        {
          "factor": "retrosternal_chest_pain_or_discomfort",
          "met": true
        },
        {
          "factor": "no_associated_heartburn_or_dysphagia",
          "met": true
        },
        {
          "factor": "not_explained_by_gerd_or_eoe",
          "met": true
        },
        {
          "factor": "no_major_esophageal_motor_disorder",
          "met": true
        },
        {
          "factor": "fulfilled_last_3_months",
          "met": true
        },
        {
          "factor": "onset_at_least_6_months",
          "met": true
        }
      ],
      "rome_iv_chest_pain": true
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F",
        "doi": "10.1053/j.gastro.2016.02.012",
        "id": "aziz-2016",
        "pmid": "27144654",
        "source": "Gastroenterology. 2016;150(6):1368-1379",
        "title": "Esophageal Disorders"
      },
      "formula": "rome_iv_chest_pain",
      "formula_expression": "rome_iv_chest_pain iff retrosternal_chest_pain_or_discomfort and no_associated_heartburn_or_dysphagia and not_explained_by_gerd_or_eoe and no_major_esophageal_motor_disorder and fulfilled_last_3_months and onset_at_least_6_months (Aziz 2016 Rome IV functional chest pain)",
      "criteria": [
        {
          "factor": "retrosternal_chest_pain_or_discomfort",
          "met": true
        },
        {
          "factor": "no_associated_heartburn_or_dysphagia",
          "met": true
        },
        {
          "factor": "not_explained_by_gerd_or_eoe",
          "met": true
        },
        {
          "factor": "no_major_esophageal_motor_disorder",
          "met": true
        },
        {
          "factor": "fulfilled_last_3_months",
          "met": true
        },
        {
          "factor": "onset_at_least_6_months",
          "met": true
        }
      ],
      "rome_iv_chest_pain": true
    }
  ]
}

Response

Field	Type	Description
`formula`	string	rome_iv_chest_pain
`formula_expression`	string	Aziz 2016 Rome IV functional chest pain: retrosternal chest pain or discomfort, no associated heartburn or dysphagia, not explained by GERD or EoE, no major esophageal motor disorder, last-3-months criteria, and 6-month onset
`rome_iv_chest_pain`	boolean	true only when all six required flags hold. Not a diagnosis.
`criteria`	array	Per-factor rows with factor and met for the six required flags
`citation`	object	Aziz 2016 Gastroenterology citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F",
    "doi": "10.1053/j.gastro.2016.02.012",
    "id": "aziz-2016",
    "pmid": "27144654",
    "source": "Gastroenterology. 2016;150(6):1368-1379",
    "title": "Esophageal Disorders"
  },
  "formula": "rome_iv_chest_pain",
  "formula_expression": "rome_iv_chest_pain iff retrosternal_chest_pain_or_discomfort and no_associated_heartburn_or_dysphagia and not_explained_by_gerd_or_eoe and no_major_esophageal_motor_disorder and fulfilled_last_3_months and onset_at_least_6_months (Aziz 2016 Rome IV functional chest pain)",
  "criteria": [
    {
      "factor": "retrosternal_chest_pain_or_discomfort",
      "met": true
    },
    {
      "factor": "no_associated_heartburn_or_dysphagia",
      "met": true
    },
    {
      "factor": "not_explained_by_gerd_or_eoe",
      "met": true
    },
    {
      "factor": "no_major_esophageal_motor_disorder",
      "met": true
    },
    {
      "factor": "fulfilled_last_3_months",
      "met": true
    },
    {
      "factor": "onset_at_least_6_months",
      "met": true
    }
  ],
  "rome_iv_chest_pain": true
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_rome_iv_chest_pain`	Rome IV functional chest pain needs the Aziz 2016 esophageal chest-pain flags. Returned before settlement; you are not charged.
400	`invalid_flag`	boolean clinical flags must be true or false Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

Rome IV Heartburn — Apply the Aziz 2016 Rome IV functional heartburn diagnostic criteria and return whether the published functional heartburn box holds (rome_iv_heartburn).
Rome IV globus — Apply the Aziz 2016 Rome IV esophageal globus diagnostic criteria and return whether the published globus box holds (rome_iv_globus).

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.