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Rome IV globus

Apply the Aziz 2016 Rome IV esophageal globus diagnostic criteria and return whether the published globus box holds (rome_iv_globus).

LIVE $0.005 USDC GET /api/calc/rome_iv_globus

Markdown: /docs/rome-iv-globus.md · Canonical: https://magentlab.com/docs/rome-iv-globus

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Aziz 2016 Rome IV esophageal globus diagnostic criteria and return whether the published globus box holds (rome_iv_globus).

When to use

When an agent already has the eight caller-assigned Aziz 2016 Rome IV globus flags and needs whether the published globus box holds. magent does not examine the patient or read endoscopy.

When not to use

  • Not a medical device.
  • Not a diagnosis. magent does not diagnose globus.
  • The caller assigns the eight flags. magent does not examine the patient or read endoscopy.
  • This tool is Aziz 2016 Rome IV esophageal globus only. Not functional heartburn. Not Rome IV IBS (Mearin 2016). Not cannabinoid hyperemesis syndrome (CHS).

Formula

rome_iv_globus iff nonpainful_lump_or_foreign_body_sensation and occurrence_between_meals and no_dysphagia_or_odynophagia and no_gastric_inlet_patch and not_explained_by_gerd_or_eoe and no_major_esophageal_motor_disorder and fulfilled_last_3_months and onset_at_least_6_months (Aziz 2016 Rome IV esophageal globus)

Citation

Title
Esophageal Disorders
Authors
Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F
Source
Gastroenterology. 2016;150(6):1368-1379
DOI
10.1053/j.gastro.2016.02.012

Worked example

All eight required flags

Given: fulfilled_last_3_months=trueno_dysphagia_or_odynophagia=trueno_gastric_inlet_patch=trueno_major_esophageal_motor_disorder=truenonpainful_lump_or_foreign_body_sensation=truenot_explained_by_gerd_or_eoe=trueoccurrence_between_meals=trueonset_at_least_6_months=true

  1. Nonpainful lump or foreign-body sensation and occurrence between meals are true
  2. No dysphagia or odynophagia, no gastric inlet patch, not explained by GERD or EoE, and no major esophageal motor disorder are true
  3. Criteria fulfilled for the last 3 months and onset at least 6 months prior are true
  4. rome_iv_globus is true

Seven required flags without 6-month onset

Given: fulfilled_last_3_months=trueno_dysphagia_or_odynophagia=trueno_gastric_inlet_patch=trueno_major_esophageal_motor_disorder=truenonpainful_lump_or_foreign_body_sensation=truenot_explained_by_gerd_or_eoe=trueoccurrence_between_meals=trueonset_at_least_6_months=false

  1. Seven required flags hold
  2. Onset at least 6 months prior is false
  3. rome_iv_globus is false

Also searched as

  • Rome IV globus
  • Rome IV globus sensation
  • globus pharyngeus
  • Aziz 2016 globus
  • esophageal globus criteria
  • lump in throat Rome IV
  • Rome IV esophageal globus
  • globus diagnostic criteria

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/rome_iv_globus?nonpainful_lump_or_foreign_body_sensation=true&occurrence_between_meals=true&no_dysphagia_or_odynophagia=true&no_gastric_inlet_patch=true&not_explained_by_gerd_or_eoe=true&no_major_esophageal_motor_disorder=true&fulfilled_last_3_months=true&onset_at_least_6_months=true

Full URL: https://api.magentlab.com/api/calc/rome_iv_globus?nonpainful_lump_or_foreign_body_sensation=true&occurrence_between_meals=true&no_dysphagia_or_odynophagia=true&no_gastric_inlet_patch=true&not_explained_by_gerd_or_eoe=true&no_major_esophageal_motor_disorder=true&fulfilled_last_3_months=true&onset_at_least_6_months=true

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge. 

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/rome_iv_globus?nonpainful_lump_or_foreign_body_sensation=true&occurrence_between_meals=true&no_dysphagia_or_odynophagia=true&no_gastric_inlet_patch=true&not_explained_by_gerd_or_eoe=true&no_major_esophageal_motor_disorder=true&fulfilled_last_3_months=true&onset_at_least_6_months=true"

Parameters

Name Type Required Description
nonpainful_lump_or_foreign_body_sensation boolean required Persistent or intermittent, nonpainful sensation of a lump or foreign body in the throat (Aziz 2016). true or false as assigned by the caller. magent does not examine the patient.
occurrence_between_meals boolean required Occurrence of the sensation between meals (Aziz 2016). true or false as assigned by the caller. magent does not take a history.
no_dysphagia_or_odynophagia boolean required Absence of dysphagia or odynophagia (Aziz 2016). true or false as assigned by the caller. magent does not examine the patient.
no_gastric_inlet_patch boolean required Absence of a gastric inlet patch in the proximal esophagus (Aziz 2016). true or false as assigned by the caller. magent does not read endoscopy.
not_explained_by_gerd_or_eoe boolean required Absence of evidence that gastroesophageal reflux or eosinophilic esophagitis is the cause of the symptom (Aziz 2016). true or false as assigned by the caller. magent does not read endoscopy.
no_major_esophageal_motor_disorder boolean required Absence of major esophageal motor disorders (achalasia/EGJ outflow obstruction, diffuse esophageal spasm, jackhammer esophagus, absent peristalsis) (Aziz 2016). true or false as assigned by the caller. magent does not interpret manometry.
fulfilled_last_3_months boolean required Criteria fulfilled for the last 3 months, as assigned (Aziz 2016). true or false as assigned by the caller. magent does not take a history.
onset_at_least_6_months boolean required Symptom onset at least 6 months prior to diagnosis, as assigned (Aziz 2016). true or false as assigned by the caller. magent does not take a history.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/rome_iv_globus Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "fulfilled_last_3_months": "true",
      "no_dysphagia_or_odynophagia": "true",
      "no_gastric_inlet_patch": "true",
      "no_major_esophageal_motor_disorder": "true",
      "nonpainful_lump_or_foreign_body_sensation": "true",
      "not_explained_by_gerd_or_eoe": "true",
      "occurrence_between_meals": "true",
      "onset_at_least_6_months": "true"
    },
    {
      "fulfilled_last_3_months": "true",
      "no_dysphagia_or_odynophagia": "true",
      "no_gastric_inlet_patch": "true",
      "no_major_esophageal_motor_disorder": "true",
      "nonpainful_lump_or_foreign_body_sensation": "true",
      "not_explained_by_gerd_or_eoe": "true",
      "occurrence_between_meals": "true",
      "onset_at_least_6_months": "true"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/rome_iv_globus",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F",
        "doi": "10.1053/j.gastro.2016.02.012",
        "id": "aziz-2016",
        "pmid": "27144654",
        "source": "Gastroenterology. 2016;150(6):1368-1379",
        "title": "Esophageal Disorders"
      },
      "formula": "rome_iv_globus",
      "formula_expression": "rome_iv_globus iff nonpainful_lump_or_foreign_body_sensation and occurrence_between_meals and no_dysphagia_or_odynophagia and no_gastric_inlet_patch and not_explained_by_gerd_or_eoe and no_major_esophageal_motor_disorder and fulfilled_last_3_months and onset_at_least_6_months (Aziz 2016 Rome IV esophageal globus)",
      "criteria": [
        {
          "factor": "nonpainful_lump_or_foreign_body_sensation",
          "met": true
        },
        {
          "factor": "occurrence_between_meals",
          "met": true
        },
        {
          "factor": "no_dysphagia_or_odynophagia",
          "met": true
        },
        {
          "factor": "no_gastric_inlet_patch",
          "met": true
        },
        {
          "factor": "not_explained_by_gerd_or_eoe",
          "met": true
        },
        {
          "factor": "no_major_esophageal_motor_disorder",
          "met": true
        },
        {
          "factor": "fulfilled_last_3_months",
          "met": true
        },
        {
          "factor": "onset_at_least_6_months",
          "met": true
        }
      ],
      "rome_iv_globus": true
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F",
        "doi": "10.1053/j.gastro.2016.02.012",
        "id": "aziz-2016",
        "pmid": "27144654",
        "source": "Gastroenterology. 2016;150(6):1368-1379",
        "title": "Esophageal Disorders"
      },
      "formula": "rome_iv_globus",
      "formula_expression": "rome_iv_globus iff nonpainful_lump_or_foreign_body_sensation and occurrence_between_meals and no_dysphagia_or_odynophagia and no_gastric_inlet_patch and not_explained_by_gerd_or_eoe and no_major_esophageal_motor_disorder and fulfilled_last_3_months and onset_at_least_6_months (Aziz 2016 Rome IV esophageal globus)",
      "criteria": [
        {
          "factor": "nonpainful_lump_or_foreign_body_sensation",
          "met": true
        },
        {
          "factor": "occurrence_between_meals",
          "met": true
        },
        {
          "factor": "no_dysphagia_or_odynophagia",
          "met": true
        },
        {
          "factor": "no_gastric_inlet_patch",
          "met": true
        },
        {
          "factor": "not_explained_by_gerd_or_eoe",
          "met": true
        },
        {
          "factor": "no_major_esophageal_motor_disorder",
          "met": true
        },
        {
          "factor": "fulfilled_last_3_months",
          "met": true
        },
        {
          "factor": "onset_at_least_6_months",
          "met": true
        }
      ],
      "rome_iv_globus": true
    }
  ]
}

Response

Field Type Description
formula string rome_iv_globus
formula_expression string Aziz 2016 Rome IV esophageal globus: nonpainful lump or foreign-body sensation, occurrence between meals, no dysphagia or odynophagia, no gastric inlet patch, not explained by GERD or EoE, no major esophageal motor disorder, last-3-months criteria, and 6-month onset
rome_iv_globus boolean true only when all eight required flags hold. Not a diagnosis.
criteria array Per-factor rows with factor and met for the eight required flags
citation object Aziz 2016 Gastroenterology citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup. 

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F",
    "doi": "10.1053/j.gastro.2016.02.012",
    "id": "aziz-2016",
    "pmid": "27144654",
    "source": "Gastroenterology. 2016;150(6):1368-1379",
    "title": "Esophageal Disorders"
  },
  "formula": "rome_iv_globus",
  "formula_expression": "rome_iv_globus iff nonpainful_lump_or_foreign_body_sensation and occurrence_between_meals and no_dysphagia_or_odynophagia and no_gastric_inlet_patch and not_explained_by_gerd_or_eoe and no_major_esophageal_motor_disorder and fulfilled_last_3_months and onset_at_least_6_months (Aziz 2016 Rome IV esophageal globus)",
  "criteria": [
    {
      "factor": "nonpainful_lump_or_foreign_body_sensation",
      "met": true
    },
    {
      "factor": "occurrence_between_meals",
      "met": true
    },
    {
      "factor": "no_dysphagia_or_odynophagia",
      "met": true
    },
    {
      "factor": "no_gastric_inlet_patch",
      "met": true
    },
    {
      "factor": "not_explained_by_gerd_or_eoe",
      "met": true
    },
    {
      "factor": "no_major_esophageal_motor_disorder",
      "met": true
    },
    {
      "factor": "fulfilled_last_3_months",
      "met": true
    },
    {
      "factor": "onset_at_least_6_months",
      "met": true
    }
  ],
  "rome_iv_globus": true
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_rome_iv_globus Rome IV globus needs the Aziz 2016 esophageal globus flags. Returned before settlement; you are not charged.
400 invalid_flag boolean clinical flags must be true or false Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • Rome IV Heartburn — Apply the Aziz 2016 Rome IV functional heartburn diagnostic criteria and return whether the published functional heartburn box holds (rome_iv_heartburn).
  • Rome IV FD — Apply the Stanghellini 2016 Rome IV B1 functional dyspepsia criteria and return whether PDS (B1a), EPS (B1b), and the published FD box hold (rome_iv_fd).

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.