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Rome IV functional dyspepsia

Rome IV FD

Apply the Stanghellini 2016 Rome IV B1 functional dyspepsia criteria and return whether PDS (B1a), EPS (B1b), and the published FD box hold (rome_iv_fd).

LIVE $0.005 USDC GET /api/calc/rome_iv_fd

Markdown: /docs/rome-iv-fd.md · Canonical: https://magentlab.com/docs/rome-iv-fd

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Stanghellini 2016 Rome IV B1 functional dyspepsia criteria and return whether PDS (B1a), EPS (B1b), and the published FD box hold (rome_iv_fd).

When to use

When an agent already has the six caller-assigned Stanghellini 2016 Rome IV B1 flags and needs whether PDS, EPS, and the published FD box hold. magent does not examine the patient.

When not to use

Not a medical device.
Not a diagnosis. magent does not diagnose functional dyspepsia, PDS, or EPS.
The caller assigns the six flags, including PDS frequency (at least 3 days per week), EPS frequency (at least 1 day per week), and whether structural disease is absent at upper endoscopy. magent does not examine the patient or interpret endoscopy.
This tool is Stanghellini 2016 Rome IV B1 functional dyspepsia with B1a PDS and/or B1b EPS only. Overlap is allowed. Meeting cardinal symptoms without a subtype is not enough. Not Rome III dyspepsia. Not Rome IV IBS (Mearin 2016). Does not implement belching disorders, cannabinoid hyperemesis, or rumination.

Formula

rome_iv_fd iff criteria_last_3_months_onset_6_months and no_structural_disease and (pds or eps); pds iff bothersome_postprandial_fullness_ge_3_days_week or bothersome_early_satiation_ge_3_days_week; eps iff bothersome_epigastric_pain_ge_1_day_week or bothersome_epigastric_burning_ge_1_day_week (Stanghellini 2016 Rome IV B1 functional dyspepsia)

Citation

Title: Gastroduodenal Disorders
Authors: Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, Talley NJ
Source: Gastroenterology. 2016;150(6):1380-1392
DOI: 10.1053/j.gastro.2016.02.011

Worked example

Timing, no structural disease, and PDS fullness only

Given: bothersome_early_satiation_ge_3_days_week=falsebothersome_epigastric_burning_ge_1_day_week=falsebothersome_epigastric_pain_ge_1_day_week=falsebothersome_postprandial_fullness_ge_3_days_week=truecriteria_last_3_months_onset_6_months=trueno_structural_disease=true

Criteria fulfilled for the last 3 months with onset at least 6 months prior is true
No structural disease likely to explain the symptoms is true
Bothersome postprandial fullness at least 3 days per week is true; early satiation, epigastric pain, and burning are false
pds is true, eps is false, rome_iv_fd is true

Timing and no structural disease without PDS or EPS

Given: bothersome_early_satiation_ge_3_days_week=falsebothersome_epigastric_burning_ge_1_day_week=falsebothersome_epigastric_pain_ge_1_day_week=falsebothersome_postprandial_fullness_ge_3_days_week=falsecriteria_last_3_months_onset_6_months=trueno_structural_disease=true

Timing and no structural disease hold
All four B1a/B1b items are false (pds false, eps false)
rome_iv_fd is false because B1 requires B1a and/or B1b

Also searched as

Rome IV functional dyspepsia
Rome IV FD
Stanghellini 2016 dyspepsia
postprandial distress syndrome
epigastric pain syndrome
Rome IV B1
PDS EPS dyspepsia
functional dyspepsia criteria

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/rome_iv_fd?criteria_last_3_months_onset_6_months=true&no_structural_disease=true&bothersome_postprandial_fullness_ge_3_days_week=true&bothersome_early_satiation_ge_3_days_week=false&bothersome_epigastric_pain_ge_1_day_week=false&bothersome_epigastric_burning_ge_1_day_week=false

Full URL: https://api.magentlab.com/api/calc/rome_iv_fd?criteria_last_3_months_onset_6_months=true&no_structural_disease=true&bothersome_postprandial_fullness_ge_3_days_week=true&bothersome_early_satiation_ge_3_days_week=false&bothersome_epigastric_pain_ge_1_day_week=false&bothersome_epigastric_burning_ge_1_day_week=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/rome_iv_fd?criteria_last_3_months_onset_6_months=true&no_structural_disease=true&bothersome_postprandial_fullness_ge_3_days_week=true&bothersome_early_satiation_ge_3_days_week=false&bothersome_epigastric_pain_ge_1_day_week=false&bothersome_epigastric_burning_ge_1_day_week=false"

Parameters

Name	Type	Required	Description
`criteria_last_3_months_onset_6_months`	boolean	required	Criteria fulfilled for the last 3 months with symptom onset at least 6 months prior to diagnosis, as assigned (Stanghellini 2016 B1). true or false as assigned by the caller. magent does not take a history.
`no_structural_disease`	boolean	required	No evidence of structural disease (including at upper endoscopy) likely to explain the symptoms, as assigned by the caller (Stanghellini 2016 B1). true or false. magent does not examine the patient or interpret endoscopy.
`bothersome_postprandial_fullness_ge_3_days_week`	boolean	required	Bothersome postprandial fullness at least 3 days per week (B1a PDS item; one or both PDS items required for PDS). true or false as assigned by the caller. magent does not examine the patient.
`bothersome_early_satiation_ge_3_days_week`	boolean	required	Bothersome early satiation at least 3 days per week (B1a PDS item; one or both PDS items required for PDS). true or false as assigned by the caller. magent does not examine the patient.
`bothersome_epigastric_pain_ge_1_day_week`	boolean	required	Bothersome epigastric pain at least 1 day per week (B1b EPS item; one or both EPS items required for EPS). true or false as assigned by the caller. magent does not examine the patient.
`bothersome_epigastric_burning_ge_1_day_week`	boolean	required	Bothersome epigastric burning at least 1 day per week (B1b EPS item; one or both EPS items required for EPS). true or false as assigned by the caller. magent does not examine the patient.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/rome_iv_fd Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "bothersome_early_satiation_ge_3_days_week": "false",
      "bothersome_epigastric_burning_ge_1_day_week": "false",
      "bothersome_epigastric_pain_ge_1_day_week": "false",
      "bothersome_postprandial_fullness_ge_3_days_week": "true",
      "criteria_last_3_months_onset_6_months": "true",
      "no_structural_disease": "true"
    },
    {
      "bothersome_early_satiation_ge_3_days_week": "false",
      "bothersome_epigastric_burning_ge_1_day_week": "false",
      "bothersome_epigastric_pain_ge_1_day_week": "false",
      "bothersome_postprandial_fullness_ge_3_days_week": "true",
      "criteria_last_3_months_onset_6_months": "true",
      "no_structural_disease": "true"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/rome_iv_fd",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, Talley NJ",
        "doi": "10.1053/j.gastro.2016.02.011",
        "id": "stanghellini-2016",
        "pmid": "27147122",
        "source": "Gastroenterology. 2016;150(6):1380-1392",
        "title": "Gastroduodenal Disorders"
      },
      "formula": "rome_iv_fd",
      "formula_expression": "rome_iv_fd iff criteria_last_3_months_onset_6_months and no_structural_disease and (pds or eps); pds iff bothersome_postprandial_fullness_ge_3_days_week or bothersome_early_satiation_ge_3_days_week; eps iff bothersome_epigastric_pain_ge_1_day_week or bothersome_epigastric_burning_ge_1_day_week (Stanghellini 2016 Rome IV B1 functional dyspepsia)",
      "criteria": [
        {
          "factor": "criteria_last_3_months_onset_6_months",
          "met": true
        },
        {
          "factor": "no_structural_disease",
          "met": true
        },
        {
          "factor": "bothersome_postprandial_fullness_ge_3_days_week",
          "met": true
        },
        {
          "factor": "bothersome_early_satiation_ge_3_days_week",
          "met": false
        },
        {
          "factor": "pds",
          "met": true
        },
        {
          "factor": "bothersome_epigastric_pain_ge_1_day_week",
          "met": false
        },
        {
          "factor": "bothersome_epigastric_burning_ge_1_day_week",
          "met": false
        },
        {
          "factor": "eps",
          "met": false
        },
        {
          "factor": "pds_or_eps",
          "met": true
        }
      ],
      "eps": false,
      "pds": true,
      "rome_iv_fd": true
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, Talley NJ",
        "doi": "10.1053/j.gastro.2016.02.011",
        "id": "stanghellini-2016",
        "pmid": "27147122",
        "source": "Gastroenterology. 2016;150(6):1380-1392",
        "title": "Gastroduodenal Disorders"
      },
      "formula": "rome_iv_fd",
      "formula_expression": "rome_iv_fd iff criteria_last_3_months_onset_6_months and no_structural_disease and (pds or eps); pds iff bothersome_postprandial_fullness_ge_3_days_week or bothersome_early_satiation_ge_3_days_week; eps iff bothersome_epigastric_pain_ge_1_day_week or bothersome_epigastric_burning_ge_1_day_week (Stanghellini 2016 Rome IV B1 functional dyspepsia)",
      "criteria": [
        {
          "factor": "criteria_last_3_months_onset_6_months",
          "met": true
        },
        {
          "factor": "no_structural_disease",
          "met": true
        },
        {
          "factor": "bothersome_postprandial_fullness_ge_3_days_week",
          "met": true
        },
        {
          "factor": "bothersome_early_satiation_ge_3_days_week",
          "met": false
        },
        {
          "factor": "pds",
          "met": true
        },
        {
          "factor": "bothersome_epigastric_pain_ge_1_day_week",
          "met": false
        },
        {
          "factor": "bothersome_epigastric_burning_ge_1_day_week",
          "met": false
        },
        {
          "factor": "eps",
          "met": false
        },
        {
          "factor": "pds_or_eps",
          "met": true
        }
      ],
      "eps": false,
      "pds": true,
      "rome_iv_fd": true
    }
  ]
}

Response

Field	Type	Description
`formula`	string	rome_iv_fd
`formula_expression`	string	Stanghellini 2016 Rome IV B1: last 3 months with 6-month onset, no structural disease, and PDS (B1a) and/or EPS (B1b)
`pds`	boolean	true when either bothersome postprandial fullness or bothersome early satiation holds at least 3 days per week (B1a). Not a diagnosis.
`eps`	boolean	true when either bothersome epigastric pain or bothersome epigastric burning holds at least 1 day per week (B1b). Not a diagnosis.
`rome_iv_fd`	boolean	true only when timing, no structural disease, and PDS and/or EPS all hold. Cardinal symptoms without a subtype are not enough. Not a diagnosis.
`criteria`	array	Per-factor rows with factor and met; includes PDS items, EPS items, pds, eps, and pds_or_eps
`citation`	object	Stanghellini 2016 Gastroenterology citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, Talley NJ",
    "doi": "10.1053/j.gastro.2016.02.011",
    "id": "stanghellini-2016",
    "pmid": "27147122",
    "source": "Gastroenterology. 2016;150(6):1380-1392",
    "title": "Gastroduodenal Disorders"
  },
  "formula": "rome_iv_fd",
  "formula_expression": "rome_iv_fd iff criteria_last_3_months_onset_6_months and no_structural_disease and (pds or eps); pds iff bothersome_postprandial_fullness_ge_3_days_week or bothersome_early_satiation_ge_3_days_week; eps iff bothersome_epigastric_pain_ge_1_day_week or bothersome_epigastric_burning_ge_1_day_week (Stanghellini 2016 Rome IV B1 functional dyspepsia)",
  "criteria": [
    {
      "factor": "criteria_last_3_months_onset_6_months",
      "met": true
    },
    {
      "factor": "no_structural_disease",
      "met": true
    },
    {
      "factor": "bothersome_postprandial_fullness_ge_3_days_week",
      "met": true
    },
    {
      "factor": "bothersome_early_satiation_ge_3_days_week",
      "met": false
    },
    {
      "factor": "pds",
      "met": true
    },
    {
      "factor": "bothersome_epigastric_pain_ge_1_day_week",
      "met": false
    },
    {
      "factor": "bothersome_epigastric_burning_ge_1_day_week",
      "met": false
    },
    {
      "factor": "eps",
      "met": false
    },
    {
      "factor": "pds_or_eps",
      "met": true
    }
  ],
  "eps": false,
  "pds": true,
  "rome_iv_fd": true
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_flag`	boolean clinical flags must be true or false Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

Rome IV IBS — Apply the Mearin 2016 Rome IV IBS diagnostic criteria and return supporting_features_met (0-3) and whether the published IBS box holds (rome_iv_ibs).
Rome III IBS — Apply the Longstreth 2006 Rome III IBS diagnostic criteria and return supporting_features_met (0-3) and whether the published IBS box holds (rome_iii_ibs).

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.