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Rome IV functional diarrhea

Rome IV Diarrhea

Apply the Mearin 2016 Rome IV C3 functional diarrhea criteria and return whether the published C3 box holds (rome_iv_diarrhea).

LIVE $0.005 USDC GET /api/calc/rome_iv_diarrhea

Markdown: /docs/rome-iv-diarrhea.md · Canonical: https://magentlab.com/docs/rome-iv-diarrhea

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Mearin 2016 Rome IV C3 functional diarrhea criteria and return whether the published C3 box holds (rome_iv_diarrhea).

When to use

When an agent already has the three caller-assigned Rome IV C3 flags as in Mearin 2016 and needs whether the published functional diarrhea box holds. magent does not examine the patient.

When not to use

Not a medical device.
Not a diagnosis. magent does not diagnose functional diarrhea.
The caller assigns the three flags. magent does not examine the patient.
This tool is adult Rome IV C3 functional diarrhea only. Not child G5, not IBS-D, not Rome IV IBS (Mearin 2016 IBS box), not Manning, and not functional constipation.

Formula

rome_iv_diarrhea iff criteria_last_3_months_onset_6_months and loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating and insufficient_criteria_for_ibs_d (Mearin 2016 Rome IV C3 functional diarrhea)

Citation

Title: Bowel Disorders
Authors: Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller RC
Source: Gastroenterology. 2016;150(6):1393-1407
DOI: 10.1053/j.gastro.2016.02.031

Worked example

Timing, loose or watery stools without pain or bloating, and not IBS-D

Given: criteria_last_3_months_onset_6_months=trueinsufficient_criteria_for_ibs_d=trueloose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating=true

Criteria fulfilled for the last 3 months with onset at least 6 months prior is true
Loose or watery stools without predominant abdominal pain or bothersome bloating in more than 25% of stools is true
Insufficient criteria for diarrhea-predominant IBS is true
rome_iv_diarrhea is true

Timing and loose stools with IBS-D criteria met

Given: criteria_last_3_months_onset_6_months=trueinsufficient_criteria_for_ibs_d=falseloose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating=true

Timing and loose or watery stools without predominant pain or bloating hold
Insufficient criteria for diarrhea-predominant IBS is false
rome_iv_diarrhea is false

Also searched as

Rome IV functional diarrhea
Rome IV C3
Mearin 2016 diarrhea
functional diarrhea criteria
Rome IV diarrhea
adult functional diarrhea
diarrhea Rome IV
Mearin C3 functional diarrhea

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/rome_iv_diarrhea?criteria_last_3_months_onset_6_months=true&loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating=true&insufficient_criteria_for_ibs_d=true

Full URL: https://api.magentlab.com/api/calc/rome_iv_diarrhea?criteria_last_3_months_onset_6_months=true&loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating=true&insufficient_criteria_for_ibs_d=true

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/rome_iv_diarrhea?criteria_last_3_months_onset_6_months=true&loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating=true&insufficient_criteria_for_ibs_d=true"

Parameters

Name	Type	Required	Description
`criteria_last_3_months_onset_6_months`	boolean	required	Criteria fulfilled for the last 3 months with symptom onset at least 6 months prior to diagnosis, as assigned (Mearin 2016 C3). true or false as assigned by the caller. magent does not take a history.
`loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating`	boolean	required	Loose or watery stools, without predominant abdominal pain or bothersome bloating, occurring in more than 25% of stools (Mearin 2016 C3). true or false as assigned by the caller. magent does not inspect stool.
`insufficient_criteria_for_ibs_d`	boolean	required	Insufficient criteria for diarrhea-predominant IBS, as assigned by the caller (Mearin 2016 C3 excludes patients who meet IBS-D). true or false. magent does not apply the IBS box.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/rome_iv_diarrhea Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "criteria_last_3_months_onset_6_months": "true",
      "insufficient_criteria_for_ibs_d": "true",
      "loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating": "true"
    },
    {
      "criteria_last_3_months_onset_6_months": "true",
      "insufficient_criteria_for_ibs_d": "true",
      "loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating": "true"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/rome_iv_diarrhea",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller RC",
        "doi": "10.1053/j.gastro.2016.02.031",
        "id": "mearin-2016",
        "pmid": "27144627",
        "source": "Gastroenterology. 2016;150(6):1393-1407",
        "title": "Bowel Disorders"
      },
      "formula": "rome_iv_diarrhea",
      "formula_expression": "rome_iv_diarrhea iff criteria_last_3_months_onset_6_months and loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating and insufficient_criteria_for_ibs_d (Mearin 2016 Rome IV C3 functional diarrhea)",
      "criteria": [
        {
          "factor": "criteria_last_3_months_onset_6_months",
          "met": true
        },
        {
          "factor": "loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating",
          "met": true
        },
        {
          "factor": "insufficient_criteria_for_ibs_d",
          "met": true
        }
      ],
      "rome_iv_diarrhea": true
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller RC",
        "doi": "10.1053/j.gastro.2016.02.031",
        "id": "mearin-2016",
        "pmid": "27144627",
        "source": "Gastroenterology. 2016;150(6):1393-1407",
        "title": "Bowel Disorders"
      },
      "formula": "rome_iv_diarrhea",
      "formula_expression": "rome_iv_diarrhea iff criteria_last_3_months_onset_6_months and loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating and insufficient_criteria_for_ibs_d (Mearin 2016 Rome IV C3 functional diarrhea)",
      "criteria": [
        {
          "factor": "criteria_last_3_months_onset_6_months",
          "met": true
        },
        {
          "factor": "loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating",
          "met": true
        },
        {
          "factor": "insufficient_criteria_for_ibs_d",
          "met": true
        }
      ],
      "rome_iv_diarrhea": true
    }
  ]
}

Response

Field	Type	Description
`formula`	string	rome_iv_diarrhea
`formula_expression`	string	Mearin 2016 Rome IV C3: last 3 months with 6-month onset, loose or watery stools >25% without predominant pain or bloating, and insufficient IBS-D criteria
`rome_iv_diarrhea`	boolean	true only when timing, loose or watery stools without predominant pain or bloating in >25% of stools, and insufficient IBS-D criteria all hold. Not a diagnosis.
`criteria`	array	Per-factor rows with factor and met for the three C3 flags
`citation`	object	Mearin 2016 Gastroenterology citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller RC",
    "doi": "10.1053/j.gastro.2016.02.031",
    "id": "mearin-2016",
    "pmid": "27144627",
    "source": "Gastroenterology. 2016;150(6):1393-1407",
    "title": "Bowel Disorders"
  },
  "formula": "rome_iv_diarrhea",
  "formula_expression": "rome_iv_diarrhea iff criteria_last_3_months_onset_6_months and loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating and insufficient_criteria_for_ibs_d (Mearin 2016 Rome IV C3 functional diarrhea)",
  "criteria": [
    {
      "factor": "criteria_last_3_months_onset_6_months",
      "met": true
    },
    {
      "factor": "loose_or_watery_stools_gt_25_percent_without_predominant_pain_or_bloating",
      "met": true
    },
    {
      "factor": "insufficient_criteria_for_ibs_d",
      "met": true
    }
  ],
  "rome_iv_diarrhea": true
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_flag`	boolean clinical flags must be true or false Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

Rome IV IBS — Apply the Mearin 2016 Rome IV IBS diagnostic criteria and return supporting_features_met (0-3) and whether the published IBS box holds (rome_iv_ibs).
Rome IV FC — Apply the Mearin 2016 Rome IV C2 functional constipation criteria and return symptom_count (0-6) and whether the published C2 box holds (rome_iv_fc).
Bristol stool — Return the Lewis 1997 Bristol stool form scale type 1-7 from a caller-assigned integer, with the published form wording.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.