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Rome IV functional gallbladder disorder

Rome IV FGBD

Apply the Cotton 2016 Rome IV E1a functional gallbladder disorder diagnostic criteria and return whether the published E1a box holds (rome_iv_functional_gallbladder) plus the two supportive flags.

LIVE $0.005 USDC GET /api/calc/rome_iv_functional_gallbladder

Markdown: /docs/rome-iv-functional-gallbladder.md · Canonical: https://magentlab.com/docs/rome-iv-functional-gallbladder

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Cotton 2016 Rome IV E1a functional gallbladder disorder diagnostic criteria and return whether the published E1a box holds (rome_iv_functional_gallbladder) plus the two supportive flags.

When to use

When an agent already has the nine caller-assigned Cotton 2016 Rome IV E1a flags and needs whether the published functional gallbladder box holds. magent does not read ultrasound, EUS, or HIDA or decide cholecystectomy.

When not to use

• Not a medical device.
• Not a diagnosis. magent does not diagnose functional gallbladder disorder.
• The caller assigns the nine flags. magent does not read ultrasound, EUS, or HIDA scintigraphy, and does not decide cholecystectomy.
• This tool is Cotton 2016 Rome IV E1a functional gallbladder disorder only. Nested E1 biliary pain and absence of gallstones or other structural pathology are required. Low ejection fraction on gallbladder scintigraphy (GBEF) is supportive only and is not required. Normal liver enzymes, conjugated bilirubin, and amylase/lipase are supportive and not required. Not biliary SOD (E1b). Not pancreatic SOD (E2).

Formula

rome_iv_functional_gallbladder iff epigastric_or_ruq_pain and builds_to_steady_level_lasts_30_min_or_longer and occurring_at_different_intervals_not_daily and severe_enough_to_interrupt_activities_or_ed_visit and not_significantly_related_to_bowel_movements and not_significantly_relieved_by_postural_change_or_acid_suppression and absence_of_gallstones_or_other_structural_pathology (Cotton 2016 Rome IV E1a). low_ef_on_gallbladder_scintigraphy and normal_liver_enzymes_conjugated_bilirubin_amylase_lipase are supportive and not required.

Citation

Title

Gallbladder and Sphincter of Oddi Disorders

Authors

Cotton PB, Elta GH, Carter CR, Pasricha PJ, Corazziari ES

Source

Gastroenterology. 2016;150(6):1420-1429

DOI

10.1053/j.gastro.2016.02.033

Worked example

Also searched as

• Rome IV functional gallbladder
• Rome IV E1a
• Cotton 2016 functional gallbladder
• functional gallbladder disorder
• biliary dyskinesia Rome IV
• acalculous biliary pain
• low GBEF HIDA
• Rome IV gallbladder criteria

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/rome_iv_functional_gallbladder?epigastric_or_ruq_pain=true&builds_to_steady_level_lasts_30_min_or_longer=true&occurring_at_different_intervals_not_daily=true&severe_enough_to_interrupt_activities_or_ed_visit=true&not_significantly_related_to_bowel_movements=true&not_significantly_relieved_by_postural_change_or_acid_suppression=true&absence_of_gallstones_or_other_structural_pathology=true&low_ef_on_gallbladder_scintigraphy=true&normal_liver_enzymes_conjugated_bilirubin_amylase_lipase=true

Full URL: https://api.magentlab.com/api/calc/rome_iv_functional_gallbladder?epigastric_or_ruq_pain=true&builds_to_steady_level_lasts_30_min_or_longer=true&occurring_at_different_intervals_not_daily=true&severe_enough_to_interrupt_activities_or_ed_visit=true&not_significantly_related_to_bowel_movements=true&not_significantly_relieved_by_postural_change_or_acid_suppression=true&absence_of_gallstones_or_other_structural_pathology=true&low_ef_on_gallbladder_scintigraphy=true&normal_liver_enzymes_conjugated_bilirubin_amylase_lipase=true

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/rome_iv_functional_gallbladder?epigastric_or_ruq_pain=true&builds_to_steady_level_lasts_30_min_or_longer=true&occurring_at_different_intervals_not_daily=true&severe_enough_to_interrupt_activities_or_ed_visit=true&not_significantly_related_to_bowel_movements=true&not_significantly_relieved_by_postural_change_or_acid_suppression=true&absence_of_gallstones_or_other_structural_pathology=true&low_ef_on_gallbladder_scintigraphy=true&normal_liver_enzymes_conjugated_bilirubin_amylase_lipase=true"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/rome_iv_functional_gallbladder Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "absence_of_gallstones_or_other_structural_pathology": "true",
      "builds_to_steady_level_lasts_30_min_or_longer": "true",
      "epigastric_or_ruq_pain": "true",
      "low_ef_on_gallbladder_scintigraphy": "true",
      "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": "true",
      "not_significantly_related_to_bowel_movements": "true",
      "not_significantly_relieved_by_postural_change_or_acid_suppression": "true",
      "occurring_at_different_intervals_not_daily": "true",
      "severe_enough_to_interrupt_activities_or_ed_visit": "true"
    },
    {
      "absence_of_gallstones_or_other_structural_pathology": "true",
      "builds_to_steady_level_lasts_30_min_or_longer": "true",
      "epigastric_or_ruq_pain": "true",
      "low_ef_on_gallbladder_scintigraphy": "true",
      "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": "true",
      "not_significantly_related_to_bowel_movements": "true",
      "not_significantly_relieved_by_postural_change_or_acid_suppression": "true",
      "occurring_at_different_intervals_not_daily": "true",
      "severe_enough_to_interrupt_activities_or_ed_visit": "true"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/rome_iv_functional_gallbladder",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Cotton PB, Elta GH, Carter CR, Pasricha PJ, Corazziari ES",
        "doi": "10.1053/j.gastro.2016.02.033",
        "id": "cotton-2016",
        "pmid": "27144629",
        "source": "Gastroenterology. 2016;150(6):1420-1429",
        "title": "Gallbladder and Sphincter of Oddi Disorders"
      },
      "formula": "rome_iv_functional_gallbladder",
      "formula_expression": "rome_iv_functional_gallbladder iff epigastric_or_ruq_pain and builds_to_steady_level_lasts_30_min_or_longer and occurring_at_different_intervals_not_daily and severe_enough_to_interrupt_activities_or_ed_visit and not_significantly_related_to_bowel_movements and not_significantly_relieved_by_postural_change_or_acid_suppression and absence_of_gallstones_or_other_structural_pathology (Cotton 2016 Rome IV E1a). low_ef_on_gallbladder_scintigraphy and normal_liver_enzymes_conjugated_bilirubin_amylase_lipase are supportive and not required.",
      "criteria": [
        {
          "factor": "epigastric_or_ruq_pain",
          "met": true
        },
        {
          "factor": "builds_to_steady_level_lasts_30_min_or_longer",
          "met": true
        },
        {
          "factor": "occurring_at_different_intervals_not_daily",
          "met": true
        },
        {
          "factor": "severe_enough_to_interrupt_activities_or_ed_visit",
          "met": true
        },
        {
          "factor": "not_significantly_related_to_bowel_movements",
          "met": true
        },
        {
          "factor": "not_significantly_relieved_by_postural_change_or_acid_suppression",
          "met": true
        },
        {
          "factor": "absence_of_gallstones_or_other_structural_pathology",
          "met": true
        },
        {
          "factor": "low_ef_on_gallbladder_scintigraphy",
          "met": true
        },
        {
          "factor": "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase",
          "met": true
        }
      ],
      "low_ef_on_gallbladder_scintigraphy": true,
      "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
      "rome_iv_functional_gallbladder": true
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Cotton PB, Elta GH, Carter CR, Pasricha PJ, Corazziari ES",
        "doi": "10.1053/j.gastro.2016.02.033",
        "id": "cotton-2016",
        "pmid": "27144629",
        "source": "Gastroenterology. 2016;150(6):1420-1429",
        "title": "Gallbladder and Sphincter of Oddi Disorders"
      },
      "formula": "rome_iv_functional_gallbladder",
      "formula_expression": "rome_iv_functional_gallbladder iff epigastric_or_ruq_pain and builds_to_steady_level_lasts_30_min_or_longer and occurring_at_different_intervals_not_daily and severe_enough_to_interrupt_activities_or_ed_visit and not_significantly_related_to_bowel_movements and not_significantly_relieved_by_postural_change_or_acid_suppression and absence_of_gallstones_or_other_structural_pathology (Cotton 2016 Rome IV E1a). low_ef_on_gallbladder_scintigraphy and normal_liver_enzymes_conjugated_bilirubin_amylase_lipase are supportive and not required.",
      "criteria": [
        {
          "factor": "epigastric_or_ruq_pain",
          "met": true
        },
        {
          "factor": "builds_to_steady_level_lasts_30_min_or_longer",
          "met": true
        },
        {
          "factor": "occurring_at_different_intervals_not_daily",
          "met": true
        },
        {
          "factor": "severe_enough_to_interrupt_activities_or_ed_visit",
          "met": true
        },
        {
          "factor": "not_significantly_related_to_bowel_movements",
          "met": true
        },
        {
          "factor": "not_significantly_relieved_by_postural_change_or_acid_suppression",
          "met": true
        },
        {
          "factor": "absence_of_gallstones_or_other_structural_pathology",
          "met": true
        },
        {
          "factor": "low_ef_on_gallbladder_scintigraphy",
          "met": true
        },
        {
          "factor": "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase",
          "met": true
        }
      ],
      "low_ef_on_gallbladder_scintigraphy": true,
      "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
      "rome_iv_functional_gallbladder": true
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Cotton PB, Elta GH, Carter CR, Pasricha PJ, Corazziari ES",
    "doi": "10.1053/j.gastro.2016.02.033",
    "id": "cotton-2016",
    "pmid": "27144629",
    "source": "Gastroenterology. 2016;150(6):1420-1429",
    "title": "Gallbladder and Sphincter of Oddi Disorders"
  },
  "formula": "rome_iv_functional_gallbladder",
  "formula_expression": "rome_iv_functional_gallbladder iff epigastric_or_ruq_pain and builds_to_steady_level_lasts_30_min_or_longer and occurring_at_different_intervals_not_daily and severe_enough_to_interrupt_activities_or_ed_visit and not_significantly_related_to_bowel_movements and not_significantly_relieved_by_postural_change_or_acid_suppression and absence_of_gallstones_or_other_structural_pathology (Cotton 2016 Rome IV E1a). low_ef_on_gallbladder_scintigraphy and normal_liver_enzymes_conjugated_bilirubin_amylase_lipase are supportive and not required.",
  "criteria": [
    {
      "factor": "epigastric_or_ruq_pain",
      "met": true
    },
    {
      "factor": "builds_to_steady_level_lasts_30_min_or_longer",
      "met": true
    },
    {
      "factor": "occurring_at_different_intervals_not_daily",
      "met": true
    },
    {
      "factor": "severe_enough_to_interrupt_activities_or_ed_visit",
      "met": true
    },
    {
      "factor": "not_significantly_related_to_bowel_movements",
      "met": true
    },
    {
      "factor": "not_significantly_relieved_by_postural_change_or_acid_suppression",
      "met": true
    },
    {
      "factor": "absence_of_gallstones_or_other_structural_pathology",
      "met": true
    },
    {
      "factor": "low_ef_on_gallbladder_scintigraphy",
      "met": true
    },
    {
      "factor": "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase",
      "met": true
    }
  ],
  "low_ef_on_gallbladder_scintigraphy": true,
  "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
  "rome_iv_functional_gallbladder": true
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• Rome IV biliary pain — Apply the Cotton 2016 Rome IV E1 diagnostic criteria for biliary pain and return whether the published biliary-pain box holds (rome_iv_biliary_pain) plus three supportive flags.
• Rome IV biliary SOD — Apply the Cotton 2016 Rome IV E1b functional biliary sphincter of Oddi disorder diagnostic criteria and return whether the published E1b box holds (rome_iv_biliary_sod). Elevated liver enzymes XOR dilated bile duct is required. Supportive flags are reported and not required.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.