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ABIC score

ABIC

Compute the Dominguez 2008 ABIC score from age, bilirubin, creatinine, and INR for prognostic stratification of alcoholic hepatitis.

LIVE $0.005 USDC GET /api/calc/abic

Markdown: /docs/abic.md · Canonical: https://magentlab.com/docs/abic

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Dominguez 2008 ABIC score from age, bilirubin, creatinine, and INR for prognostic stratification of alcoholic hepatitis.

When to use

When an agent needs the published Dominguez 2008 ABIC arithmetic and must not invent a diagnosis of alcoholic hepatitis or a steroid or transplant order.

When not to use

Not a medical device. magent does not diagnose alcoholic hepatitis.
Not a steroid or transplant order.
Dominguez 2008 ABIC only. This is not Maddrey DF, GAHS, or Lille.

Formula

ABIC = (age * 0.1) + (bilirubin_mg_dl * 0.08) + (creatinine_mg_dl * 0.3) + (inr * 0.8)

Citation

Title: A new scoring system for prognostic stratification of patients with alcoholic hepatitis
Authors: Dominguez M, Rincón D, Abraldes JG, Miquel R, Colmenero J, Bellot P, García-Pagán JC, Fernández J, Marín P, Guarner C, Arroyo V, Bruguera M, Bañares R, Ginès P, Caballería J
Source: Am J Gastroenterol. 2008;103(11):2747-2756
DOI: 10.1111/j.1572-0241.2008.02104.x

Worked example

Age 50, bilirubin 10 mg/dL, creatinine 1 mg/dL, INR 1.5

Given: age=50bilirubin_mg_dl=10creatinine_mg_dl=1inr=1.5

age term = 50 × 0.1 = 5.0
bilirubin term = 10 × 0.08 = 0.8
creatinine term = 1 × 0.3 = 0.3
INR term = 1.5 × 0.8 = 1.2
ABIC = 5.0 + 0.8 + 0.3 + 1.2 = 7.30
6.71 ≤ 7.30 ≤ 9.0 → intermediate

Also searched as

ABIC score
age bilirubin INR creatinine
alcoholic hepatitis ABIC
Dominguez ABIC
ABIC prognostic score

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/abic?age=50&bilirubin_mg_dl=10&creatinine_mg_dl=1&inr=1.5

Full URL: https://api.magentlab.com/api/calc/abic?age=50&bilirubin_mg_dl=10&creatinine_mg_dl=1&inr=1.5

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/abic?age=50&bilirubin_mg_dl=10&creatinine_mg_dl=1&inr=1.5"

Parameters

Name	Type	Required	Description
`age`	integer	required	Age in years (integer 18-120).
`bilirubin_mg_dl`	number	optional	Total bilirubin in mg/dL (0.1-40). Provide this or bilirubin_umol_l, not both.
`bilirubin_umol_l`	number	optional	Total bilirubin in µmol/L (2-684). Converted as mg/dL = µmol/L / 17.1.
`creatinine_mg_dl`	number	optional	Serum creatinine in mg/dL (0.1-20). Provide this or creatinine_umol_l, not both.
`creatinine_umol_l`	number	optional	Serum creatinine in µmol/L (9-1768). Converted as mg/dL = µmol/L / 88.42.
`inr`	number	required	International normalized ratio (0.8-10).

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/abic Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "50",
      "bilirubin_mg_dl": "10",
      "creatinine_mg_dl": "1",
      "inr": "1.5"
    },
    {
      "age": "50",
      "bilirubin_mg_dl": "10",
      "creatinine_mg_dl": "1",
      "inr": "1.5"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/abic",
  "items": [
    {
      "age": 50,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Dominguez M, Rincón D, Abraldes JG, Miquel R, Colmenero J, Bellot P, García-Pagán JC, Fernández J, Marín P, Guarner C, Arroyo V, Bruguera M, Bañares R, Ginès P, Caballería J",
        "doi": "10.1111/j.1572-0241.2008.02104.x",
        "id": "dominguez-2008",
        "pmid": "18721242",
        "source": "Am J Gastroenterol. 2008;103(11):2747-2756",
        "title": "A new scoring system for prognostic stratification of patients with alcoholic hepatitis"
      },
      "formula": "abic",
      "formula_expression": "ABIC = (age * 0.1) + (bilirubin_mg_dl * 0.08) + (creatinine_mg_dl * 0.3) + (inr * 0.8)",
      "inr": 1.5,
      "abic_band": "intermediate",
      "bilirubin_mg_dl": 10.0,
      "abic_score": 7.3,
      "creatinine_mg_dl": 1.0
    },
    {
      "age": 50,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Dominguez M, Rincón D, Abraldes JG, Miquel R, Colmenero J, Bellot P, García-Pagán JC, Fernández J, Marín P, Guarner C, Arroyo V, Bruguera M, Bañares R, Ginès P, Caballería J",
        "doi": "10.1111/j.1572-0241.2008.02104.x",
        "id": "dominguez-2008",
        "pmid": "18721242",
        "source": "Am J Gastroenterol. 2008;103(11):2747-2756",
        "title": "A new scoring system for prognostic stratification of patients with alcoholic hepatitis"
      },
      "formula": "abic",
      "formula_expression": "ABIC = (age * 0.1) + (bilirubin_mg_dl * 0.08) + (creatinine_mg_dl * 0.3) + (inr * 0.8)",
      "inr": 1.5,
      "abic_band": "intermediate",
      "bilirubin_mg_dl": 10.0,
      "abic_score": 7.3,
      "creatinine_mg_dl": 1.0
    }
  ]
}

Response

Field	Type	Description
`formula`	string	abic
`formula_expression`	string	Exact expression used
`age`	integer	Age in years used
`bilirubin_mg_dl`	number	Normalized total bilirubin in mg/dL
`creatinine_mg_dl`	number	Normalized serum creatinine in mg/dL
`inr`	number	INR used
`abic_score`	number	Dominguez 2008 ABIC, 2 decimal places
`abic_band`	string	Dominguez 2008 bands on the rounded score: low (<6.71), intermediate (6.71-9.0), high (>9.0). Not a diagnosis or steroid order.
`citation`	object	Dominguez 2008 citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "age": 50,
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Dominguez M, Rincón D, Abraldes JG, Miquel R, Colmenero J, Bellot P, García-Pagán JC, Fernández J, Marín P, Guarner C, Arroyo V, Bruguera M, Bañares R, Ginès P, Caballería J",
    "doi": "10.1111/j.1572-0241.2008.02104.x",
    "id": "dominguez-2008",
    "pmid": "18721242",
    "source": "Am J Gastroenterol. 2008;103(11):2747-2756",
    "title": "A new scoring system for prognostic stratification of patients with alcoholic hepatitis"
  },
  "formula": "abic",
  "formula_expression": "ABIC = (age * 0.1) + (bilirubin_mg_dl * 0.08) + (creatinine_mg_dl * 0.3) + (inr * 0.8)",
  "inr": 1.5,
  "abic_band": "intermediate",
  "bilirubin_mg_dl": 10.0,
  "abic_score": 7.3,
  "creatinine_mg_dl": 1.0
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_age`	age must be an integer from 18 to 120 Returned before settlement; you are not charged.
400	`invalid_bilirubin`	bilirubin_mg_dl (0.1-40) or bilirubin_umol_l (2-684) is required Returned before settlement; you are not charged.
400	`invalid_creatinine`	creatinine_mg_dl (0.1-20) or creatinine_umol_l (9-1768) is required Returned before settlement; you are not charged.
400	`invalid_inr`	inr must be a number from 0.8 to 10 Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

Maddrey DF — Compute the 1978 Maddrey discriminant function from patient PT, control PT, and bilirubin.
GAHS — Compute the Forrest 2005 Glasgow alcoholic hepatitis score (5-12) and the published ≥9 band.
Lille score — Compute the Louvet 2007 Lille score from age, day-0 albumin, bilirubin on day 0 and day 7, creatinine, and PT seconds or INR. formula is required.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.