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BISAP

Compute the Wu 2008 BISAP score for early prediction of mortality in acute pancreatitis from BUN, caller-assigned impaired mental status, caller-assigned SIRS, age, and caller-assigned pleural effusion.

LIVE $0.005 USDC GET /api/calc/bisap

Markdown: /docs/bisap.md · Canonical: https://magentlab.com/docs/bisap

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

When to use

When an agent needs the published BISAP total and must not invent Ranson, APACHE II, CTSI, or mortality percentages.

When not to use

Not a diagnosis. magent does not diagnose acute pancreatitis or its severity.
Not Ranson, not APACHE II, and not CTSI. This tool is the Wu 2008 BISAP score only.
magent does not recompute SIRS from vitals. sirs is a caller-assigned flag.
magent does not assign mental status and does not take GCS. impaired_mental_status is a caller-assigned flag (paper: GCS <15).
magent does not read imaging. pleural_effusion is assigned by the caller.
BUN >25 mg/dL and age >60 are strict inequalities: BUN 25.0 and age 60 do not score.
Score only. magent does not emit mortality percentages.

Formula

BISAP = (bun_mg_dl>25) + impaired_mental_status + sirs + (age>60) + pleural_effusion; each 1 if present; max 5

Citation

Title: The early prediction of mortality in acute pancreatitis: a large population-based study
Authors: Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA
Source: Gut. 2008;57(12):1698-1703
DOI: 10.1136/gut.2008.150862

Worked example

All criteria absent

Given: age=50bun_mg_dl=20impaired_mental_status=falsepleural_effusion=falsesirs=false

BUN 20 is not >25 → 0; mental status false → 0; SIRS false → 0; age 50 is not >60 → 0; pleural effusion false → 0
Score = 0 (max 5)

All five criteria present

Given: age=61bun_mg_dl=26impaired_mental_status=truepleural_effusion=truesirs=true

BUN 26 > 25 → 1; mental status true → 1; SIRS true → 1; age 61 > 60 → 1; pleural effusion true → 1
Score = 5 (max 5)

Also searched as

BISAP score
Bedside Index of Severity in Acute Pancreatitis
Wu BISAP
acute pancreatitis BISAP
BISAP pancreatitis
BUN SIRS age pleural effusion

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/bisap?age=50&bun_mg_dl=20&impaired_mental_status=false&sirs=false&pleural_effusion=false

Full URL: https://api.magentlab.com/api/calc/bisap?age=50&bun_mg_dl=20&impaired_mental_status=false&sirs=false&pleural_effusion=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/bisap?age=50&bun_mg_dl=20&impaired_mental_status=false&sirs=false&pleural_effusion=false"

Parameters

Name	Type	Required	Description
`age`	integer	required	Age in years (18-120). Scores 1 when age >60; 60 does not score.
`bun_mg_dl`	number	required	Blood urea nitrogen in mg/dL (1-200). Scores 1 when >25; 25.0 does not score.
`impaired_mental_status`	boolean	required	Impaired mental status as assigned by the caller (paper: GCS <15). true or false. magent does not take GCS or assign mental status. 1 point if true.
`sirs`	boolean	required	SIRS present as assigned by the caller. true or false. magent does not recompute Bone SIRS from vitals. 1 point if true.
`pleural_effusion`	boolean	required	Pleural effusion as assigned by the caller from imaging. true or false. magent does not read imaging. 1 point if true.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/bisap Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "50",
      "bun_mg_dl": "20",
      "impaired_mental_status": "false",
      "pleural_effusion": "false",
      "sirs": "false"
    },
    {
      "age": "50",
      "bun_mg_dl": "20",
      "impaired_mental_status": "false",
      "pleural_effusion": "false",
      "sirs": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/bisap",
  "items": [
    {
      "components": [
        {
          "value": 20.0,
          "factor": "bun_gt_25",
          "points": 0,
          "present": false
        },
        {
          "factor": "impaired_mental_status",
          "points": 0,
          "present": false
        },
        {
          "factor": "sirs",
          "points": 0,
          "present": false
        },
        {
          "value": 50,
          "factor": "age_gt_60",
          "points": 0,
          "present": false
        },
        {
          "factor": "pleural_effusion",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA",
        "doi": "10.1136/gut.2008.150862",
        "id": "wu-2008",
        "source": "Gut. 2008;57(12):1698-1703",
        "title": "The early prediction of mortality in acute pancreatitis: a large population-based study"
      },
      "formula": "bisap",
      "formula_expression": "BISAP = (bun_mg_dl>25) + impaired_mental_status + sirs + (age>60) + pleural_effusion; each 1 if present; max 5",
      "age_years": 50,
      "max_score": 5,
      "score": 0,
      "bun_mg_dl": 20.0
    },
    {
      "components": [
        {
          "value": 20.0,
          "factor": "bun_gt_25",
          "points": 0,
          "present": false
        },
        {
          "factor": "impaired_mental_status",
          "points": 0,
          "present": false
        },
        {
          "factor": "sirs",
          "points": 0,
          "present": false
        },
        {
          "value": 50,
          "factor": "age_gt_60",
          "points": 0,
          "present": false
        },
        {
          "factor": "pleural_effusion",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA",
        "doi": "10.1136/gut.2008.150862",
        "id": "wu-2008",
        "source": "Gut. 2008;57(12):1698-1703",
        "title": "The early prediction of mortality in acute pancreatitis: a large population-based study"
      },
      "formula": "bisap",
      "formula_expression": "BISAP = (bun_mg_dl>25) + impaired_mental_status + sirs + (age>60) + pleural_effusion; each 1 if present; max 5",
      "age_years": 50,
      "max_score": 5,
      "score": 0,
      "bun_mg_dl": 20.0
    }
  ]
}

Response

Field	Type	Description
`formula`	string	bisap
`formula_expression`	string	Exact expression used
`score`	integer	Total points 0-5
`max_score`	integer	Always 5
`age_years`	integer	Age used for the >60 criterion
`bun_mg_dl`	number	BUN used in mg/dL
`components`	array	Per-criterion points
`citation`	object	Wu 2008 citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "components": [
    {
      "value": 20.0,
      "factor": "bun_gt_25",
      "points": 0,
      "present": false
    },
    {
      "factor": "impaired_mental_status",
      "points": 0,
      "present": false
    },
    {
      "factor": "sirs",
      "points": 0,
      "present": false
    },
    {
      "value": 50,
      "factor": "age_gt_60",
      "points": 0,
      "present": false
    },
    {
      "factor": "pleural_effusion",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA",
    "doi": "10.1136/gut.2008.150862",
    "id": "wu-2008",
    "source": "Gut. 2008;57(12):1698-1703",
    "title": "The early prediction of mortality in acute pancreatitis: a large population-based study"
  },
  "formula": "bisap",
  "formula_expression": "BISAP = (bun_mg_dl>25) + impaired_mental_status + sirs + (age>60) + pleural_effusion; each 1 if present; max 5",
  "age_years": 50,
  "max_score": 5,
  "score": 0,
  "bun_mg_dl": 20.0
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_age`	age must be an integer from 18 to 120 Returned before settlement; you are not charged.
400	`invalid_bun`	bun_mg_dl must be a number from 1 to 200. Returned before settlement; you are not charged.
400	`invalid_flag`	boolean clinical flags must be true or false Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

SIRS — Compute the Bone 1992 ACCP/SCCM SIRS criteria from temperature, heart rate, respiratory rate, and WBC, with optional PaCO2 and band percent.

Payment

Required query parameters must be present and valid. Invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

Invalid query parameters return HTTP 400 before settlement. You are not charged.
Settlement finishes before the tool executes (paymentFlow upfront). Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.