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CLIF-C ACLF

Compute the Jalan 2014 CLIF-C ACLF score from a caller-assigned CLIF-C OF (integer 6-18), age, and white-cell count in 10^9/L. magent does not score the six organs.

LIVE $0.005 USDC GET /api/calc/clif_c_aclf

Markdown: /docs/clif-c-aclf.md · Canonical: https://magentlab.com/docs/clif-c-aclf

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Jalan 2014 CLIF-C ACLF score from a caller-assigned CLIF-C OF (integer 6-18), age, and white-cell count in 10^9/L. magent does not score the six organs.

When to use

When an agent needs published Jalan 2014 CLIF-C ACLF (CANONIC) arithmetic from a caller-assigned CLIF-C OF, age, and WBC and must not invent MELD, Child-Pugh, or organ-failure subscores.

When not to use

  • Not a medical device. Not a diagnosis and not a transplant listing protocol.
  • Caller supplies clif_c_of (integer 6-18). magent does not compute CLIF-C OF from organs and does not score CLIF-SOFA.
  • Not MELD, not MELD-Na, and not Child-Pugh. This is the Jalan 2014 CLIF-C ACLF equation only.

Formula

clif_c_aclf = 10 * (0.33 * clif_c_of + 0.04 * age + 0.63 * ln(wbc_10e9_l) - 2); caller-assigned CLIF-C OF 6-18; round 1 decimal then clamp 0-100 (Jalan 2014 CANONIC)

Citation

Title
Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure.
Authors
Jalan R, Saliba F, Pavesi M, et al.
Source
J Hepatol. 2014;61(5):1038-1047
DOI
10.1016/j.jhep.2014.06.012

Worked example

CLIF-C OF 6, age 50, WBC 5

Given: age=50clif_c_of=6wbc_10e9_l=5

  1. Caller-assigned CLIF-C OF = 6 (magent does not score organs)
  2. CLIF-C ACLF = 10 × (0.33×6 + 0.04×50 + 0.63×ln(5) − 2)
  3. Round 1 decimal then clamp 0-100 → 29.9

Also searched as

  • CLIF-C ACLF
  • CLIF Consortium ACLF
  • acute-on-chronic liver failure score
  • Jalan 2014 ACLF
  • CANONIC ACLF
  • CLIF-C OF ACLF score

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/clif_c_aclf?clif_c_of=6&age=50&wbc_10e9_l=5

Full URL: https://api.magentlab.com/api/calc/clif_c_aclf?clif_c_of=6&age=50&wbc_10e9_l=5

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/clif_c_aclf?clif_c_of=6&age=50&wbc_10e9_l=5"

Parameters

Name Type Required Description
clif_c_of integer required Caller-assigned CLIF-C organ-failure score, integer 6-18 (Jalan 2014). magent does not score the six organs or compute CLIF-C OF.
age integer required Age in years (18-120).
wbc_10e9_l number required White-cell count in 10^9/L (0.1-200). Natural log in the equation.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/clif_c_aclf Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "50",
      "clif_c_of": "6",
      "wbc_10e9_l": "5"
    },
    {
      "age": "50",
      "clif_c_of": "6",
      "wbc_10e9_l": "5"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/clif_c_aclf",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Jalan R, Saliba F, Pavesi M, et al.",
        "doi": "10.1016/j.jhep.2014.06.012",
        "id": "jalan-2014",
        "pmid": "24950482",
        "source": "J Hepatol. 2014;61(5):1038-1047",
        "title": "Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure."
      },
      "formula": "clif_c_aclf",
      "formula_expression": "clif_c_aclf = 10 * (0.33 * clif_c_of + 0.04 * age + 0.63 * ln(wbc_10e9_l) - 2); caller-assigned CLIF-C OF 6-18; round 1 decimal then clamp 0-100 (Jalan 2014 CANONIC)",
      "age_years": 50,
      "wbc_10e9_l": 5.0,
      "clif_c_aclf": 29.9,
      "clif_c_of": 6
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Jalan R, Saliba F, Pavesi M, et al.",
        "doi": "10.1016/j.jhep.2014.06.012",
        "id": "jalan-2014",
        "pmid": "24950482",
        "source": "J Hepatol. 2014;61(5):1038-1047",
        "title": "Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure."
      },
      "formula": "clif_c_aclf",
      "formula_expression": "clif_c_aclf = 10 * (0.33 * clif_c_of + 0.04 * age + 0.63 * ln(wbc_10e9_l) - 2); caller-assigned CLIF-C OF 6-18; round 1 decimal then clamp 0-100 (Jalan 2014 CANONIC)",
      "age_years": 50,
      "wbc_10e9_l": 5.0,
      "clif_c_aclf": 29.9,
      "clif_c_of": 6
    }
  ]
}

Response

Field Type Description
formula string clif_c_aclf
formula_expression string Exact Jalan 2014 CLIF-C ACLF expression, including 1-decimal round and 0-100 clamp
clif_c_of integer Caller-assigned CLIF-C OF used (6-18). Not scored from organs.
age_years integer Age in years used
wbc_10e9_l number White-cell count in 10^9/L
clif_c_aclf number CLIF-C ACLF score, 1 decimal, clamped 0-100. Not MELD or Child-Pugh.
citation object Jalan J Hepatol 2014 citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Jalan R, Saliba F, Pavesi M, et al.",
    "doi": "10.1016/j.jhep.2014.06.012",
    "id": "jalan-2014",
    "pmid": "24950482",
    "source": "J Hepatol. 2014;61(5):1038-1047",
    "title": "Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure."
  },
  "formula": "clif_c_aclf",
  "formula_expression": "clif_c_aclf = 10 * (0.33 * clif_c_of + 0.04 * age + 0.63 * ln(wbc_10e9_l) - 2); caller-assigned CLIF-C OF 6-18; round 1 decimal then clamp 0-100 (Jalan 2014 CANONIC)",
  "age_years": 50,
  "wbc_10e9_l": 5.0,
  "clif_c_aclf": 29.9,
  "clif_c_of": 6
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_clif_aclf clif_c_of must be an integer 6-18 and wbc_10e9_l a number from 0.1 to 200 (Jalan 2014 CLIF-C ACLF; caller-assigned CLIF-C OF). Returned before settlement; you are not charged.
400 invalid_age age must be an integer from 18 to 120 Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • MELD — Compute the Kamath 2001 model for end-stage liver disease (MELD) integer from creatinine, bilirubin, INR, and cholestatic or alcoholic etiology.
  • Child–Pugh — Compute the Child–Turcotte–Pugh cirrhosis severity score from bilirubin, albumin, INR, encephalopathy, and ascites.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.