Hematology · LIVE

EUTOS score

Compute the Hasford 2011 EUTOS score for baseline untreated chronic myeloid leukemia from spleen size below the costal margin and peripheral-blood basophil percent, with the paper’s two groups (low ≤87, high >87).

LIVE $0.005 USDC GET /api/calc/eutos

Markdown: /docs/eutos.md · Canonical: https://magentlab.com/docs/eutos

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the Hasford 2011 EUTOS score for baseline untreated chronic myeloid leukemia from spleen size below the costal margin and peripheral-blood basophil percent, with the paper’s two groups (low ≤87, high >87).

When to use

When an agent needs the published Hasford 2011 EUTOS score and must not invent later CML scores, diagnose CML, or choose TKI therapy.

When not to use

• Not a medical device. magent does not diagnose CML.
• Hasford 2011 applies to baseline untreated chronic myeloid leukemia (CML) only.
• Does not choose TKI therapy or any other treatment.

Formula

eutos_score = 4 * spleen_cm + 7 * basophils_percent

Citation

Title

Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score

Authors

Hasford J, Baccarani M, Hoffmann V, Guilhot J, Saussele S, Rosti G, Guilhot F, Porkka K, Ossenkoppele G, Lindoerfer D, Simonsson B, Pfirrmann M, Hehlmann R

Source

Blood. 2011;118(3):686-692

DOI

10.1182/blood-2010-12-319038

Worked example

Also searched as

• EUTOS score
• EUTOS CML
• Hasford 2011
• European Treatment and Outcome Study score
• CML EUTOS
• chronic myeloid leukemia EUTOS
• EUTOS prognostic score
• Hasford EUTOS

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/eutos?spleen_cm=5&basophils_percent=2

Full URL: https://api.magentlab.com/api/calc/eutos?spleen_cm=5&basophils_percent=2

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/eutos?spleen_cm=5&basophils_percent=2"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/eutos Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "basophils_percent": "2",
      "spleen_cm": "5"
    },
    {
      "basophils_percent": "2",
      "spleen_cm": "5"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/eutos",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Hasford J, Baccarani M, Hoffmann V, Guilhot J, Saussele S, Rosti G, Guilhot F, Porkka K, Ossenkoppele G, Lindoerfer D, Simonsson B, Pfirrmann M, Hehlmann R",
        "doi": "10.1182/blood-2010-12-319038",
        "id": "hasford-2011",
        "pmid": "21536864",
        "source": "Blood. 2011;118(3):686-692",
        "title": "Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score"
      },
      "formula": "eutos",
      "formula_expression": "eutos_score = 4 * spleen_cm + 7 * basophils_percent",
      "basophils_percent": 2.0,
      "eutos_band": "low",
      "eutos_score": 34.0,
      "spleen_cm": 5.0
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Hasford J, Baccarani M, Hoffmann V, Guilhot J, Saussele S, Rosti G, Guilhot F, Porkka K, Ossenkoppele G, Lindoerfer D, Simonsson B, Pfirrmann M, Hehlmann R",
        "doi": "10.1182/blood-2010-12-319038",
        "id": "hasford-2011",
        "pmid": "21536864",
        "source": "Blood. 2011;118(3):686-692",
        "title": "Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score"
      },
      "formula": "eutos",
      "formula_expression": "eutos_score = 4 * spleen_cm + 7 * basophils_percent",
      "basophils_percent": 2.0,
      "eutos_band": "low",
      "eutos_score": 34.0,
      "spleen_cm": 5.0
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Hasford J, Baccarani M, Hoffmann V, Guilhot J, Saussele S, Rosti G, Guilhot F, Porkka K, Ossenkoppele G, Lindoerfer D, Simonsson B, Pfirrmann M, Hehlmann R",
    "doi": "10.1182/blood-2010-12-319038",
    "id": "hasford-2011",
    "pmid": "21536864",
    "source": "Blood. 2011;118(3):686-692",
    "title": "Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score"
  },
  "formula": "eutos",
  "formula_expression": "eutos_score = 4 * spleen_cm + 7 * basophils_percent",
  "basophils_percent": 2.0,
  "eutos_band": "low",
  "eutos_score": 34.0,
  "spleen_cm": 5.0
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• Sokal index — Compute the Sokal 1984 relative-risk index for newly diagnosed untreated chronic granulocytic leukemia from age, spleen size below the costal margin, platelet count, and percent circulating blasts, with the paper’s three groups.
• ANC — Compute absolute neutrophil count from WBC and neutrophil plus band percents, plus a Bodey 1966 granulocyte band.
• NLR — Compute the Zahorec 2001 neutrophil-to-lymphocyte ratio from relative neutrophil and lymphocyte percents.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.