MAGENT

Hematology · LIVE

FLIPI (Solal-Céligny)

FLIPI

Sum the Solal-Céligny 2004 FLIPI adverse factors for follicular lymphoma and return low (0–1), intermediate (2), or high (≥3).

LIVE $0.005 USDC GET /api/calc/flipi

Markdown: /docs/flipi.md · Canonical: https://magentlab.com/docs/flipi

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Sum the Solal-Céligny 2004 FLIPI adverse factors for follicular lymphoma and return low (0–1), intermediate (2), or high (≥3).

When to use

When an agent needs the published FLIPI 2004 point total and class and must not invent a follicular-lymphoma diagnosis or treatment choice, and must not substitute FLIPI-2.

When not to use

  • Not a medical device and not a follicular-lymphoma diagnosis or treatment choice. magent does not examine the patient.
  • This is FLIPI 2004 (Solal-Céligny), not FLIPI-2.
  • magent does not stage lymphoma, assay hemoglobin, count nodal sites, or measure LDH. All five inputs are caller-assigned flags.

Formula

FLIPI = age_gt_60 1 + stage_iii_iv 1 + hemoglobin_lt_120_g_l 1 + nodal_sites_gt_4 1 + ldh_above_uln 1; Solal-Céligny 2004; max 5; low 0-1, intermediate 2, high ≥3

Citation

Title
Follicular lymphoma international prognostic index
Authors
Solal-Céligny P, Roy P, Colombat P, White J, Armitage JO, Arranz-Saez R, Au WY, Bellei M, Brice P, Caballero D, Coiffier B, Conde-Garcia E, Doyen C, Federico M, Fisher RI, Garcia-Conde JF, Gisselbrecht C, Haioun C, LeBlanc M, Lister AT, Lopez-Guillermo A, McLaughlin P, Milpied N, Morel P, Mounier N, Proctor SJ, Rohatiner A, Smith P, Soubeyran P, Tilly H, Vitolo U, Zinzani PL, Zucca E, Montserrat E
Source
Blood. 2004;104(5):1258-1265
DOI
10.1182/blood-2003-12-4434

Worked example

All flags false

Given: age_gt_60=falsehemoglobin_lt_120_g_l=falseldh_above_uln=falsenodal_sites_gt_4=falsestage_iii_iv=false

  1. All five caller-assigned flags false → 0
  2. Score = 0 (max 5); flipi_band = low

Age >60, Ann Arbor III–IV, and hemoglobin <120 g/L

Given: age_gt_60=truehemoglobin_lt_120_g_l=trueldh_above_uln=falsenodal_sites_gt_4=falsestage_iii_iv=true

  1. age_gt_60 → 1; stage_iii_iv → 1; hemoglobin_lt_120_g_l → 1; remaining flags 0
  2. Score = 3 (max 5); flipi_band = high (≥3)

Also searched as

  • FLIPI
  • Follicular lymphoma international prognostic index
  • Solal-Céligny FLIPI
  • FLIPI 2004
  • follicular lymphoma prognostic index
  • Ann Arbor FLIPI
  • FLIPI score

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/flipi?age_gt_60=false&stage_iii_iv=false&hemoglobin_lt_120_g_l=false&nodal_sites_gt_4=false&ldh_above_uln=false

Full URL: https://api.magentlab.com/api/calc/flipi?age_gt_60=false&stage_iii_iv=false&hemoglobin_lt_120_g_l=false&nodal_sites_gt_4=false&ldh_above_uln=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge. 

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/flipi?age_gt_60=false&stage_iii_iv=false&hemoglobin_lt_120_g_l=false&nodal_sites_gt_4=false&ldh_above_uln=false"

Parameters

Name Type Required Description
age_gt_60 boolean required Age >60 years as assigned by the caller (Solal-Céligny 2004). true scores 1. magent does not assign age.
stage_iii_iv boolean required Ann Arbor stage III–IV as assigned by the caller (Solal-Céligny 2004). true scores 1. magent does not stage lymphoma.
hemoglobin_lt_120_g_l boolean required Hemoglobin <120 g/L as assigned by the caller (Solal-Céligny 2004). true scores 1. magent does not assay hemoglobin.
nodal_sites_gt_4 boolean required Nodal areas >4 as assigned by the caller (Solal-Céligny 2004). true scores 1. magent does not count nodal sites.
ldh_above_uln boolean required Serum LDH above the upper limit of normal as assigned by the caller (Solal-Céligny 2004). true scores 1. magent does not measure LDH.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/flipi Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age_gt_60": "false",
      "hemoglobin_lt_120_g_l": "false",
      "ldh_above_uln": "false",
      "nodal_sites_gt_4": "false",
      "stage_iii_iv": "false"
    },
    {
      "age_gt_60": "false",
      "hemoglobin_lt_120_g_l": "false",
      "ldh_above_uln": "false",
      "nodal_sites_gt_4": "false",
      "stage_iii_iv": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/flipi",
  "items": [
    {
      "components": [
        {
          "factor": "age_gt_60",
          "points": 0,
          "present": false
        },
        {
          "factor": "stage_iii_iv",
          "points": 0,
          "present": false
        },
        {
          "factor": "hemoglobin_lt_120_g_l",
          "points": 0,
          "present": false
        },
        {
          "factor": "nodal_sites_gt_4",
          "points": 0,
          "present": false
        },
        {
          "factor": "ldh_above_uln",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Solal-Céligny P, Roy P, Colombat P, White J, Armitage JO, Arranz-Saez R, Au WY, Bellei M, Brice P, Caballero D, Coiffier B, Conde-Garcia E, Doyen C, Federico M, Fisher RI, Garcia-Conde JF, Gisselbrecht C, Haioun C, LeBlanc M, Lister AT, Lopez-Guillermo A, McLaughlin P, Milpied N, Morel P, Mounier N, Proctor SJ, Rohatiner A, Smith P, Soubeyran P, Tilly H, Vitolo U, Zinzani PL, Zucca E, Montserrat E",
        "doi": "10.1182/blood-2003-12-4434",
        "id": "solal-celigny-2004",
        "pmid": "15126323",
        "source": "Blood. 2004;104(5):1258-1265",
        "title": "Follicular lymphoma international prognostic index"
      },
      "formula": "flipi",
      "formula_expression": "FLIPI = age_gt_60 1 + stage_iii_iv 1 + hemoglobin_lt_120_g_l 1 + nodal_sites_gt_4 1 + ldh_above_uln 1; Solal-Céligny 2004; max 5; low 0-1, intermediate 2, high ≥3",
      "max_score": 5,
      "score": 0,
      "flipi_band": "low"
    },
    {
      "components": [
        {
          "factor": "age_gt_60",
          "points": 0,
          "present": false
        },
        {
          "factor": "stage_iii_iv",
          "points": 0,
          "present": false
        },
        {
          "factor": "hemoglobin_lt_120_g_l",
          "points": 0,
          "present": false
        },
        {
          "factor": "nodal_sites_gt_4",
          "points": 0,
          "present": false
        },
        {
          "factor": "ldh_above_uln",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Solal-Céligny P, Roy P, Colombat P, White J, Armitage JO, Arranz-Saez R, Au WY, Bellei M, Brice P, Caballero D, Coiffier B, Conde-Garcia E, Doyen C, Federico M, Fisher RI, Garcia-Conde JF, Gisselbrecht C, Haioun C, LeBlanc M, Lister AT, Lopez-Guillermo A, McLaughlin P, Milpied N, Morel P, Mounier N, Proctor SJ, Rohatiner A, Smith P, Soubeyran P, Tilly H, Vitolo U, Zinzani PL, Zucca E, Montserrat E",
        "doi": "10.1182/blood-2003-12-4434",
        "id": "solal-celigny-2004",
        "pmid": "15126323",
        "source": "Blood. 2004;104(5):1258-1265",
        "title": "Follicular lymphoma international prognostic index"
      },
      "formula": "flipi",
      "formula_expression": "FLIPI = age_gt_60 1 + stage_iii_iv 1 + hemoglobin_lt_120_g_l 1 + nodal_sites_gt_4 1 + ldh_above_uln 1; Solal-Céligny 2004; max 5; low 0-1, intermediate 2, high ≥3",
      "max_score": 5,
      "score": 0,
      "flipi_band": "low"
    }
  ]
}

Response

Field Type Description
formula string flipi
formula_expression string Exact expression used
score integer FLIPI points 0-5
max_score integer Always 5
flipi_band string low when score is 0-1, intermediate when 2, high when ≥3 (Solal-Céligny 2004). Not a follicular-lymphoma diagnosis or treatment choice. FLIPI 2004, not FLIPI-2.
components array Per-factor points
citation object Solal-Céligny 2004 Blood citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup. 

{
  "components": [
    {
      "factor": "age_gt_60",
      "points": 0,
      "present": false
    },
    {
      "factor": "stage_iii_iv",
      "points": 0,
      "present": false
    },
    {
      "factor": "hemoglobin_lt_120_g_l",
      "points": 0,
      "present": false
    },
    {
      "factor": "nodal_sites_gt_4",
      "points": 0,
      "present": false
    },
    {
      "factor": "ldh_above_uln",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Solal-Céligny P, Roy P, Colombat P, White J, Armitage JO, Arranz-Saez R, Au WY, Bellei M, Brice P, Caballero D, Coiffier B, Conde-Garcia E, Doyen C, Federico M, Fisher RI, Garcia-Conde JF, Gisselbrecht C, Haioun C, LeBlanc M, Lister AT, Lopez-Guillermo A, McLaughlin P, Milpied N, Morel P, Mounier N, Proctor SJ, Rohatiner A, Smith P, Soubeyran P, Tilly H, Vitolo U, Zinzani PL, Zucca E, Montserrat E",
    "doi": "10.1182/blood-2003-12-4434",
    "id": "solal-celigny-2004",
    "pmid": "15126323",
    "source": "Blood. 2004;104(5):1258-1265",
    "title": "Follicular lymphoma international prognostic index"
  },
  "formula": "flipi",
  "formula_expression": "FLIPI = age_gt_60 1 + stage_iii_iv 1 + hemoglobin_lt_120_g_l 1 + nodal_sites_gt_4 1 + ldh_above_uln 1; Solal-Céligny 2004; max 5; low 0-1, intermediate 2, high ≥3",
  "max_score": 5,
  "score": 0,
  "flipi_band": "low"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_flag boolean clinical flags must be true or false Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • ANC — Compute absolute neutrophil count from WBC and neutrophil plus band percents, plus a Bodey 1966 granulocyte band.
  • NLR — Compute the Zahorec 2001 neutrophil-to-lymphocyte ratio from relative neutrophil and lymphocyte percents.
  • ISTH overt DIC — Sum the four Taylor 2001 ISTH SSC overt DIC laboratory items (platelets, fibrin-related marker, PT prolongation, fibrinogen) and return the published <5 / >=5 band.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.