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Rome IV centrally mediated abdominal pain syndrome

Rome IV CAPS

Apply the Keefer 2016 Rome IV centrally mediated abdominal pain syndrome (CAPS / D1) diagnostic criteria and return whether the published CAPS box holds (rome_iv_caps).

LIVE $0.005 USDC GET /api/calc/rome_iv_caps

Markdown: /docs/rome-iv-caps.md · Canonical: https://magentlab.com/docs/rome-iv-caps

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Keefer 2016 Rome IV centrally mediated abdominal pain syndrome (CAPS / D1) diagnostic criteria and return whether the published CAPS box holds (rome_iv_caps).

When to use

When an agent already has the seven caller-assigned Keefer 2016 Rome IV CAPS flags and needs whether the published CAPS box holds. magent does not examine the patient or judge feigning beyond the caller flag.

When not to use

  • Not a medical device.
  • Not a diagnosis. magent does not diagnose centrally mediated abdominal pain syndrome.
  • The caller assigns the seven flags. magent does not examine the patient or judge feigning beyond the caller flag.
  • This tool is Keefer 2016 Rome IV CAPS (D1) only. Psychosocial comorbidity is copy-only and is not parsed. Not Rome IV IBS (Mearin 2016). Not narcotic bowel syndrome (NBS).

Formula

rome_iv_caps iff continuous_or_nearly_continuous_abdominal_pain and no_or_only_occasional_relationship_with_physiological_events and pain_limits_daily_functioning and pain_not_feigned and not_explained_by_another_gi_or_medical_condition and fulfilled_last_3_months and onset_at_least_6_months (Keefer 2016 Rome IV CAPS / D1)

Citation

Title
Centrally Mediated Disorders of Gastrointestinal Pain
Authors
Keefer L, Drossman DA, Guthrie E, Simrén M, Tillisch K, Olden K, Whorwell PJ
Source
Gastroenterology. 2016;150(6):1408-1419
DOI
10.1053/j.gastro.2016.02.034

Worked example

All seven required flags

Given: continuous_or_nearly_continuous_abdominal_pain=truefulfilled_last_3_months=trueno_or_only_occasional_relationship_with_physiological_events=truenot_explained_by_another_gi_or_medical_condition=trueonset_at_least_6_months=truepain_limits_daily_functioning=truepain_not_feigned=true

  1. Continuous or nearly continuous abdominal pain is true
  2. No or only occasional relationship with eating, defecation, or menses is true
  3. Pain limits daily functioning is true
  4. Pain is not feigned
  5. Pain is not explained by another GI or medical condition
  6. Criteria fulfilled for the last 3 months and onset at least 6 months prior are true
  7. rome_iv_caps is true

Six required flags without 6-month onset

Given: continuous_or_nearly_continuous_abdominal_pain=truefulfilled_last_3_months=trueno_or_only_occasional_relationship_with_physiological_events=truenot_explained_by_another_gi_or_medical_condition=trueonset_at_least_6_months=falsepain_limits_daily_functioning=truepain_not_feigned=true

  1. Six required flags hold
  2. Onset at least 6 months prior is false
  3. rome_iv_caps is false

Also searched as

  • Rome IV CAPS
  • Rome IV centrally mediated abdominal pain syndrome
  • Keefer 2016 CAPS
  • centrally mediated abdominal pain
  • functional abdominal pain syndrome
  • Rome IV FAPS
  • Rome IV D1 CAPS
  • CAPS diagnostic criteria

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/rome_iv_caps?continuous_or_nearly_continuous_abdominal_pain=true&no_or_only_occasional_relationship_with_physiological_events=true&pain_limits_daily_functioning=true&pain_not_feigned=true&not_explained_by_another_gi_or_medical_condition=true&fulfilled_last_3_months=true&onset_at_least_6_months=true

Full URL: https://api.magentlab.com/api/calc/rome_iv_caps?continuous_or_nearly_continuous_abdominal_pain=true&no_or_only_occasional_relationship_with_physiological_events=true&pain_limits_daily_functioning=true&pain_not_feigned=true&not_explained_by_another_gi_or_medical_condition=true&fulfilled_last_3_months=true&onset_at_least_6_months=true

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge. 

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/rome_iv_caps?continuous_or_nearly_continuous_abdominal_pain=true&no_or_only_occasional_relationship_with_physiological_events=true&pain_limits_daily_functioning=true&pain_not_feigned=true&not_explained_by_another_gi_or_medical_condition=true&fulfilled_last_3_months=true&onset_at_least_6_months=true"

Parameters

Name Type Required Description
continuous_or_nearly_continuous_abdominal_pain boolean required Continuous or nearly continuous abdominal pain, as assigned (Keefer 2016 Rome IV CAPS / D1). true or false as assigned by the caller. magent does not examine the patient.
no_or_only_occasional_relationship_with_physiological_events boolean required No or only occasional relationship of pain with physiological events (eating, defecation, or menses), as assigned (Keefer 2016). true or false as assigned by the caller. magent does not examine the patient.
pain_limits_daily_functioning boolean required Pain limits some aspect of daily functioning, as assigned (Keefer 2016). true or false as assigned by the caller. magent does not examine the patient.
pain_not_feigned boolean required The pain is not feigned, as assigned by the caller (Keefer 2016). true or false as assigned by the caller. magent does not judge feigning beyond this flag.
not_explained_by_another_gi_or_medical_condition boolean required Pain is not explained by another structural or functional gastrointestinal disorder or other medical condition, as assigned (Keefer 2016). true or false as assigned by the caller. magent does not examine the patient.
fulfilled_last_3_months boolean required Criteria fulfilled for the last 3 months, as assigned (Keefer 2016). true or false as assigned by the caller. magent does not take a history.
onset_at_least_6_months boolean required Symptom onset at least 6 months prior to diagnosis, as assigned (Keefer 2016). true or false as assigned by the caller. magent does not take a history.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/rome_iv_caps Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "continuous_or_nearly_continuous_abdominal_pain": "true",
      "fulfilled_last_3_months": "true",
      "no_or_only_occasional_relationship_with_physiological_events": "true",
      "not_explained_by_another_gi_or_medical_condition": "true",
      "onset_at_least_6_months": "true",
      "pain_limits_daily_functioning": "true",
      "pain_not_feigned": "true"
    },
    {
      "continuous_or_nearly_continuous_abdominal_pain": "true",
      "fulfilled_last_3_months": "true",
      "no_or_only_occasional_relationship_with_physiological_events": "true",
      "not_explained_by_another_gi_or_medical_condition": "true",
      "onset_at_least_6_months": "true",
      "pain_limits_daily_functioning": "true",
      "pain_not_feigned": "true"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/rome_iv_caps",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Keefer L, Drossman DA, Guthrie E, Simrén M, Tillisch K, Olden K, Whorwell PJ",
        "doi": "10.1053/j.gastro.2016.02.034",
        "id": "keefer-2016",
        "pmid": "27144628",
        "source": "Gastroenterology. 2016;150(6):1408-1419",
        "title": "Centrally Mediated Disorders of Gastrointestinal Pain"
      },
      "formula": "rome_iv_caps",
      "formula_expression": "rome_iv_caps iff continuous_or_nearly_continuous_abdominal_pain and no_or_only_occasional_relationship_with_physiological_events and pain_limits_daily_functioning and pain_not_feigned and not_explained_by_another_gi_or_medical_condition and fulfilled_last_3_months and onset_at_least_6_months (Keefer 2016 Rome IV CAPS / D1)",
      "criteria": [
        {
          "factor": "continuous_or_nearly_continuous_abdominal_pain",
          "met": true
        },
        {
          "factor": "no_or_only_occasional_relationship_with_physiological_events",
          "met": true
        },
        {
          "factor": "pain_limits_daily_functioning",
          "met": true
        },
        {
          "factor": "pain_not_feigned",
          "met": true
        },
        {
          "factor": "not_explained_by_another_gi_or_medical_condition",
          "met": true
        },
        {
          "factor": "fulfilled_last_3_months",
          "met": true
        },
        {
          "factor": "onset_at_least_6_months",
          "met": true
        }
      ],
      "rome_iv_caps": true
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Keefer L, Drossman DA, Guthrie E, Simrén M, Tillisch K, Olden K, Whorwell PJ",
        "doi": "10.1053/j.gastro.2016.02.034",
        "id": "keefer-2016",
        "pmid": "27144628",
        "source": "Gastroenterology. 2016;150(6):1408-1419",
        "title": "Centrally Mediated Disorders of Gastrointestinal Pain"
      },
      "formula": "rome_iv_caps",
      "formula_expression": "rome_iv_caps iff continuous_or_nearly_continuous_abdominal_pain and no_or_only_occasional_relationship_with_physiological_events and pain_limits_daily_functioning and pain_not_feigned and not_explained_by_another_gi_or_medical_condition and fulfilled_last_3_months and onset_at_least_6_months (Keefer 2016 Rome IV CAPS / D1)",
      "criteria": [
        {
          "factor": "continuous_or_nearly_continuous_abdominal_pain",
          "met": true
        },
        {
          "factor": "no_or_only_occasional_relationship_with_physiological_events",
          "met": true
        },
        {
          "factor": "pain_limits_daily_functioning",
          "met": true
        },
        {
          "factor": "pain_not_feigned",
          "met": true
        },
        {
          "factor": "not_explained_by_another_gi_or_medical_condition",
          "met": true
        },
        {
          "factor": "fulfilled_last_3_months",
          "met": true
        },
        {
          "factor": "onset_at_least_6_months",
          "met": true
        }
      ],
      "rome_iv_caps": true
    }
  ]
}

Response

Field Type Description
formula string rome_iv_caps
formula_expression string Keefer 2016 Rome IV CAPS / D1: continuous or nearly continuous abdominal pain, no or only occasional relationship with eating, defecation, or menses, pain limits daily functioning, pain is not feigned, not explained by another GI or medical condition, last-3-months criteria, and 6-month onset
rome_iv_caps boolean true only when all seven required flags hold. Not a diagnosis.
criteria array Per-factor rows with factor and met for the seven required flags
citation object Keefer 2016 Gastroenterology citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup. 

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Keefer L, Drossman DA, Guthrie E, Simrén M, Tillisch K, Olden K, Whorwell PJ",
    "doi": "10.1053/j.gastro.2016.02.034",
    "id": "keefer-2016",
    "pmid": "27144628",
    "source": "Gastroenterology. 2016;150(6):1408-1419",
    "title": "Centrally Mediated Disorders of Gastrointestinal Pain"
  },
  "formula": "rome_iv_caps",
  "formula_expression": "rome_iv_caps iff continuous_or_nearly_continuous_abdominal_pain and no_or_only_occasional_relationship_with_physiological_events and pain_limits_daily_functioning and pain_not_feigned and not_explained_by_another_gi_or_medical_condition and fulfilled_last_3_months and onset_at_least_6_months (Keefer 2016 Rome IV CAPS / D1)",
  "criteria": [
    {
      "factor": "continuous_or_nearly_continuous_abdominal_pain",
      "met": true
    },
    {
      "factor": "no_or_only_occasional_relationship_with_physiological_events",
      "met": true
    },
    {
      "factor": "pain_limits_daily_functioning",
      "met": true
    },
    {
      "factor": "pain_not_feigned",
      "met": true
    },
    {
      "factor": "not_explained_by_another_gi_or_medical_condition",
      "met": true
    },
    {
      "factor": "fulfilled_last_3_months",
      "met": true
    },
    {
      "factor": "onset_at_least_6_months",
      "met": true
    }
  ],
  "rome_iv_caps": true
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_rome_iv_caps Rome IV CAPS needs the Keefer 2016 centrally mediated abdominal pain flags. Returned before settlement; you are not charged.
400 invalid_flag boolean clinical flags must be true or false Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • Rome IV IBS — Apply the Mearin 2016 Rome IV IBS diagnostic criteria and return supporting_features_met (0-3) and whether the published IBS box holds (rome_iv_ibs).
  • Rome IV FD — Apply the Stanghellini 2016 Rome IV B1 functional dyspepsia criteria and return whether PDS (B1a), EPS (B1b), and the published FD box hold (rome_iv_fd).

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.