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Rome IV cannabinoid hyperemesis

Rome IV CHS

Apply the Stanghellini 2016 Rome IV cannabinoid hyperemesis syndrome diagnostic criteria and return whether the published CHS box holds (rome_iv_chs) plus the supportive pathologic_bathing flag.

LIVE $0.005 USDC GET /api/calc/rome_iv_chs

Markdown: /docs/rome-iv-chs.md · Canonical: https://magentlab.com/docs/rome-iv-chs

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Stanghellini 2016 Rome IV cannabinoid hyperemesis syndrome diagnostic criteria and return whether the published CHS box holds (rome_iv_chs) plus the supportive pathologic_bathing flag.

When to use

When an agent already has the six caller-assigned Stanghellini 2016 Rome IV CHS flags and needs whether the published CHS box holds. magent does not take a cannabis history.

When not to use

  • Not a medical device.
  • Not a diagnosis. magent does not diagnose cannabinoid hyperemesis syndrome.
  • The caller assigns the six flags. magent does not examine the patient or take a cannabis history.
  • This tool is Stanghellini 2016 Rome IV cannabinoid hyperemesis syndrome only. Pathologic bathing is supportive and not required for rome_iv_chs. Not cyclic vomiting syndrome as the primary tool. Not Rome IV IBS (Mearin 2016). Not Rome IV functional dyspepsia.

Formula

rome_iv_chs iff stereotypical_episodic_vomiting and after_prolonged_excessive_cannabis and relief_with_sustained_cessation and fulfilled_last_3_months and onset_at_least_6_months; pathologic_bathing is supportive and not required (Stanghellini 2016 Rome IV cannabinoid hyperemesis syndrome)

Citation

Title
Gastroduodenal Disorders
Authors
Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, Talley NJ
Source
Gastroenterology. 2016;150(6):1380-1392
DOI
10.1053/j.gastro.2016.02.011

Worked example

Five required flags and pathologic bathing

Given: after_prolonged_excessive_cannabis=truefulfilled_last_3_months=trueonset_at_least_6_months=truepathologic_bathing=truerelief_with_sustained_cessation=truestereotypical_episodic_vomiting=true

  1. Stereotypical episodic vomiting resembling CVS is true
  2. Presentation after prolonged excessive cannabis use is true
  3. Relief with sustained cannabis cessation is true
  4. Criteria fulfilled for the last 3 months and onset at least 6 months prior are true
  5. Pathologic bathing is true (supportive, not required)
  6. rome_iv_chs is true

Five required flags without pathologic bathing

Given: after_prolonged_excessive_cannabis=truefulfilled_last_3_months=trueonset_at_least_6_months=truepathologic_bathing=falserelief_with_sustained_cessation=truestereotypical_episodic_vomiting=true

  1. All five required flags hold
  2. Pathologic bathing is false
  3. rome_iv_chs is true because bathing is supportive and not required

Also searched as

  • Rome IV CHS
  • Rome IV cannabinoid hyperemesis
  • cannabinoid hyperemesis syndrome
  • Stanghellini 2016 CHS
  • CHS diagnostic criteria
  • cannabinoid hyperemesis Rome IV
  • Rome IV cannabis vomiting
  • pathologic bathing CHS

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/rome_iv_chs?stereotypical_episodic_vomiting=true&after_prolonged_excessive_cannabis=true&relief_with_sustained_cessation=true&fulfilled_last_3_months=true&onset_at_least_6_months=true&pathologic_bathing=true

Full URL: https://api.magentlab.com/api/calc/rome_iv_chs?stereotypical_episodic_vomiting=true&after_prolonged_excessive_cannabis=true&relief_with_sustained_cessation=true&fulfilled_last_3_months=true&onset_at_least_6_months=true&pathologic_bathing=true

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/rome_iv_chs?stereotypical_episodic_vomiting=true&after_prolonged_excessive_cannabis=true&relief_with_sustained_cessation=true&fulfilled_last_3_months=true&onset_at_least_6_months=true&pathologic_bathing=true"

Parameters

Name Type Required Description
stereotypical_episodic_vomiting boolean required Stereotypical episodic vomiting resembling cyclic vomiting syndrome (CVS) in onset, duration, and frequency (Stanghellini 2016). true or false as assigned by the caller. magent does not examine the patient.
after_prolonged_excessive_cannabis boolean required Presentation after prolonged excessive cannabis use, as assigned (Stanghellini 2016). true or false as assigned by the caller. magent does not take a cannabis history.
relief_with_sustained_cessation boolean required Relief of vomiting episodes by sustained cessation of cannabis, as assigned (Stanghellini 2016). true or false as assigned by the caller. magent does not take a cannabis history.
fulfilled_last_3_months boolean required Criteria fulfilled for the last 3 months, as assigned (Stanghellini 2016). true or false as assigned by the caller. magent does not take a history.
onset_at_least_6_months boolean required Symptom onset at least 6 months prior to diagnosis, as assigned (Stanghellini 2016). true or false as assigned by the caller. magent does not take a history.
pathologic_bathing boolean required Pathologic bathing behavior (prolonged hot baths or showers), a supportive criterion that is not required for rome_iv_chs (Stanghellini 2016). true or false as assigned by the caller. magent does not examine the patient.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/rome_iv_chs Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

  • 1 to 25 items. Each item uses the same keys as the GET query parameters.
  • POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
  • The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
  • HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
  • Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
  • x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "after_prolonged_excessive_cannabis": "true",
      "fulfilled_last_3_months": "true",
      "onset_at_least_6_months": "true",
      "pathologic_bathing": "true",
      "relief_with_sustained_cessation": "true",
      "stereotypical_episodic_vomiting": "true"
    },
    {
      "after_prolonged_excessive_cannabis": "true",
      "fulfilled_last_3_months": "true",
      "onset_at_least_6_months": "true",
      "pathologic_bathing": "true",
      "relief_with_sustained_cessation": "true",
      "stereotypical_episodic_vomiting": "true"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/rome_iv_chs",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, Talley NJ",
        "doi": "10.1053/j.gastro.2016.02.011",
        "id": "stanghellini-2016",
        "pmid": "27147122",
        "source": "Gastroenterology. 2016;150(6):1380-1392",
        "title": "Gastroduodenal Disorders"
      },
      "formula": "rome_iv_chs",
      "formula_expression": "rome_iv_chs iff stereotypical_episodic_vomiting and after_prolonged_excessive_cannabis and relief_with_sustained_cessation and fulfilled_last_3_months and onset_at_least_6_months; pathologic_bathing is supportive and not required (Stanghellini 2016 Rome IV cannabinoid hyperemesis syndrome)",
      "criteria": [
        {
          "factor": "stereotypical_episodic_vomiting",
          "met": true
        },
        {
          "factor": "after_prolonged_excessive_cannabis",
          "met": true
        },
        {
          "factor": "relief_with_sustained_cessation",
          "met": true
        },
        {
          "factor": "fulfilled_last_3_months",
          "met": true
        },
        {
          "factor": "onset_at_least_6_months",
          "met": true
        },
        {
          "factor": "pathologic_bathing",
          "met": true
        }
      ],
      "pathologic_bathing": true,
      "rome_iv_chs": true
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, Talley NJ",
        "doi": "10.1053/j.gastro.2016.02.011",
        "id": "stanghellini-2016",
        "pmid": "27147122",
        "source": "Gastroenterology. 2016;150(6):1380-1392",
        "title": "Gastroduodenal Disorders"
      },
      "formula": "rome_iv_chs",
      "formula_expression": "rome_iv_chs iff stereotypical_episodic_vomiting and after_prolonged_excessive_cannabis and relief_with_sustained_cessation and fulfilled_last_3_months and onset_at_least_6_months; pathologic_bathing is supportive and not required (Stanghellini 2016 Rome IV cannabinoid hyperemesis syndrome)",
      "criteria": [
        {
          "factor": "stereotypical_episodic_vomiting",
          "met": true
        },
        {
          "factor": "after_prolonged_excessive_cannabis",
          "met": true
        },
        {
          "factor": "relief_with_sustained_cessation",
          "met": true
        },
        {
          "factor": "fulfilled_last_3_months",
          "met": true
        },
        {
          "factor": "onset_at_least_6_months",
          "met": true
        },
        {
          "factor": "pathologic_bathing",
          "met": true
        }
      ],
      "pathologic_bathing": true,
      "rome_iv_chs": true
    }
  ]
}

Response

Field Type Description
formula string rome_iv_chs
formula_expression string Stanghellini 2016 Rome IV CHS: stereotypical episodic vomiting, prolonged excessive cannabis use, relief with sustained cessation, last-3-months criteria, and 6-month onset; pathologic bathing is supportive and not required
pathologic_bathing boolean Caller-assigned supportive pathologic bathing flag. Reported separately; not required for rome_iv_chs.
rome_iv_chs boolean true only when all five required flags hold. pathologic_bathing is not required. Not a diagnosis.
criteria array Per-factor rows with factor and met for the five required flags plus supportive pathologic_bathing
citation object Stanghellini 2016 Gastroenterology citation
disclaimer string Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, Talley NJ",
    "doi": "10.1053/j.gastro.2016.02.011",
    "id": "stanghellini-2016",
    "pmid": "27147122",
    "source": "Gastroenterology. 2016;150(6):1380-1392",
    "title": "Gastroduodenal Disorders"
  },
  "formula": "rome_iv_chs",
  "formula_expression": "rome_iv_chs iff stereotypical_episodic_vomiting and after_prolonged_excessive_cannabis and relief_with_sustained_cessation and fulfilled_last_3_months and onset_at_least_6_months; pathologic_bathing is supportive and not required (Stanghellini 2016 Rome IV cannabinoid hyperemesis syndrome)",
  "criteria": [
    {
      "factor": "stereotypical_episodic_vomiting",
      "met": true
    },
    {
      "factor": "after_prolonged_excessive_cannabis",
      "met": true
    },
    {
      "factor": "relief_with_sustained_cessation",
      "met": true
    },
    {
      "factor": "fulfilled_last_3_months",
      "met": true
    },
    {
      "factor": "onset_at_least_6_months",
      "met": true
    },
    {
      "factor": "pathologic_bathing",
      "met": true
    }
  ],
  "pathologic_bathing": true,
  "rome_iv_chs": true
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP Code When
400 invalid_rome_iv_chs Rome IV CHS needs stereotypical episodic vomiting, cannabis-use onset, relief after cannabis cessation, and the 3-month/6-month timing flags (Stanghellini 2016). Returned before settlement; you are not charged.
400 invalid_flag boolean clinical flags must be true or false Returned before settlement; you are not charged.
400 invalid_items POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400 invalid_item_count items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400 invalid_item each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

  • Rome IV IBS — Apply the Mearin 2016 Rome IV IBS diagnostic criteria and return supporting_features_met (0-3) and whether the published IBS box holds (rome_iv_ibs).
  • Rome IV FD — Apply the Stanghellini 2016 Rome IV B1 functional dyspepsia criteria and return whether PDS (B1a), EPS (B1b), and the published FD box hold (rome_iv_fd).

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

  • HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
  • exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
  • HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
  • Execution is timeout-bounded and concurrency-capped.
  • Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.