Hematology · LIVE

GELF criteria

Apply the Brice 1997 GELF high-tumor-burden checklist and return low_burden or high_burden from eight caller-assigned items.

LIVE $0.005 USDC GET /api/calc/gelf

Markdown: /docs/gelf.md · Canonical: https://magentlab.com/docs/gelf

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply the Brice 1997 GELF high-tumor-burden checklist and return low_burden or high_burden from eight caller-assigned items.

When to use

When an agent already has follicular lymphoma findings as assigned by the caller and needs the published Brice 1997 GELF high-versus-low tumor-burden checklist.

When not to use

• Not a medical device and not a follicular-lymphoma diagnosis or a treatment-initiation or watchful-waiting order. magent does not examine the patient.
• This tool is the Brice 1997 original GELF high-tumor-burden checklist only. It is not FLIPI and not IPI. It is not modified GELF (LDH or β2-microglobulin).
• The caller assigns all eight items. magent does not measure nodes, spleen, counts, or effusions.
• High tumor burden is the published any-criterion rule only: any yes is high_burden; all absent is low_burden.

Formula

high tumor burden iff any of the 8 Brice 1997 GELF criteria

Citation

Title

Comparison in low-tumor-burden follicular lymphomas between an initial no-treatment policy, prednimustine, or interferon alfa: a randomized study from the Groupe d'Etude des Lymphomes Folliculaires

Authors

Brice P, Bastion Y, Lepage E, Brousse N, Haïoun C, Moreau P, Straetmans N, Tilly H, Tabah I, Solal-Céligny P

Source

J Clin Oncol. 1997;15(3):1110-1117

DOI

10.1200/JCO.1997.15.3.1110

Worked example

Also searched as

• GELF criteria
• Groupe d'Etude des Lymphomes Folliculaires
• Brice GELF
• GELF tumor burden
• follicular lymphoma GELF
• high tumor burden follicular lymphoma
• original GELF criteria

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/gelf?mass_gt_7cm=false&three_nodes_gt_3cm=false&b_symptoms=false&spleen_below_umbilicus=false&compression=false&effusion=false&leukemic_phase=false&cytopenia=false

Full URL: https://api.magentlab.com/api/calc/gelf?mass_gt_7cm=false&three_nodes_gt_3cm=false&b_symptoms=false&spleen_below_umbilicus=false&compression=false&effusion=false&leukemic_phase=false&cytopenia=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/gelf?mass_gt_7cm=false&three_nodes_gt_3cm=false&b_symptoms=false&spleen_below_umbilicus=false&compression=false&effusion=false&leukemic_phase=false&cytopenia=false"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/gelf Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "b_symptoms": "false",
      "compression": "false",
      "cytopenia": "false",
      "effusion": "false",
      "leukemic_phase": "false",
      "mass_gt_7cm": "false",
      "spleen_below_umbilicus": "false",
      "three_nodes_gt_3cm": "false"
    },
    {
      "b_symptoms": "false",
      "compression": "false",
      "cytopenia": "false",
      "effusion": "false",
      "leukemic_phase": "false",
      "mass_gt_7cm": "false",
      "spleen_below_umbilicus": "false",
      "three_nodes_gt_3cm": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/gelf",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Brice P, Bastion Y, Lepage E, Brousse N, Haïoun C, Moreau P, Straetmans N, Tilly H, Tabah I, Solal-Céligny P",
        "doi": "10.1200/JCO.1997.15.3.1110",
        "id": "brice-1997",
        "pmid": "9060552",
        "source": "J Clin Oncol. 1997;15(3):1110-1117",
        "title": "Comparison in low-tumor-burden follicular lymphomas between an initial no-treatment policy, prednimustine, or interferon alfa: a randomized study from the Groupe d'Etude des Lymphomes Folliculaires"
      },
      "formula": "gelf",
      "formula_expression": "high tumor burden iff any of the 8 Brice 1997 GELF criteria",
      "criteria": [
        {
          "factor": "mass_gt_7cm",
          "met": false
        },
        {
          "factor": "three_nodes_gt_3cm",
          "met": false
        },
        {
          "factor": "b_symptoms",
          "met": false
        },
        {
          "factor": "spleen_below_umbilicus",
          "met": false
        },
        {
          "factor": "compression",
          "met": false
        },
        {
          "factor": "effusion",
          "met": false
        },
        {
          "factor": "leukemic_phase",
          "met": false
        },
        {
          "factor": "cytopenia",
          "met": false
        }
      ],
      "tumor_burden": "low_burden"
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Brice P, Bastion Y, Lepage E, Brousse N, Haïoun C, Moreau P, Straetmans N, Tilly H, Tabah I, Solal-Céligny P",
        "doi": "10.1200/JCO.1997.15.3.1110",
        "id": "brice-1997",
        "pmid": "9060552",
        "source": "J Clin Oncol. 1997;15(3):1110-1117",
        "title": "Comparison in low-tumor-burden follicular lymphomas between an initial no-treatment policy, prednimustine, or interferon alfa: a randomized study from the Groupe d'Etude des Lymphomes Folliculaires"
      },
      "formula": "gelf",
      "formula_expression": "high tumor burden iff any of the 8 Brice 1997 GELF criteria",
      "criteria": [
        {
          "factor": "mass_gt_7cm",
          "met": false
        },
        {
          "factor": "three_nodes_gt_3cm",
          "met": false
        },
        {
          "factor": "b_symptoms",
          "met": false
        },
        {
          "factor": "spleen_below_umbilicus",
          "met": false
        },
        {
          "factor": "compression",
          "met": false
        },
        {
          "factor": "effusion",
          "met": false
        },
        {
          "factor": "leukemic_phase",
          "met": false
        },
        {
          "factor": "cytopenia",
          "met": false
        }
      ],
      "tumor_burden": "low_burden"
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Brice P, Bastion Y, Lepage E, Brousse N, Haïoun C, Moreau P, Straetmans N, Tilly H, Tabah I, Solal-Céligny P",
    "doi": "10.1200/JCO.1997.15.3.1110",
    "id": "brice-1997",
    "pmid": "9060552",
    "source": "J Clin Oncol. 1997;15(3):1110-1117",
    "title": "Comparison in low-tumor-burden follicular lymphomas between an initial no-treatment policy, prednimustine, or interferon alfa: a randomized study from the Groupe d'Etude des Lymphomes Folliculaires"
  },
  "formula": "gelf",
  "formula_expression": "high tumor burden iff any of the 8 Brice 1997 GELF criteria",
  "criteria": [
    {
      "factor": "mass_gt_7cm",
      "met": false
    },
    {
      "factor": "three_nodes_gt_3cm",
      "met": false
    },
    {
      "factor": "b_symptoms",
      "met": false
    },
    {
      "factor": "spleen_below_umbilicus",
      "met": false
    },
    {
      "factor": "compression",
      "met": false
    },
    {
      "factor": "effusion",
      "met": false
    },
    {
      "factor": "leukemic_phase",
      "met": false
    },
    {
      "factor": "cytopenia",
      "met": false
    }
  ],
  "tumor_burden": "low_burden"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• FLIPI — Sum the Solal-Céligny 2004 FLIPI adverse factors for follicular lymphoma and return low (0–1), intermediate (2), or high (≥3).
• IPI — Sum the Shipp 1993 five-factor International Prognostic Index (all ages) and return low (0–1), low_intermediate (2), high_intermediate (3), or high (4–5).

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.