Medications · LIVE

Fomepizole

Compute adult IV fomepizole loading and maintenance milligrams from body weight using the AACT 1999 ethylene glycol guideline schedule, with a 12-hour or 4-hour interval from the hemodialysis flag.

LIVE $0.005 USDC GET /api/calc/fomepizole

Markdown: /docs/fomepizole.md · Canonical: https://magentlab.com/docs/fomepizole

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute adult IV fomepizole loading and maintenance milligrams from body weight using the AACT 1999 ethylene glycol guideline schedule, with a 12-hour or 4-hour interval from the hemodialysis flag.

When to use

When an agent needs published AACT 1999 fomepizole milligram-per-kilogram arithmetic and must not invent an ethanol-as-antidote dose, an indication, or a prescription.

When not to use

• Not a medical device, not a prescription, and not Antizol. magent does not name a brand or choose a vial.
• Not an indication decision. magent does not decide whether to treat ethylene glycol or methanol poisoning.
• magent does not assay ethylene glycol or methanol.
• Adult IV milligram arithmetic only. Does not encode a Rumack nomogram or ethanol-as-antidote doses.

Formula

load_mg = weight_kg * 15; maintenance_10_mg = weight_kg * 10; maintenance_15_mg = weight_kg * 15; interval_hours = hemodialysis ? 4 : 12

Citation

Title

American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning

Authors

Barceloux DG, Krenzelok EP, Olson K, Watson W

Source

J Toxicol Clin Toxicol. 1999;37(5):537-560

DOI

10.1081/CLT-100102445

Worked example

Also searched as

• fomepizole dose
• ethylene glycol antidote
• methanol antidote
• AACT fomepizole
• fomepizole loading dose
• fomepizole hemodialysis

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/fomepizole?weight_kg=70&hemodialysis=false

Full URL: https://api.magentlab.com/api/calc/fomepizole?weight_kg=70&hemodialysis=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/fomepizole?weight_kg=70&hemodialysis=false"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/fomepizole Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "hemodialysis": "false",
      "weight_kg": "70"
    },
    {
      "hemodialysis": "false",
      "weight_kg": "70"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/fomepizole",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Barceloux DG, Krenzelok EP, Olson K, Watson W",
        "doi": "10.1081/CLT-100102445",
        "id": "barceloux-1999",
        "pmid": "10497633",
        "source": "J Toxicol Clin Toxicol. 1999;37(5):537-560",
        "title": "American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning"
      },
      "formula": "fomepizole",
      "formula_expression": "load_mg = weight_kg * 15; maintenance_10_mg = weight_kg * 10; maintenance_15_mg = weight_kg * 15; interval_hours = hemodialysis ? 4 : 12",
      "weight_kg": 70.0,
      "hemodialysis": false,
      "interval_hours": 12,
      "load_mg": 1050.0,
      "maintenance_10_mg": 700.0,
      "maintenance_15_mg": 1050.0
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Barceloux DG, Krenzelok EP, Olson K, Watson W",
        "doi": "10.1081/CLT-100102445",
        "id": "barceloux-1999",
        "pmid": "10497633",
        "source": "J Toxicol Clin Toxicol. 1999;37(5):537-560",
        "title": "American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning"
      },
      "formula": "fomepizole",
      "formula_expression": "load_mg = weight_kg * 15; maintenance_10_mg = weight_kg * 10; maintenance_15_mg = weight_kg * 15; interval_hours = hemodialysis ? 4 : 12",
      "weight_kg": 70.0,
      "hemodialysis": false,
      "interval_hours": 12,
      "load_mg": 1050.0,
      "maintenance_10_mg": 700.0,
      "maintenance_15_mg": 1050.0
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Barceloux DG, Krenzelok EP, Olson K, Watson W",
    "doi": "10.1081/CLT-100102445",
    "id": "barceloux-1999",
    "pmid": "10497633",
    "source": "J Toxicol Clin Toxicol. 1999;37(5):537-560",
    "title": "American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning"
  },
  "formula": "fomepizole",
  "formula_expression": "load_mg = weight_kg * 15; maintenance_10_mg = weight_kg * 10; maintenance_15_mg = weight_kg * 15; interval_hours = hemodialysis ? 4 : 12",
  "weight_kg": 70.0,
  "hemodialysis": false,
  "interval_hours": 12,
  "load_mg": 1050.0,
  "maintenance_10_mg": 700.0,
  "maintenance_15_mg": 1050.0
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

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Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.