Neurology · LIVE

OHTS-EGPS 5-year POAG risk

Compute the OHTS-EGPS 2007 Table 6 5-year primary open-angle glaucoma percent for untreated ocular hypertension from age, mean IOP, mean central corneal thickness, mean vertical cup-disc ratio, and mean Humphrey pattern standard deviation.

LIVE $0.005 USDC GET /api/calc/ohts

Markdown: /docs/ohts.md · Canonical: https://magentlab.com/docs/ohts

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the OHTS-EGPS 2007 Table 6 5-year primary open-angle glaucoma percent for untreated ocular hypertension from age, mean IOP, mean central corneal thickness, mean vertical cup-disc ratio, and mean Humphrey pattern standard deviation.

When to use

When an agent already has those five averaged baseline predictors for a person with ocular hypertension aged 30-80 and needs that paper's mapped 5-year POAG percent. Not a glaucoma diagnosis, drop order, or Gordon 2002 univariate table.

When not to use

• Not a medical device. Not a diagnosis of glaucoma. Not a drop order or treatment recommendation.
• Table 6 point system printed in Ophthalmology 2007 only. The paper's continuous Cox estimate (16.9% in the worked example) is not implemented: 5-year baseline survival and centering constants are not printed.
• No race parameter: African ancestry dropped out of the multivariate model once cup-disc ratio and corneal thickness were included. No diabetes or treatment term.
• Caller assigns age, IOP, pachymetry, disc, and Humphrey PSD. magent does not measure IOP or pachymetry and does not run perimetry. Clamps: age 30-80, IOP 20-32 mm Hg, CCT 475-650 microns.

Formula

OHTS-EGPS 2007 Table 6 points: age <45=0, 45 to <55=1, 55 to <65=2, 65 to <75=3, >=75=4; mean IOP mm Hg <22=0, 22 to <24=1, 24 to <26=2, 26 to <28=3, >=28=4; mean CCT microns >=600=0, 576 to <600=1, 551 to <576=2, 526 to <551=3, <=525=4; mean vertical cup-disc ratio <0.3=0, 0.3 to <0.4=1, 0.4 to <0.5=2, 0.5 to <0.6=3, >=0.6=4; mean Humphrey PSD dB <1.8=0, 1.8 to <2.0=1, 2 to <2.4=2, 2.4 to <2.8=3, >=2.8=4; sum 0-6 -> 4.0% (<=4.0%), 7-8 -> 10%, 9-10 -> 15%, 11-12 -> 20%, >12 -> 33% (>=33%); no race; no diabetes; not a glaucoma diagnosis

Citation

Title

A validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension

Authors

Ocular Hypertension Treatment Study Group; European Glaucoma Prevention Study Group; Gordon MO, Torri V, Miglior S, Beiser JA, Floriani I, Miller JP, Gao F, Adamsons I, Poli D, D'Agostino RB, Kass MA

Source

Ophthalmology. 2007;114(1):10-19

DOI

10.1016/j.ophtha.2006.08.031

Worked example

Also searched as

• OHTS-EGPS
• ocular hypertension glaucoma risk
• 5-year POAG risk
• Gordon 2007 glaucoma
• central corneal thickness glaucoma
• pattern standard deviation POAG
• OHTS risk points

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/ohts?age=55&iop_mm_hg=24&cct_microns=540&vertical_cd_ratio=0.4&psd_db=2.2

Full URL: https://api.magentlab.com/api/calc/ohts?age=55&iop_mm_hg=24&cct_microns=540&vertical_cd_ratio=0.4&psd_db=2.2

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/ohts?age=55&iop_mm_hg=24&cct_microns=540&vertical_cd_ratio=0.4&psd_db=2.2"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/ohts Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "age": "55",
      "cct_microns": "540",
      "iop_mm_hg": "24",
      "psd_db": "2.2",
      "vertical_cd_ratio": "0.4"
    },
    {
      "age": "55",
      "cct_microns": "540",
      "iop_mm_hg": "24",
      "psd_db": "2.2",
      "vertical_cd_ratio": "0.4"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/ohts",
  "items": [
    {
      "points": 11,
      "age": 55,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ocular Hypertension Treatment Study Group; European Glaucoma Prevention Study Group; Gordon MO, Torri V, Miglior S, Beiser JA, Floriani I, Miller JP, Gao F, Adamsons I, Poli D, D'Agostino RB, Kass MA",
        "doi": "10.1016/j.ophtha.2006.08.031",
        "id": "ohts-egps-2007",
        "pmid": "17070597",
        "source": "Ophthalmology. 2007;114(1):10-19",
        "title": "A validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension"
      },
      "formula": "ohts",
      "formula_expression": "OHTS-EGPS 2007 Table 6 points: age <45=0, 45 to <55=1, 55 to <65=2, 65 to <75=3, >=75=4; mean IOP mm Hg <22=0, 22 to <24=1, 24 to <26=2, 26 to <28=3, >=28=4; mean CCT microns >=600=0, 576 to <600=1, 551 to <576=2, 526 to <551=3, <=525=4; mean vertical cup-disc ratio <0.3=0, 0.3 to <0.4=1, 0.4 to <0.5=2, 0.5 to <0.6=3, >=0.6=4; mean Humphrey PSD dB <1.8=0, 1.8 to <2.0=1, 2 to <2.4=2, 2.4 to <2.8=3, >=2.8=4; sum 0-6 -> 4.0% (<=4.0%), 7-8 -> 10%, 9-10 -> 15%, 11-12 -> 20%, >12 -> 33% (>=33%); no race; no diabetes; not a glaucoma diagnosis",
      "cct_microns": 540.0,
      "iop_mm_hg": 24.0,
      "psd_db": 2.2,
      "risk_5y_percent": 20.0,
      "vertical_cd_ratio": 0.4
    },
    {
      "points": 11,
      "age": 55,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Ocular Hypertension Treatment Study Group; European Glaucoma Prevention Study Group; Gordon MO, Torri V, Miglior S, Beiser JA, Floriani I, Miller JP, Gao F, Adamsons I, Poli D, D'Agostino RB, Kass MA",
        "doi": "10.1016/j.ophtha.2006.08.031",
        "id": "ohts-egps-2007",
        "pmid": "17070597",
        "source": "Ophthalmology. 2007;114(1):10-19",
        "title": "A validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension"
      },
      "formula": "ohts",
      "formula_expression": "OHTS-EGPS 2007 Table 6 points: age <45=0, 45 to <55=1, 55 to <65=2, 65 to <75=3, >=75=4; mean IOP mm Hg <22=0, 22 to <24=1, 24 to <26=2, 26 to <28=3, >=28=4; mean CCT microns >=600=0, 576 to <600=1, 551 to <576=2, 526 to <551=3, <=525=4; mean vertical cup-disc ratio <0.3=0, 0.3 to <0.4=1, 0.4 to <0.5=2, 0.5 to <0.6=3, >=0.6=4; mean Humphrey PSD dB <1.8=0, 1.8 to <2.0=1, 2 to <2.4=2, 2.4 to <2.8=3, >=2.8=4; sum 0-6 -> 4.0% (<=4.0%), 7-8 -> 10%, 9-10 -> 15%, 11-12 -> 20%, >12 -> 33% (>=33%); no race; no diabetes; not a glaucoma diagnosis",
      "cct_microns": 540.0,
      "iop_mm_hg": 24.0,
      "psd_db": 2.2,
      "risk_5y_percent": 20.0,
      "vertical_cd_ratio": 0.4
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "points": 11,
  "age": 55,
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Ocular Hypertension Treatment Study Group; European Glaucoma Prevention Study Group; Gordon MO, Torri V, Miglior S, Beiser JA, Floriani I, Miller JP, Gao F, Adamsons I, Poli D, D'Agostino RB, Kass MA",
    "doi": "10.1016/j.ophtha.2006.08.031",
    "id": "ohts-egps-2007",
    "pmid": "17070597",
    "source": "Ophthalmology. 2007;114(1):10-19",
    "title": "A validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension"
  },
  "formula": "ohts",
  "formula_expression": "OHTS-EGPS 2007 Table 6 points: age <45=0, 45 to <55=1, 55 to <65=2, 65 to <75=3, >=75=4; mean IOP mm Hg <22=0, 22 to <24=1, 24 to <26=2, 26 to <28=3, >=28=4; mean CCT microns >=600=0, 576 to <600=1, 551 to <576=2, 526 to <551=3, <=525=4; mean vertical cup-disc ratio <0.3=0, 0.3 to <0.4=1, 0.4 to <0.5=2, 0.5 to <0.6=3, >=0.6=4; mean Humphrey PSD dB <1.8=0, 1.8 to <2.0=1, 2 to <2.4=2, 2.4 to <2.8=3, >=2.8=4; sum 0-6 -> 4.0% (<=4.0%), 7-8 -> 10%, 9-10 -> 15%, 11-12 -> 20%, >12 -> 33% (>=33%); no race; no diabetes; not a glaucoma diagnosis",
  "cct_microns": 540.0,
  "iop_mm_hg": 24.0,
  "psd_db": 2.2,
  "risk_5y_percent": 20.0,
  "vertical_cd_ratio": 0.4
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

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Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.